1,591 research outputs found
Scientific methodology. Analytical observational studies
No full text20.500.12530/87855Observational and analytical epidemiological studies are those that allow the study of causal relationships and associations between variables, without the researcher assigning or introducing the study factor into the sample. That is, the researcher limits himself to observing how an exposure gives rise to an outcome. There are different types of observational studies, some prospective and others retrospective. In this article we will see some of the most common designs, such as the cohort study and the case-control study
Análisis de las medidas de adiposidad, de glucemia y componentes del síndrome metabólico con la rigidez arterial en sujetos con riesgo cardiovascular intermedio. Estudio Mark.
No full text[ES]Los objetivo de mi tesis doctoral son:
1.Analizar si la asociación entre el CAVI y parámetros de estructura y función vascular en adultos es independiente del RCV y del tratamiento farmacológico utilizado.
2. Analizar la relación existente entre el síndrome metabólico y sus componentes con la rigidez arterial, medida con la VOP brazo tobillo y con el CAVI, en adultos de raza caucásica con RCV intermedio y analizar las diferencias por género.
3. Analizar la relación existente entre la glucemia plasmática en ayunas, la glucemia postprandial y la HbA1c con la rigidez arterial, medida con la VOP brazo tobillo y con el CAVI, en adultos de raza caucásica con RCV intermedio y analizar esta relación según el status de hiperglucemia.
4. Analizar la relación de diferentes medidas de adiposidad con la rigidez arterial, medida con la VOP brazo tobillo y con el CAVI, en adultos de raza caucásica con RCV intermedio y determinar qué medida tiene mayor poder explicativo de la rigidez arterial.
Para dar respuesta a los mismo se ha realizado un estudio trasversal con los sujetos incluidos en el estudio MARK. Cada uno de los objetivos ha sido pulicado en un manuscrito en revistas de 1 y 2 cuartil. Los manuscritos publicados son:
1. Gomez-Sanchez L, Garcia-Ortiz L, Patino-Alonso MC, Recio-Rodriguez JI, Frontera G, Ramos R, Martí R, Agudo-Conde C, Rodriguez-Sanchez E, Maderuelo-Fernandez JA and Gomez-Marcos MA. The association between the Cardio-ankle Vascular Index and Other Parameters of Vascular Structure and Function in Caucasian Adults: MARK Study. J Atheroscler Thromb 2015; (22):901-911.
2. Gomez-Sanchez L, Garcia-Ortiz L, Patino-Alonso MC, Recio-Rodriguez JI, Rigo F, Martí R, Agudo-Conde C, Rodriguez-Sanchez E, Maderuelo-Fernandez JA, Ramos R, Gomez-Marcos MA and the MARK Group. Association of metabolic syndrome and its components with arterial stifness in Caucasian subjects of the MARK study: a cross-sectional trial. Cardiovascular Diabetology 2016; 15(148):1-12.
3. Gomez-Sanchez L, Garcia-Ortiz L, Patino-Alonso MC, Recio-Rodriguez JI, Feuerbach N, Martí R, Agudo-Conde C, Rodriguez-Sanchez E, Maderuelo-Fernandez JA, Ramos R, Gomez-Marcos MA, for the MARK Group. Glycemic markers and relation with arterial stiffness in Caucasian subjects of the MARK study. Plos One 2017; 17:1-17.
4. Gomez-Sanchez L, Garcia-Ortiz L, Patino-Alonso MC, Recio-Rodriguez JI, Rigo F, Martí R, Agudo-Conde C, Rodriguez-Sanchez E, Maderuelo-Fernandez JA, Ramos R, Gomez-Marcos MA, for the MARK Group. Adiposity
measures and arterial stiffness in primary care: the MARK prospective observational study. BMJ Open 2017; 7:e016422.
Las conclusiones principales son:
1ª La asociación positiva del CAVI con los parámetros de estructura y función vascular es independiente del RCV y tratamiento farmacológico realizado. La capacidad del CAVI para predecir arterioesclerosis carotidea es similar a la de la VOP carótida femoral y a la de la VOP brazo tobillo en adultos de raza caucásica.
2ª El síndrome metabólico y la mayor parte de sus componentes se asociaron con la VOP brazo tobillo y con el CAVI, (excepto el colesterol HDL con la VOP brazo tobillo y con el CAVI y la circunferencia de la cintura con la VOP brazo tobillo). Sin embargo, esta asociación es diferente por género. Los datos sugieren una mayor asociación de los valores del CAVI y de la VOP brazo tobillo con los componentes del SM en hombres que en mujeres. También indican una mayor rigidez arterial cuando los componentes que se asocian para definir el SM fueron la presión arterial, la glucemia en ayunas y la circunferencia de la cintura elevada.
3ª La glucemia basal, glucemia postprandial y HbA1c muestran asociación con el CAVI y con la VOP brazo tobillo, independiente de otros factores de confusión en adultos de raza caucásica con RCV intermedio. En el análisis por estatus de hiperglucemia, la asociación sólo se mantiene en los sujetos con diabetes mellitus tipo 2.
