72 research outputs found
Whoever tramples the breadcrumbs will go blind: Cultural norms regarding feeding children and eating in Bulgarian society. A conversation between Petya Bankova and Vihra Baeva
Get PDFPetya Bankova is Associated Professor in the Institute of Ethnology and Folklore Studies with Ethnographic Museum at the Bulgarian Academy of Sciences (Sofia, Bulgaria). Her scientific interests concern in the field of anthropology of childhood, children plays, and the everyday life culture during the communist period in Bulgaria. She is the author of three monographs: Images and Meetings in the Tradition, They Recognized him by his Name: Ethno-confessional Aspects of the Given Name in Bulgaria, and The Magic of the Given Name, as well as co-author of Almanac. Traditions and Holidays of the Bulgarians. She has co-edited several volumes, the last of which is Sociocultural Dimensions of Childhood (Sofia 2020)
Erken Sönen Güneş Işığı: Şair Petya Dubarova‘nın Hüzünlü Hikayesi
No full textÖz: Bulgar edebiyatının en yetenekli, en genç ve en ünlü temsilcilerinden biri olan Petya Dubarova Türkiye’de pek tanınmayan bir şairdır. Bu nedenle bu araştırmanın öncelikli amacı Bulgar yazarı Türk okuyucularına ve bilim dünyasına tanıtmaktır. Haksızlıklar ve adaletsizlik karşısında dik durduğu için Petya dünyayı çok erken terk etmiş. Muhteşem yeteneğini sonuna kadar ortaya çıkarmadan ve belki de en güzel şiirlerini kaleme almadan daha 17 yaşında intihar ederek yaşama veda etmiştir. Bu araştırmada Dubarova’nın renkli ve hüzünlü hayat hikâyesi büyüteç altına alınmış, ayrıca hem “Öğrenci Petya”nın hem de “Şair Petya”nın portresi resmedilmeye çalışılmıştır. Araştırmanın özeğinde Petya’nın öz yaşamı, romantik aşkları, öğrencilik yılları, yaşadığı kişisel sorunlar ve yazarlık yeteneği yer almaktadır. Petya Dubarova Bulgaristan’ın unutulamayan, henüz çocuk yaşta olağanüstü yeteneğiyle dikkat çeken şairlerinden biridir. Onun şiirsel kalıtı genellikle çocuksu arılığı, ergenlik yürekliliğini, felsefi sorgulamaları ve müthiş yaratıcılığı yansıtmaktadır. Dubarova geride yüzlerce yanıtsız soru bırakarak, çok genç yaşta yaşamına son vererek bizlerden ayrılmıştır. Kısa yaşamında bizi şaşırtmayı başarmış, ne var ki muazzam yeteneğinin yalnızca küçük bir ipucu vermiştir bizlere. Yaşamında da ölümünden sonra da bu genç yetenek tam olarak kavranamamış ve çevresindeki gizemli bulut da bir türlü çözülememiştir. Türk okuyucuları çocuk yaştaki bu yazarı pek bilmedikleri için hüzünlü yaşam serüvenini ve ozan olarak başarılarını bir makalede irdelemenin yararlı olacağı düşünülmüştür. Bu araştırmanın, Bulgar edebiyatı alanında ülkemizde önemli bir yayın boşluğunu doldurması umut edilmektedir.As one of the most talented, youngest, and renowned writers of Bulgaria, Petya Dubarova is a poet relatively unknown in Türkiye. Therefore, the primary purpose of this study is to introduce the Bulgarian author to the Turkish readers and the academic world. Petya departed this world way too prematurely because she confronted and resisted against the injustice and unfairness. Without revealing her amazing talent to the fullest and perhaps without writing her most beautiful poems, she bid farewell to the world by committing suicide at the age of 17. The present study focused on the colorful and sad life story of Dubarova, and the portrait of both the "Student Petya" and "Poet Petya" was depicted. The crux of this study includes Petya's personal life, her romantic affairs, her years as a student, her personal problems and her talent as a writer. Petya Dubarova is one of Bulgaria's most memorable and mystifying talented juvenile poets. Her poetic legacy often reflects childlike innocence, adolescent chivalry, philosophical inquiry and unearthly creativity. Dubarova departed this world, leaving behind hundreds of unanswered questions and ending her life at a very young age. She really managed to mystify us in her very short span of life and more importantly, demonstrated us only a small hint of her enormous talent. This young talent failed to be fully appreciated during her life or after her death, and the mystery around her could not be identified. Since Turkish readers are mostly unfamiliar with this tender- age writer, we are of the opinion that it will be worth of while to investigate her sad life adventure and her achievements as a poet in an article. It is believed that this study will fill an important scientific publication gap in Turkey in the field of Bulgarian literature
Conceptual Model of Decision Making Information Used by Managers in Bulgarian Non-hospital Medical Organizations
No full textPetya parent - "socialist" fatherhood in Mladý svět magazine at the end of the 70th and beginning of the 80s of the 20th century
