7,414 research outputs found
Il mestiere di fare libri. Raffaele Crovi intellettuale e scrittore
No full textIl fascicolo monografico di «Humanitas», a cura di Giuseppe Lupo e Silvia Cavalli, è dedicato alla poliedrica figura di Raffaele Crovi. Gli interventi di Cesare De Michelis, Giuseppe Langella, Velania La Mendola, Alessandro Zaccuri, Pierluigi Castagnetti, Ferruccio Parazzoli, Raffaele Nigro e dello stesso Lupo, ripercorrono i vari aspetti della sua attività, dall'editoria al romanzo, dalla politica al versante biografico, restituendo la fisionomia di un protagonista emblematico del Novecento
O uso criativo dos paradoxos do direito: a aplicação dos princípios gerais do direito pela corte de Justiça europeia
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias JuridicasO trabalho pretende analisar o processo de aplicação dos princípios gerais do direito, especialmente no caso da prática jurisdicional da corte de justiça européia. Realiza-se uma análise teórica relativa aos princípios do direito, seguida de uma valoração empírica de sentenças consideradas paradigmáticas diante das teses até então desenvolvidas. A análise teórica procura descrever os princípios gerais como paradoxos constitutivos do sistema do direito. A partir de categorias trazidas da teoria da sociedade elaborada por Niklas Luhmanne Raffaele de Giorgi, aborda-se os conceitos de paradoxo, de auto-observação e de unidade, fechamento e abertura do sistema jurídico. Uma análise do funcionamento do ordenamento jurídico da comunidade européia permite que tais dados sejam observados, através de uma exame de algumas sentenças da corte européia de justiça
Raffaele Cavalluzzi, Tra etica e storia. La «Storia della colonna infame» di Alessandro Manzoni (Graphis, Bari 2009, 3^ ristampa)
No full text"Storia della colonna infame" di Alessandro Manzoni con un'ampia introduzione di Raffaele Cavalluzzi
Robotic services acceptance in smart environments with older adults: user satisfaction and acceptability study.
No full textIn Europe, the population of older people is increasing rapidly. Many older people prefer to remain in their homes but living alone could be a risk for their safety. In this context, robotics and other emerging technologies are increasingly proposed as potential solutions to this societal concern. However, one-third of all assistive technologies are abandoned within one year of use because the end users do not accept them. The aim of this study is to investigate the acceptance of the Robot-Era system, which provides robotic services to permit older people to remain in their homes. Six robotic services were tested by 35 older users. The experiments were conducted in three different environments: private home, condominium, and outdoor sites. The appearance questionnaire was developed to collect the users' first impressions about the Robot-Era system, whereas the acceptance was evaluated through a questionnaire developed ad hoc for Robot-Era. A total of 45 older users were recruited. The people were grouped in two samples of 35 participants, according to their availability. Participants had a positive impression of Robot-Era robots, as reflected by the mean score of 73.04 (SD 11.80) for DORO's (domestic robot) appearance, 76.85 (SD 12.01) for CORO (condominium robot), and 75.93 (SD 11.67) for ORO (outdoor robot). Men gave ORO's appearance an overall score higher than women (P=.02). Moreover, participants younger than 75 years understood more readily the functionalities of Robot-Era robots compared to older people (P=.007 for DORO, P=.001 for CORO, and P=.046 for ORO). For the ad hoc questionnaire, the mean overall score was higher than 80 out of 100 points for all Robot-Era services. Older persons with a high educational level gave Robot-Era services a higher score than those with a low level of education (shopping: P=.04; garbage: P=.047; reminding: P=.04; indoor walking support: P=.006; outdoor walking support: P=.03). A higher score was given by male older adults for shopping (P=.02), indoor walking support (P=.02), and outdoor walking support (P=.03). Based on the feedback given by the end users, the Robot-Era system has the potential to be developed as a socially acceptable and believable provider of robotic services to facilitate older people to live independently in their homes. [Abstract copyright: ©Filippo Cavallo, Raffaele Esposito, Raffaele Limosani, Alessandro Manzi, Roberta Bevilacqua, Elisa Felici, Alessandro Di Nuovo, Angelo Cangelosi, Fabrizia Lattanzio, Paolo Dario. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.09.2018.
