1,609 research outputs found

    Memoranda exchanged between Alfred Blalock and Sam P. Asper, September 15, 1948

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    Memoranda between Doctors Alfred Blalock and Samuel P. Asper of Johns Hopkins Hospital, in discussion of gathering cases for cardiac research with Dr. Horace Smithy. Both memoranda mention Smithy's decline in health

    The television work of Alfred Hitchcock

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    The thesis uses close textual analysis to study and evaluate the television work of Alfred Hitchcock. The corpus consists of the twenty shows personally directed by Hitchcock, including his appearances before and after those shows. In response to most previous writing, which tends to compare the programmes with Hitchcock’s films (often unfairly) the thesis emphasises them as products of television. Programmes are evaluated on the basis of their perceived success as television- if they harness conditions related to television production and integrate them with narrative themes or to create meaning. Hitchcock is considered to be the major creative force in each programme. Chapter One provides a variety of important contexts including a brief history of US television of the 1950s, key literature on Hitchcock and analyses of contemporaneous programmes not directed by Hitchcock. The textual analysis chapters (2-8) consider aesthetic or thematic programme aspects. Chapter Two studies the various roles played by Hitchcock’s appearances as series host. Chapter Three considers the impact of censorship on programmes frequently dealing with murder, violence and insanity. Chapter Four analyses Hitchcock’s implementation of varieties of voice-over narration, a common device in short dramatic forms. Chapter Five studies Hitchcock’s use of point-of-view shots, particularly in relation to their role in the delivery of the narrative twist. Chapter Six considers the key Hitchcock theme of detachment from the world. Chapter Seven looks at moments from the programmes which demonstrate how aesthetic is influenced by television production conditions. Hitchcock created a number of television masterpieces. His achievements in television are in many ways comparable in quality and consistency to his theatrical films. Even when considered in the context of other 1950s US anthology dramas, the Hitchcock-directed programmes are superior on many levels. Elements of his film style were highly suited to television production. Many of his greatest achievements embrace and harness television production conditions in their presentation strategies to create an integration of style and meaning

    The effectiveness of interventions to treat severe acute malnutrition in young children: a systematic review

