25 research outputs found
Character Education of Prof. Dr. KH. Asep Saefuddin Chalim, MA (Analysis of the Poems in the Book of Dhalilun Najah)
No full textEducation is the key to civilization, where instilling good character values will strengthen the character foundations of the nation's children. From this literary work, the authors want to convey a meaning contained in it. Dhalilun Najah's book Clue to success of Prof. Dr. KH. Asep Saefuddin Chalim, MA. The book is a book published in 2018 which will be researched and reviewed in the contents of the book. What kind of clues to success do you offer? Prof. Dr. KH. Asep Saefuddin Chalim, MA so that you can achieve a dream and can form character. This research aims to the poems in Dhalilun Najah related to the character values contained in Prof. Dr. KH. Asep Saefuddin Chalim, MA., and analyze Prof.'s character education learning model. Dr. KH. Asep Saefuddin Chalim, MA in the poetry of Dhalilun Najah. By using the type of literature review research (Library Research). The approach used in this study is qualitative. The data source in this research is the book Dhalilun Najah by Prof. Dr. KH. Asep Saefuddin Chalim, MA chapter on poetry pages 57 to 66. The results of the research that have been examined by the author are 1) the character values contained in the poems of Dhalilun Najah by Prof. Dr. KH. Asep Saefuddin Chalim, MA, among others: a) Religious, b) Tolerance, c) Discipline, d) Hard work, e) Independence, f) Love of Peace, g) Love of Reading, h) Responsibility, these eight characters are contained in Dhalilun Najah's poetry which is the basis for character education in the book by Prof. Dr. KH. Asep Saefuddin Chalim, MA. 2) The character education learning model in the poetry of Dhalilun Najah by Prof. Dr. KH. Asep Saefuddin Chalim, MA uses an information processing model which this model has four components, namely: a) approach, b) learning strategy, c) method, d) learning technique
ISOLASI Rhizopus oligosporus PADA BEBERAPA INOKULUM TEMPE DI KABUPATEN BANYUMAS
No full textTempe merupakan makanan tradisional asli Indonesia. Tempe mengandung gizi yang cukup tinggi, mencakup 25% protein, 5% lemak, 4% karbohidrat serta kaya akan mineral dan vitamin B12. Sentra produksi tempe di Indonesia paling banyak di temui di Jawa Tengah, dan salah satunya ada di Kabupaten Banyumas. Tekstur tempe yang kompak dan berwarna putih tercipta dari hasil kerja jamur genus Rhizopus, yang ditambahkan sebagai inokulum pada saat pembuatan tempe. Salah satu jenis jamur yang sering dijumpai dalam ragi tempe adalah Rhizopus oligosporus. Penelitian ini bertujuan untuk mengisolasi jamur R. oligosporus dari beberapa inokulum tempe di Kabupaten Banyumas. 56 jamur diisolasi dari inokulum tempe. Semua isolat termasuk dalam genera Rhizopus. 19 diantaranya dipilih berdasarkan warna konidia, yang terdiri dari isolat dengan konidia coklat keabu-abuan, dan abu-abu. Pengamatan makroskopik dan mikroskopik menunjukkan bahwa isolat terpilih adalah R. oligosporus.</jats:p
POLITIK HUKUM NASIONAL TENTANG LEMBAGA KEUANGAN SYARIAH DI INDONESIA
No full textAbstrac
This article also reinforce the opinion of political Islam movement which points out
that enforcement of Islamic sharia must be done through street power. In the economic
sphere, this movement took gradualist strategyand democratic. Figures of the Islamic sharia
fighters in the economy: PM Saefuddin, Karnaen Perwataatmaja, M. Amin Aziz, Mohammad
Shafi Antonio, Amin Suma, Adiwarman Karim, Zaenal Arifin, and Riawan Amen. Indicators
that show the truth of the conclusion of this dissertation can be seen that: the establishment of
Islamic banks in the world, like: Egyptian Bank and the Bank Mit Ghamr Social Nasr, Faisal
Islamic Bank, a commercial banks, Islamic International Bank for Investment and
Development, the government's political elite turned out to involve , the role of government is
very big, either in the form of capital regulation.
