39 research outputs found
HERMENEUTIKA OTENTISITAS HADIS M. MUSTOFA AZAMI
No full textThis article discusses Azami criticism to Ignaz Gholziher and Joseph Schacht. The author tries to integrate the relations of hermeneutics as a solution to solve the issues of Hadith authenticity, and its interconnected to psychology, that Azami position when criticizing the Orientalists, Joseph Schacht, based on the flow of his thought of isnaad. Then in reviewing hermeneutics, in general there are three dominant element is the relationship between (author), Text (text) and readers (reader). So the results of this analysis, the author is orientalist, Joseph Schacht Ignaz Goldziher. The Text is orientalist books, thoughts, opinions or their theories, in this case Joseph Schacht. The reader is referred Azami. The discovery of the authors that position Azami criticism included are the internal and external criticism, namely external criticism Azami focus lies in criticism of the Orientalists, he criticized Joseph from isnaad. And internal criticism, plays on historiography, he criticized the use of sciences related to hadith, such as ‘Ilm Tadwin al-Hadith, ‘Ilm Rijal al-Hadith, ‘Ilm Jarh wa ta\u27dil, Ulum al-Hadith, ‘Ilm al-Fiqh.Dalam tulisan ini dikaji Kritik Azami terhadap kedua orientalis yaitu Ignaz Gholziher dan Joseph Schacht. Penulis mencoba mengintegrasikan bagaimana hubungan hermeneutika sebagai solusi untuk memecahkan isu-isu otentisitas Hadis, dan aplikasi interkoneksinya seperti ilmu psikologi, bahwa posisi Azami ketika mengkritik terhadap orientalis yaitu Joseph, ia melihat berdasarkan alur pemikiran isnadnya. Kemudian dalam mengkaji hermeneutika, secara garis besar ada tiga unsur yang dominan yaitu hubungan antara (author), teks (text) dan pembaca (reader). Maka hasil dari analisis ini, author adalah orientalis yaitu Joseph Schacht, Ignaz Goldziher yang mana textnya adalah buku-buku orientalis, pemikiran, pendapat atau teori orientalis dalam hal ini Joseph Schacht, yang dimaksud reader adalah Azami. Penemuan penulis bahwa posisi kritik Azami termasuk berada dalam kritik internal dan eksternal, yaitu fokus kritik eksternal Azami terletak pada kritik terhadap orientalis, ia mengkritik Joseph dari isnadnya. Dan kritik internal, berposisi pada historiografi, ia mengkritik menggunakan ilmu-ilmu yang berkaitan dengan hadis, seperti ilmu tadwin al-hadis, ilmu rijalul hadis, ilmu jar wata’dil, Ilmu Hadis, ilmu Fiqih
Kajian Hadis Mustafa Azami Sebagai Kerja Hermeneutika (Analisis Kajian Sanad dan Matan Hadis dalam Studies in Hadith Methodologi and Literature Karya Mustafa Azami)
No full textyang tak terelakkan dalam kajian hadis. Dari sini penting disadari bahwa hermeneutika bukan hal baru, apalagi “sesuatu” yang berbahaya bagi kajian Hadis. Istilah ini memang bukan dari pemikir Islam. Namun secara subtansi, hermeneutika sebagai kerja kritis atas hadis (sanad dan matan) telah melekat di kalangan muslim klasik dan modern-kontemporer. Tulisan ini ingin membuktikan bahwa Azami sekalipun, yang dikenal ‘anti’ barat, secara subtansi melakukan kerja hermeneutika. Metode kajian hadis Azami, baik sanad maupun matan akan ditarik dalam diskusi hermeneutika hadis, yang dalam hal ini penulis akan menggunakan tiga unsur dasar dalam wacana hermeneutika, yakni author (perawi), teks (hadis) dan reader (Azami). Artikel ini akan menjawan tentag bagaimana dan sejauhmana metode pemikiran hadis Mustafa Azami dapat diposisikan sebagai kerja hermeneutika, dalam hal ini sebagai kajian kritis atas sanad dan matan hadis? Hasil kajian menunjukkan bahwa Azami dalam kerja hermeneutika-nya senantiasa mengungkap diskusi keorisinalitas perawi (sanad) dan kerasionalitas matan dengan melakukan metode perbandingan. Argumen nalar digunakan dalam konteks menelusuri seputar fakta perawi, dan menentukan masuk akal atau tidaknya kandungan matan hadi
Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro.
