2,283 research outputs found
Estudo histológico do saco herniário de hérnias inguinais indiretas: avaliação de prevalência e dados antropométricos /
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde.A musculatura lisa presente no saco herniário de hérnias inguinais do tipo indireta de pacientes adultos do sexo masculino foi estudada quanto a prevalência em seus três terços e a relação com o tempo, lado e tamanho da hérnia, bem como a idade do paciente e seu índice de massa corpórea, visando descobrir situações que tornem o saco herniário mais ou menos apto para sua utilização como reforço da parede posterior. Ocorreram diferenças histológicas significavas apenas em sacos herniários muito pequenos, que não apresentaram musculatura lisa. Concluímos que todos os sacos herniários de hérnias inguinais do tipo indireta podem ser utilizados no estudo da validade da técnica proposta por Lázaro da Silva
Microbial enrichment culture responsible for the complete oxidative biodegradation of 3‑Amino-1,2,4-triazol-5-one (ATO), the reduced daughter product of the insensitive munitions compound 3‑Nitro-1,2,4-triazol-5-one (NTO)
No full text3-Nitro-1,2,4-triazol-5-one (NTO) is one of the main ingredients of many insensitive munitions, which are being used as replacements for conventional explosives. As its use becomes widespread, more research is needed to assess its environmental fate. Previous studies have shown that NTO is biologically reduced to 3-amino-1,2,4-triazol-5-one (ATO). However, the final degradation products of ATO are still unknown. We have studied the aerobic degradation of ATO by enrichment cultures derived from the soil. After multiple transfers, ATO degradation was monitored in closed bottles through measurements of inorganic carbon and nitrogen species. The results indicate that the members of the enrichment culture utilize ATO as the sole source of carbon and nitrogen. As ATO was mineralized to CO₂, N₂, and NH₄⁺, microbial growth was observed in the culture. Co-substrates addition did not increase the ATO degradation rate. Quantitative polymerase chain reaction analysis revealed that the organisms that enriched using ATO as carbon and nitrogen source were Terrimonas spp., Ramlibacter-related spp., Mesorhizobium spp., Hydrogenophaga spp., Ralstonia spp., Pseudomonas spp., Ectothiorhodospiraceae, and Sphingopyxis. This is the first study to report the complete mineralization of ATO by soil microorganisms, expanding our understanding of natural attenuation and bioremediation of the explosive NTO.Journal ArticleFinal article publishe
Two Saints : The martyrdom of St. Sergius & St. Bacchus.
No full textBook 1 v. (unpaged) : col. ill. ; 23 cm.'This second offering from Seven Hills Press was printed in late spring 2004. The paper is a conglomeration of cotton, abaca, and iris leaves from the garden. The cover stock has been dyed with black walnut stain provided by Lisa Beth Robinson. The typeface is primarily Garamond.' -- Colophon. Limited ed. of 35. Concertina binding with signatures stitched in.Signed by the author/printer/artist Brian Borchardt. No. 12 of a limited ed
The conflict in Yugoslavia and the world political figures
No full textBakalářská práce analyzuje ozbrojené konflikty, které proběhly v 90. letech 20. století v souvislosti s rozpadem bývalé Jugoslávie v Chorvatsku, v Bosně a Hercegovině a v Kosovu. Autorka se zaměřuje na otázku, jak se světoví političtí hráči postavili k těmto konfliktům a jak se v nich angažovali, a to před jejich vypuknutím, v průběhu, při ukončení i při následném mírovém uspořádání. Cílem práce je prokázat, že obrovská brutalita analyzovaných konfliktů byla do značné míry umožněna váhavým a nejednotným postojem světových politických hráčů.The bachelor's thesis analyzes the armed conflicts in the 90s of 20th century in relation to splitting up Yugoslavia in Chroatia, Bosnia-Herzegovina and Kosovo. The author focuses on the question how the prominent world political figures faced up to these conflicts and how they were engaged in them before the conflicts broke out, throughout them and during their final period and following peace settlement. The aim of this work is to prove that the primitive brutality of these conflicts was to a great extent caused by the reluctant and non-uniform stand of the global political figures
Utilizing V. constablaei and V. ashei in germplasm and cultivar development
No full textAn ongoing project has pursued the goal of incorporating the cold-hardiness and late bloom of V. constablaei into a form that might be suitable for northern growers. Experimentation and past research suggested that combining V. constablaei with V. ashei would allow the best aspects of both of these germplasms to be combined into a usable form. Such hybrids derive late bloom and cold-hardiness from V. constablaei as expected, and many aspects of vigor from rabbiteye, but additional characters from both parents must be optimized to produce cultivar-quality material. The first commercial product in the USDA program of this introgression is the variety ‘Nocturne’, which achieves the majority of the goals desired in combining these germplasms. ‘Nocturne’, however, is dark-fruited and is unlikely to achieve success as a mainstream cultivar. Among more advanced breeding populations, additional strategies have been implemented to enhance the recovery of commercially acceptable types. Season of ripening, bush form, cold hardiness, fertility, and fruit quality are among the issues involved in furthering the use of this material.Paper presented at NABREW Conference, Paper Session II:Breeding and Genetics, on June 25, 2014, Atlantic City, N.J
