1,721,044 research outputs found

    Single Nucleotide Polymorphisms in CD14 and Toll-like Receptor 4 Genes in Patients with Polycystic Ovarian Syndrome

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    ABSTRACT Introduction Polycystic ovary syndrome (PCOS) is a complex disease having genetic, immunologic, and environmental components, and candidate genes on innate immunity have been hypothesized to be involved in its etiology. We examined the possible association of CD14 and toll-like receptor 4 (TLR4) polymorphisms with PCOS. Materials and methods A total of 219 women with PCOS and 272 healthy women were recruited in the study. Their samples were genotyped for the polymorphism of CD14 and TLR4 genes. Results The distributions of genotypes of both polymorphisms were found to be significant in women with PCOS compared with controls. The distributions of alleles were also found to be predominant in PCOS compared with controls. Conclusion Polymorphisms in CD14-159C&gt;T and TLR4-299A&gt;G significantly increased susceptibility to PCOS. Further studies with larger sample sizes are warranted to confirm these findings. How to cite this article Allauddin N, Rozati R. Single Nucleotide Polymorphisms in CD14 and Toll-like Receptor 4 Genes in Patients with Polycystic Ovarian Syndrome. J South Asian Feder Obst Gynae 2017;9(4):304-307. </jats:sec

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    The impact of dividend policy on shareholders' wealth: evidence on Malaysia’s plantation listed companies performance / Muhammad Azmi Khir Allauddin

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    Dividend policy is one of the most controversial subjects in finance and dividend is always unpredictable in the residual policy due to the dividend is keeping growing followed by years. There is no consensus among researchers about the impact of dividend policy on share price. The objective of this research paper is to determine the impact of dividend policy on shareholders' wealth in Malaysia's food producer sector which is Malaysian plantation companies. By taking five independent variables (dividend pay-out ratio, earning volatility, growth in assets, liquidity and profitability) and companies performance as dependent variable which represented by the earnings per share. This research paper is aimed at analyzing Factors That Affecting Dividend policy On Companies Performance which focuses on Malaysian plantation sector. For this purpose, a sample of 8 companies from Malaysian plantation companies listed in main market Bursa Malaysia was selected. This research paper is applying multiple regressions for a period of 6 years from 2008 - 2013 Thus, the total number of observations is 46 after doing some changes. In this research, the data was collected in term of secondary data which taken from the sources of Thomson Reuters DataStream. In this research, panel data are used. Panel data is the method with the combination of cross sectional data and time series data. There are 44 companies in Malaysia's listed in plantation sector. However, the total of 8 was companies chosen in this research due to the not available data or information as well as there are no dividend pay-out s between the research periods which are between years 2008 to year 2013

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    Characterization of novel thermophilic microorganisms from hot springs / Zuridah Hassan, Zeenathul Nazariah Allauddin and Rahizan Issa

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    Introduction: Thermophilic bacteria can be isolated at high temperatures (60°C to 80°C) in hot springs of neutral or alkaline pH, as well as in hot water or in natural waters subjected to thermal population. This is in contrast to mesophiles which normally survive at 37°C. Objective: To isolate and characterize thermophilic bacteria from the hot springs in Malaysia and to identify useful products from these bacteria. Materials and Methods: Water samples from six hot springs (Selayang, Setapak, Klah, Labis, Gadek, and Pedas) were collected using the LaMotte bottom sampling dredge and transported in cold boxes back to the laboratory at UiTM. Portions of these water samples were mixed with CTYE medium and another portion without CTYE medium and were incubated at 60°C for 1 to 2 days. After 24 h incubation, turbid samples were plated and incubated at the same temperature using 3% agar in CTYE medium. Pure colonies were chosen from each culture plate for identification by (i) conventional biochemical methods and (ii) molecular characterization. DNA were extracted from positive cultures and amplified for 16S rDNA gene by polymerase chain method. The amplicons were sent for sequencing and results obtained were aligned with representative 16S rDNA sequences of related taxa using CLUSTAL W 1.83 software. Reference strain Thermus aquaticus (ATCC® 25104™) was included as control. Results: Most of the organisms from the hot springs can be maintained in the laboratory using CTYE medium at 60°C. The water temperature ranged from 48°C to 95°C with pH 6.8 to 7.9. By conventional tests and microscopic examination, five new strains of bacteria (Klah, Klah 2, Labis, Gadek, and Pedas) were isolated and confirmed to be closely related to Geobacillus spp. These bacteria were Grampositives, motile, oxidase and catalase positive. In these same locations, another four Gr$m negative bacilli (Sly, Sly 2, Klah 1, and Gadek 1) and three Gram-positive spore-forming bacilli (Sly 1, Klah 3, Gadek 2) were also found. Out of the four Gramnegatives, two strains (Gadek 1 and Klah 1) were found to be closely related to Thermus strains. All the Gram-positives were related to thermophilic Bacillus spp. Based on 16S rDNA study, five new strains of bacteria (Klah, Klah 2, Labis, Gadek, and Pedas) were confirmed to be closely related to Geobacillus spp. (Gram-positive bacilli, motile, oxidase and catalase positive). By skim milk test, five strains (Gadek, Gadek2, Labis, Klah3, and Klah2) were suspected to be protease producers out of eight thermophiles (Gadek, Gadek2, Labis, Pedas, Klah3, Klah2, Sly, and Slyl) tha
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