138 research outputs found
Análisis, desarrollo y fabricación de medios de traslación neumáticos y mejora del control electrónico del dispositivo EndoWorm
No full textSenent Cardona, E. (2011). Análisis, desarrollo y fabricación de medios de traslación neumáticos y mejora del control electrónico del dispositivo EndoWorm. Universitat Politècnica de València. https://riunet.upv.es/handle/10251/15485Archivo delegad
Ab initio spectroscopic studies of non-rigid molecules: An application to acetic acid
No full textThe torsional levels of various isotopologues of acetic acid are determined from an ab initio potential energy surface using a flexible model depending on the OH-torsion and the methyl-torsion coordinates. Previous calculations for CH3-COOH and CH3-COOD are review and first theoretical energies of the one-deuterated species CH2D-COOH are provided. The zero point vibrational energy correction and an exact definition for the methyl-torsional coordinate have been considered. The levels are compared with previous calculations (Senent in Mol Phys 99:1311, 2001) and experimental data (Havey et al. in J Mol Spectrosc 229:151, 2005). Isotopic effects on the torsional barriers and energies are discussed. For CH2D-COOD, the deuteration splits by 25 cm-1 the zero vibrational energy level. © 2011 Springer Science+Business Media, LLC.The author acknowledges the Ministerio de Ciencia e Innovación of SPAIN for the grants AYA2008-00446 and AYA2009-05801-E/AYA and to CESGA for computing facilities.Peer Reviewe
Estudio de cavidades optomecánicas como biosensores duales ultra-sensibles
No full text[ES] Los avances en nanotecnología, junto con la creciente necesidad de biosensores ultrasensibles, han aumentado drásticamente el interés por la fabricación a nanoescala de resonadores fotónicos, nanomecánicos y, en última instancia, optomecánicos. La optomecánica de cavidades, que se basa en el poderoso paradigma de la interacción luz-sonido en la nanoescala, emerge como tecnología clave para la detección altamente sensible de entidades biomoleculares por medio de los espectros óptico y mecánico. En este trabajo se demuestra el potencial de detección de un cristal optomecánico de ultra alta frecuencia basado en un chip de silicio que opera en condiciones ambientales. Los cambios de frecuencia ópticos y mecánicos debidos a la funcionalización de la superficie con una monocapa de 3-aminopropiltrietoxisilano (APTES) evidencian claramente que los cristales optomecánicos allanan el camino hacia la biodetección lab-on-chip sin etiquetas para aplicaciones relacionadas con la salud.[EN] Advances in nanotechnology together with an increasing need of ultrasensitive biosensors have drastically raised the interest in the nanoscale fabrication of photonic, nanomechanical and ultimately optomechanical resonators. Cavity optomechanics, which fields the powerful paradigm of light-sound interaction in the nanoscale, emerges as key technology for the highly sensitive detection of biomolecular entities by means of both the optical and mechanical spectra. In this work the sensing potential of a silicon-chip-based ultrahigh frequency optomechanical crystal operating at ambient conditions is demonstrated. The optical and mechanical frequency shifts due to surface functionalization with a monolayer of 3-aminopropyltriethoxysilane (APTES) clearly evidence that optomechanical crystals pave the way towards lab-on-chip label-free bio-sensing for health related applications.[CA] Els avan¸cos en nanotecnologia, juntament amb la creixent necessitat de biosensors ultrasensibles, han
augmentat dr`asticament l’inter´es per la fabricaci´o a nanoescala de ressonadors fot`onics, nanomec`anics
i, en ´ultima inst`ancia, optomec`anics. L’optomec`anica de cavitats, que es basa en el poder´os paradigma
de la interacci´o llum-so en la nanoescala, emergeix com a tecnologia clau per a la detecci´o altament
sensible d’entitats biomoleculars per mitj`a dels espectres `optic i mec`anic. En aquest treball es demostra
el potencial de detecci´o d’un cristall optomec`anic d’ultra alta freq¨u`encia basat en un xip de silici que
opera en condicions ambientals. Els canvis de freq¨u`encia `optics i mec`anics deguts a la funcionalizaci´o
de la superf´ıcie amb una monocapa de 3-aminopropiltrietoxisilano (APTES) evidencien clarament
que els cristalls optomec`anics aplanen el cam´ı cap a la biodetecci´o lab-on-chip sense etiquetes per a
aplicacions relacionades amb la salut.Sanmartín Senent, A. (2021). Estudio de cavidades optomecánicas como biosensores duales ultra-sensibles. Universitat Politècnica de València. https://riunet.upv.es/handle/10251/172841TFG
METHYLAMINE TORSIONAL-WAGGING FIR SPECTRUM HNH BENDING ANGLE DENPENDENCE.
