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Editorial. The Faces of Mania. The Legacy of Athanasios Koukopoulos
Full text linkThe concept of “Mania” is intimately linked to the evolution of psychiatry itself. The Legacy of Athanasios Koukopoulos
Transitions: Athanasios Koukopoulos [AθανάσιΟς κΟυκόπΟυλΟς], M.D. (1931–2013)
Full text linkAthanasios Koukopoulos was born in Chaeronea, a village in the district of Boeotia in central Greece, on 23 November 1931 as the son of Konstantinos and Maria Koukopoulos. His father hoped that he would remain at home to manage the land they owned, but Athanasios preferred to study. His energetic and supportive mother fought for his education. At the end of World War II, following years of exposure to violence and privation, his family moved to Athens just before the Greek civil war of 1946 to 1949. In Athens, Koukopoulos continued his education while playing professional basketball with the prestigious Panatinaikos Sports Club of Athens, which later on presented him with the Golden Clover award. In 1951, he moved to Italy despite remaining hard feelings in Greece following the recent Greco-Italian war of 1940 to 1941 and the subsequent Balkan campaign of the Axis powers in World War II
Athanasios koukopoulos’ psychiatry: The primacy of mania and the limits of antidepressants
Full text link© 2017 Bentham Science Publishers. Background: Athanasios Koukopoulos provided a radical model for understanding depressive and manic conditions. Objective: To review, explain, and analyze Koukopoulos’ concept of the primacy of mania, with special attention to the role of antidepressants. Method: A conceptual review of Koukopoulos’ writings and lectures on this topic is given._ Results: Koukopoulos held that depressive states are caused by manic states; the former do not occur without the latter. The most common scenario of the inseparability of depressive and manic symptoms occurs in mixed states, which we estimate to represent about one-half of all depressive episodes in all patients (not just bipolar illness). In a review of the empirical evidence for this topic, we conclude that empirical evidence exists to support the primary of mania thesis in almost 80% of depressed patients. Since antidepressants worsen mania, they would be expected to worsen depression as well in this model.
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Koukopoulos׳ diagnostic criteria for mixed depression: A validation study
Full text linkArtículo de publicación ISIBackground
Mixed depression (MxD) is one subtype of depressive experiences within the depressive spectrum. MxD definition is debated among experts. Koukopoulos׳ proposed diagnostic criteria focused primarily on psychic agitation, marked irritability, and intense mood lability as markers of a mixed depressive episode. The present study validates Koukopoulos׳ criteria as diagnostic for MxD.
Methods
A sample of 435 patients from the International Mood Network (IMN), multi-center, international network of sites, and the Centro LucioBini of Rome was analyzed. Koukopoulos׳ criteria were assessed in all patients.
Results
The most prevalent MxD criteria were “absence of psychomotor retardation” (84%), “mood lability or marked reactivity” (78%), and “psychic agitation or inner tension” (75%). Multivariable predictors of a MxD (+) diagnosis were: higher current CGI (OR=1.23, 95% CI 1.23, 2.84), lower rates of previous bipolar type I diagnosis (OR=0.54, 95% CI −3.28, −0.13), mixed symptoms on the index episode (OR=10.02, 95% CI 2.32, 24.12), rapid cycling course (OR=2.6 95% CI 1.45, 3.56), past substance abuse (OR=3.02, 95% CI 2.01, 5.67) and lower education status (OR=0.44, 95% CI −3.23, −0.98). This model showed a sensitivity of 76.4%, specificity of 86.3%, negative predictive value of 75%, and positive predictive value of 86%.
Limitations
An external validation of these criteria in an independent sample is warranted.
Conclusion
A broad definition of mixed depression was internally validated with multiple diagnostic validators and was sensitively and specifically predicted. Contrary to DSM-5, Koukopoulos׳ broad criteria include agitation, irritability and mood lability as core features
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Transitions: Athanasios Koukopoulos [AθανάσιΟς κΟυκόπΟυλΟς], M.D. (1931–2013)
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Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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Transitions: Athanasios Koukopoulos [AθανάσιΟς κΟυκόπΟυλΟς], M.D. (1931–2013)
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