Dilemmas of democracy: challenges to parliamentary practices from the UK public and parliamentarians
No full textThe absence of a codified constitution for the United Kingdom combined with numerous parliamentary conventions often perceived as arcane unwritten rules, made the need for guidelines on parliamentary proceedings particularly acute. Thus, in the XIXth century, the initiative came from outside Parliament with aspiring parliamentarians like Albert Venn Dicey in his Introduction to the Study of the Law of the Constitution and Walter Bagehot in his English Constitution – two authoritative works on Parliament. But it also emanated from within Parliament with Erskine May, a former clerk of the House of Commons, the author of the invaluable Treatise upon the Law, Proceedings and Usage of Parliament – enlightening parliamentary procedure. MPs guides to procedure have also brought clarification and guidance to (new) members of the House. Indeed, Parliament is “a microcosm”, with its own rules and rituals. They contribute to widening the gap between Parliament and the People it represents. Unprecedented crisis – first Brexit then the Coronavirus pandemic – have stretched parliamentary practices to their limits leading to daunting challenges such as turning Parliament into a virtual or remote legislature making it more difficult for the latter to perform its key role of holding the government to account. Yet it could be an opportunity to rethink parliamentary practices while making them more accessible to the people, thus contributing to restoring trust between them without which there cannot be an effective democracy.L’absence de constitution rigide au Royaume-Uni associée à une série de conventions parlementaires, souvent perçues comme impénétrables, rendit plus impérieux encore le besoin de décryptage de la procédure parlementaire. Aussi au xixe siècle, des auteurs extérieurs au Parlement mais qui aspiraient à le rejoindre, comme A. V. Dicey avec son ouvrage Introduction to the Study of the Law of the Constitution ou W. Bagehot et son English Constitution – deux œuvres qui font autorité sur le sujet – ont contribué à éclairer la procédure parlementaire. Mais l’initiative a également été prise par des auteurs qui travaillaient pour le Parlement, comme T. Erskine May, dans son inestimable Treatise upon the Law, Proceedings and Usage of Parliament. De même, le Guide de la Procédure à destination des membres de la Chambre des Communes oriente les nouveaux membres du Parlement dans les méandres de la procédure parlementaire. En effet, le Parlement est un microcosme doté de ses propres règles et rituels. Ces derniers tendent à creuser encore davantage le fossé entre le Parlement et le Peuple qu’il représente. Des crises sans précèdent – d’abord le Brexit, puis la crise sanitaire de la Covid – ont testé les limites des pratiques parlementaires rendant plus difficile le contrôle du Parlement sur l’action du gouvernement. Cependant, ce pourrait être l’occasion de repenser les pratiques parlementaires, afin de les moderniser tout en les rendant plus accessibles aux citoyens, contribuant ainsi à rétablir la confiance entre le Peuple et le Parlement sans laquelle la démocratie ne peut fonctionner de manière efficace
Islámská revoluce v Íránu - k lepšímu nebo k horšímu?
No full textPráce se zabývá íránskou islámskou revolucí a komparativní analýzou režimů před a po revoluci, srovnává historický vývoj a vliv revolučních změn na společnost. I když není pochyb o tom, že transformace imperiální Persie v Islámskou republiku sehrála důležitou roli v překreslení geopolitické mapy širšího Blízkého východu, cílem této práce je porovnat historický vývoj Íránu během monarchie a vliv revolučních orgánů na íránskou společnost. Přes rozsáhlé množství použitých zdrojů z Íránu i zahraničí, autorka učinila veškerou snahu ke snížení účinků vlivů ať už horlivých zastánců monarchie nebo skalních revolucionářů na minimum, a umožnila faktům samotným promítnout objektivní obrázek. Cílem práce je po objektivním srovnání fakticky odpovědět na otázku, zda revoluce vedla k lepšímu či horšímu.The thesis focuses on the Islamic Revolution of Iran by a comparative analysis of the monarchy regimes before and after the Islamic Revolution of 1979. Although there is little doubt that the transformation of Imperial Iran to the Islamic Republic has played a vital catalyst in redrawing the "greater" Middle Eastern geopolitics ever since this thesis aims to compare the historical development of Iran during the monarchy and the effect of the revolutionary institutions brought on the Iranian society. Despite the extensive amount of resources used in this thesis being both from Iran and abroad, the author has made every effort to reduce the effects of the influences whether from the overzealous defenders of monarchy or the die-hard revolutionaries to a bare minimum and allow the facts on their own to project the picture through an objective lens. The goal of the thesis is for the objective research and comparison to try and provide a factual answer to the million-dollar question, whether the revolution was for better or for worse
Islámská revoluce v Íránu - k lepšímu nebo k horšímu?
