180 research outputs found
The Countermanding Order, 1916
No full text“The Countermanding Order, 1916”, de Moya Cannon, traduzido por Gisele Wolkoff. Retirado do livro Donegal Tarantella, Carcanet, 2019. Reproduzido com a permissão da autora e da editora. “The Countermanding Order, 1916” by Moya Cannon. From Donegal Tarantella. Carcanet, 2019. Reproduced by kind permission of the author and the publisher
The Impact of the pH on the Concentration of the Released Ogremorphin-Mimic Dye from Double-Network Hydrogels for Glioblastoma Localized Treatment
No full textGlioblastoma (GBM), a highly aggressive brain cancer, poses significant treatment challenges due to its complex microenvironment and low therapeutic efficacy of current approaches. Localized drug delivery systems hold promise for improving therapeutic outcomes. This study investigated the release of an Ogremorphin (OGM)-mimic dye from a double-network hydrogel (DNH) designed for GBM therapy, hypothesizing that the hydrogel would have a steady release of the mimic drug at a lower pH. A polyacrylamide alginate DNH was synthesized, and its swelling behavior, drug-loading efficiency, and release dynamics were evaluated. The hydrogel’s swelling degree was calculated after 72 hours of immersion in distilled water. Drug loading efficiency was determined by UV-Vis spectroscopy, measuring the residual concentration of a fluorescein solution. Dye release was assessed under various pH conditions from 4-8, simulating the tumor microenvironment (TME), with cumulative release profiles analyzed over 228 hours. The hydrogel exhibited a swelling degree of 135.8% and a drug loading efficiency of 87.4%. Drug release was pH-dependent, with minimal release at acidic pH (4 and 5) due to a compact polymer network and an increased release at alkaline pH 8, driven by network swelling. Statistical results from the one-way ANOVA test showed that F(4, 85) = 17.72, p \u3c .001. A post-hoc Tukey test showed a significant difference between the different pH levels. Optimized formulations at pH 4- 6 could minimize burst release, sustain therapeutic levels, and improve patient outcomes. These findings demonstrated the hydrogel’s pH-responsive properties made it a strong candidate for GBM therapy
Innovative Temperature-Responsive Fluorescent Hydrogel for Smart Windows and Advanced Environmental Sensing
No full textThe presented study described the synthesis, characterization, and temperature-responsive fluorescence behaviour of a dual-chromophore double-network hydrogel (DNH) that incorporates poly(N-isopropylacrylamide) (PNIPAM) covalently crosslinked with fluorescein diacrylate (FL-DA), as a primary network, followed by the formation of a secondary poly(2-acrylamido-2-methylpropanesulphonic acid) (PAMPS) network incorporating fluorene diacrylate (FR-DA) as a second covalently-integrated chromophore. The thermoresponsive PNIPAM/PAMPS hydrogel had a dual-wavelength signaling and mechanically robust structure that could be used for environmental sensing, innovative thermal coatings, and smart surface applications. The temperature-dependent fluorescence spectra were recorded from 5 °C to 60 °C and exhibited two emission bands characteristic of the two chromophores. The increase in temperature produced a decrease in band intensity and a red shift. The short-wave emission characteristic of FR-DA exhibited wavelength shifts of 9 nm and 8 nm, corresponding to overall increases of 2.91% and 2.49%, respectively. FL-DA exhibited a long-wave emission peak that shifted to red by 14 nm, from 511 to 525 nm, corresponding to a 2.74% increase in wavelength over the 5 to 60 OC temperature range. The one-way ANOVA showed F(11, 3600) = 2.20, p \u3c 0.012. A post hoc Tukey test confirmed that the control condition (25 °C) differed across all temperature groups. The increase in temperature altered the degree of polymer hydration, increased chain mobility, and altered chromophore orientation, leading to enhanced non-radiative relaxation and spectral changes. The PNIPAM network undergoes a coil-to-globule transition, which produces a pronounced inflection in the overall fluorescence behavior