Keywords: Islamic financial institutions, legal policy, street powe
Metalloproteinase-9 gene variants and risk for hypertension among ethnic Javanese
No full textBackground
Hypertension is associated with endothelial-dependent vasodilation disorders, due to reduced nitric oxide (NO) availability and excessive angiotensin II (ANG-II) activation. The objective of this study was to determine the association between matrix metallopeptidase 9 (MMP-9) gene polymorphism and hypertension in ethnic Javanese in the 40-80 year age group.
Methods
This was a case-control study on 50 PROLANIS patients of family doctors meeting the inclusion criteria and 50 controls without hypertension. Subjects were hypertensive patients with constant systolic arterial pressure of >140 mmHg and diastolic arterial pressure of >90 mmHg, confirmed in three successive measurements The observed parameters were degree of MMP-9 polymorphism, and NO and ANG-II levels. Matrix metallopeptidase 9 polymorphism was determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) using the SmaI restriction enzyme. MMP-9 polymorphisms were indicated by variation in band patterns. Degree of polymorphism in cases and controls were compared with NO and ANG-II levels in both groups. Data analysis was done using independent t-test.
Results
The heterozygous (3 band) to normal (2 band) MMP-9 genotype ratio was 3:1 in hypertensives, but balanced in controls. In hypertensives, heterozygous GA and homozygous AA genotype frequencies were respectively 3.198 and 1.548 times higher than that of the GG genotype (p=0.008 and p=0.726). There was a statistically significant differences of NO and Ang-II levels between cases and controls (p=0.000 and p=0.000; respectively).
Conclusion
Matrix metallopeptidase 9 gene polymorphisms in hypertensive ethnic Javanese are associated with NO and angiotensin II levels
Metalloproteinase-9 gene variants and risk for hypertension among ethnic Javanese
No full textBackground
Hypertension is associated with endothelial-dependent vasodilation disorders, due to reduced nitric oxide (NO) availability and excessive angiotensin II (ANG-II) activation. The objective of this study was to determine the association between matrix metallopeptidase 9 (MMP-9) gene polymorphism and hypertension in ethnic Javanese in the 40-80 year age group.
Methods
This was a case-control study on 50 PROLANIS patients of family doctors meeting the inclusion criteria and 50 controls without hypertension. Subjects were hypertensive patients with constant systolic arterial pressure of >140 mmHg and diastolic arterial pressure of >90 mmHg, confirmed in three successive measurements The observed parameters were degree of MMP-9 polymorphism, and NO and ANG-II levels. Matrix metallopeptidase 9 polymorphism was determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) using the SmaI restriction enzyme. MMP-9 polymorphisms were indicated by variation in band patterns. Degree of polymorphism in cases and controls were compared with NO and ANG-II levels in both groups. Data analysis was done using independent t-test.
Results
The heterozygous (3 band) to normal (2 band) MMP-9 genotype ratio was 3:1 in hypertensives, but balanced in controls. In hypertensives, heterozygous GA and homozygous AA genotype frequencies were respectively 3.198 and 1.548 times higher than that of the GG genotype (p=0.008 and p=0.726). There was a statistically significant differences of NO and Ang-II levels between cases and controls (p=0.000 and p=0.000; respectively).
