134,466 research outputs found
Efficacy of dienogest in improving pain in women with endometriosis : a 12-month single-center experience
No full textPurpose: Dienogest has recently been marketed as a medical treatment for endometriosis. Given the recent introduction on the market of Dienogest, little data are available regarding its effectiveness in routine clinical practice. Methods: The study is an observational, single-center, cohort study. Eligible was women with a surgical diagnosis of endometriosis dating back <24 months or a clinical/instrumental diagnosis of endometriosis and endometriosis-associated pelvic pain score of at least 40 mm on a 100-mm visual analog scale (VAS) at start of treatment and who had been taking Dienogest 2 mg once daily treatment at the time of study entry for no more than 30 days, consecutively observed between September 2013 to September 2014. In accordance with routine practice, women came back for clinical assessment and evaluation of pain after 1 (V1), 3 (V2), and 12 (V3) months. Results: A total of 132 women were enrolled in the study. A total of 21 of the enrolled patients were released from the study during follow-up due to adverse effects. The mean pelvic pain VAS score at baseline was 8.9 (SD 1.3). The corresponding values were 6.7 (SD 3.2) and 5.7 (SD 3.7) for dyspareunia and dyschezia. The mean VAS scores progressively and significantly decreased to 0.9 (SD 1.6) for pelvic pain, 1.4 (SD 2.1) for dyspareunia and 0.2 (SD 0.9) for dyschezia, respectively, 12 months after start of treatment. Conclusion: This study confirms that in routine clinical practice, Dienogest 2 mg is an effective and well-tolerated treatment for endometriosis-related pain in women with endometriosis
Refractive surgical correction and treatment of keratoconus
No full textKeratoconus is an ectatic corneal disorder that causes severe vision loss. Surgical options allow us to correct, partially or totally, the induced refractive error. Intracorneal ring segments (ICRS) implantation represents a minimally invasive surgical option that improves visual acuity, with a high success rate and a low overall complication rate. Corneal allogenic ICRS consists of ring segments derived from allogenic eye bank-processed donor corneas. Selective topography-guided transepithelial photorefractive or phototherapeutic keratectomy combined with CXL is another way in selected cases to improve spectacles corrected distance visual acuity. The microphotoablative remodeling of the central corneal profile is generally planned by optimizing the optical zones and minimizing tissue consumption. Phakic intraocular lens (PIOL) implant is considered in patients with stable disease and acceptable anatomical requirements. The two types of pIOLs, depending on their implantation inside the eye, are anterior chamber-pIOLs, which fixate to the anterior surface of the iris by using a polymethomethacrolate claw at the two haptics, and posterior chamber-pIOLs. In patients with both cataracts and keratoconus, the correct IOL power is difficult to obtain due to the irregular corneal shape and K values. Toric IOL is recommended, but carefully judging the topography and the possible need of subsequent keratoplasties
Refractive Surgical Correction and Treatment of Keratoconus
No full textKeratoconus is an ectatic corneal disorder that causes severe vision loss. Surgical options allow us to correct, partially or totally, the induced refractive error. Intracorneal ring segments (ICRS) implantation represents a minimally invasive surgical option that improves visual acuity, with a high success rate and a low overall complication rate. Corneal allogenic ICRS consists of ring segments derived from allogenic eye bank -processed donor corneas. Selective topography -guided transepithelial photorefractive or phototherapeutic keratectomy combined with CXL is another way in selected cases to improve spectacles corrected distance visual acuity. The microphotoablative remodeling of the central corneal profile is generally planned by optimizing the optical zones and minimizing tissue consumption. Phakic intraocular lens (PIOL) implant is considered in patients with stable disease and acceptable anatomical requirements. The two types of pIOLs, depending on their implantation inside the eye, are anterior chamber-pIOLs, which fixate to the anterior surface of the iris by using a polymethomethacrolate claw at the two haptics, and posterior chamber-pIOLs. In patients with both cataracts and keratoconus, the correct IOL power is difficult to obtain due to the irregular corneal shape and K values. Toric IOL is recommended, but carefully judging the topography and the possible need of subsequent keratoplasties
