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Wireless capsule endoscopy for pediatric small-bowel disease. (I.F.6.101)
No full textOBJECTIVE: Although capsule endoscopy (CE) is becoming an increasingly popular procedure, only recently data
on its clinical application in pediatric gastroenterology are just emerging. Our aim is to investigate the
diagnostic value of CE in small intestine diseases and to determine its safety, tolerance, and
applicability in a large number of pediatric patients referred to our Tertiary Center of Pediatric
Gastroenterology Unit, University of Parma.
METHODS: A total of 87 Italian patients, 49 of which were male with an age range from 18 months to 18 yr with
a suspected small-bowel disease (inflammatory bowel disease 37%, polyps 38%, obscure
gastrointestinal bleeding 24%, malabsorption 1%), were investigated with the M2A capsule (GIVEN
Imaging Ltd., Yoqneam, Israel).
RESULTS: A total of 77 patients swallowed the capsule, while in 10 it was endoscopically positioned (age range
1.5–11 yr, median age 5.3 yr). Eighty patients naturally evacuated the capsule, one patient needed
surgery. The capsule evidenced pathological findings in 62 patients (71%), ileal lymphoid nodular
hyperplasia in four subjects (5%), it was negative in 18 subjects (21%), and technically failed in three
subjects (3%). In 21 out of 28 patients with known polyposis and in all the five patients with
suspected polyposis, small-bowel polyps were found. In 16 out of 22 patients suffering from known
inflammatory bowel disease (Crohn’s disease colitis or indeterminate colitis), small intestine lesions
were found. CE examination identified a possible small intestine bleeding source in 13 out of 21
patients with suspected obscure gastrointestinal bleeding. In 5 out of 10 patients with suspected
small-bowel inflammatory disease, CE evidenced ileum lesions suggesting Crohn’s disease, which was
subsequently confirmed through diagnostic procedures and the clinical history. A patient with
malabsorption presented a negative capsule study.
CONCLUSIONS: Our experience, which includes the largest number of pediatric patients and the youngest child
reported in literature, confirms that CE is a very useful system for the clinical work in suspected
small-bowel diseases in infancy. The high rate of positive examination is due to the very careful
selection of the patients, obligatory to conduct a safe examination since CE is not highly tested in
children
Gastro-oesophageal reflux and endoscopic antireflux technique: personal experience with endocich
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Ileoscopy with videocapsule and inflammatory bowel disease: a new diagnostic strategy? A new requirement to meet?
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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