127 research outputs found
Synthesis of N-(6-Arylbenzo[d]thiazole-2-acetamide derivatives and their biological activities: An experimental and computational approach
No full textA new series of N-(6-arylbenzo[d]thiazol-2-yl)acetamides were synthesized by C-C coupling methodology in the presence of Pd(0) using various aryl boronic pinacol ester/acids. The newly synthesized compounds were evaluated for various biological activities like antioxidant, haemolytic, antibacterial and urease inhibition. In bioassays these compounds were found to have moderate to good activities. Among the tested biological activities screened these compounds displayed the most significant activity for urease inhibition. In urease inhibition, all compounds were found more active than the standard used. The compound N-(6-(p-tolyl)benzo[d]thiazol-2-yl)acetamide was found to be the most active. To understand this urease inhibition, molecular docking studies were performed. The in silico studies showed that these acetamide derivatives bind to the non-metallic active site of the urease enzyme. Structure-activity studies revealed that H-bonding of compounds with the enzyme is important for its inhibition
اجتہاد الرسول ﷺ از نادیہ شریف العمری کا تعارفی مطالعہ: An Introductory Study of Ijtihad Al-Rasool ﷺ by Nadia Sharif Al-Omari
No full textThe biography of the Prophet ﷺ is a subject that has been extensively written about since the first century of Hijra, continues to be written about today, and will undoubtedly remain a topic of scholarly and devotional interest in the future. This subject holds religious, academic, historical, and contemporary significance, prompting Muslim scholars of every era to contribute to its exploration. Alongside men, women have also engaged in writing on this subject to express their devotion and love for the Prophet ﷺ. From ancient to modern times, women have played their part in this field, and while their contributions are fewer in comparison to men, their numbers are steadily increasing in modern times. Women have also explored various aspects of the Prophet's ﷺ biography in the Arabic language. One notable work in this context is "Ijtihad Al-Rasool" authored by Nadia Sharif Al-Omari. This book uniquely combines the principles of Islamic jurisprudence (Usul al-Fiqh) with the life of the Prophet ﷺ, analyzing whether the Prophet ﷺ engaged in ijtihad (independent reasoning). The author meticulously presents evidence supporting her conclusion that the Prophet ﷺ did indeed engage in ijtihad. This article provides a research-based and analytical study of her book. It begins by discussing the biographical details of the author, followed by an introduction to the book. Subsequently, the writing style of the author and the nuanced insights within her work are critically examined. Finally, the findings and recommendations of the study are presented.
Fatigue of woven thermoplastic composites: The effect of the fibre-matrix interface
No full textSI&CAerospace Engineerin
GUI implementation of image encryption and decryption using Open CV-Python script on secured TFTP protocol
No full textCoaching 5.0, coaching for the fifth industrial revolution
No full textThe rising use of Artificial Intelligence (AI), Metaverse and Blockchain technologies has influenced capabilities in a wide variety of industries. These have now started to provide affordances for automating provision of insight and empowerment in coaching business leaders and staff. This paper discusses the risk, that as such technologies become smarter, human beings may abdicate their thinking capabilities, especially related to creative problem solving, to machine intelligence. The author calls for prevention of cognitive decline in human beings as machines get smarter. A route to this can be mapped through use of Industry 5.0, Fifth Industrial Revolution (5IR) approaches, that focus on a harmonisation of human and machine intelligence, ensuring human beings can make machines smarter and that machine intelligence can in turn make human consciousness advance. Practitioner Coaches, to future proof their practice, must ensure they embody 5IR mindsets, techniques and technologies. The coaching discipline that is fit for practice in 5IR environments and contexts is what the author has called “Coaching 5.0.” This paper looks at Coaching 5.0 components and how they can be adopted by coaches to ensure the future is sustainable, insightful and empowering one for their practice and for their clients
Assessment of Air Pollution and its Effects on Health of Workers of Steel Re-Rolling Mills in Hyderabad