Cisza jako symbol śmierci w refleksji Gisele Brelet i Tōru Takemitsu
No full textThe link between silence and death has been a recurring theme of human thought and can often be found in reflections on music. Among many attempts to approach this problem, the author of this paper focuses on those done by Gisele Brelet and Tōru Takemitsu. The “faithful companion” of music which “perpetually is born, dies and is born again” – this is one of the ways in which French musicologist describes silence. “For a human being, there is always the duality of life and death. Music as an art form always has to connect vehemently with both” – notices Japanese composer, who in another statement combines silence with “the dark world of death”. Interestingly, both Brelet and Takemitsu arrive at the conclusion that such connotations may well be the source of the fear of silence that affects some composers or performers. Despite different contexts, some analogies to their thought – like connecting silence with nothingness and loneliness – may be also found in the Canadian composer Raymond Murray Schafer’s writings, presented fragmentarily in the last subsection. The differences in the notion of the problem between the authors are, moreover, discussed in this paper.Związek pomiędzy ciszą i śmiercią to wciąż powracający motyw w ludzkiej myśli. Często znajduje on swoje odzwierciedlenie w muzyce. Spośród licznych prób zmierzenia się z tą kwestią autor niniejszego artykułu skoncentrował się na tych podjętych przez Gisele Brelet i Tōru Takemitsu. „Wierna towarzyszka” muzyki, „stale rodząca się, umierająca i odradzająca się na nowo” – oto jeden ze sposobów, w jaki ciszę opisuje francuska muzykolog. „Dla człowieka zawsze będzie istniał dualizm życia i śmierci. Muzyka jako forma sztuki musi się łączyć z całą żarliwością z każdym z tych elementów” – zauważa japoński kompozytor, który w innej wypowiedzi łączy ciszę z „mroczną krainą śmierci”. Co ciekawe, zarówno Brelet, jak i Takemitsu dochodzą do wniosku, że tego rodzaju powiązania mogą stać się źródłem strachu przed ciszą, wpływającego na kompozytorów bądź wykonawców. Pomimo odmiennych kontekstów pewne analogie do ich poglądów – na przykład łączenie ciszy z nicością i samotnością – można odnaleźć w pismach kanadyjskiego kompozytora Raymonda Murraya Schafera. Zostały one pokrótce omówione w ostatnim podrozdziale. W artykule zaprezentowano także różnice w spojrzeniu autorów na podjęty problem
Contribution to the Analysis of the Construction of Identities Based on Senegalese Migrants’ Belonging to a Brotherhood in Argentina
No full textEl presente artículo propone analizar las configuraciones identitarias de los migrantes senegaleses residentes en la Ciudad Autónoma de Buenos Aires a partir de su pertenencia a las cofradías, entendidas como comunidades de base religiosa que tienen cierto alcance en numerosos aspectos de su vida cotidiana. Para ello, y valiéndose de entrevistas en profundidad y de escritos acerca del Islam y su expansión en el territorio senegalés, pero sobre todo de la conformación y estructuración con base en las cofradías, se lleva a cabo una reflexión en torno a su efecto en la (re)configuración identitaria comunitaria de su asentamiento en Argentina y los procesos de resignificación.This article analyzes the identity configuration of Senegalese migrants residing in the city of Buenos Aires, based on their belonging to brotherhoods, understood as religious base communities that have a certain influence in many aspects of their daily lives. Using in-depth interviews and writings about Islam and its expansion in Senegal, but above all the creation and structuring of their communities based on brotherhoods, the author reflects on their effect in the (re)configuration of their community identity in their Argentinean settlements and the processes of re-signification involved.Fil: Kleidermacher, Gisele Paola. Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Investigaciones "Gino Germani"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
Emoção e aprendizagem de temas ambientais com integração de tecnologias na experiência de estudantes surdos.
