82 research outputs found
Forensic evaluation: A strategy for and results of an impact evaluation of a universal labor market program - The Swedish activity guarantee
To evaluate the effects of a universal program, i.e. all targeted get access, is associated with the problem that there are no individuals who represent the hypothetical or counterfactual state of being eligible to the program but not participating in it. In this study of a Swedish universal labor market program the Activity Guarantee we show how regional differences in the implementation of instructions on assignment to the program were utilized to create a control group representing the counterfactual state. After having gained access to a treatment and a control group, the authors evaluated the effects of the program on the probability of leaving unemployment and on the duration of unemployment. The effects estimated were statistically significant and indicate a clear positive effect of program participation. -- In dieser Analyse wird das Evaluierungsproblem untersucht, das entsteht, wenn die Effekte eines Programms untersucht werden sollen, das einschränkungslos für alle Mitglieder einer Zielgruppe gilt. Dann nämlich gibt es nicht mehr die Fälle, die den gegenteiligen Zustand repräsentieren, d.h. Anspruchsberechtigte, die nicht an dem Programm teilnehmen. In dieser Studie über ein in diesem Sinne universelles Arbeitsmarktprogramm in Schweden mit dem Titel Aktivitäts- Garantie wird gezeigt, wie regionale Unterschiede bei der Umsetzung der Vorschriften zur Zuweisung in das Programm genutzt werden, um eine Kontrollgruppe zu bilden. Nachdem der Zugang zu den Daten einer Teilnehmergruppe und einer Kontrollgruppe geklärt war, evaluierten die Autoren die Effekte des Programms auf die Abgangswahrscheinlichkeit aus und auf die Dauer der Arbeitslosigkeit. Die geschätzten Effekte waren statistisch signifikant und belegen einen eindeutig positiven Effekt einer Teilnahme an dem Programm.
Controle de oscilações em sistemas comutados com aplicações em eletrônica de potência
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.Este trabalho apresenta uma proposta para controle (geração) de oscilações em sistemas comutados. Baseado na forma de um oscilador não linear, é proposta uma metodologia de projeto de controladores para a obtenção de oscilações autônomas estáveis em sistemas dinâmicos (sem uso de sinais de referência externos). Os resultados obtidos através de simulações sobre os conversores buck, boost, duplo boost e inversor demonstram a validade do método proposto. Resultados experimentias obtidos em laboratório sobre o inversor e o conversor boost permitem validar a metodologia proposta. This work presents a proposal for control (generation) of oscillations on switched systems. Based in a nonlinear oscillator form, a controller design methodology is proposed to obtain stable autonomous oscillations in dynamic systems (without using external reference signals). The results obtained by means of simulation of buck, boost and double boost converters and an inverter demonstrate the proposed method validity. Experimental results concerning the inverter and the boost converter permits to validate the proposed methodology
Additional file 4 of Pascal short-pulse plus subthreshold endpoint management laser therapy for diabetic macular edema: the “sandwich technique”
Additional file 4: Graph S1. A Mean BCVA (logMAR) at baseline (A1) and after SWiT laser therapy (A2); B Mean CST (µm) at baseline (B1) and after SWiT laser therapy (B2)
An Improved Optimal Slip Ratio Prediction considering Tyre Inflation Pressure Changes
The prediction of optimal slip ratio is crucial to vehicle control systems. Many studies have verified there is a definitive impact of tyre pressure change on the optimal slip ratio. However, the existing method of optimal slip ratio prediction has not taken into account the influence of tyre pressure changes. By introducing a second-order factor, an improved optimal slip ratio prediction considering tyre inflation pressure is proposed in this paper. In order to verify and evaluate the performance of the improved prediction, a cosimulation platform is developed by using MATLAB/Simulink and CarSim software packages, achieving a comprehensive simulation study of vehicle braking performance cooperated with an ABS controller. The simulation results show that the braking distances and braking time under different tyre pressures and initial braking speeds are effectively shortened with the improved prediction of optimal slip ratio. When the tyre pressure is slightly lower than the nominal pressure, the difference of braking performances between original optimal slip ratio and improved optimal slip ratio is the most obvious
Birmingham News sleeve BN0055848
Barbara Robinson / Author of Best Christmas Pageant Ever which was adapted to a movie starring Loretta Swit / Hewitt-Trussville Elementary / She is going to talk about her work and do a writing seminar for 1st - 4th graders. / This assignment is set up for her talk with 3rd and 4th graders / Stripes 3rd [kid] / Lance Walker / Loni Anne Wallace / 2nd ponytail / [Work order included
Let’s play with Le Corbusier
[EN] The research focuses on the possibility of transferring theoretical ideas of Le Corbusier into educational programs
of the very young children – between three and six. The worldwide development of civilization changed the natural
environment of the human. For the average European citizen a city is more natural place for living than a forest.
