80 research outputs found
Drawings & details, residence, Salt Lake City, B. F. Tibby
No full textA set of architectural plans by Liljenberg & Sundberg, Architets & ENgineers, for the B. F. Tibby residence in Salt Lake City (designed 1911
Modeling and remodeling of human extraction sockets
No full textIntroduction: the available studies on extraction wound repair in humans are affected by significant limitations and failed to evaluate tissue alterations occurring in all compartments of the hard tissue defect.
Aim: monitor during a 6 month period the healing of human extraction sockets and include a semi-quantitative analysis of tissues and cell populations involved in various stages of the processes of modeling/remodeling.
Materials & Methods: 27 biopsies, representative of the early (2-4 weeks; n= 10), intermediate (6-8 weeks; n= 6), and late phase (12-24 weeks; n= 11) of healing, were collected and analyzed.
Results: granulation tissue that was present in comparatively large amounts in the early healing phase of socket healing, was in the interval between the early and intermediate observation phase replaced with provisional matrix and woven bone. The density of vascular structures and macrophages slowly decreased from 2-4 weeks over time. The presence of osteoblasts peaked at 6-8 weeks and remained almost stable thereafter; a small number of osteoclasts were present in few specimens at each observation interval.
Conclusions: the present findings demonstrated that great variability exits in man with respect to hard tissue formation within extraction sockets. Thus while a provisional connective tissue consistently forms within the first weeks of healing, the interval during which mineralized bone is laid down is much less predictable
The alveolar process of the edentulous maxilla in periodontitis and non-periodontitis subjects.
No full textBACKGROUND:
Early implant failures may document that the bone tissue or the wound-healing process following installation surgery was compromised. Subjects who have lost teeth for periodontal reasons exhibit more earlier implant failures than subjects who had experienced tooth loss for other reasons.
AIM:
To describe the tissue of the fully healed extraction sites in subjects who had lost teeth as a result of periodontitis or for other reasons.
MATERIAL AND METHODS:
Thirty-six otherwise healthy, partially dentate subjects with fully healed edentulous portions in the posterior maxilla were included. Nineteen of these subjects had lost teeth because of advanced periodontitis (group P) and 17 for other reasons (group NP). Using a trephine drill, a 4-6 mm long hard tissue specimen was harvested. The biopsies were decalcified, embedded in paraffin, sectioned, stained and examined.
RESULTS:
The edentulous posterior maxilla was comprised of 47.1 ± 11% lamellar bone, 8.1 ± 7.1% woven bone, 4.3 ± 3.1% osteoid and 16.5 ± 10.4% bone marrow. There were no significant differences in the tissue composition of post-extraction sites of (i) P and NP subjects and (ii) premolar and molar sites.
CONCLUSION:
More than 50% of the edentulous maxilla was comprised of mineralized bone (lamellar and woven bone). The bone trabeculae frequently appeared to have a random orientation. The direction of the trabeculae rather than the lack of mineralized bone tissue may explain the clinical impression that the bone in the posterior maxilla provides limited resistance to mechanical instrumentation
Osseointegration in periodontitis susceptible individuals
No full textOBJECTIVES:
The aim of the present study was to examine tissue integration of implants placed (i) in subjects who had lost teeth because of advanced periodontal disease or for other reasons, (ii) in the posterior maxilla exhibiting varying amounts of mineralized bone.
MATERIAL AND METHODS:
Thirty-six subjects were enrolled; 19 had lost teeth because of advanced periodontitis (group P) while the remaining 17 subjects had suffered tooth loss from other reasons (group NP). As part of site preparation for implant placement, a 3 mm trephine drill was used to remove one or more 2 mm wide and 5-6 mm long block of hard tissue [biopsy site; Lindhe et al. (2011). Clinical of Oral Implants Research, DOI: 10.1111/j.1600-0501.2011.02205.x]. Lateral to the biopsy site a twist drill (diameter 2 mm) was used to prepare the hard tissue in the posterior maxilla for the placement of a screw-shaped, self-tapping micro-implant (implant site). The implants used were 5 mm long, had a diameter of 2.2 mm. After 3 months of healing, the micro-implants with surrounding hard tissue cores were retrieved using a trephine drill. The tissue was processed for ground sectioning. The blocks were cut parallel to the long axis of the implant and reduced to a thickness of about 20 μm and stained in toluidine blue. The percentage of (i) implant surface that was in contact with mineralized bone as well as (ii) the amount of bone present within the threads of the micro-implants (percentage bone area) was determined.
RESULTS:
Healing including hard tissue formation around implants placed in the posterior maxilla was similar in periodontitis susceptible and non-susceptible subjects. Thus, the degree of bone-to-implant contact (about 59%) as well as the amount of mineralized bone within threads of the micro-implant (about 45-50%) was similar in the two groups of subjects. Pearson's coefficient disclosed that there was a weak negative correlation (-0.49; P < 0.05) between volume of fibrous tissue (biopsy sites) and the length of bone to implant contact (BIC) while there was a weak positive correlation (0.51; P < 0.05) between the volume of bone marrow and BIC
Bone tissue in different parts of the edentulous maxilla and mandible.
No full textBACKGROUND:
The composition of the fully healed edentulous ridge of the posterior maxilla was recently examined and was found to contain about 50% mineralized bone and 16% bone marrow.
AIM:
The objective was to examine the composition of the tissue of the fully healed ridge in different portions of the maxilla and the mandible in partially dentate subjects.
MATERIAL AND METHODS:
Eighty-seven healthy subjects were included. A trephine drill was used to harvest hard tissue specimens. The biopsies were decalcified, embedded in paraffin, sectioned, stained, and examined using a point-counting procedure.
