1,721,140 research outputs found
Sinusoidal endothelial flogosis in mild to moderate rejection after ortopic liver transplantation(OLTx)
No full text
Epithelial-myoepithelial carcinoma of the parotid gland: Clinicopathological aspect, diagnosis and surgical consideration
No full textThe present paper describes the clinical and pathological features of epithelial-myoepithelial carcinoma (EMC) of the parotid gland. This rare tumor represents <1\% of all salivary gland tumors and arises most commonly in the parotid gland, but it has also been described in the submandibular gland, minor salivary glands and palate. EMC is considered to be a low-grade malignant tumor that may commonly recur locally after resection in 23-50\% of cases. The complex and varied morphological expression of this neoplasm has attracted numerous investigators, who have presented valuable but often contradictory data. After an in-depth analysis of the clinicopathological aspects of EMC, we speculate that adequate resection with negative soft-tissue margins is the minimum recommended and necessary therapy
Risks of combining immunosuppressive and biological treatments in inflammatory bowel disease - in reply
Full text linkWe thank Roblin and Phelip for their comment on a timely
issue. The recent report of the rare hepatosplenic T-cell lymphoma
(HSTCL) in young patients with CD treated with
both infliximab and azathioprine or steroids has rightly unleashed
a series of doubts regarding the optimal use of biological
agents in this and other conditions. How these observations
may directly relate to the design of our study—as
implied by Roblin and Phelip—is unclear though. While azathioprine
by itself has been linked to lymphoma development
including HSTCL, recent studies have shown that neither
infliximab nor methotrexate, which was used in our
study, alone or in combination in CD or in rheumatoid arthritis,
appear to be associated with an increased risk of
developing lymphomas. In addition, methotrexate alone has
never been associated thus far with HSTCL in CD
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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