No full textThe thesis focuses on the Islamic Revolution of Iran by a comparative analysis of the monarchy regimes before and after the Islamic Revolution of 1979. Although there is little doubt that the transformation of Imperial Iran to the Islamic Republic has played a vital catalyst in redrawing the "greater" Middle Eastern geopolitics ever since this thesis aims to compare the historical development of Iran during the monarchy and the effect of the revolutionary institutions brought on the Iranian society. Despite the extensive amount of resources used in this thesis being both from Iran and abroad, the author has made every effort to reduce the effects of the influences whether from the overzealous defenders of monarchy or the die-hard revolutionaries to a bare minimum and allow the facts on their own to project the picture through an objective lens. The goal of the thesis is for the objective research and comparison to try and provide a factual answer to the million-dollar question, whether the revolution was for better or for worse
The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation
No full textEukaryotic-like Ser/Thr protein kinases (ePKs) have been identified in many bacterial species, where they are known to mediate signalling mechanisms that share several features with their eukaryotic counterparts. In Mycobacterium tuberculosis, PknI is one of the 11 predicted ePKs and it has been related to bacterial virulence. In order to better understand the molecular basis of its role in mycobacterial signalling, we solved the crystal structure of the PknI cytoplasmic domain. We found that even though PknI possesses most conserved elements characteristic of Hanks-type kinases, it is degraded in several motifs that are essential for the ePKs catalytic activity. Most notably, PknI presents a remarkably short activation segment lacking a peptide–substrate binding site. Consistent with this observation and similar to earlier findings for eukaryotic pseudokinases, no kinase activity was detected for the catalytic domain of PknI, against different substrates and in various experimental conditions. Based on these results, we conclude that PknI may rely on unconventional mechanism(s) for kinase activity and/or it could play alternative role(s) in mycobacterial signalling. Database: Atomic coordinates and structure factors for the catalytic domain of M. tuberculosis PknI are in the Protein Data Bank under the accession codes 5M06 (wild-type PknI + ADP), 5M07 (PknI_C20A), 5M08 (PknI_C20A_R136A) and 5M09 (PknI_C20A_R136N).Fil: Lisa, María Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universite de Paris V; Francia. Instituto Pasteur; FranciaFil: Wagner, Tristan. Instituto Pasteur; Francia. Universite de Paris V; FranciaFil: Alexandre, Matthieu. Instituto Pasteur; Francia. Universite de Paris V; FranciaFil: Barilone, Nathalie. Instituto Pasteur; Francia. Universite de Paris V; FranciaFil: Raynal, Bertrand. Instituto Pasteur; Francia. Universite de Paris V; FranciaFil: Alzari, Pedro M.. Instituto Pasteur; Francia. Universite de Paris V; FranciaFil: Bellinzoni, Marco. Instituto Pasteur; Francia. Universite de Paris V; Franci
Analysis of the Influence of Preferential Voting on the Municipal Elections
No full textPráce se zabývá přenosem vzorců volebního chování ze sněmovních na obecní volby v roce 2010. Ve volbách do Poslanecké sněmovny se naplno projevil fenomén tzv. "křížkování čtyř kandidátů zezadu", který vznikl na základě rozličných občanských iniciativ. Využívání preferenčních hlasů se u voleb do PS PČR ukázalo jako velmi efektivní způsob, jakým mohou voliči vyjádřit svou nespokojenost s neustále se opakujícím personálním obsazením. Cílem práce je zjistit, jaký dopad měly výsledky sněmovních voleb na hlasování voličů při volbách do obecních zastupitelstev, které se konaly o pět měsíců později. Text je rozdělen do čtyř kapitol. První pokládá práci teoretický základ rozebírající většinové a poměrné systémy s důrazem na preferenční hlasování. Druhá se zaměřuje na možnosti personalizace volby u jednotlivých typů voleb do zastupitelských orgánů v ČR. Kapitola třetí je pak na pomezí mezi teoretickou a empirickou částí, v níž autor mapuje fenomén personalizace volby do PS PČR z května roku 2010. Závěrečná čtvrtá kapitola sestává z autorovy analýzy vlivu preferenčního hlasování na výsledky voleb do zastupitelstva města Přerova, jejíž výsledky pak umožní zodpovědět stanovené otázky.The bachelor thesis deals with the transmission of voting behavior patterns from elections to the Chamber of Deputies to the Municipal elections in 2010. There has been recorded an entirely new phenomenon of preferential voting for the last four candidates on the lists during the last Parliamentary elections, which had been created by Citizens' Initiative. This kind of preferential voting has proved very effective in order to show dissatisfaction with usually always the same candidates on the lists. The aim of the thesis is to find out what was the impact of the Parliamentary elections on the voting patterns in the Municipal elections that took place five months later. The text is divided into four chapters. The first one is a theoretical basis of the thesis which deals with proportional and majority systems with a focus on preferential voting. The second chapter concentrates on the personalization of the vote in various types of elections to the Czech representative bodies. The third chapter could be characterized as a bridge between theoretical and empirical part, where the author describes the phenomenon of the preferential voting in the Chamber of Deputies in May 2010. The last (fourth) chapter consists of author's analysis of preferential voting in the Prerov Municipal elections, which in the end enables to answer the questions
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