No full textWe previously demonstrated gradual loss of epiblast during diapause in embryos lacking components of the LIF/IL6 receptor. Here, we explore the requirement for the downstream signalling transducer andactivator of transcription STAT3 and its target, TFCP2L1, in maintenance of naïve pluripotency. Unlike conventional markers, such as NANOG, which remains high in epiblast until implantation, both STAT3 and TFCP2L1 proteins decline during blastocyst expansion, but intensify in the embryonic region after induction of diapause, as observed visually and confirmed using our image-analysis pipeline, consistent with our previous transcriptional expression data. Embryos lacking STAT3 or TFCP2L1 underwent catastrophic loss of most of the inner cell mass during the first few days of diapause, indicating involvement of signals in addition to LIF/IL6 for sustaining naïve pluripotency in vivo. By blocking MEK/ERK signalling from the morula stage, we could derive embryonic stem cells with high efficiency from STAT3 null embryos, but not those lacking TFCP2L1, suggesting a hitherto unknown additional role for this essential STAT3 target in transition from embryo to embryonic stem cells in vitro. This article has an associated First Person interview with the first author of the paper
A rare case of coexistence of Wegener’s granulomatosis and pulmonary tuberculosis with subsequent development of thrombosis of the cerebral veins
No full textAbstract Background Granulomatosis with polyangiitis (GPA), also known as Wegener’s granulomatosis, is an idiopathic systemic disease typically affecting the lungs, although other organs may also be involved. Case presentation A 28-year-old male was admitted to Baqiyatallah university hospital in Teheran (Iran) after a 3-week history of fever and productive cough. The patient gradually developed fatigue, arthralgia, hematuria, nausea, vomiting, dyspnea, hemoptysis, weight loss, oliguria and then anuria. Chest-X-ray (CXR) and computerized tomography scan revealed cavitating nodular opacities in the right lung lobe. Furthermore, plasma creatinine increased from 2.2 to 4 mg/dl in a few days. Histopathological examination of kidney biopsy revealed peri-glomerular and peri-vascular inflammation, degeneration and necrosis of the tubular epithelial lining, red blood cell casts, distorted glomerular structure, fibrin thrombi, segmental breaks of the glomerular basal membrane, disruption of Bowman's capsular membrane and crescent formation of the affected glomeruli. An abnormal CXR, an abnormal urinary sediment and a typical kidney histology were used as criteria to diagnose glomerulonefritis with poliangiitis (GPA). Bronchoalveolar lavage smear and PCR turned out positive for mycobacterium tuberculosis. After 3 months of treatment for (GPA) and tuberculosis the patient developed headache and seizure. Cerebral Magnetic Resonance Venography revealed cerebral venous thrombosis of the sinus transverse and sigmoid. Conclusions Tuberculosis may coexist with GPA, as it occurred in our patient. Since a crescentic glomerulonephritis can progress to renal failure, clinicians should always be aware of potential multiple conditions when considering differential diagnoses
Pathologic findings of acantholytic squamous cell carcinoma coexisting with cutaneous cryptococcosis in a Houbara bustard (Chlamydotis undulata)
No full textA 2-year-old Asian Houbara bustard was presented with a solitary well-defined, firm cutaneous mass on the hock region. Grossly, the mass protruded from the surface was located on the hairless and unpigmented areas of the right hock joint with ulceration and dried hemorrhagic foci. On microscopic examination, ulceration, hemorrhage, as well as hyperkeratosis were observed. Large round, oval to polygonal neoplastic cells extended into the dermis were arranged to form cords, trabeculae, islands or glandularlike structures without keratin pearls. These pseudoglandular structures were composed of pseudolumina containing acantholytic and detached tumor cells. Necrosis of the neoplastic cells was accompanied by infiltration of inflammatory cells particularly heterophils. Unlike pleomorphic tumor cells, mitosis count was almost frequent. No evidence of other abnormalities and tumor metastasis was found. These gross and microscopic features appeared to be suggestive of a rare histologic variant of squamous cell carcinoma (SCC
Child Marriage in Afghanistan: the costs and consequences that we don't know
No full textThis article explores the issue of child marriage in Afghanistan, emphasizing its impact on maternal health and overall development. It discusses the knowledge gap regarding community awareness and government action. The author conducts a literature search, critiquing two research papers for their methodology and findings.
