82 research outputs found
Romana Ecclesia-Cathedra Petri (Reseña)
No full textReseña del libro de Michele MACCARRONE, Romana Ecclesia-Cathedra Petri, a cura di Piero Zerbi, Raffaello Volpini, Alessandro Galuzzi, Herder («Italia Sacra. Studia e Documenti di Storia Ecclesiastica», 47 y 48), Roma 1991, I, LXXVI + 1-670 pp.; II, 671-1419 pp
Proposal of a magnetic resonance imaging follow-up protocol after cholesteatoma surgery: a prospective study
No full textBackground: Non-echo planar (EPI) diffusion-weighted (DW) MRI has become an effective tool for the follow-up after cholesteatoma surgery and decreased the rate of second-look surgeries. Objectives: To shed light on the optimal imaging follow-up protocol to detect postoperative residual or recurrent cholesteatoma. Materials and methods: 64 patients were included in this prospective study. Three different surgical procedures were considered: canal-wall-up (26 patients), canal-wall-down (20 patients), and obliterative (18 patients). The imaging follow-up protocol included non-EPI DW MRI during the following postoperative periods: 1 month, 6 months, and 1, 3, 5, and 7 years after the primary surgery. Results: MRI-positive lesions were present in 18.75% of patients. 50% of the MRI-positive findings occurred at the 1-month follow-up. The other peak of MRI positivity occurred at the 3-year follow-up. The last MRI-positive finding appeared at the 5-year follow-up. Conclusions: The timing for the imaging protocol proposed by this prospective study to detect recidivism after cholesteatoma surgery stressed the importance of performing non-EPI DW MRI for detecting residual, though rare, disease. Likewise, extending the follow-up to a least 5 years after primary surgery was also recommended to detect any recurrent cholesteatoma that would appear unlikely to be present beyond this time se
The impact of fusion imaging technique on middle ear cholesteatoma surgery. a prospective comparative study
No full textBackground: The fusion of computed tomography images with non-echo planner diffusion-weighted magnetic resonance images may overcome the limitations of each individual modality.
Objectives: This study aimed to assess the ability of the ’fusion’ technique to predict the location of middle ear cholesteatoma by evaluating Its impact on preoperative surgical planning and postoperative results.
Methodology: Eighty-three adults with cholesteatoma underwent preoperative CT scans and non-EPI-DW-MRI with or without the ‘fusion’ technique. We evaluated cholesteatoma localization in both groups, selecting the most appropriate surgical technique, and correlating it with the intraoperative
findings. Both groups were compared in terms of residual/recurrent cholesteatoma at one, six and twelve months after surgery.
Results: The ‘fusion’ technique’s sensitivity, specificity, and accuracy in predicting the location of cholesteatoma were 97.5. 97.4, and 97.5%, respectively, versus 97.59, 57.69, and 73.21% of CT alone. There was a total operators agreement after the evaluation of the ’fusion’ images with the adopted surgical technique. A statistically significant decrease in residual and recurrence cholesteatoma rates was found in group A.
Conclusions: The ’fusion’ technique provides the surgeon with the precise cholesteatoma location, guiding him in making the correct surgical decision, contributing to the decrease in postoperative residual and recurrence rates
Stress-triggered long-distance communication leads to phenotypic plasticity: The case of the early root protoxylem maturation induced by leaf wounding in arabidopsis
No full textRoot architecture and xylem phenotypic plasticity influence crop productivity by affecting water and nutrient uptake, especially under those environmental stress, which limit water supply or imply excessive water losses. Xylem maturation depends on coordinated events of cell wall lignification and developmental programmed cell death (PCD), which could both be triggered by developmental-and/or stress-driven hydrogen peroxide (H2O2) production. Here, the effect of wounding of the cotyledonary leaf on root protoxylem maturation was explored in Arabidopsis thaliana by analysis under Laser Scanning Confocal Microscope (LSCM). Leaf wounding induced early root protoxylem maturation within 3 days from the injury, as after this time protoxylem position was found closer to the tip. The effect of leaf wounding on protoxylem maturation was independent from root growth or meristem size, that did not change after wounding. A strong H2O2 accumulation was detected in root protoxylem 6 h after leaf wounding. Furthermore, the H2O2 trap N,N1-dimethylthiourea (DMTU) reversed wound-induced early protoxylem maturation, confirming the need for H2O2 production in this signaling pathway
Prospective follow up after omalizumab discontinuation in a cohort of children with severe asthma
No full textRicerche di marketing e nuovi prodotti: il lancio dei piatti pronti Fazion.