No full textThe SRRMs (Steel Re-Rolling Mills) are being releasing air pollutants in the environment. In order to evaluate their effect on the health of the workers, health and safety issues were analyzed by first measuring the concentrations of SO x (OIxides of Sulphur), NO x (Oxides of Nitrogen), CO (Carbon Monoxide) and O2 (Oxygen) produced in the three SRRMs located in SITE area Hyderabad. The mean concentration of SO x , NO x and CO were in the order of 0.35, 0.280, 6.333 ppm, respectively, whereas the mean concentration of O 2 was 203.53 thousand ppm. As per results, the concentration ofair pollutants, including SOx and NO x were significantly higher than to the NEQS (National Environmental Quality Standards) and NAAQS (National Ambient Air Quality Standards). The concentration ofCO was lower than to the NAAQS, but higher than to the NEQs, while the concentration of O2 was slightly lower than to the standard value. The workers who were exposed to these air pollutants are being suffering from chronic diseases related to breathing and allergies. Moreover, labour staff was lifting heavy loads manually, which causes them to muscular and joint problems. In all the SRRMs under study, the electrical and mechanical equipments were used without any safety. The MSDS were not displayed on the workstations, the housekeeping was inadequate and most of the workers were performing their jobs without personal protective equipment. In addition to these, the other serious issues related to the occupational health and safety were an unhygienic
supply of water, higher noise level, placement of explosive cylinders in the open atmosphere and
unavailability of the first aid facilities in the Mill premises
Relationship between sexual harassment at workplace and subjective well-being among working women in South Punjab, Pakistan
No full textSexual Harassment at workplace (SHW) is a global phenomenon. However, there has been no prior research on the association of SHW and subjective well-being (SWB) of working women in Pakistan. The SWB is an umbrella term that encompasses concepts such as satisfaction with life (SWL) and subjective happiness (SbH). The 200 working women from the public and private sector organizations in Pakistan were recruited randomly. The Sexual Harassment Experience Questionnaire, The Satisfaction with Life Scale, and Subjective Happiness Scale were administered as the main measures. The study met all the ethical considerations. The data was analyzed by the Statistical Package for the Social Sciences and expressed as baseline characteristics, correlation analysis and t tests. There was statistically significant negative relationship of SHW with SWL and SbH in working women. The young age, high school or less education, single marital status, and working in private sector organization were significantly associated with the increased and decreased experience of SHW and SWB respectively. The study recommended the adoption of anti SHW laws by the working sector and the periodic screening of working women for SWB so as to reduce the phenomenon of SHW and enhance the SWL and SbH in working women
Remote Sensing and GIS Based wheat Crop Acreage and Yield Estimation of District Hyderabad, Pakistan
No full textPre-harvest reliable and timely yield forecast and area estimates of cropped area is vital to planners and policy makers for making important and timely decisions with respect to food security in a country. The present study was conducted to estimate the wheat cropped area and crop yield in Hyderabad District, Pakistan from the Landsat 8 satellite imagery for Rabi 2013-14 and ground trothing. The required imagery of district Hyderabad was acquired from GLOVIS and was classified with maximum likelihood algorithm using ArcGIS 10.1. The classified image revealed that in district Hyderabad wheat covered 10,210 hectares (9.74% of total area) during Rabi season 2013-14 against 15,000 hectares (14.3% of total area) reported by Crop reporting Services (CRS), Sindh which is 30% less than that of reported by CRS. A positive linear relation between the wheat crop yield and the peak NDVI with coefficient of determination R2 = 0.91 was observed. Crop area and yield forecast through remote sensing is easy, cost effective, quick and reliable hence this technology needs to be introduced and propagated in the concerned government departments of Pakista
Uncertainty in Fiscal and Monetary Policy and its Impact on Economic Growth: An Analysis from Pakistan
No full textUncertainty or shocks in macroeconomic policies have been a debated issue all over the world because these shocks severely influence the growth of economies. To analyze the impacts of these shocks in the context of Pakistan, the current study determined the role of fiscal and monetary policy uncertainty by taking the time series data for the period 1971-2020. In this regard, GARCH and ARDL cointegration model were applied. Empirical evidence revealed that in the long-run, fiscal uncertainty in terms of government expenditure positively affects the economy and monetary uncertainty in terms of money supply negatively affects the economy. While, in the short-run, uncertainty of both policies has a negative influence on the economic growth of Pakistan. The study also gauged other factors, such as, exchange rate, interest rate, and inflation with respect to their impact on economic growth. It was found that these factors positively and significantly sway growth in the long-run
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