Corrigendum to [The Assessment Tool for the Design of the Territories. The Impacts from the Road Infrastructure in the Inland Areas of the Province of Reggio Calabria] Procedia - Social and Behavioral Sciences Volume 223, 10 June 2016, Pages 534–541
No full textThe paper is the result of the joint work of the three authors. Scientific responsibility is attributable equally to Alessandro Rugolo, Francesco Calabrò, Raffaele Scriv
Raffaele Pettazzoni e la Storia delle religioni oltre il centenario
No full textRaffaele Pettazzoni e la Storia delle religioni oltre il centenari
Alessandro II e la nuova cattedrale
No full textIL contributo analizza il ruolo svolto da Alessandro II e dai canonici del Capitolo nella progettazione e realizzazione della nuova cattedrale, ricostruita tra il 1060 e il 1070, Vengono utilizzate fonti liturgiche e cronachistiche, note obituarie, epigrafi, i due "Sermones" sulla dedicazione della cattedrale e sulla traslazione dei corpi santi redatti quasi certamente dal vescovo Rangerio all'inizio del XII secolo e la descrizione degli altari della cattedrale trasmessa dal codice 124 della Biblioteca Capitolare. Il contributo evidenzia la prospettiva ecclesiologica che guidò la ricostruzione della cattedrale e la "imitatio Romae", ossia il richiamo al modello della Chiesa romana, tanto più significativo nel momento in cui Alessandro II, eletto papa, conservò anche le funzioni di vescovo di Lucca
Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy
No full textMobilized peripheral blood is increasingly used instead of bone marrow as a source of autologous hematopoietic stem/progenitor cells for ex vivo gene therapy. Here, we present an unplanned exploratory analysis evaluating the hematopoietic reconstitution kinetics, engraftment and clonality in 13 pediatric Wiskott-Aldrich syndrome patients treated with autologous lentiviral-vector transduced hematopoietic stem/progenitor cells derived from mobilized peripheral blood (n=7), bone marrow (n=5) or the combination of the two sources (n=1). 8 out of 13 gene therapy patients were enrolled in an open-label, non-randomized, phase 1/2 clinical study(NCT01515462) and the remaining 5 patients were treated under expanded access programs. Although mobilized peripheral blood- and bone marrow- hematopoietic stem/progenitor cells display similar capability of being gene-corrected, maintaining the engineered grafts up to 3 years after gene therapy, mobilized peripheral blood-gene therapy group shows faster neutrophil and platelet recovery, higher number of engrafted clones and increased gene correction in the myeloid lineage which correlate with higher amount of primitive and myeloid progenitors contained in hematopoietic stem/progenitor cells derived from mobilized peripheral blood. In vitro differentiation and transplantation studies in mice confirm that primitive hematopoietic stem/progenitor cells from both sources have comparable engraftment and multilineage differentiation potential. Altogether, our analyses reveal that the differential behavior after gene therapy of hematopoietic stem/progenitor cells derived from either bone marrow or mobilized peripheral blood is mainly due to the distinct cell composition rather than functional differences of the infused cell products, providing new frames of references for clinical interpretation of hematopoietic stem/progenitor cell transplantation outcome.
Data supporting the current study are part of a registered clinical trial (NCT01515462). These data are available under restricted access for the sensitive nature of the clinical data, access can be obtained by request to the corresponding author (Prof. Alessandro Aiuti, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, Milan, 20132 Italy.). We intend to reply to any requests within two weeks and we will share the deposited data only for research purposes. The non-clinical data generated in this study are also provided as the Source Data file associated to the published work
La lettera di Aristotele ad Alessandro
No full textAutenticità della lettera ad Alessandro di Aristotel
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