No full textThe research discusses the learning of deaf people in relation to environmental issues. The author analyzes the experiences of students in relation to learning and contact with an environmental theme. The methodology used is qualitative, in the form of research and involved the development of workshops on environmental themes, with emphasis on the concept of semiarid. The analysis is considered as one of the strategies of control of change of conduits in the sessions of interaction between participants that construct the environmental questions. The main components of data collection were: on-board analysis, filming and photographs, conversation wheels, experience analysis, observation and analysis of the productions made in the workshops. We were able to distinguish the actions of people at the service of concepts and in the production directives on environmental policies. Truth and joy were emerging in doing,
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transforming experience into a journey through fear and mistrust in their perceptual conditions due to deafness. As a result of research, it is also possible to emphasize the need to put into practice building processes, materials, supports for learning of people who are not and do not exercise during the learning process in their training exercises and their knowledge and life pathsA pesquisa discute sobre a aprendizagem das pessoas com surdez em relação aos temas ambientais. A autora analisa experiências de estudantes surdos em relação a aprendizagem e ao contato com a temática ambiental. A metodologia empregada é qualitativa, na forma da pesquisa intervenção e envolve desenvolvimento de oficinas sobre temas ambientais, com ênfase no conceito de semiárido. A análise considera as pistas do método da cartografia para acompanhar mudanças nas condutas, nas emoções dos participantes nas interações que constroem sobre temas ambientais. Os instrumentos principais de coleta de materiais para a análise foram: diário de bordo do pesquisador, filmagens e fotografias, rodas de conversa no transcurso da experiência, observação e análise das produções feitas nas oficinas. Pudemos distinguir os movimentos nas emoções das pessoas surdas ao se apropriarem de conceitos e nas ações diretas de produção sobre temáticas ambientais. A confiança e a alegria foram emergindo no fazer, transformando experiência inicial marcada pelo temor do não saber e pela desconfiança em suas condições perceptivas devido à surdez. Como resultado de pesquisa, podemos ainda ressaltar a necessidade de seguirmos investindo na construção de metodologias, materiais, suportes para que as aprendizagens de pessoas surdas e não surdas possam acontecer de modo a estarem juntas nos percursos de formação e avançarem em seus conhecimentos e percursos de vidaTrabalho não financiado por agência de fomento, ou autofinanciad
A historical review of the Carrie Steele-Pitts home, incorporated in Fulton county, Georgia, 1979
No full textThis study is a historical review of the Carrie Steele-Pitts Home, Inc., a foster care facility. The Carrie Steele-Pitts Home has been in existence since 1886. Its main purpose was and still is to care for neglected boys and girls. The purpose of this study demonstrates the fact that the Black community has played a very important role in the development of young people through the service of foster care
From the Sound of the People to the Echoes of the Past: The Versions of La pasión según Trelew, by Tomás Eloy Martínez (1973-2009)
No full textLa pasión según Trelew occupies a paradoxical place in the work of Tomás Eloy Martínez. On the one hand, it is the book that changed the author's life, as he himself has described it, and the only one whose writing process went through practically all the stages of his literary work: it originally appeared in 1973 and was re-edited in 1997 and 2009, each time with textual variations introduced by the author. On the other hand, the book seems to constitute the crystallization of a concept of writing, based on trust in absolutes and on the militant confrontation between the true and the false, from which the writer sought to distance himself in later on his career. In this article, we propose to analyze the way in which this displacement is reflected in the different versions of the book. We will see that the versions of 1997 and 2009 tend to dilute the confrontation between truth and falsehood that initially shaped the account of the events that took place in Trelew in 1972. Likewise, the rewritings detract from the People's role as a collective subject that provided the basis for the confrontation between truth and lie that organized the text.La pasión según Trelew ocupa un lugar paradójico en la obra de Tomás Eloy Martínez. Por un lado, ese llibro que le cambió la vida al autor, según él mismo lo ha descrito, y el único cuyo proceso de escritura atravesó prácticamente todas las etapas de su producción literaria: apareció originalmente en 1973 y fue reeditado en 1997 y 2009,cada vez con variaciones textuales introducidas por el autor. Por otro lado, el libro parece constituir la cristalización de una concepción de la escritura, sustentada en la confianza en los absolutos y en la confrontación militante entre lo verdadero y lo falso, de la que el escritor buscó distanciarse en momentos ulteriores de su trayectoria. En este artículo nos proponemos analizar el modo en que ese desplazamiento se inscribe en las distintas versiones del libro. Veremos que las versiones de 1997 y 2009 tienden a diluir la confrontación entre verdad y mentira que inicialmente daba forma al relato de los hechos ocurridos en Trelew en 1972. Asimismo, las reescrituras le restan protagonismo al Pueblo como sujeto colectivo que proveía fundamento a la confrontación entre verdad y mentira organizadora del texto.Fil: García, Victoria Gisele. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filología y Literatura Hispánica "Dr. Amado Alonso"; Argentin