The conclusion highlights the limited value of existing research, with the need for more robust studies and policy development. Afghanistan lacks specific legislation defining the age of marriage, which remains a concern
Mixed coordinate Node link Visualization for Co_authorship Hypergraph Networks
No full textWe present an algorithmic technique for visualizing the co-authorship
networks and other networks modeled with hypergraphs (set systems). As more
than two researchers can co-author a paper, a direct representation of the
interaction of researchers through their joint works cannot be adequately
modeled with direct links between the author-nodes. A hypergraph representation
of a co-authorship network treats researchers/authors as nodes and papers as
hyperedges (sets of authors). The visualization algorithm that we propose is
based on one of the well-studied approaches representing both authors and
papers as nodes of different classes. Our approach resembles some known ones
like anchored maps but introduces some special techniques for optimizing the
vertex positioning. The algorithm involves both continuous (force-directed)
optimization and discrete optimization for determining the node coordinates.
Moreover, one of the novelties of this work is classifying nodes and links
using different colors. This usage has a meaningful purpose that helps the
viewer to obtain valuable information from the visualization and increases the
readability of the layout. The algorithm is tuned to enable the viewer to
answer questions specific to co-authorship network studies.Comment: 10 pages, 3 figures, 1 tabl
Sleep Disorders in Methadone Maintenance Treatment Volunteers and Opium-dependent Patients
No full textBackground: The relationship between substance use and sleep is bidirectional. Substance use directly causes sleep disturbances, and sleep problems are a critical factor in substance-use relapse. Methods: This study evaluated sleep disorders in 65 methadone maintenance treatment (MMT) patients, and 61 opium-dependent patients who did not receive any treatment between September 2011 and July 2012 in Kermanshah, Iran. Both groups filled out the Pittsburgh Sleep Quality Index (PSQI) and Global Sleep Assessment Questionnaire (GSAQ).Findings: Sleep disorders were remarkably similar in both groups: 78.5% of MMT patients and 87.7% of opium-dependent patients suffered from sleep problems. Sleep disorders in the opium-dependent group were remarkably higher and more prominent.Conclusion: Compared to opium, MMT does not have as many negative effects on sleep and is more effective in mitigating sleep problems
The Effects of Environmental Modifications on Improving the Sleep Quality of the Elderly Hospitalized in the Cardiac Care Unit
No full textBackground: Sleep deprivation is a common problem among the elderly in the cardiac care unit (CCU). Objectives: The present study aimed to determine the effects of environmental modifications on sleep quality improvement in these people. Methods: The study population included 60 elderly patients whose sleep quality was assessed by the Pittsburgh Sleep Quality Index with even domains. The environmental factors that can disturb sleep quality were determined via a questionnaire, including 13 questions on a 5-point Likert scale. Descriptive and inferential statistical analyses were performed in SPSS 22 software via indepen-dent sample student t-test and chi-square. Results: After environmental modifications, the total sleep quality scores changed from 11.8 to 5.96, indicating sleep quality im-provement. Before executing the environmental modifications, there were no significant correlations between sleep quality scores and demographic variables (sex, age, marital status, and economic status). However, after the modifications, there was a significant relationship between sleep quality and economic status (P = 0.024). Conclusions: Environmental factors can affect sleep quality in the elderly hospitalized in CCU. Therefore, it is possible to improve sleep quality in these individuals by modulating environmental conditions. © 2021, Author(s)