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    Severe acute malnutrition (SAM) arises as a consequence of a sudden period of food shortage and is associated with loss of a person’s body fat and wasting of their skeletal muscle. Many of those affected are already undernourished and are often susceptible to disease. Infants and young children are the most vulnerable as they require extra nutrition for growth and development, have comparatively limited energy reserves and depend on others. Undernutrition can have drastic and wide-ranging consequences for the child’s development and survival in the short and long term. Despite efforts made to treat SAM through different interventions and programmes, it continues to cause unacceptably high levels of mortality and morbidity. Uncertainty remains as to the most effective methods to treat severe acute malnutrition in young children.ObjectivesTo evaluate the effectiveness of interventions to treat infants and children aged &lt; 5 years who have SAM.Data sourcesEight databases (MEDLINE, EMBASE, MEDLINE In-Process &amp; Other Non-Indexed Citations, CAB Abstracts Ovid, Bioline, Centre for Reviews and Dissemination, EconLit EBSCO and The Cochrane Library) were searched to 2010. Bibliographies of included articles and grey literature sources were also searched. The project expert advisory group was asked to identify additional published and unpublished references.Review methodsPrior to the systematic review, a Delphi process involving international experts prioritised the research questions. Searches were conducted and two reviewers independently screened titles and abstracts for eligibility. Inclusion criteria were applied to the full texts of retrieved papers by one reviewer and checked independently by a second. Included studies were mapped to the research questions. Data extraction and quality assessment were undertaken by one reviewer and checked by a second reviewer. Differences in opinion were resolved through discussion at each stage. Studies were synthesised through a narrative review with tabulation of the results.ResultsA total of 8954 records were screened, 224 full-text articles were retrieved, and 74 articles (describing 68 studies) met the inclusion criteria and were mapped. No evidence focused on treatment of children with SAM who were human immunodeficiency virus sero-positive, and no good-quality or adequately reported studies assessed treatments for SAM among infants &lt; 6 months old. One randomised controlled trial investigated fluid resuscitation solutions for shock, with none adequately treating shock. Children with acute diarrhoea benefited from the use of hypo-osmolar oral rehydration solution (H-ORS) compared with the standard World Health Organization-oral rehydration solution (WHO-ORS). WHO-ORS was not significantly different from rehydration solution for malnutrition (ReSoMal), but the safety of ReSoMal was uncertain. A rice-based ORS was more beneficial than glucose-based ORSs, and provision of zinc plus a WHO-ORS had a favourable impact on diarrhoea and need for ORS. Comparisons of different diets in children with persistent diarrhoea produced conflicting findings. For treating infection, comparison of amoxicillin with ceftriaxone during inpatient therapy, and routine provision of antibiotics for 7 days versus no antibiotics during outpatient therapy of uncomplicated SAM, found that neither had a significant effect on recovery at the end of follow-up. No evidence mapped to the next three questions on factors that affect sustainability of programmes, long-term survival and readmission rates, the clinical effectiveness of management strategies for treating children with comorbidities such as tuberculosis and Helicobacter pylori infection and the factors that limit the full implementation of treatment programmes. Comparison of treatment for SAM in different settings showed that children receiving inpatient care appear to do as well as those in ambulatory or home settings on anthropometric measures and response time to treatment. Longer-term follow-up showed limited differences between the different settings. The majority of evidence on methods for correcting micronutrient deficiencies considered zinc supplements; however, trials were heterogeneous and a firm conclusion about zinc was not reached. There was limited evidence on either supplementary potassium or nicotinic acid (each produced some benefits), and nucleotides (not associated with benefits). Evidence was identified for four of the five remaining questions, but not assessed because of resource limitation.LimitationsThe systematic review focused on key questions prioritised through a Delphi study and, as a consequence, did not encompass all elements in the management of SAM. In focusing on evidence from controlled studies with the most rigorous designs that were published in the English language, the systematic review may have excluded other forms of evidence. The systematic review identified several limitations in the evidence base for assessing the effectiveness of interventions for treating young children with severe acute malnutrition, including a lack of studies assessing the different interventions; limited details of study methods used; short follow-up post intervention or discharge; and heterogeneity in participants, interventions, settings, and outcome measures affecting generalisability.ConclusionsFor many of the most highly ranked questions evidence was lacking or inconclusive. More research is needed on a range of topic areas concerning the treatment of infants and children with SAM. Further research is required on most aspects of the management of SAM in children &lt; 5 years, including intravenous resuscitation regimens for shock, management of subgroups (e.g. infants &lt; 6 months old, infants and children with SAM who are human immunodeficiency virus sero-positive) and on the use of antibiotics.FundingThe National Institute for Health Research Technology Assessment programme.<br/

    Izvori informacija u dostupnim EBSCO bazama podataka za istraživanja u visokom školstvu u Srbiji = Academic research in Serbia and available database resources

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    Universities in Serbia have access to large amounts of quality information through online full text databases. Specific details regarding the world’s two most comprehensive full text research data-bases, Academic Search Premier and Business Source Premier are provided. The paper examines which databases are strongest in each discipline, and covers issues such as the availability of journals most-cited, full text formats, peer-review status, embargo periods, backfills, and other important facets. Additional information depicts reasons for tremendous increase in the availability of information in the Serbia, and the value that these resources bring to researchers in universities

    SAM-Melt_EA v5.0 (R Code)

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    OverviewThe notebooks in this repository contain R code that has been used to investigate the influence of the Southern Annular Mode (SAM) on surface melt in East Antarctica.This work has been undertaken as part of my PhD with MISI and SAEF at Monash University, where I am supervised by Prof. Andrew Mackintosh, Dr. Felicity McCormack, and Dr. Richard Jones. The work has also been supported by co-author Dr. Christiaan van Dalum (IMAU, Utrecht University).This project uses output from the RACMO2.3p3 regional climate model to identify spatiotemporal variability in the SAM-Melt relationship, and to understand the physical mechanisms responsible for the relationship. An accompanying manuscript is currently under review for publication.Code & InstructionsThis project uses the R programming language and was written using RStudio, on both Windows 10 and MacOS 14.1. It uses the renv package to help with portability / replicability.The code here can also be found on GitHub in the SAM-Melt_EA repository, and is tagged as Version v5.0. See the "README.md" file on GitHub for more information about the project and the repository set-up, plus where to download the necessary raw data. In particular, it is necessary to download the RACMO2.3p3 data, available online at: https://doi.org/10.5281/zenodo.7639053.NOTE: This version of the code (v5.0) makes some minor changes to the formatting of the v4.1 figures following the first stage of the peer review process, and includes more comments and notes in the code.Note: In addition to standard R packages from CRAN, it will be necessary to install 5 packages from my GitHub page. These packages (and the version used in this project) are:polarcm (v0.1.3) eases use of output from the polar regional climate models RACMO and MARterrapin (v0.1.1) spinoff from terra that eases handling dates for spatial datafiguR (v0.1.2) for easy-to-customise figureskulaR (v0.1.5) a wrapper around khroma to ease colour management in plotsdomR (v0.1.5) functions for easing how I approach a project with R</p