No full text1) Ab-initio determination of the torsional and wagging FIR spectrum of methylamine. Y. G. Smeyers, M. Villa and M. L. Senent. 2) M. Kreglewski and F. Winther, J. Mol Spectrosc., 156, 261 (1992). 3) M. Kreglewski, in Structure and Conformations of Non-Rigid Molecules, (Eds. J. Laane et al), NATO-ASI S., Kluwer Ac., Dordrecht, 1993, pp. 29-43.Author Institution: Instituto de Estructura de la Materia, C.S.I.C., Madrid, Spain; Department de Quimica, U. A. M-I.Av La Purisia y Mechoacan, CP 09340, Mexico D.F., MexicoThe methylamine potential energy function for the torsion and wagging vibration motions depend upon the HNH bendijng angle of the amine groun (1). By using the RHF/MP2 approximation and a 6-31G++(3df, 3pd) basis set the energy potential surface and the kinetic parameters are calculated by considring the HNH angle a constant and considering it as a variable. With the former results the expremental inveraion barrier (2) reported in the literature can be properly reproduced. With a suitable symmetry adupted potential funtion the torssonal-wagging energy levels are calculated and compared with available experimetantal dats (3). The former work introduces the NHN bending angle as a third variable in the torisional-wagging FIR spectrum and is an initial step in considering the methylamine as a three dimensional non-rigid molecule
Endoworm: A new semi-autonomous enteroscopy device
No full text[EN] Using enteroscopes with therapeutic capacity to explore the small intestine entails certain limitations, including long exploration times, patient discomfort, the need for sedation, a high percentage of incomplete explorations and a long learning curve. This article describes the advances and setbacks encountered in designing the new Endoworm enteroscopy system, a semi-autonomous device consisting of a control unit and three cavities that inflate and deflate in such a way that the bowel retracts over the endoscope. The system can be adapted to any commercial enteroscope. Endoworm was tested in different intestine models: a polymethyl methacrylate rigid tube, an in vitro polyester urethane model, an ex vivo pig model and an in vivo animal model. The general behavior of the prototype was evaluated by experienced medical personnel. The mean distance covered through the lumen was measured in each cycle. The system was found to have excellent performance in the rigid tube and in the in vitro model. The ex vivo tests showed that the behavior depended largely on the mechanical properties of the lumen, while the in vivo experiments suggest that the device will require further modifications to improve its performance.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors gratefully acknowledge the financial support from the Spanish Ministry of Economy and Competitiveness through Project PI12/01000 and also from UPV/IIS LA Fe through the Endoworm 3.0 Project. CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008–2011, Iniciativa Ingenio 2010, Consolider Program and CIBER Actions, and financed by the Instituto de Salud Carlos III with the assistance of the European Regional Development Fund.Sánchez-Diaz, C.; Senent-Cardona, E.; Pons, V.; Santonja Gimeno, AV.; Vidaurre Garayo, AJ. (2018). Endoworm: A new semi-autonomous enteroscopy device. Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine. 232(11):1137-1143. https://doi.org/10.1177/0954411918806330S113711432321
Proyecto de transformación de un antiguo molino de harina en museo mediante traslado de las instalaciones a un antiguo matadero en Pedralba (Valencia)
No full textConsulta en la Biblioteca ETSI Industriales (5690)[ES] El presente proyecto tiene como objeto la transformación de un antiguo molino de
harina en museo, mediante traslado de las instalaciones al antiguo matadero de
Pedralba, situado en la provincia de Valencia.
¿ En primer lugar se realizará un estudio general sobre el arte de la molinería, su
historia, el oficio y el proceso de la molienda. Posteriormente se realiza un
estudio descriptivo del sistema de funcionamiento y de las instalaciones del
antiguo molino de Pedralba.