Sporcularda kas mekanik özelliklerinin plantar bas nç da l m yla ili kisinin incelenmesi
No full textAmaç: Sporcularda kas mekanik özelliklerinin plantar bas nç da l m yla ili kisinin incelenmesidir. Yöntem: Ara t rmaya 20,28 ± 2,10 ya ortalamas olan farkl spor bran lar na sahip 58 erkek sporcu gönüllü olarak kat lm t r. lk olarak kat l mc lar n kas mekanik özellikleri biceps femoris (BF) kas üzerinden de erlendirilmi tir. De erlendirme MyotonPro kas palpasyon cihaz kullan larak; tonus (T), sertlik (S) ve elastikiyet (E) parametreleri ile yap lm t r. Daha sonra kat l mc lar n plantar bas nç da l m özellikleri P-WALK baropodometre cihaz yard m yla parmaklar (P), metatarsal bölge (MB), ark bölgesi (AB), topuk bölgesi (TB) ve ark indeksi (A ) parametreleriyle de erlendirilmi tir. De i kenler aras ndaki ili ki istatiksel olarak analiz edilmi tir. Bulgular: De i kenler aras ndaki ili ki incelendi inde; sa tonus (SA T) ile sa ayak aras nda; P parametresinde negatif yönde, AB parametresinde pozitif yönde, sol tonus (SOLT) ile sol ayak aras nda AB parametresinde, SOLT ile sa ayak aras nda TB parametresinde pozitif yönde anlaml ili ki oldu u görülmü tür. Sa sertlik (SA S) ile sa ayak aras nda P parametresinde negatif yönde, AB parametresinde pozitif yönde, sol sertlik (SOLS) ile sol ayak aras nda AB parametresinde, SOLS ile sa ayak aras nda TB parametresinde pozitif yönde anlaml ili ki oldu u görülmü tür. Sa elastikiyet (SA E) ile sa ayak aras nda P parametresinde negatif yönde, A parametresinde pozitif yönde anlaml ili ki oldu u görülmü tür. Sonuç: Ara t rman n sonuçlar na göre kas mekanik özellikleri ile baz plantar bas nç da l m parametreleri aras nda anlaml ili kiler oldu u görülmü tür. Bu sonuçlar, plantar bas nçta gözlenen de i imlerin, yaln zca yerel yüklenmelerin sonucu olmad n proksimal kas gruplar ndaki mekanik özelliklerle de ili kili olabilece ini göstermektedir
Evaluation of serum CA 125 levels in patients with pelvic pain related to endometriosis
No full textThe aim of the study was to investigate the clinical value of the serum CA 125 level for diagnosing and determining the severity of endometriosis and pelvic pain associated with endometriosis. Eighty-six women who underwent operative laparoscopy were enrolled. Sixty-nine women with endometriosis and 17 without endometriosis participated in this study. In all of the patients, endometriosis was diagnosed and classified into stages according to the Revised American Fertility Society (R-AFS) classification. The mean serum CA 125 levels were determined in each patient. We also investigated the relationship between serum CA 125 concentration and the intensity of dysmenorrhea and dyspareunia in the study group. The mean serum CA 125 levels of women with endometriosis were higher than those of the control group (p35 U/mL was elevated in the subgroups with severe dyspareunia and severe dysmenorrhea versus the asymptomatic subgroup but the differences had no statistical significance. In conclusion, CA 125 serum levels were related to endometriosis and R-AFS score in the evaluated patient series. No correlation was found between serum levels of CA 125 and pelvic pain in patients with endometriosis
L"aliud pro alio"
No full textLa nozione di aliud pro alio viene analizzata nella sua origine giurisprudenziale al fine di delineare i criteri di indentificazione della categoria e i confini rispetto alla altre fattispecie di anomalie. In particolare, si analizza la disciplina e le varie fattispecie alle quale può essere estesa, con riferimento alla tendenza ad un ampliamento della categoria nelle elaborazioni dottrinali e nella prospettiva di una unificazione delle diverse fattispecie di anomalie in una categoria unitaria
M. Ioan. Christoph Kiesevvetter, Ill. Gymnasii Wilhelmo-Ernestini Rector L B S D. Non alio magis pietatis adfectu universi ad obeunda munia obstringimur ...
No full textM. IOAN. CHRISTOPH KIESEVVETTER, ILL. GYMNASII WILHELMO-ERNESTINI RECTOR L B S D. NON ALIO MAGIS PIETATIS ADFECTU UNIVERSI AD OBEUNDA MUNIA OBSTRINGIMUR ...
M. Ioan. Christoph Kiesevvetter, Ill. Gymnasii Wilhelmo-Ernestini Rector L B S D. Non alio magis pietatis adfectu universi ad obeunda munia obstringimur ... ([1]gef)
Cover ( - )
Text ([1]gef
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?
No full textIn this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
- …