Language policies from the semiperiphery: an analysis of author guidelines in Brazilian English-medium journals
No full textThe recent rise in the number of English-medium journals in non-Anglophone
countries stems from the hegemony of English in global scholarly
communication, and language requirements outlined by such journals to authors
offer a valuable yet often overlooked source of information in terms of
underlying values and assumptions concerning knowledge production and
circulation. Drawing on the notion of “semiperiphery” to refer to Brazil’s
current standing within global scientific publishing, this exploratory study
focuses on author guidelines of Brazilian English-medium journals indexed in
the SciELO database to map language requirements established for manuscript
submission and to assess, from a discursive perspective, whether they reinforce
or disprove dominant ideologies regarding academic publishing, knowledge
construction and dissemination, and the status of English as the academic lingua
franca. The research data included 98 journal guidelines sections from seven
subject areas, and results suggest that journals across the disciplinary spectrum
endorse the primacy of (native speaker) English in knowledge dissemination,
which calls for a critique of scientific monolingualism on the part of research
policymakers, in Brazil and elsewhereO aumento recente no número de periódicos que publicam exclusivamente em
inglês em países não anglófonos alinha-se com a hegemonia do inglês no âmbito
da comunicação acadêmica global, e as exigências de linguagem feitas por tais
periódicos aos autores surgem como fonte de dados ao mesmo tempo valiosa e
pouco explorada no que tange aos valores e às concepções que subjazem à
produção e circulação de conhecimento. Pautado no conceito de “semiperiferia”
para definir a atual posição do Brasil no contexto internacional de edição
científica, este estudo exploratório analisa a seção “diretrizes para autores” de
periódicos científicos brasileiros indexados no SciELO que publicam somente
em inglês. Objetiva-se, com isso, mapear as exigências de linguagem atribuídas ao
processo de submissão de manuscritos e avaliar, sob uma perspectiva discursiva,
se estas reforçam ou contradizem ideologias dominantes concernentes à edição
acadêmica, à construção e disseminação de conhecimento e ao estatuto do inglês
como língua franca da ciência. Os dados incluem diretrizes de 98 periódicos
vinculados a sete grandes áreas do conhecimento, e os resultados indicam uma
tendência transdisciplinar de endossar a primazia do inglês (nativo) na circulação
de conhecimento, tendência essa que demanda uma crítica do monolinguismo
científico por parte de agentes decisórios e formuladores de políticas de
incentivo à pesquisa, tanto no Brasil quanto em outros paíse
La «simple présentation des faits»: Rodolfo Walsh et les débuts de la littérature testimoniale en Amérique latine
No full textLoin de renvoyer à une origine univoque, la littérature testimoniale a connu maints débuts au cours de l’histoire culturelle latino-américaine. Nous nous proposons ici de nous pencher sur l’un de ses débuts, en partant de l’œuvre de l’écrivain argentin Rodolfo Walsh, dans un contexte où le témoignage prenait un véritable essor dans le champ culturel latino-américain, jusqu’à atteindre son institutionnalisation en tant que genre littéraire par la Casa de las Américas (en français, « Maison des Amériques ») au début des années 70. La distinction entre généricité auctoriale et lectoriale signalée par Jean-Marie Schaeffer nous permet d’ailleurs de rappeler que le fait de considérer Walsh comme un auteur pionner du témoignage en Amérique latine (tel que l’ont fait les intellectuels ayant étayé l’institutionnalisation du genre) est apparu de manière rétroactive en appliquant ladite catégorie à Opération massacre (1957), un texte qui, d’un point de vue auctorial, n’était donc pas à strictement parler testimonial. Nous montrerons également que la prose factuelle de Walsh, que l’auteur lui-même a cherché à englober sous le nom de « témoignage », constitue en soi un corpus à la fois hétérogène génériquement parlant et dynamique du point de vue de l’identité classificatrice qui lui a été attribuée a posteriori. C’est ainsi que, dès l’institutionnalisation du genre dans les années 70, l’hétérogénéité et le dynamisme caractérisèrent l’histoire de la littérature testimoniale d’Amérique latine.Far from relating to a univocal origin, testimonial literature has begun several times in the cultural history of Latin America. In this work, we approach one of its beginnings, basing on a study of the Argentine writer Rodolfo Walsh’s work, in the context of the rise of testimony in the Latin American cultural field, which led to its institutionalization as a literary genre in Casa de the Americas, in the early 1970s. We rely on the distinction between authorial and lectorial genericity pointed out by Jean-Marie Schaeffer, to argue that Walsh’s weight as a pioneering author of Latin American testimony, stressed by the intellectuals who promoted the institutionalization of the genre, arose from a retroactive application of such category to Operation Massacre (1957), a text that, from an authorial point of view, was not strictly testimonial. We further argue that Walsh’s factual narrative, which the author himself sought to define as « testimony », strictly speaking constitutes a heterogeneous corpus regarding its generic features, and dynamic from the point of view of the classificatory identity that is subsequently was attributed to it. More generally, as from the institutionalization of gender in the 1970s, heterogeneity and dynamism signify the history of Latin American testimonial literature.Fil: García, Victoria Gisele. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filología y Literatura Hispánica "Dr. Amado Alonso"; Argentin
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