13,366 research outputs found
José Luis Romero - 01
José Luis Romero de pie, Ana María Barrenechea, Bernardo Canal Feijóo, Luis Aznar y Gilda Lamarque de Romero Bres
¿EL DESARROLLO DE LA INTELIGENCIA ESPACIAL EN LA FORMACIÓN PROFESIONAL ÁREA DE PATRONAJE¿
Jiménez Cecilia, Ana María; director de proyecto: Beltrán Aznar, David2020-2021Curso de Formación Pedagógica y Didáctica para Profesorado de Formación Profesional y DeportivaFacultad de Estudios Sociales y Lenguas Aplicada
TÉCNICAS DE DEPILACIÓN
Ponce Ramírez, Ana María; director de proyecto: Beltrán Aznar, David2020-2021Curso de Formación Pedagógica y Didáctica para Profesorado de Formación Profesional y DeportivaFacultad de Estudios Sociales y Lenguas Aplicada
Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility
14 pags., 7 figs., 3 tabs.Hybrids of RNA with arabinonucleic acids 2′F-ANA and ANA have very similar structures but strikingly different thermal stabilities. We now present a thorough study combining NMR and other biophysical methods together with state-of-the-art theoretical calculations on a fully modified 10-mer hybrid duplex. Comparison between the solution structure of 2′F-ANA•RNA and ANA•RNA hybrids indicates that the increased binding affinity of 2′F-ANA is related to several subtle differences, most importantly a favorable pseudohydrogen bond (2′F-purine H8) which contrasts with unfavorable 2′-OH-nucleobase steric interactions in the case of ANA. While both 2′F-ANA and ANA strands maintained conformations in the southern/eastern sugar pucker range, the 2′F-ANA strand's structure was more compatible with the A-like structure of a hybrid duplex. No dramatic differences are found in terms of relative hydration for the two hybrids, but the ANA•RNA duplex showed lower uptake of counterions than its 2′F-ANA•RNA counterpart. Finally, while the two hybrid duplexes are of similar rigidities, 2′F-ANA single strands may be more suitably preorganized for duplex formation. Thus the dramatically increased stability of 2′F-ANA•RNA and ANA•RNA duplexes is caused by differencesin at least four areas, of which structure and pseudohydrogen bonding are the most important. © The Author(s) 2010. Published by Oxford University Press.Spanish Ministerio de Ciencia e Innovacion (grants
CTQ2007-68014-C02-02 to CG and BIO2009-10964 to
MO); Fundacion Marcelino Botin (grant to MO);
Canadian Institutes for Health Research (grant to
M.J.D.); Natural Sciences and Engineering Research
Council of Canada (postgraduate scholarship to
J.K.W.). Funding for open access charge: Canadian
Institutes for Health Research
Description and comparison of methods for the determination of anti-sars-COV-2 antibodies
Trabajo Integrador Final (Especialista en Bioquímica Clínica Área Inmunología) - - Universidad Nacional de Córdoba. Facultad de Ciencias Químicas, 2022.Fil: Aznar, Patricia Marcela. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina.Fil: Aznar, Patricia Marcela. Tucumán. Gobierno de la Provincia de Tucumán. Ministerio de Salud. Laboratorio de Salud Pública. Sección Inmunología; Argentina.The SARS-COV-2 pandemic had an impact with more than 570 million cases and more than 6.8 million deaths as recorded by the United Nations by July 2022. Within the diagnostic context, a few immunological techniques for the detection of anti-SARS-CoV-2 IgG antibodies emerged, including Chemiluminescent Microparticle Immunoassay (CMIA) and Enzyme-Linked Immunosorbent Assay (ELISA). This study aimed to compare three detection techniques that have different methodological basis. The study was observational, cross-sectional and retrospective in design. Materials and methods: Serum samples were processed by the following methodologies: CMIA and “in-house” ELISA. Results: The methodologies were quantitatively evaluated by the correlation method, and qualitatively by assessing individual and simultaneous sensitivity and specificity. Conclusions: These methodologies were designed in a health emergency context so they do not have a gold standard; thus, different algorithms are proposed to improve both the sensitivity and specificity of the detection of SARS-CoV-2 antibodies.2024-10-31Fil: Aznar, Patricia Marcela. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina.Fil: Aznar, Patricia Marcela. Tucumán. Gobierno de la Provincia de Tucumán. Ministerio de Salud. Laboratorio de Salud Pública. Sección Inmunología; Argentina
Upstream regulation, factor demand and productivity: Cross-industry differences in OECD countries, 1975–2007
Desde los feminismos : Patty Chang
Fil: Aznar, Sagrario. Universidad Complutense de Madrid; EspañaFil: Aznar, Sagrario. Universidad Nacional de Educación a Distancia; España.El presenta artículo analiza la obra de la artista chino-norteamericana Patty Chang, que en sus obras explora las construcciones simbólicas planteadas por Occidente y por Oriente. A través de elementos de tipo biográfico, cuestiona aquellas cimentaciones que se realizan por medio del lenguaje. Pero además, las obras artísticas de Chang revelan contradicciones dentro del propio feminismo -blanco, heterosexual y burgués- que deja afuera a quienes que no se ajustan a la norma. Este es el caso de las mujeres inmigrantes que se encuentran atravesadas por la fricción entre sus tradiciones y la absorción de la cultura que las recibe
Representações da sexualidade na obra de Ana Saldanha
Mestrado em Línguas, Literaturas e CulturasA presente dissertação analisa as diferentes representações da sexualidade na obra literária para jovens de Ana Saldanha. A leitura analítica incide sobre as narrativas da autora que abordam a temática da sexualidade juvenil e as suas problemáticas, com o objetivo de estudar a forma como as mesmas contribuem para a construção da identidade pessoal e sexual do potencial recetor juvenil. Desta forma, pretende-se detetar os conflitos psicológicos dos protagonistas, os seus valores e problemas, assim como os novos valores, problemas e preocupações sociais que emergem das narrativas; compreender de que forma a autora exprime a sua capacidade em observar o quotidiano e as relações humanas; identificar os pilares em que se apoia o universo social em estudo (família, escola, grupo de amigos); enquadrar as personagens numa sociedade pós-industrial e de informação que exige ao adolescente uma superação de desafios e de novos problemas.This dissertation analyzes the different representations of sexuality in Ana Saldanha’s literary work for youth. The analytical reading focuses on the author's narratives that address the issue of teenage sexuality and its problems, aiming to study their contribution in the construction of personal and sexual identity of the potential juvenile receiver. Thus, it is intended to detect the psychological conflicts of the protagonists, their values and problems, as well as the new values, social concerns and problems that emerge from the narratives; understand how the author expresses her ability to observe daily life and human relations; identify the pillars on which relies the social universe under study (family, school, friends); framing the characters in a post-industrial and information society which requires the teenager to relentlessly surmount challenges and new problems
- …
