65 research outputs found
Autoimmune Thyroid Disease and Sjögren Disease: Organ-Specific Disease Triggered by Systemic Autoimmunity?
No full textBackground and Objectives: Autoimmune thyroid diseases are more prevalent in patients diagnosed with Sjögren disease (SD) than in the general population. SD and autoimmune thyroid diseases are two distinct yet interrelated autoimmune disorders. The objective of this study was to determine the frequency of autoimmune thyroiditis (AT), autoantibody relationships, and clinical features in patients with SD. Materials and Methods: The study included 525 patients. A retrospective evaluation was conducted on the demographic data, biochemical and serological tests, and pathological data of the patients. An anti-nuclear antibody (ANA) test was performed using the indirect immunofluorescence (IIF) method using HEp-2 (HEp-2000) cells as substrate. The Schirmer test and minor salivary gland biopsy were conducted on all patients. Results: AT was detected in 167 (31.8%) of 525 patients who participated in the study. The anti-nuclear antibody (ANA) test and anti-SS-A positivity rate were higher in the AT group (p value < 0.001 and 0.002 respectively). We found that the likelihood of developing AT increased as ANA titres increased. ANA positivity titres were found to be significant at 2+, 3+, and 4+ values (odd ratios 2.41, 3.40, and 4.21, respectively). Additionally, histological examination of salivary gland biopsies revealed a significantly higher prevalence of diffuse lymphocytic infiltration in the AT group. Conclusions: AT was present in 31% of patients with SD. The presence of ANA positivity, anti-SS-A positivity, and diffuse lymphocytic infiltration appears to exert an influence on the association between these two diseases
The effect of interface enhancement on the mechanical properties of fibre-reinforced PA6 matrix composites in material extrusion-based additive manufacturing
No full textUsing different fibres and ratios can considerably enhance the mechanical properties of thermoplastic composites, and the fibre-matrix interface plays a crucial role in realizing the effects of reinforcements. This research aims to enhance the fibre-matrix interface using sustainable resources to increase the mechanical properties of composites produced using additive manufacturing. To do this, cellulose nanofibrils (CNF) were used for surface modification of carbon, glass, and hybrid (carbon + glass) fibres used in reinforcements in the PA6 matrix. Samples were produced by 3D printing done through material extrusion (MEX). and the effects of fibre types and ratios, print layer thickness, and interface enhancement between fibre-matrix on mechanical properties were investigated experimentally. Results reveal a 5 to 11% increase in the tensile strength of the carbon fibre-reinforced samples, whereas a 72 to 88% increase was observed for the glass fibre-reinforced samples. Furthermore, the tensile modulus value has been increased 4 times in carbon fibre reinforcement samples that used modified fibre compared to PA6 pure. Finally, different types and ratios of fibres had an impact on the glass transition temperature, but there was little to no change in the melting and crystallization temperatures. Our work highlights the potential of the proposed CNF modification made to the fibres for MEX production to produce parts with higher mechanical properties.Idot;KCU BAP [2021-TDR-FEBE-0003]; TUBITAK [2214A]The author, A Dogru received TUBITAK 2214A support to carry out his studies at the University of Alberta. In addition, funding was provided for materials, tests, and analyses within the scope of A Dogru's doctoral thesis with the & Idot;KCU BAP project numbered 2021-TDR-FEBE-0003. The authors gratefully acknowledge the valuable contribution made by the Eurotec Company in the production of compound raw materials
L’exposition du voile islamique sous réserve des décisions de la Cour Européenne des Droits de L’Homme
No full textCelem artykułu jest analiza wybranego orzecznictwa Europejskiego Trybunału Praw Człowieka w przedmiocie manifestacji własnej religii lub przekonań poprzez noszenie chusty islamskiej. Autorka – w porządku chronologicznym – charakteryzuje następujące wyroki/decyzje Europejskiego Trybunału Praw Człowieka: decyzję Dahlab przeciwko Szwajcarii, wyrok Leyla Sahin przeciwko Turcji i wyrok Dogru przeciwko Francji. Prezentowany artykuł zawiera charakterystykę okoliczności sprawy, właściwe prawo krajowe, postępowanie i rozstrzygnięcie Trybunału, a w konsekwencji – interpretację orzeczenia.The aim of the article is the analysis of the selected jurisprudence of the European Court of Human Rights concerning manifestation of one’s religion or beliefs because of wearing Islamic headscarf. The Author – according to the chronological order – takes into consideration the following judgments/decisions of the European Court of Human Rights: Decision Dahlab v. Switzerland, Judgment Leyla Sahin v. Turkey and Judgment Dogru v. France. The presented article contains the characteristic of the circumstances of the case, the relevant domestic law, the proceedings and Court decision and finally – interpretation of the judgment
A fixed point approach to singular impulsive boundary value problems
No full textWe obtain sufficient conditions for existence and uniqueness of solutions for a class of second order nonlinear singular impulsive boundary value problems with fixed moments of impulses
GEOGRAPHICAL INFORMATION SYSTEMS AIDED TRAFFIC ACCIDENT ANALYSIS CASE STUDY: CITY OF ERZURUM NORTH RING ROAD
No full textThe population growth in developing World, technological development and urbanization is directly connected with the systems of transportation. Although transportation sector offers pretty much alternatives nowadays, people heavily prefer to highway transportation mode in the east of Turkey. The studies which have been done for providing road safety decrease traffic accidents. Geographical Information System (GIS) technology has been a popular tool for accident data and analysis of black spots in highways. Many traffic agencies have been using GIS for accident analysis. Accident analysis studies aim at the identification of high rate accident locations and safety deficient areas on the highways. A case study, using GIS aided traffic accident analysis for The North Ring Road of Erzurum/Turkey were developed by using the historical data, between 2005 and 2012. In conclusion, this study focused on the practicability of the GIS with the maps for traffic safety analysis
Reply to the letter to the author concerning: 'Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?'