Conclusion
Matrix metallopeptidase 9 gene polymorphisms in hypertensive ethnic Javanese are associated with NO and angiotensin II levels
Membangun Sistem Pendidikan Nasional, Mewujudkan Manusia Indonesia yang Unggul dan Berkarakter
No full textCOMMUNICATION Membangun Sistem Pendidikan Nasional, Mewujudkan Manusia Indonesia yang Unggul dan Berkarakter Abstrak Tulisan pendek ini merupakan pemikiran awal yang dihasilkan dari pandangan penulis yang bertujuan untuk memperbaiki kondisi pendidikan di negeri ini dari tingkat dasar sampai perguruan tinggi. Tulisan ini menekankan bahwa pendidikan merupakan sebuah sistem yang kompleks yang tidak dapat dipisahkan dari konteks politik, budaya dan ekonomi baik di tingkat lokal, nasional, regional, maupun internasional. Pendidikan sebagai suatu sistem kompleks, terdiri atas banyak komponen yang berinteraksi pada beberapa lapisan organisasi dan pada skala waktu yang berbeda. Kata Kunci: pendidikan, sistem kompleks Building a National Education System, Realize of indonesian people that Characterless and Excellence Abstract This short article is an initial thoughts resulting from the view of the author that aims to improve the state of education in this country from primary to university level. This paper emphasizes that education is a complex system that can not be separated from the political, cultural and economic at the local, national, regional, and international levels. Education as a complex system, consisting of many components that interact at multiple levels of the organization and at different time scales. Keywords: education, complex system
EFEK POLIMORFISME GENA GSTP-1 TERHADAP AKTIVITAS GLUTATION S-TRANSFERASE (GST) PADA INDIVIDU TERPAPAR LOGAM BERAT TIMBAL (Effect of GSTP-1 Gene Polymorphismson Glutation S- Transferase (GST) Activity in Heavy Metals Lead-Exposed Individual)
No full textABSTRAK
Gena GSTP-1 merupakan penghasil enzim glutation S- transferase (GST), yang berfungsi dalam proses detoksifikasi senyawa toksik di hati. Faktor keberadaan polimorfisme gena GSTP-1 akan menyebabkan penurunan ekspresi GST, sehingga proses detoksifikasi terhadap senyawa toksik akan terhambat. Kerentanan terhadap paparan senyawa toksik pada manusia akan meningkat apabila dijumpai polimorfisme gena. Salah satu senyawa toksik yang dapat menghambat aktivitas GST adalah timbal (Pb), terutama dalam bentuk tetra ethyl lead (TEL). Tujuan penelitian adalah untuk mengetahui pengaruh polimorfisme gena GSTP-1 terhadap aktivitas GST pada individu terpapar Pb, yang diwakili pekerja bengkel mobil. Faktor keberadaan polimorfisme gena individu ditentukan dengan metode PCR-RFLP dan enzim restriksi BsmA1. Parameter yang diukur adalah kadar Pb dan aktivitas GST. Analisis molekuler gena GSTP-1 dilakukan secara deskriptif. Data kadar Pb dan aktivitas GST dianalisis dengan uji t independent. Hasil analisis gena GSTP-1 dari 40 orang subyek kasus setelah dilakukan digesti dengan enzim BsmA1, ditemukan sebanyak 10 orang individu dengan polimorfisme Ile105Val gena GSTP 1 atau sekitar 25% dengan genotip Ile-Val, sedangkan 30 orang atau 75% ditemukan tanpa polimorfisme dengan genotip Ile-Ile. Pita DNA individu dengan polimorfisme terpotong menjadi 3 fragmen sepanjang 176, 91 dan 85 pp (mutan heterozygot), sedangkan tanpa polimorfisme terletak pada 176 bp. Subyek kasus dengan polimorfisme gena GSTP-1 memiliki kadar Pb lebih tinggi dan aktivitas GST lebih rendah dibandingkan individu non polimorfisme. Telah terbukti bahwa polimorfisme gena GSTP-1 menyebabkan penurunan ekspresi enzim GST. Pada individu terpapar Pb dengan polimorfisme gena GSTP-1 memiliki aktivitas GST lebih rendah dibandingkan individu tanpa polimorfisme.
