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Vaikų, sergančių limfangioma, gydymo preparatu OK-432 (picibaniliu) patirtis
No full textGintarė Breivienė, Marytė Malevskienė, Andrius Čekuolis, Kęstutis Trainavičius
Vilniaus universiteto Vaikų ligoninė, Vaikų chirurgijos centras, Vilniaus universiteto
Vaikų ligoninės Chirurgijos centras, Santariškių g. 7, LT-08406 Vilnius
El paštas: [email protected]
Įvadas / tikslas
Pagrindinis limfangiomos gydymo būdas – jos pašalinimas. Tačiau radikaliai limfangiomą pašalinti ne visada įmanoma. Todėl ieškoma alternatyvių gydymo būdų. Pastaruoju metu labai paplito limfangiomų gydymas preparatu OK-432 (picibaniliu). Tyrimo tikslas – įvertinti vaikų limfangiomų gydymo rezultatus preparatu OK-432 (picibaniliu)..
Ligoniai ir metodai
Per 12 metų (1995–2006) preparatu OK-432 buvo gydyti 26 ligoniai (nuo 6 mėn. iki 15 metų amžiaus), sergantys įvairios lokalizacijos limfangiomomis. Cistine (makrocistine) limfangiomos forma sirgo 14 ligonių, kavernine (mikrocistine) – 12 ligonių.
Rezultatai
Trylika iš 14 ligonių, kurie sirgo cistine limfangiomos forma, pasveiko. Viena ligonė, nepadėjus skleroterapijai, buvo operuota. Iš 12-os sirgusiųjų kavernine forma visai pasveiko trys, labai pagerėjo šešiems, truputį pagerėjo trims.
Išvada
Mūsų patirtis leidžia daryti išvadą, kad OK-432 yra veiksmingas vaistas gydant cistines limfangiomas, taip pat jis padeda ir daliai ligonių, sergančių kavernine ligos forma.
Pagrindiniai žodžiai: cistinė limfangioma, kaverninė limfangioma
OK-432 (Picibanil) therapy in children with lymphangioma
Gintarė Breivienė, Marytė Malevskienė, Andrius Čekuolis, Kęstutis Trainavičius
Vilnius University Children’s Hospital, Center of Pediatric Surgery,
Santariškių 7, LT-08406 Vilnius, Lithuania
E-mail: [email protected]
Background / objective
The aim of this study was to evaluate the results of treatment with OK-432 of lymphangioma patients.
Patients and methods
During 12 years (1995–2006) we treated 26 children for lymphangiomas with OK-432. Their age ranged from 6 months to 15 years. Fourteen patients had cystic lymphangioma and 12 had cavernous lymphangioma.
Results
Thirteen patients with cystic lymphangioma recovered. One patient was operated on because of unsuccessful therapy, 3 patients from the 12 with cavernous lymphangiomas had a total shrinkage, 6 patients had a marked shrinkage and 3 a slight shrinkage.
Conclusions
Intralesional injection of OK-432 is an effective and safe treatment for lymphangiomas, especially for cystic lesions.
Key words: cystic lymphangioma, cavernous lymphangiom
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Vaikų uždaros pilvo traumos: diagnostika ir gydymas
No full textBenjaminas Siaurusaitis, Kęstutis Trainavičius, Gintarė Breivienė, Andrius Čekuolis, Arūnas Strumila
Vilniaus universiteto Vaikų ligoninė ir Vaikų ligų klinika
Santariškių g. 7, LT-08406 Vilnius
El paštas: [email protected]
Įvadas / tikslas
Dauguma vaikų uždarų pilvo traumų pastaraisiais metais išgydoma konservatyviai. Darbo tikslas – apžvelgti šių traumų gydymo taktiką per 25 metus ir jo rezultatus.
Ligoniai ir metodai
Retrospektyviai analizuota 1979–2003 metais gydytų 1139 vaikų uždarų pilvo traumų priežastys, sužalojimų klinikiniai ir tyrimų duomenys, gydymo metodai ir rezultatai.
Rezultatai
Vaikų uždaros pilvo traumos dažniausiai įvyksta dėl buitinių traumų ir autoįvykių. Daugėja smurtinių traumų. Dažniausiai sužalojama blužnis (174 ligoniai, 15,3% visų traumų). Kepenų sužalojimai nustatyti 42 ligoniams (3,7%). Dėl tikslesnės diagnostikos per pastaruosius 5 metus šių pažeidimų gydymo taktika tapo konservatyvesnė: neoperuojant išgydyti 39 iš 47 blužnies traumą patyrusių vaikų (83,0%) ir 10 iš 12 kepenų traumą patyrusių vaikų (83,3%). Vaikų ertminių pilvo organų sužalojimai reti: 36 ligoniai (3,2%). Visi kasos, dvylikapirštės žarnos traumas patyrę ligoniai buvo operuoti. Jie pasveiko. 865 ligoniams (75,9%) diagnozuotas tik pilvo sumušimas. Mirė 3 ligoniai (0,3%).
Išvados
Nauji šiuolaikiniai tyrimo metodai – echoskopija, kompiuterinė tomografija – labai pakeitė vaikų uždarų pilvo traumų gydymo taktiką. Dėl tikslesnės diagnostikos daugumą blužnies, kepenų, kasos sužalojimų galima išgydyti konservatyviai. Operuojama besitęsiant ar atsinaujinus kraujavimui ir esant nestabiliai hemodinamikai.
Reikšminiai žodžiai: vaikų uždaros pilvo traumos, pilvo organų sužalojimai, diagnostika, chirurginio gydymo taktika
Blunt abdomen injury in children: diagnosis and treatment
Benjaminas Siaurusaitis, Kęstutis Trainavičius, Gintarė Breivienė, Andrius Čekuolis, Arūnas Strumila
Background / objective
The large majority of children with blunt abdomen trauma are treated non-operatively. The aim of our study was to analyze the tactics of treatment of blunt abdomen trauma and the results of 25 years.
Patients and methods
The retrospective study of 1139 patients treated in our clinic between 1979 and 2003 has been undertaken. Causes of trauma, clinical and diagnostic data, methods of treatment and results were analyzed.
Results
The most common causes of injuries were conditions of life and motor vehicle accidents, but violent traumas were also frequent. Spleen injury was the most frequent blunt trauma (174 patients, 15.3%). Hepatic trauma was diagnosed in 42 patients (3.7%). The diagnosis was made clinically and confirmed by sonography. The background for non-operative treatment was the precise diagnostics including CT-scan: in the last 5 years 83% of spleen (39 patients) and liver (10 patients) injuries were treated non-operatively. All 36 patients (3.2%) with intestinal injuries were operated on. Injuries of the retroperitoneal organs (duodenum, pancreas) were rare. The diagnosis was confirmed by CT. All patients were operated on and recovered. The large majority of patients (865 patients, 75.9%) underwent only abdomen contusion. There were 3 deaths (0.3%).
Conclusions
New diagnostic modalities, sonography and CT-scan, changed the management of patients with blunt abdominal trauma. Most patients with liver and spleen blunt injuries are treated non-operatively. Operative treatment is indicated if there are signs of continuing bleeding and patients are hemodinamically unstable.
Keywords: blunt abdomen injury in children, intraabdominal injuries, diagnosis, tactics of surgical treatmen
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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