1,720,967 research outputs found
Giant atrial myxoma: an unexpected clinical presentation]. FT Mixoma atriale di grandi dimensioni: una inaspettata presentazione clinica
[Comprehensive cardiac computed tomography after acute myocardial infarction]. FT Valutazione mediante tomografia computerizzata cardiaca del postinfarto miocardico
Evaluation of Coronary Atherosclerosis by Multislice Computed Tomography in Patients With Acute Myocardial Infarction and Without Significant Coronary Artery Stenosis A Comparative Study With Quantitative Coronary Angiography
Background-It is known that 9% to 31% of women and 4% to 14% of men with acute myocardial infarction have normal coronary arteries or nonsignificant coronary disease at angiography. These patients represent a diagnostic and therapeutic challenge. Multislice computed tomography (CT) can noninvasively identify the presence of coronary plaques even in the absence of significant coronary artery stenosis. This study evaluated the role of 64-slice CT, in comparison with coronary angiography, in detecting and characterizing coronary atherosclerosis in patients with acute myocardial infarction without significant coronary artery stenosis.
Methods and Results-Thirty consecutive patients with acute myocardial infarction but without significant coronary stenosis at coronary angiography underwent 64-slice CT. All coronary segments were quantitatively analyzed by means of coronary angiography (CA-QCA) and 64-slice CT (CT-QCA). Forty-seven (10.4%) of the 450 coronary segments were not evaluable by CT. The mean proximal reference diameters at CT-QCA and CA-QCA were, respectively, 2.88 +/- 0.75 mm and 2.65 +/- 0.9 mm; the overall correlation between CT-QCA and CA-QCA for quantification of reference diameter was r(s)=0.77; P < 0.001. The mean percent stenosis was 14.4 +/- 8.0% at CT-QCA and 4.0 +/- 11.0% at CA-QCA and the correlation was r(s)=0.11; P=0.03. Overall CT-QCA showed the presence of 50 plaques, of which only 11 were detected by CA-QCA. CT-QCA identified 25 plaques in infarct-related coronary arteries. Positive remodeling was present in 38 of the 50 plaques (76%), with a higher prevalence in the coronary plaques not visualized by CA-QCA (82.1% versus 54.5%).
Conclusions-CT-QCA correlates well with CA-QCA in terms of coronary reference diameter analysis, but not stenosis quantification. Multislice CT can detect coronary atherosclerotic plaques in segments of nonstenotic coronary arteries that are underestimated by CA and may have an incremental diagnostic value for the diagnosis of acute myocardial infarction in patients without significant coronary stenosis at CA. (Circ Cardiovasc Imaging. 2008;1:205-211.)
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Use of 64-multislice computed tomography for detection of coronary thrombosis
Until now only few data have been published regarding the role of computed tomography for the detection of coronary thrombosis in coronary artery ectasias. We report the case of a 49-year-old man who was admitted to our hospital for prolonged chest pain followed by syncope. An early coronary angiography, performed after electrocardiography, the evaluation of cardiac enzymes and echocardiography, was carried out and revealed a diffuse coronary artery ectasia, involving particularly the right coronary artery. In addition, the following day the patient underwent contrast-enhanced cardiac 64-slice computed tomography, which revealed the presence of an intraluminal thrombus in the distal tract of the right coronary artery. Therefore, he was put on anticoagulant therapy and was discharged 2 days later. In conclusion, in this case, computed tomography played an additional and complementary role to coronary angiography. J Cardiovasc Med 9:1282-1284 (C) 2008 Italian Federation of Cardiology
Valore prognostico della tomografia computerizzata multistrato in una popolazione di pazienti con sospetta cardiopatia ischemica
Background: La tomografia computerizzata (TC) multistrato coronarica permette l’identificazione di placche coronariche con elevate accuratezza diagnostica ed è caratterizzata da un elevato potere predittivo negativo per l’esclusione di malattia coronarica se confrontata con l’angiografia coronarica. Tuttavia il potere predittivo della metodica non è ancora noto. Lo scopo di questo studio è di valutare il potere predittivo della TC multistrato coronarica per eventi cardiaci maggiori in paziente con sospetta cardiopatia ischemica.
Metodi: Sono stati sottoposti a TC 64 strati (Somatom Sensation 64, Siemens) 187 pazienti (119 uomini, età 62.5 ± 10.5 anni) con sospetta cardiopatia ischemica. I pazienti sono stati sottoposti a follow up ed è stata valutata l’incidenza di morte cardiaca, infarto miocardico non fatale e rivascolarizzazione miocardica.
Risultati: Su un totale di 2822 segmenti coronarici, 42 (1.5%) sono risultati non valutabili a causa di artefatti da movimento. La frequenza cardiaca media durante l’esame è stata pari a 62.5 ± 10.2 bpm. In 65 (34.7%) pazienti la TC multistrato ha mostrato l’assenza di aterosclerosi coronarica, in 87 (46.5%) pazienti la TC multistrato ha identificato placche coronarica non ostruttive (placche coronarica ≤50%), in 35 (18.8%) pazienti la TC multistrato ha identificato placche ostruttive (>50%). Dopo un follow up medio di 24 mesi, si sono verificati 23 eventi cardiaci maggiori. (3 infarti miocardici, 19 rivascolarizzazioni cardiache, 1 ospedalizzazione per angina instabile). Si è inoltre verificata una morte non cardiaca. Nei pazienti con coronarie normali, il tasso di eventi è stato pari a 0%. Tre dei pazienti con coronaropatia non ostruttiva sono stati sottoposti a rivascolarizzazione miocardica. Fra i pazienti con coronaropatia ostruttiva, 3 pazienti hanno avuto un infarto miocardico, 16 pazienti sono stati sottoposti a rivascolarizzazione e un paziente ha avuto una ospedalizzazione per angina instabile.
Conclusioni: La TC multistrato mostra un valore predittivo negativo pari al 100% per eventi cardiaci maggiori nei pazienti con arterie coronarie normali. L’incidenza di eventi cardiaci tende ad incrementare all’aumentare della severità della coronaropatia ed è maggiore nei pazienti con malattia coronarica ostruttiva
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Diagnostic accuracy of computed tomography coronary angiography in a high risk symptomatic population
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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