¿ En segundo lugar, se seleccionaran las diferentes partes de la maquinaria que se
consideran adecuadas y de utilidad para su traslado al antiguo matadero del
pueblo, con el fin de crear un museo en este lugar.
¿ Por último, se propondrá un diseño de este futuro museo, describiendo las
posibles salas de las que pudiera constar, estudio de recorridos, lay-out,
instalaciones eléctrica y de protección contra incendios, organización del museo
y estudio económico del mismo.Pérez Garnes, A. (2006). Proyecto de transformación de un antiguo molino de harina en museo mediante traslado de las instalaciones a un antiguo matadero en Pedralba (Valencia). https://riunet.upv.es/handle/10251/37274.Archivo delegad
The Formation of C3O3H6Structural Isomers in the Gas Phase through Barrierless Pathways: Formation and Spectroscopic Characterization of Methoxy Acetic Acid
No full text17 pags., 6 figs., 10 tabs. -- Unified Astronomy Thesaurus concepts: Molecular physics (2058); Molecule formation (2076); Molecular spectroscopy (2095)Gas phase formation processes feasible at low temperatures are determined theoretically for 38 isomers obeying the C3O3H6 empirical formula, one of them, the simplest ketose dihydroxyacetone, has been observed in gas phase sources. A preliminary search for isomeric forms first targets ethoxy formic acid (C2H5-O-COOH) as the most stable isomer followed by lactic acid. Profiles corresponding to the minimum energy pathways reveal that the favored conformers of 14 of these isomers can be formed in the gas phase through 29 barrierless processes involving the OH∗, CH3O∗, HCO∗, CH3∗, CH2OH, HCOO∗, and OHCO∗ radicals, all of them observed in the interstellar medium. Kinetic rates are provided at 200, 298, and 500 K, confirming the suitability of 16 processes at low temperatures. Faster processes involve the OH hydroxyl radical whereas, to a lesser degree, the processes involving the HOCO radical and the methoxy methyl radical CH3O∗, are quite significant. Spectroscopic parameters (rovibrational and torsional) are obtained for methoxy acetic acid (CH3-O-CH2COOH) for which two low-lying isoenergetic conformers can be produced from the CH3OCH2∗ radical predicted to be a precursor of abundant observed molecules. Profiles and spectroscopic properties make methoxy acetic acid a good candidate to be detected in the gas phase of extraterrestrial sources.This project has received funding from the European Unionʼs Horizon 2020 research and innovation program under
the Marie Sklodowska-Curie grant agreement No. 872081. This research was supported by the Ministerio de Ciencia,
Innovación y Universidades of Spain through the grants EIN2019-103072 and FIS2016-76418-P. This work has
received funding from the CSIC i-coop+2018 program under the reference number COOPB20364. V.G. acknowledges
CONACyT (México) for the postdoctoral grants 2018-000022-01EXT-00386. The author acknowledges the CTI
(CSIC) and CESGA and to the “Red Española de Computación” for the grants AECT-2020-2-0008 and RES-AECT2020-3-0011 for computing facilities
The large amplitude motions of methylamine from the perspective of the highly correlated ab initio methods
No full text6 pags., 2 figs. 3 tabs.CCSD(T)-F12 theory in connection with extended basis sets is employed to determine the electronic ground state spectroscopic parameters of methylamine at low temperatures. The geometry, the rotational constants, all the fundamental frequencies, the dipole moment and its components, and the centrifugal distortion constants, are provided. The ground vibrational state rotational constants were found to be A = 103067.15 MHz, B = 22588.29 MHz, and C = 21710.50 MHz and the dipole moment to be 1.4071D. Fermi displacements of the vibrational bands are predicted. The low vibrational energy levels corresponding to the large amplitude motions are determine variationally using a flexible three-dimensional model depending on three variables: the HNH bending, the NH wagging and the CH torsional coordinates. The computed levels are compared with previous experimental and calculated energies. Methylamine parameters are very sensitive to the level of ab initio calculations.This research was supported by the FIS2013-40626-P and FIS2016-76418-P projects of the MINECO, Spain. The author also acknowledge the COST Actions CM1401 “Our Astrochemical History” and CM1405 “Molim”.Peer Reviewe
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