Get PDFBc. Kateřina Vlčková ABSTRACT: Petya parent - "socialist" fatherhood in Mladý svět magazine at the end of the 70th and beginning of the 80s of the 20th century The topic of my thesis is fatherhood in socialist Czechoslovakia in the late 70s and 80s of the 20th century. My primary source research is a section Péťa Parent, published from 1979 to 1982 in the Mladý svět magazine. The uniqueness of this column, I see in the fact that the author (Petr Hora-Hořejš) as the father advise to "public" readers regarding about education and child care. The theoretical part will focus on the concepts that are relevant to my research, such as the gender culture, fatherhood, masculinity, private and public sphere, motherhood, femininity, etc. Among the basic questions I'll ask include the following: How "socialist" father defends and publishes his paternal role, how he views care and education (his) child or what image of man-father Mladý svět magazine helps to create. With my work I try to contribute to a greater awareness of the history of fatherhood changes and involvement father in a family area, which was at that time primarily attributed to the women-mothers
Erratum to: The political economy of adult learning systems
No full textIn the Editorial of this issue, Miroslav Stefanik was accidentally stated as the single author of the article “Multi-layered Perspective on the Barriers to Learning Participation of Disadvantaged Adults”. The article is a joint authorship by Sofie Cabus, Petya Ilieva-Trichkova and Miroslav Stefani
PCR screening of feed products for the detection of genetically modified soybean
No full textAfter the development and approval for commercial use of more than 570 genetically modified crop events worldwide, the ability of qualitative identification and quantification of transgenic materials in feed has become an essential necessity and a serious challenge in terms of feed safety. In the present study, a PCR screening of feed products for the detection of GM soybeans was conducted. The CTAB extraction method yielded high-quality DNA extracts, with concentrations ranging from 145.25 ng/µl to 442.68 ng/µl and excellent purity (A260/A280 = 1.80 – 1.88). The LOD of the PCR method for soybean DNA detection was less than 1 soybean genome copy, demonstrating the high sensitivity of the method. The concentration of 0.01% target DNA was determined as LOD of both PCR methods for the detection of the CaMV 35S promoter and the EPSPS gene. Therefore, they could be applied for the screening of various feed products for the presence of genetically modified DNA. Furthermore, the CaMV 35S promoter and the EPSPS gene were observed in 77.78% of the analyzed feed products. This demonstrated the widespread distribution of GM crops in feed and set the necessity of strict control for the presence of GMO in the feed industry
Molecular-genetic characteristics of patients with cardiomyopathy in Bulgaria
No full textРЕЗЮМЕ
Kaрдиомиопатиите представляват хетерогенна група заболявания от клинична и от генетична гледна точка, които се характеризират с разнообразни модели на унаследяване, непълна пенетрантност и вариабилна експресия. Генетичните изследвания при индексните пациенти имат ключово значение за потвърждаване на генетичната диагноза, като идентифицираните генетични варианти могат да послужат за провеждането на каскаден скрининг с цел определянето на близки родственици в риск от развитие на заболяването или изключването на този риск при други членове на семейството в съответствие с актуалните клинични препоръки. При двойките във фертилна възраст е възможно провеждането на репродуктивна консултация. Настоящият дисертационен труд предоставя първите обобщени данни по отношение на молекулярно-генетичните характеристики при пациенти с кардиомиопатия в България, както и данни относно генотип-фенотипни корелации. Получените резултати от WES и проведения молекулярно-генетичен анализ при 80 български пациенти с кардиомиопатия показват наличието на генетични находки при 85% от тях, както и висока честота на новооткрити варианти, които не са докладвани в съвременните бази данни, която достига ~30%. Вероятно патогенни/патогенни варианти се установяват при ~46% oт пациентите с ХКМП без данни за фамилна анамнеза, при ~53% от пациентите с ХКМП с данни за фамилна анамнеза, при 50% от пациентите със спорадична ДКМП, като честотата достига 80% при пациентите с ДКМП с положителна фамилна анамнеза, а също и при пациентка с неуточнена кардиомиопатия. При пациентите с РКМП в изследваната група не се установяват генетични находки във връзка с изявената клинична симптоматика. Сегрегационни анализи чрез директно секвениране по Sanger бяха проведени в 14 от засегнатите семейства. В проучваната група се установява статистически значима разлика по отношение на по-ранна възраст на oткриване на заболяването при пациентите, носители на LP/P варианти и пациентите, носители на LP/P варианти в саркомерни гени спрямо пациентите без идентифицирани генетични находки. Известни генотип-фенотипни корелации могат да имат роля в персонализирания подход по отношение на оценка на риска и определяне на поведението при пациентите с кардиомиопатия. Получените peзултати от проучванията в рамките на дисертационния труд са в подкрепа на приложението на генетични изследвания и медико-генетично консултиране при пациентите и засегнатите семейства с кардиомиопатия в България.