ABSTRACT
GSTP-1 gene regulates the expression of gluthation S-transferase enzyme, which role in detoxification of toxicant on liver. If the polymorphisms gene is found in individual, the production of GST is decreased and the enzyme failed to eliminate toxicants. Lead is one of toxic agents that could inhibite GST activity especially tetra ethyl lead (TEL). The susceptibility to lead exposure will increase if the polymorphisms gene is found in population. The objective of this studies were to know the effect of gene GSTP-1 polymorphisms to GST activity on lead-exposed individual ie. autorepair workers. The genotype individu were analyzed by Polymerase Chain Reaction (PCR)-Restriction Fragment Length Polymorphisms with BsmA1 restriction enzyme followed by descriptived analyzed. Parameter recorded were blood lead and GST activity and data were analyzed by independent t-test. These result showed that 25% of 40 individual cases subject were detected by enzyme BsmA1 as polymorphisms individual of GSTP-1 gene, with Ile105Val genotype. As many as 75% were detected as non polymorphisms with Ile-Ile genotype. Three fragment DNA of polymorphisms individual of GSTP-1 is located on 176, 91 and 85 bp (heterozygote mutant) but non polymorphisms individual is only located on 176 bp. The Pb level of individual with polymorphisms GSTP-1 gene is higher than non polymorphisms individual but their GST activity was lower than non polymorphisms individual. It could be concluded that polymorphisms GSTP-1 gene could decrease the expression gene of GST enzyme and intoxication of lead-exposured could increased the decreasing of this activity
PENDIDIKAN KARAKTER DALAM KISAH ALQUR’AN DAN KEHIDUPAN EMPIRIK
No full textPendidikan di Indonesia dalam pandangan Asep Saefuddin dalam The Dancing Leader adalah pendidikan bernuansa pelatihan. Ada hal mendasar yang memperkuat argument dari pandangannya yaitu seharusnya pendidikan di Indonesia merupakan dasar bagi pembangunan bangsa bukan subsektor dari pembangunan itu sendiri. Ini berarti bahwa makna pendidikan telah direduksi dari yang seharusnya menjadi dasar pembangunan manusia Indonesia seutuhnya menjadi subsector pembangunan.( Asep: 2011: 197). Contoh produk pelatihan sangat banyak sekali misalnya; pengemudi yang lulus mendapat sim masih tetap hoby melanggar lalu lintas karena produk pelatihan yang dipentingkan adalah keterampilan tetapi mengabaikan bahaya kemanusiaan atas pelanggarannya itu. Apalagi yang hanya mendapat sim tembak tidak procedural. Demikian pula oknun petugas pajak sangat lihai menghitung berapa baesaran wajib pajak yang harus dibayar, namun penyimpangan atas pajak demikian merajarela. Karena pendidikan kita sangat bernuansa pelatihan dan hanya menguji kecerdasan seperti alat uji dengan memberlakukan UN, hasilnya hanya melatih siswa cerdas memilik soal-soal obyektif tes yang lemah membekali analisis problem. Dalam konteks di atas maka jika ada upaya-upaya mata pelajaran agama juga digiring untuk di UN kan hanya karena alasan agar mendapat perhatian pembelajarar dalam kegiatan proses. Ini pertanda makin menunjukkan kegagalan orientasi pendidikan agama yang harusnya membentuk moral dan karakter menjadi terampil menjawab soal-soal yang isinya menguji berbagai tentang; tentang shalat, tentang wudhu, tentang rasa hormat, tentang iman dll. Semuanya dibelajarkan dengan nihil nilai keberagamaan dan nihil moral, karena yang dikembangkan bukan potensi spiritual melainkan hanya wilayah kognitif semata. Kegagalan ini menurut hemat penulis jangan berjustifikasi atas nama UN sebagai solusi kegagalan, melainkan harus dievaluasi ulang, mulai dari cara membelajarkan, materi bahan ajar yang sudah terlalu tidak up to date untuk kepentingan kekinian baik kontennya maupun penjelasan dan contoh-contohnya termasuk juga pendekatan yang ditawarkan. Lihat satndar isi PAI baik di Sekolah maupun Madrasah