No full textIl lavoro di tesi è strutturato in due capitoli: il primo tratta in termini generali del lancio di un nuovo prodotto e le ricerche di marketing a questo connesse; nel secondo ho effettuato la ricerca sul campo per il lancio del prodotto "Primi piatti pronti" del pastificio Fazion; si tratta di una ricerca di tipo ibrido, che utilizza, cioè strumenti sia di tipo quantitativo che qualitativo
Thermal Exposure in Concrete Tunnels Subjected to Fire
No full textTo date, many fire accidents have occurred in tunnels all over the world. In the worst cases, there were catastrophic consequences with numerous human casualties and significant economic impacts. In the occurrence of such tunnel fires, besides the primary concern of saving human life, ensuring a certain level of structural integrity is also desired. Looking from the latter perspective, this thesis is focused on the fire-induced thermal exposure in concrete tunnels, aiming at coupling numerical simulations of idealized fire scenarios in computational fluid dynamics (CFD) software with the use of FEA for the analysis of structures, moving towards a performance-based approach in replacement of the currently adopted prescriptive approach. In this sense, fire imposes one of the most hazardous conditions for concrete structures, characterizing severe thermal degradation of the mechanical properties of the material. During fire exposure, steep thermal gradients are formed within the concrete structure. Those will always lead to the development of thermal stresses, the state of which being determined by several conditions (i.e. elastic modulus, thickness and supports). Besides the structural consequences of a fire, this thesis also deeply investigates the interface between a fire and the structure, which involves the interaction of three different modes of heat transfer, namely conduction, convection (related to the gas temperatures generated by a fire), and radiation (related to the radiation temperatures generated by a fire). While conduction within the solid phase regulates the amount of heat absorbed by the structure during a fire, radiation overcomes convection and becomes the primary mode of heat supply to the structure. The adiabatic surface temperature (AST) combines both the radiation and convection contributions to the total heat transfer to the structure into a single term, fully characterizing the fire phase in the structural analysis. Based on this concept, the differences between the two methodologies (i.e. prescriptive-based and performance-based) are exposed. From the prescriptive-based perspective, the development of the RWS curve and its indistinct use among protected and unprotected concrete tunnels is deeply discussed, together with the current fire resistance furnace tests. For the performance-based approach, the thermal exposure generated by two pool fire scenarios (200 MW and 30 MW) within the Piet Hein tunnel is addressed and the effects of longitudinal ventilation are highlighted.Civil Engineering | Structural Engineering | Concrete Structure
The impact of labyrinthine magnetic resonance signal alterations on the treatment of sudden sensory-neural hearing loss
No full textBackground: Sudden sensory-neural hearing loss (SSNHL), with positive findings on magnetic resonance imaging (MRI), possibly related to labyrinthine hemorrhage, is a rare condition and difficult to be diagnosed.
Objectives: We evaluated the role of MRI in detecting labyrinthine signal changes and the impact of these changes on the prognosis of SSNHL after the intratympanic corticosteroid injection.
Methods: A prospective study was held between January and June 2022. We included patients who complained of SSNHL, either idiopathic (30 patients) or labyrinthine signal alterations (14 patients), as diagnosed by MRI performed 15 days after the SSNHL onset. In addition, all patients underwent a course of intratympanic prednisolone injections.
Results: 83.3% of the idiopathic group showed a complete or marked improvement after the intratympanic injection. Conversely, most cases of positive MR signal alterations (92.8%) had slight or poor improvement after the therapeutic course.
Conclusions: Our study revealed that MRI imaging is essential for assessing any SSNHL case. It can diagnose labyrinthine hemorrhage, whose course and prognosis differ significantly from idiopathic SSNHL.
Significance: Intratympanic prednisolone injection was effective in managing idiopathic SSNHL. On the other hand, this therapeutic modality was ineffective in improving SSNHL associated with labyrinthine hemorrhag
The meaning of the default language. A critical analysis of the development process of a WebGIS functionality.
No full textThe article aims at showing how softwares, and in this specific case GIS softwares, are imbued with
geographical imaginations, embodying cultural assumptions and biases of the people involved in
their developing. The author presents an analysis of the implementation of geographic metadata
internationalisation in GeoServer, a free software used to setup WebGIS. To perform the analysis
methodologies derived from Critical Code Studies are employed: by critically engaging with the
source code of the application it will be shown how it is loaded with geographical meanings that go
beyond the mere technical functioning of the software. The article thus aims, on one side, at
contributing to the field of critical code studies showing how a geographical approach might be
used to analyse source code. On the other side this essay aims at showing how GIS software should
be analysed also with respect to functionalities not directly related with spatial analysis and
geoprocessing, thus contributing to the field of critical GIS. The critical reading of source code, the
author will argue, can be an important tool for geographers that want to contribute to the
introduction of higher reflexivity inside open source software communities
Astrologia e alchimia nel Siglo de Oro: l'esempio di Quevedo
No full textRiassunto:
Nel presente elaborato si cerca di fornire al lettore una visione d’insieme, seppur non esaustiva, delle pseudo-scienze del secolo d’oro spagnolo. Astrologia e alchimia ricoprivano un ruolo fondamentale nell’antichità attraverso il popolo babilonese. Nel Siglo de Oro, invece, vengono spesso smentite da molti autori come Calderón de la Barca; mentre altri, quali Lope de Vega e Miguel de Cervantes, si trovano a metà fra la convinzione di accettarle e il piacere di accontentare il gusto del pubblico sbeffeggiando astrologi e alchimisti. La grande conoscenza in materia astrologica e alchemica e l’incredibile abilità verbale di Francisco de Quevedo porteranno alla luce la bellezza di ciò che governa il firmamento e le qualità della Terra, non perdonando chi si occupa di astrologia e alchimia solamente per trarne guadagno. Questo era un modo per denunciare i vizi della società dell’epoca. Sia in prosa che in lirica, l’autore spagnolo saprà conquistare il lettore con ingegnosi giochi di parole e acutezze.
Abstact:
In this research I woud like to present an overview of the pseudo-sciences of the Spanish golden age. Astrology and alchemy were a key in the interpretation of the Babylonian culture. On the other side, in the golden age of Spain, they are denied by authors like Calderón de la Barca. Others, like Lope de Vega and Miguel de Cervantes, are at a crossroad: they accept their good side but they also want to satisfy public’s taste, mocking astrologers and alchemists. In the same period, Francisco de Quevedo will demonstrate a great knowledge about astrology and alchemy. Troughout his incredible verbal ability he will present these pseudo-sciences in two different ways: the first one with a high tone by describing the beautiful celestial sky and his stars; the second one with a lower tone by teasing them. This is a way to criticise his society that was full of vices. The Spanish author will achieve the reader with puns and sharpness
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