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SUMMARY
Cardiomyopathies are a heterogeneous group of diseases from a clinical and genetic point of view, characterized by diverse inheritance patterns, incomplete penetrance and variable expression. Genetic studies in index patients are of key importance for confirming the genetic diagnosis, as the identified genetic variants can be used for conducting cascade screening in
order to determine close relatives at risk of developing the disease or to exclude this risk in other family members in line with current clinical guidelines. Reproductive counseling may be
provided to couples of fertile age. This dissertation provides for the first time pooled data on molecular-genetic characteristics in patients with cardiomyopathy in Bulgaria, as well as data on genotypephenotype correlations. The results of WES and molecular genetic analysis in 80 Bulgarian patients with cardiomyopathy show the presence of genetic findings in 85% of them, as well as a high frequency of newly discovered variants that have not been reported in contemporary databases, reaching ~30%. Likely pathogenic/pathogenic variants are found in ~46% of patients with HCM without family history, in ~53% of patients with HCM with family history, in 50% of patients with sporadic DCM, the frequency reaching 80% in patients with DCM with a positive family history, and also in a patient with unspecified cardiomyopathy. In patients with RCM in the studied group, no genetic findings were identified related to the clinical symptoms. Segregation analyses by direct Sanger sequencing were performed in 14 of the affected families. In the studied group, a statistically significant difference was found in terms of an earlier age of disease detection in patients carrying LP/P variants and patients carrying LP/P variants in sarcomeric genes compared to patients without identified genetic findings. Known genotype-phenotype correlations may have a role in the personalized approach to risk assessment and management of patients with cardiomyopathy. The results obtained from the studies within the dissertation work support the application of genetic testing and medical-genetic counseling in patients and affected families with cardiomyopathy in Bulgaria
Comparative study of DNA extraction methods for identification of medicinal mushrooms
No full textThe isolation of high quantity and intact DNA is of a great significance for molecular identification of higher fungi. The aim of this study was to compare two DNA extraction methods for isolation of DNA from medicinal mushrooms of Agaricomycetes class. A modified CTAB method and a modified SDS method were compared by the yield and purity of the extracted DNA, its fragmentation state and suitability for amplification. The results demonstrated high efficiency of both methods in regard to DNA yield (14.18 -144.28 ng DNA/mg biomass with CTAB method and 15.03 -108.34 ng DNA/mg biomass with SDS method). The CTAB method provided DNA extracts with higher purity (A260/A280 ranged from 1.83 to 1.99) in comparison with the SDS method (A260/A280 = 1.53 -1.86). The modified CTAB method produced amplifiable DNA from all mushroom isolates, while the SDS method demonstrated suitability for amplification only in 50% of the samples. Therefore, the modified CTAB method could be the method of choice for DNA extraction from medicinal mushrooms. The analyzed isolates were subjected to molecular identification by ITS1-5.8S-ITS2 rRNA gene sequence analysis and were identified as Ganoderma resinaceum, Trametes versicolor, Fomitopsis pinicola and Inonotus hispidus
Терапевтичен подход при приложението на инхалаторен азотен окис в неонаталния период
No full textЦЕЛ И ЗАДАЧИ
ЦЕЛ: Изследване ефекта от приложението на инхалаторен азотен окис при новородени с различна гестационна възраст с оглед изработване на адекватни модели за провеждане на терапия в неонаталния период.
ЗАДАЧИ:
I група ≥ 34 г.с.:
1. Да се проучат факторите, свързани с бременността, акушерското поведение и ранния неонатален период, които са свързани с развитието на Персистираща белодробна хипертония на новороденото.
2. Да се анализира терапевтичния ефект на iNO чрез използване на обективния критерии за тежест на заболяването: OI.
3. Да се анализират настъпилите странични ефекти по време на провежданата терапия.
4. Да се направи сравнение на лечението с iNO и конвенционалната терапия на Персистираща белодробна хипертония по отношение на:
o Летален изход;
o Хронични усложнения: Неврологични увреждания (промени в ТФЕ) и БПД;
o Продължителност на болничен престой.
5. Да се изработи протокол за провеждане на терапия на PPHN с iNO в неонаталния период.
II група ≤ 30 г.с. :
1. Да се проучат факторите, свързани с бременността, реанимацията в родилна зала и ранния неонатален период, които са свързани с развитието на Бронхопулмонална дисплазия.
2. Да се анализира терапевтичния ефект на iNO при недоносени деца с Белодробна хипертония и повишен риск за развитие на Бронхопулмонална дисплазия.
3. Да се изработи протокол за провеждане на терапия с iNO при недоносени деца под 30 г.с
Specifics in the Contemporary Development of Hotel Business in Bulgaria
No full textThe author analyses the numerical alteration of the number of hotels in Bulgaria in the recent years, the current specifics and problems in the hotel business. The correlations between this alteration and the number of fulfilled night-stays, the increase rate of the lodging base and the correspondence to the alterations in the employment in it. The dynamics in the development of the hotel business is examined in a territorial section and regarding the criteria “hotel category”. The author puts an emphasis on the factors that hamper the hotel business, the current requirements and trends. On this ground general conclusions are made and some recommendations on the utilization of the existing potential of the hotel business in Bulgaria are made.
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