Simultaneously, in these days many inhabitants present an extremely conformist approach to life and to the surrounding
space. The participation of members of the society in the shaping of public spaces is possible only through the involvement
and practice, but the democratic responsibility does not appears out of nowhere. It must be fostered and nurtured as early as
in childhood. According to developmental psychology, children in the age of 3-6 are very susceptible to the acquisition of new
skills and learn it in an intuitive way. The proper education program using Le Corbusier’s lectures and theory could help
them to understand the space better. The seeming simplicity of above rules is an advantage in this case – thereby it can be
explained to even such an audience as small children. On the other hand, some kind of abstract and hidden difficulty included
in this theory becomes an opportunity to create a very absorbing and stimulating workshops that follow the needs of younger
and older children. Le Corbusier’s legacy includes not only physical issues and can be used in many different ways. As Pablo
Picasso once stated: every child is an artist, the problem is staying an artist when you grow up. For those reasons,
incorporating such an innovative strategy for kids’ education reveals a great potential.[ES] Los estudios realizados enfocan en comprobar las posibilidades de usar las ideas teóricas de Le Corbusier en los
programas educativos para niños de tres a seis años. El desarrollo de la civilización ha cambiado el entorno natural del ser
humano - una ciudad para el ciudadano promedio de Europa es un lugar más natural para vivir que el bosque. Al mismo
tiempo, hay que reconocer que muchas personas muestran el enfoque muy conformista a la vida, tanto al espacio
circundante. Esta situación se podría mejorar mediante la participación consciente de los miembros de la sociedad en la
creación del espacio público, su compromiso y la práctica. Pero la responsabilidad democrática no aparece sola, se debe
estimularla y nutrir ya en la infancia. De acuerdo con la psicología del desarrollo, los niños de 3 a 6 años son muy
susceptibles a la adquisición de nuevas habilidades y aprenden de una manera intuitiva. Programa educativo que utiliza los
cursos y la teoría de Le Corbusier puede ayudarles a entender mejor el medio ambiente. La aparente sencillez de los
principios proclamados por él en este caso es una ventaja. La abstracción y escondidas dificultades incluidas en ellos,nos
permiten a crear actividades estimulantes que correspondan a las necesidades de los niños pequeños, tanto y mayores. Como
afirmo Pablo Picasso: "Todo niño es un artista. El problema es cómo mantenerse siendo niño una vez que se ha crecido"Swit-Jankowska, B. (2016). Let’s play with Le Corbusier. En LE CORBUSIER. 50 AÑOS DESPUÉS. Editorial Universitat Politècnica de València. 2175-2184. https://doi.org/10.4995/LC2015.2015.891OCS2175218
Additional file 1 of Pascal short-pulse plus subthreshold endpoint management laser therapy for diabetic macular edema: the “sandwich technique”
Additional file 1: Figure S1. A Representative image of DME. B Highly magnified RPE cell activated through SWiT laser photostimulation and intranuclear heat shock factor (HSF-1) stimulation to generate HSPs (heat shock proteins), with subsequent anti-apoptotic factor (Bcl2) formation and inflammation factor (TNF-alpha) depletion
Demographics and outcomes of hepatitis B and D: a 10-year retrospective analysis in a Swiss tertiary referral center
Background
Hepatitis B virus (HBV) is a major global health challenge with approximately 250–350 mil- lion chronically infected individuals. An improved understanding of the demographic fea- tures and outcomes of chronic HBV infection and hepatitis D virus (HDV) infection in low- endemic areas may improve prevention, early identification and management both at indi- vidual and community levels. Here, we retrospectively analyzed the demographic and clini- cal characteristics, treatment rates and outcomes of adult patients with chronic HBV infection with or without HDV coinfection examined at Lausanne University Hospital, Swit- zerland over a 10-year period.
Methods
We analyzed the medical records of all adult patients with chronic HBV and HDV infection examined in our center between 2007 and 2016. Liver-related outcome was defined as the occurrence of cirrhosis, hepatocellular carcinoma, liver transplantation or liver-related death. Analyses were performed using logistic regression and results were reported as odds ratio (OR) and 95% confidence interval (CI).
Results
Of 672 consecutive patients, 421 (62.6%) were male, median age was 36 years (interquar- tile range, 28–46 years), and 233 (34.7%) were of African origin. The prevalence of HDV coinfection was 7.1% and the proportion of anti-HDV-positive patients with detectable HDV RNA was 70.0%. In multivariate analysis, HDV coinfection was the strongest predictor for liver-related outcome (OR 6.06, 95% CI 2.93–12.54, p<0.001), followed by HBeAg positivity (OR 2.47, 95% CI 1.30–4.69, p = 0.006), age (OR per 10-year increase 2.03, 95% CI 1.63–2.52, accuracy of the multivariate model was high (receiver operator characteristic area under the curve 0.81).
Conclusion
This retrospective study underscores the importance of migration in the epidemiology of chronic hepatitis B in low-endemic areas. HDV coinfection, HBeAg positivity and age pre- dicted liver-related outcomes while female sex had a protective effect
White-to-opaque switching in natural <i>MTL</i>a/α strains of <i>C. albicans</i> at 37°C.
<p>White cells of two <i>MTL</i><b>a</b>/α strains (CY110 and RVVC10) were plated onto Lee's glucose and Lee's GlcNAc medium plates and cultured in air or 5% CO<sub>2</sub> at 37°C for 3 to 4 days. At this temperature, white cell colonies containing filamentous swollen cells could be stained red. Cellular morphologies were examined to confirm the cellular phenotypes. *, the switching frequencies (% of average ± SD) of these samples represented the percentages of colonies containing opaque cells, including opaque, opaque-sectored, and white-opaque mixed colonies. Swit. Freq., switching frequency. Wh, white cells/colonies. Op, opaque cells/colonies. Scale bar, 10 µm. (A) White-to-opaque switching of CY110 at 37°C. (B) White-to-opaque switching of RVVC10 at 37°C. (C) Expression of GFP in the reporter strains of <i>WOR1/WOR1::WOR1p-GFP</i>, <i>WH11/WH11::WH11p-GFP</i>, and <i>EFG1/EFG1::EFG1p-GFP</i>. The parent strain of these strains was CY110 (<i>MTL</i><b>a</b>/α). Opaque-sectored colonies grown on Lee's GlcNAc medium plates (without phloxine B) were microscopically examined. BF, bright field.</p
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