    SELF-POISONING SUICIDE ATTEMPTS AMONG STUDENTS IN TEHRAN, IRAN

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    Background: This study aim was to describe the epidemiology of intentional self-poisoning among students. Subjects and methods: A cross-sectional study was conducted on self-poisoned students admitted to Loghman-Hakim Hospital in Tehran, Iran. Variables studied included age, sex, substance abuse, personal history, familial history and the immediate precipitant for the suicide attempt. Results: A total of 248 students (200 F and 48 M) studied. The mean age was 16.3±1.42 years. Self poisoning with a pharmaceutical agent was the most common attempt modality (87.5%). The most common precipitant for the suicide attempt was family conflict (54.4%), followed by romantic disappointment (29.4%). The mostcommon psychiatric disorders were adjustment disorder (84.3%). and depression (18.1%). Conclusion: The emphasis in student suicide prevention programs must be on early identification of students at risk, and appropriate treatment of episodes of psychopathology

    Disarmament in the context of the international economic order

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    This paper focuses on an economic aspect of the disarmament question: the international market of armaments. I shall explore the thesis that arms trade is an increasingly important factor in North-South economic relations, that it affects not only international trade patterns, but also through trade, domestic patterns of economic development. Research assistance for this work was provided by Michael de Mello at Columbia University. In addition to the statistical sources in the references I shall be drawing as well on the results of a UNITAR study on technology, domestic distribution and North-South relations. (1)disarmament; armament; international market; international disarmament; arms trade; arms market; north; south; North-South; international trade; international trade patterns; domestic patterns of economic development; development; domestic economy; economic development; UNITAR; domestic distribution; technology; economic order; international economic order; export; import; commodity trade; trade patterns;

    Sam Wide, Griechische und römische Religion, durchgesehen und bearbeitet von Martin P. Nilsson (Einleitung in die Altertumswissenschaft, herausgegeben von Alfred Gercke und Eduard Norden, Vierte Auflage, II. Band 4. Heft. Leipzig und Berlin 1931

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    Zielinski Th. Sam Wide, Griechische und römische Religion, durchgesehen und bearbeitet von Martin P. Nilsson (Einleitung in die Altertumswissenschaft, herausgegeben von Alfred Gercke und Eduard Norden, Vierte Auflage, II. Band 4. Heft. Leipzig und Berlin 1931. In: L'antiquité classique, Tome 2, fasc. 2, 1933. pp. 443-444

    Comparative evaluation of Glasgow Coma Score and gag reflex in predicting aspiration pneumonitis in acute poisoning

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    Nastaran Eizadi-Mood, Mahmood Saghaei, Sam Alfred, Amir Hooshang Zargarzadeh, Chanh Huynh, Farzad Gheshlaghi, Ahmad Yaraghi and Yousef Shadi Saa

    Comparison of arterial and capillary blood gas values in poisoning department assessment

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    The aim of this study was to compare simultaneously obtained arterial and capillary blood gas (CBG) values in comatose-poisoned patients presented with stable vital signs. Forty-five adult patients with a diagnosis of coma because of poisoning and stable vital signs were included in this prospective study. With respect to pH, the arterial blood gas (ABG) and CBG values correlated satisfactorily (r² = .91) and had an acceptable limit of agreements (LOAs; —0.04 to 0.06). With respect to base excess (BE), the ABG and CBG values correlated well (r² = .85), but their 95% LOAs seem too wide to allow substitution (—4.4 to 2.7). PCO₂ (r² = .61), HCO₃ (r² = .71) and PO₂ (r² = .53) correlated less reliably. A capillary PCO₂ of 51.7 mm Hg had a sensitivity of 100% and a specificity of 95.12% for detecting hypercarbia (area under the curve, 0.99; 95% Confidence Interval, 0.90-0.99; p 51.7 mm Hg.Nastaran Eizadi-Mood, Sam Alfred, Ahmad Yaraghi, Chanh Huynh and Ali Shayesteh Moghada
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