RESULTS:
The marginal portion of the jaws almost consistently contained a cortical cap that was significantly wider in the mandible than in the maxilla and twice as wide in the anterior as in the posterior segments of the mandible. Lamellar bone and bone marrow were the dominating tissue elements. Lamellar bone occupied about 63% of the tissue in the mandible and 46% in the maxilla. The maxilla contained about 23% bone marrow as compared to 16% in the mandible. In the mandible, 70% (anterior) and 57% (posterior) were made up of lamellar bone. In the maxilla, the proportion of lamellar bone in the anterior and posterior segments was similar (about 45%). Bone marrow occupied close to 40% of the anterior maxilla, while in the posterior maxilla and the anterior and posterior mandible marrow comprised between 13 and 18%.
CONCLUSION:
Marked differences existed with respect to tissue composition of the edentulous ridge between the maxilla and the mandible. The cortical crest was wider in the mandible than in the maxilla, and widest in the symphysis region of the mandible. The proportion of bone marrow was greater in the maxilla than in the mandible. The maxillary front tooth region was poor in lamellar bone but rich in bone marrow, while the anterior mandible contained large amounts of mineralized bone but small amounts of bone marrow
B-1a cells and plasma cells in periodontitis lesions
No full textBACKGROUND AND OBJECTIVE: Host response mechanisms in periodontal tissues are complex and involve numerous systems of interactions between cells. The B-cell lineage seems to predominate in chronic periodontitis lesions. The aim of the present investigation was to study the correlation between inflammatory cells and some functional markers in gingival lesions obtained from subjects with severe chronic periodontitis. MATERIAL AND METHODS: Thirty-eight Caucasian subjects volunteered to take part in the study. A gingival biopsy from one randomly selected diseased proximal site (probing pocket depth < 6 mm and bleeding on probing positive) was obtained from each patient. Immunohistochemical preparation was used to identify inflammatory cells and functional markers. Correlations between the different percentages of cell markers were analyzed by pairwise correlation. RESULTS: B cells (B-1a and B-2 cells) occurred in larger proportions than T cells and plasma cells. A statistically significant correlation was found between the percentage of B-1a cells and plasma cells and between all B lymphocytes and plasma cells. About 60% of B lymphocytes exhibited autoreactive features. CONCLUSION: It is suggested that B-1a cells constitute a significant part of the host response in periodontitis lesions and that plasma cells may develop from both B-2 and B-1a cells
A troublesome emergence:A marketing primer on Russian retail banking
No full textThe transition process of the formerly socialist economies of Eastern Europe dates back more than a decade. Whereas a few countries now entering the European Union experience significant progress some others, most notably the former CIS-countries including Russia, lag behind. Despite the central role of its subject matters for such market development, marketing has conceded ground to economics concerning the understanding of transition economies. This paper attempts to provide a remedy in this regard by presenting the results of a study undertaken in the retail banking sector in Saint Petersburg. Central to the argument is the idea that by looking into both horizontal and vertical market features, here competition and consumer loyalty, marketing provides an analysis where patterns appear which are not evident in conventional neoclassical scrutiny.transition economy; market construct; competition; consumer loyalty
B-1a cells in experimental gingivitis in humans
No full textBACKGROUND: Although previous studies revealed the presence of autoreactive B cells (B-1a cells) in periodontitis lesions, no evidence was provided for an active role of such cells in the host response to microbial challenge. The aim of the present investigation was to study the reaction of B-1a cells to de novo plaque formation in subjects who were treated for severe chronic periodontitis. METHODS: Fifteen white subjects with generalized, severe chronic periodontitis volunteered. Surgical periodontal therapy was performed in all quadrants of each subject after a period of infection control. After 6 months of healing (baseline), two gingival biopsies were harvested from each patient (probing depth >4 mm and no bleeding on probing; healed sites). The experimental gingivitis model was applied, and plaque accumulation was allowed for 3 weeks. Two additional biopsies were collected and prepared for immunohistochemical analysis on day 21. RESULTS: The biopsies retrieved after 3 weeks of plaque accumulation contained larger proportions of CD19+ and CD5+ cells (B-1a cells) than biopsies representing baseline (healed sites) (7.38% +/- 2.80% versus 5.96% +/- 2.48%). The tissue fraction of cells carrying the markers for CD3 (T cells), CD19 (B cells), and Bcl2 (apoptosis-associated marker) were significantly larger in tissue samples collected after 3 weeks of plaque accumulation than in specimens from baseline (healed sites). CONCLUSION: Autoreactive B cells (B-1a cells) are involved in the host response to microbial challenge in subjects with chronic periodontitis
On the use of real-time mortality data in modelling and analysis during an epidemic outbreak - underlying data
No full textThis project contains the primary data set analyzed in the paper "On the use of real-time mortality data in modelling and analysis during an epidemic outbreak ". The data was generated by downloading the DT-series daily from the Public Health Agency of Sweden between 2020-04-02 and 2020-07-09.
This project contains the following files:
FHM_Covid_Download.zip. (Zip-archive of raw downloaded files with Swedish deaths data.)
swedish_covid_deaths_data.csv. (Swedish deaths data collated from the raw data files in a .csv format.)
swedish_covid_deaths_data.xlsx. (Swedish deaths data collated from the raw data files in a .xlsx format.)
swedish_covid_deaths_OGR.R. (R-script to generate graphs and nowcasts in the paper.)
MDAR author checklist.pdf (Completed MDAR reporting checklist
- …
