132,049 research outputs found
Quietismi Revolutionem In Quietistis decimi quarti & huius seculi, Quam Praeses Jo. Andr. Schmidt ... observavit In lectionibus inauguralibus Ienae habitis, excerpere ex iisdem & ventilationi subiicere voluit Auth. Resp. Hieronymus Nieper Lüneburgensis : In Iuleo Maiori ad d. Octobr.
No full textQUIETISMI REVOLUTIONEM IN QUIETISTIS DECIMI QUARTI & HUIUS SECULI, QUAM PRAESES JO. ANDR. SCHMIDT ... OBSERVAVIT IN LECTIONIBUS INAUGURALIBUS IENAE HABITIS, EXCERPERE EX IISDEM & VENTILATIONI SUBIICERE VOLUIT AUTH. RESP. HIERONYMUS NIEPER LÜNEBURGENSIS : IN IULEO MAIORI AD D. [ ] OCTOBR.
Quietismi Revolutionem In Quietistis decimi quarti & huius seculi, Quam Praeses Jo. Andr. Schmidt ... observavit In lectionibus inauguralibus Ienae habitis, excerpere ex iisdem & ventilationi subiicere voluit Auth. Resp. Hieronymus Nieper Lüneburgensis : In Iuleo Maiori ad d. [ ] Octobr. (1)
Titelseite (1)
Widmung (2)
Beitrag (3)
Quietismi Revolutionem In Quietistis decimi quarti & huius seculi (5)
Widmungsgedichte (47
Two-dimensional convection with a self-lubricating, simple-damage rheology
No full textWe present 2-D simulations of convection in the Earth's mantle with temperature and damage-dependent viscosity in a basally heated system. The equation governing the temporal evolution of damage includes a source term for damage, a healing term and an advection term. A systematic study of the influence of the different damage terms on the convection pattern shows that: (1) at least four different convective regimes can be distinguished depending on the size of the damage source term and (2) self-lubricating behaviour is possible only if the advection term in the damage equation is small enough compared with the other terms. We also demonstrate, that good plate-like behaviour in terms of (a) focused low-viscosity bands (LVB), (b) homogeneous surface velocities within the plates and abrupt velocity jumps across the plate boundaries and (c) asymmetric subduction, can be obtained with this kind of rheology, although an increase in subduction asymmetry tends to make convection highly time-dependent
Experimental and theoretical evidences of hysteresis in passive mode-locked quantum dots lasers
No full textWe report experimental evidence of coexistence between passive mode-locking (ML) solutions and laser off state in a monolithic two sections InAs/InGaAs Quantum Dot (QD) semiconductor laser. The considered device has a 0.4 mm long straight absorber and a 2.380 mm long active region characterized by a 2° full taper angle. The active side facet is as cleaved, while the absorber side facet is high reflection coated
A critical look at different nursing realities
No full textBrandenburg H, Hämel K, Auth D. Ein kritischer Blick auf verschiedene Pflegerealitäten. In: Abstracts des Gerontologie und Geriatrie Kongresses 2022 „Altern im Spannungsfeld von Resilienz und Vulnerabilität“. Zeitschrift für Gerontologie und Geriatrie . Vol 55. Heidelberg: Springer ; 2022: 105
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays
No full textBackground: Alternative mRNA processing mechanisms lead to multiple transcripts (i.e. splice isoforms) of a given gene
which may have distinct biological functions. Microarrays like Affymetrix GeneChips measure mRNA expression of genes
using sets of nucleotide probes. Until recently probe sets were not designed for transcript specificity. Nevertheless, the reanalysis of established microarray data using newly defined transcript-specific probe sets may provide information about expression levels of specific transcripts.
Methodology/Principal Findings: In the present study alignment of probe sequences of the Affymetrix microarray HGU133A with Ensembl transcript sequences was performed to define transcript-specific probe sets. Out of a total of 247,965 perfect match probes, 95,008 were designated ‘‘transcript-specific’’, i.e. showing complete sequence alignment, no crosshybridization, and transcript-, not only gene-specificity. These probes were grouped into 7,941 transcript-specific probe sets and 15,619 gene-specific probe sets, respectively. The former were used to differentiate 445 alternative transcripts of 215
genes. For selected transcripts, predicted by this analysis to be differentially expressed in the human kidney, confirmatory real-time RT-PCR experiments were performed. First, the expression of two specific transcripts of the genes PPM1A (PP2CA_HUMAN and P35813) and PLG (PLMN_HUMAN and Q5TEH5) in human kidneys was determined by the transcriptspecific array analysis and confirmed by real-time RT-PCR. Secondly, disease-specific differential expression of single transcripts of PLG and ABCA1 (ABCA1_HUMAN and Q5VYS0_HUMAN) was computed from the available array data sets and confirmed by transcript-specific real-time RT-PCR.
Conclusions: Transcript-specific analysis of microarray experiments can be employed to study gene-regulation on the
transcript level using conventional microarray data. In this study, predictions based on sufficient probe set size and foldchange are confirmed by independent mean
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