110 research outputs found

    Manfred Max Neef y la revolución ambientalista para América Latina, 1932-2019 (in memoriam)

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    With the article, it is offered a tribute to the work of Manfred Max Neef, Chilean intellectual, politician, ecologist and economist, Alternative Nobel Prize winner in Economics, a pioneer in ecological criticism of both productivism and extractivism in Latin America. The methodology used in this work is based on the review of the main books published by the author, such as Barefoot Economy (1982), Development on a Human Scale (1986), The Lost Dimension (2007), and The Unmasked Economy (2014). It is held as an assumption that Max Neef’s work fits into a Latin American theoretical body, which breaks intellectually with macroeconomic models, be they developmentalist or neoliberal in nature. The originality of his contribution is in the defense of the ecological foundations for human development at a local scale.Con el artículo, se ofrece un homenaje a la obra de Manfred Max Neef, intelectual, político, eco- logista y economista chileno, Premio Nobel Alternativo en Economía, pionero en la crítica ecológica, tanto en el productivismo como en el extractivismo en América Latina. La metodología empleada en este trabajo se funda en la revisión de los principales libros publicados por el autor, tales como Economía descalza (1982), Desarrollo a escala humana (1986), La dimensión perdida (2007) y La economía desenmascarada (2014). Se sostiene como supuesto que la obra de Max Neef se encuadra en un cuerpo teórico latinoamericano, que rompe intelectualmente con los modelos macroeconómi- cos, sean de corte desarrollista o de tipo neoliberal. La originalidad de su aporte se encuentra en la defensa de los fundamentos ecológicos para el desarrollo humano a una escala local

    Author response: The synaptic ribbon is critical for sound encoding at high rates and with temporal precision

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    We studied the role of the synaptic ribbon for sound encoding at the synapses between inner hair cells (IHCs) and spiral ganglion neurons (SGNs) in mice lacking RIBEYE (RBEKO/KO). Electron and immunofluorescence microscopy revealed a lack of synaptic ribbons and an assembly of several small active zones (AZs) at each synaptic contact. Spontaneous and sound-evoked firing rates of SGNs and their compound action potential were reduced, indicating impaired transmission at ribbonless IHC-SGN synapses. The temporal precision of sound encoding was impaired and the recovery of SGN-firing from adaptation indicated slowed synaptic vesicle (SV) replenishment. Activation of Ca2+-channels was shifted to more depolarized potentials and exocytosis was reduced for weak depolarizations. Presynaptic Ca2+-signals showed a broader spread, compatible with the altered Ca2+-channel clustering observed by super-resolution immunofluorescence microscopy. We postulate that RIBEYE disruption is partially compensated by multi-AZ organization. The remaining synaptic deficit indicates ribbon function in SV-replenishment and Ca2+-channel regulation

    Author response: Gender bias in scholarly peer review

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    Peer review is the cornerstone of scholarly publishing and it is essential that peer reviewers are appointed on the basis of their expertise alone. However, it is difficult to check for any bias in the peer-review process because the identity of peer reviewers generally remains confidential. Here, using public information about the identities of 9000 editors and 43000 reviewers from the Frontiers series of journals, we show that women are underrepresented in the peer-review process, that editors of both genders operate with substantial same-gender preference (homophily), and that the mechanisms of this homophily are gender-dependent. We also show that homophily will persist even if numerical parity between genders is reached, highlighting the need for increased efforts to combat subtler forms of gender bias in scholarly publishing

    Modelling Capillary Effects in Heterogeneous Porous Media

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    Electrical Engineering, Mathematics and Computer Scienc

    Bringing Law to the Community: Facilitating Access to Justice in Metropolitan Detroit

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    Wayne County is Michigan’s most populous county with 1.775 million residents and its county seat in Detroit. Unlike many other counties throughout the state, Wayne county does not provide a government-supported law library to serve its residents. The Arthur Neef Law Library which serves the Wayne State University Law School has a long-standing tradition of opening its doors to provide legal research services and resources to members of the community. A fundamental mission of the Law Library, as well as the entire University, is “…meaningful engagement in its urban community”. Legal professionals, students and faculty from other educational institutions, and community residents who need legal information are referred to, and depend on, the Arthur Neef Law Library collections and librarian expertise. Community patrons typically account for approximately seventy percent of reference desk patrons. Librarians provide traditional reference and research services, as well as instruction in basic legal research and the use of database, government information, open access and free web resources, legal self-help materials and print publications to community patrons. The diverse experience levels of community patrons, including literacy and technical skills, familiarity with legal materials, and communication abilities, provide unique challenges. One of the most compelling is the need for librarians to balance patron expectations with the best use of the library\u27s resources. Collaboration with, and connections to, other librarians and libraries (law and non-law), as well as knowledge of their collections plays a significant role in facilitating access to justice for community patrons

    Treatment of boundaries in unsteady inviscid flow computations

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    Aerospace Engineerin
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