No full textWOS: 000425281500025PubMed ID: 29423746We would like to thank the author for making valuable comments about our article entitled “Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?” [1]. However, we think that the reviewer has made several mistakes while evaluating the content of our article and the details of the literature. Firstly, as we have already pointed out in our trial, our study aims to evaluate the presence of adenoid hypertrophy (AH) in children with allergic rhinitis (AR) and the connection between AH disease severity and clinical laboratory findings. The aim of the study is not about exploring the effects of adenoidectomy on the patients with AR and A
Challenges of intercultural communication in the context of healthcare facilities
No full textDie kulturelle Vielfalt in Österreich bringt einige Schwierigkeiten mit sich, die vor allem für Migrant*innen, die der deutschen Sprache nicht mächtig sind, zu Herausforderungen beim Zugang zu und der Nutzung des Gesundheitssystem führen können. Ziel dieser vorliegenden Arbeit ist es, die vorhandenen Schwierigkeiten und Herausforderungen zu identifizieren und Lösungsansätze aufzuzeigen.
Die Autorin dieser Arbeit hat mithilfe eines semistrukturierten Interviewleitfadens Daten von Migrant*innen erhoben, um die bestehenden Problemfelder in österreichischen Gesundheitseinrichtungen zu analysieren. Die Ergebnisse der Interviews kristallisieren die spezifischen Barrieren und Herausforderungen heraus, die Migrant*innen im österreichischen Gesundheitssystem erleben. Zusätzlich wurden in verschiedenen Wiener Gesundheitseinrichtungen Beobachtungen durchgeführt, wobei ein besonderer Fokus auf die kulturelle Vielfalt und die sprachliche Barrierefreiheit gelegt wurde.
Basierend auf den erhobenen Daten zeigt die Arbeit, dass die Hauptprobleme im Gesundheitssystem vor allem in der mangelnden sprachlichen Verständigung, dem begrenzten Zugang zu Übersetzungsdienstleistungen und kulturellen Fehleinschätzungen liegen. Die Arbeit schließt mit möglichen Lösungsansätzen, die zur Verbesserung der interkulturellen Kompetenz des Gesundheitspersonals helfen sollen. Darüber hinaus werden Lösungsvorschläge gemacht, die zu einer besseren Kommunikationsstrategie helfen sollen, damit der Zugang zum Gesundheitssystem für Migrant*innen erleichtert wird und eine gerechtere Gesundheitsversorgung gewährleistet werden kann.Cultural diversity in Austria brings with it a number of difficulties that can lead to challenges in accessing and using the healthcare system, especially for migrants who do not speak German. The aim of this thesis is to identify the existing difficulties and challenges and to find possible solutions.
The author of this thesis used a semi-structured interview guide to collect data from migrants in order to analyse the existing problem areas in Austrian healthcare facilities. The results of the interviews give a glimpse into the specific barriers and challenges experienced by migrants in the Austrian healthcare system. In addition, observations were carried out for the study, in different Viennese healthcare facilities, with a particular focus on cultural diversity and linguistic accessibility.
Based on the data collected, the thesis shows that the main problems in the healthcare system lie primarily in the lack of linguistic understanding, limited access to translation services and cultural misconceptions. The paper concludes with possible solutions to help improve the intercultural competence of healthcare workers. In addition, solutions are proposed to help develop a better communication strategy to facilitate access to the healthcare system for migrants and ensure more equitable healthcare.Abweichender Titel laut Übersetzung der Verfasserin/des VerfassersMasterarbeit Wien, FH Campus Wien 202
Association of synaptosomal-associated protein 25 (SNAP-25) gene polymorphism with temperament and character traits in women with fibromyalgia syndrome
No full textAbstract Background: Synaptosomal-associated protein 25 (SNAP-25) may be contribute to the pathogenesis of fibromyalgia Syndrome (FMS) by affecting the release of neurotransmitters. Objectives: We aimed to investigate the relationship between the SNAP-25 gen (DdeI = rs1051312 and MnlI = rs3746544) polymorphism and the temperament and character traits. Methods: A total of 85 female patients diagnosed with FMS and 70 age-matched healthy female subjects were enrolled into the study. The Temperament and Character Inventory (TCI) were performed on all the patients. SNAP-25 gene polymorphism was determined in the patients group and controls group. Results: No significant difference between groups was found regarding the distribution of SNAP-25 MnlI polymorphism (p > 0.05), but it was seen that the frequency of TC genotype for DdeI gene was higher in the patients group (p 0.05). However, increased hazard avoidance was detected in patients with TC genotype for DdeI gene compared to patients without such genotype. Discussion: SNAP-25 might be an etiological factor in FMS pathogenesis and might affect personality traits of FMS patients by mediating neurotransmitter release.</div
Current Smoking Status Increases the Risk of Axial Psoriatic Arthritis: An Explanation to Smoking Paradox
No full textCurrent Smoking Is Increased in Axial Psoriatic Arthritis and Radiographic Sacroiliitis
No full textObjective. The effect of smoking in psoriatic arthritis (PsA) is under debate. Our aim was to test whether smoking is increased in axial PsA (axPsA). Methods. Included in the analysis were 1535 patients from PsArt-ID (PsA-International Database). The effect of smoking on axPsA (compared to other PsA phenotypes) and radiographic sacroiliitis were investigated. Results. Current smoking was more common in axPsA (28.6% vs 18.9%, p < 0.001). It also was found as an independent predictor of axPsA (OR 1.4) and radiographic sacroiliitis (OR 6.6). Conclusion. Current smoking is significantly associated with both axPsA and radiographic sacroiliitis in patients with PsA
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