4ª Las medidas de adiposidad analizadas muestran una asociación negativa con las medidas de rigidez arterial. El porcentaje de variación del CAVI explicado por su relación con las diferentes medidas de adiposidad oscila entre el 5,8% con el CUN-BAE y el 3,7% con el BRI. En el caso de VOP brazo tobillo oscila entre 0,7% con el CUN-BAE e IMC y 0,1% con la CCA. Estos resultados sugieren que las medidas de adiposidad general y porcentaje de grasa corporal explican mejor la variabilidad del CAVI en comparación con las medidas de adiposidad abdominal y visceral
Comments on “what is the radiation before 5G? A correlation study between measurements in situ and in real time and epidemiological indicators in Vallecas, Madrid”
No full textNajera A, Ramis R, Las-Heras Andes F, Garcia-Pardo C, Alonso JI, Gonzalez-Rubio J, Hernando A, Martinez JL, Marcos F
Improved protection of glutathione by the formation of inclusion complexes with α-cyclodextrin
No full textNew delivery systems combining cyclodextrins and polymers: application to the oral administration of glutathione
No full textIaía Garcia, Esaú e Jacó e Memorial de Aires : a construção de um narrador
No full textEste trabalho tem como objetivo principal o estudo do narrador no romance Memorial de Aires, de Machado de Assis. Em uma primeira etapa buscou-se levantar a fortuna crítica do romance, conforme algumas interpretações para se chegar a uma análise do narrador machadiano. No segundo momento foram revisitados desse autor os romances Iaiá Garcia, Esaú e Jacó e o conto Galeria Póstuma, procurando compreender a importância dos personagens Luís Garcia, conselheiro Aires e Joaquim Fidélis, base para a constituição do narrador do Memorial de Aires. Para isso, verificou-se pela comparação que Machado de Assis configurava tipos semelhantes ao conselheiro Aires, dos romances Esaú e Jacó (1904) e Memorial de Aires (1908), através dos personagens Luís Garcia, do romance Iaiá Garcia (1879) e Joaquim Fidélis, do conto Galeria Póstuma (1883-1884). Quem é o conselheiro Aires que figura como personagem e narrador? Ele é um narrador dissimulado? A dissertação mergulha nos quatro textos para responder as questões pelo estudo do narrador do Memorial de Aires.The main subject of the present work is studying the narrator of Memorial de Aires, written by Machado de Assis. On a first stage it was aimed to bring up the critical wealth of the novel, according to some interpretations, in order to reach after an analysis of this Machado’s narrator. At a second moment the novels of the same author, Iaiá Garcia, Esaú & Jacó and the tale Galeria Póstuma, have been looked up again, trying to understand the magnitude of the named personages Luis Garcia, counselor Aires and Joaquim Fidélis, on whom the constitution of the narrator of Memorial de Aires was based. Therefore, it has been verified that Machado de Assis set similar types to Counselor Aires, of the novels Esaú & Jacó (1904) and Memorial de Aires (1908), since the first phase through de personage Luís Garcia, of the romance Iaiá Garcia (1879) and Joaquim Fidélis, of the tale Galeria Póstuma (1883-1884). Who finally is counselor Aires, appearing as personage and as narrator? Is he an underhanded narrator? This essay dives into the four texts aiming to answer the question by studying the narrator of Memorial de Aires
Milky Rust
No full textMilky Rust is a translation by the author of his original poem that is called Óxido lácteo. This poem was included in the anthology that #LdeLírica-Ámbito Cultural and Huerga y Fierro Press published in Spain in 2022. The author of the original poem, Marcos García Barrero, was one of the finalists in the National Poetry Competition III National Award for Performance Poetry (III Premio Nacional de Poesía viva #LdeLírica.
Improved protection of glutathione by the formation of inclusion complexes with α-cyclodextrin
No full textThe localization of GSH and SBE7m 7m-β-CD inside the NPs was identified by X-ray photoelectron spectroscopy (XPS)
Exploring cross-lingual word embeddings for the inference of bilingual dictionaries
No full textPaper included in:
Proceedings of TIAD-2019 Shared Task – Translation Inference Across Dictionaries
co-located with the 2nd Language, Data and Knowledge Conference (LDK 2019)
Leipzig, Germany, May 20, 2019.[Abstract]: We describe four systems to generate automatically bilingual
dictionaries based on existing ones: three transitive systems differing only
in the pivot language used, and a system based on a different approach
which only needs monolingual corpora in both the source and target
languages. All four methods make use of cross-lingual word embeddings
trained on monolingual corpora, and then mapped into a shared vector space. Experimental results confirm that our strategy has a good
coverage and recall, achieving a performance comparable to to the best
submitted systems on the TIAD 2019 gold standard set among the teams
participating at the TIAD shared task.Research supported by a 2017 Leonardo Grant for Researchers and Cultural Creators (BBVA Foundation), by Ministerio de Economía, Industria y Competitividad (Grant TIN2017-85160-C2-1-R), and by Xunta de Galicia (Grant ED431B-2017/01). Marcos Garcia has been funded by a Juan de la Cierva grant (IJCI-2016-29598), and Marcos García-Salido by a post-doctoral grant from Xunta de Galicia (ED481D 2017/009).
We gratefully acknowledge the support of NVIDIA Corporation with the donation of the Titan Xp GPU used for this research.Xunta de Galicia; ED481D 2017/009Xunta de Galicia; ED431B-2017/0
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