1,509 research outputs found
Fast Construction of Accurate Quaternion Splines
No full textIn 1992, Barr et al. proposed a method for interpolating orientations with unit quaternion curves by minimizing covariant acceleration. This paper presents a simple improved method which uses cubic basis functions to achieve a speedup of up to three orders of magnitude. A new criterion for automatic refinement based on the Euler-Lagrange error functional is also introduced. CR Categories: I.3.5 [Computer Graphics]: Computational Geometry and Object Modeling---Splines; G.1.6 [Numerical Analysis]: Optimization Keywords: Euler-Lagrange error functional, Quaternions, Splines, Optimization 1 Introduction In this paper, we discuss the interpolation of keyframe rotations with quaternion [6, 17] curves. Shoemake [16] introduced the idea of interpolating rotations with quaternions, but the constructed curves (slerps) did not satisfy an obviousvariational principle [21] as splines [2] do in flat space. Gabriel and Kajiya [4] then proposed a method that solved the (intrinsic) Euler-Lagrange e..
FIGURE 4 in A checklist of the New World species of Tillinae (Coleoptera: Cleridae), with an illustrated key to genera and new country records
No full textFIGURE 4. Distribution in the New World of: A. Tillinae Leach, B. Araeodontia Barr, C. Barrotillus Rifkind, D. Bogcia Barr, E. Bostrichoclerus Van Dyke, F. Callotillus Wolcott, G. Cymatodera Gray, H. Cymatoderella Barr, I. Lecontella Wolcott and Chapin, J. Monophylla Spinola, K. Onychotillus Chapin.Published as part of Burke, Alan F., Leavengood, John M. & Zolnerowich, Gregory, 2015, A checklist of the New World species of Tillinae (Coleoptera: Cleridae), with an illustrated key to genera and new country records, pp. 1-39 in Zootaxa 4059 (1) on page 7, DOI: 10.11646/zootaxa.4059.1.1, http://zenodo.org/record/23497
Cervical cancer with Human Papilloma Virus and Epstein Barr Virus positive
No full textThe Early-7 (E7) protein of HPV binds to the underphosphorelated form of the tumor suppressor
protein – pRb and displaces the E2F transcription factor that is normally bound by pRb. The latent
membrane protein-1 (LMP-1) of EBV prevents apoptosis of B cells by up regulating the expression
of bcl-2, and it activates growth promoting pathway that are normally triggered by T cell – derivate
signal. The aims of this study to know that in cervical cancer stay HPV and EBV.
DNA was isolated from nineteen sample cervical cancer tissues frozen section. Diagnose related
with HPV and EBV was made by Polymerase Chains Reaction (PCR).
The result of this experiment showed that from 19 samples diagnosed as cervical cancer, 17
samples are positive HPV and 13 samples had HPV and EBV positive. The conclusion of this
experiment is 89% of cervical cancers are infected with HPV and 68% also infected with HPV and
EBV
Neoeubria inbionis Shepard & Barr 2014, sp. n.
No full textNeoeubria inbionis sp. n. Figs. 1–4, 25–27 Type material. Holotype (male): COSTA RICA: Guanacaste Prov., Parque Nacional Rincón de la Vieja, Las Pailas Trail, 14-VI-2001, William D. Shepard, leg. // reared from pupa collected on wood in seep basin // HOLOTYPE Neoeubria inbionis Shepard & Barr [red label]. Deposited in INBC. Allotype (female): locality data same as holotype // ALLOTYPE Neoeubria inbionis Shepard & Barr [red label]. Deposited in INBC. Paratypes (2 M & 5 F): ECUADOR: Napo Prov., Huahua Sumaco, Km 44 on Hollin-Loreto Rd., XII-15-1989, Malaise Trap, MS/ JS Wasbauer, H. Real // CALIFORNIA STATE COLLN AGRICULTURE // PARATYPE Neoeubria inbionis Shepard & Barr [yellow label] (1 M) (EMEC); data same, except XII-16-1989 (1 F) (CSCA); data same, except XII-18-1989 (1 M) (CSCA); data same, except XII-19-1989 (1 F) (CSCA); data same, except XII-21-1989 (2 FF) (CSCA, EMEC); data same, except XII-22-1989 (1 F) (CSCA). Adult Description. Body oval; males (Fig. 3) smaller than females (Figs. 1–2, 4); males 4.6–5.0 mm long and 2.75 mm wide, females 5.0– 5.6 mm long and 2.8–3.5 mm wide. Integument color medium brown, shiny where setae sparse; covered dorsally with a combination of different kinds of setae: widely-spaced, long, erect blond and dark brown setae; sparse, shorter, pale brown setae; and very dense, recumbent, pale blond setae forming a pattern of broad bands and large spots. Venter uniformly clothed in medium-length pale blond setae. Aedeagus of trilobed type (Fig. 25) and lightly sclerotized. Basal piece long, reduced to ventral plate basally with lateral flanges that clasp the base of parameres. Parameres long, widest at apical three-fourths of aedeagus; tips narrow, curved laterally; dorsally conjoined just anterior to midlength. Penis lanceolate; shorter than parameres; tip slightly curved ventrally and laterally compressed; base deeply cleft. 1. Ectopria is omitted from the key because it is probable that the Neotropical species belong in other genera. Ovipositor (Fig. 26) with bacula long, 1.4 times as long as coxites, thin, gently curved; only partially sclerotized. Coxites 0.7 times as long as bacula; joined medially in basal half, divergent medially in apical half; laterally gently sinuate. Styli short, one-segmented. Long, thin accessory sclerite dorsally in basal third of membrane between coxites. Immature specimens examined. COSTA RICA: Alajuela, Alta Masis, 9 VI 2000, Río San Lorenzo [WDS- A-1302] // William D. Shepard, leg. (1 larva); Guanacaste Prov., Parque Nacional Rincón de la Vieja, Las Pailas Trail, 18-I-2000, William D. Shepard & Cheryl B. Barr, collected on wood in seep basin [WDS-A-1283](24 larvae, 1 pupa); data same, except 14-VI-2001, William D. Shepard, leg. [WDS-A-1386] (3 larvae, 3 pupae); data same, except 15-VI-2003, William D. Shepard & Cheryl B. Barr [WDS-A-1541] (11 larvae); data same, except Quebrada Pailas below Catarata, 14-VI-2001, William D. Shepard, leg. [WDS-A-1387] (1 larva). NICARAGUA: Río San Juan, Refugio Bartola, 10 VIII 2002, riffle 3, Río Bartola, William D. Shepard, leg. [WDS-A-1492] (1 larva). PANAMA: Chiriquí, Fortuna Forest Res., March 2004, Checo Colón-Gaud, leg. (1 larva). All immature specimens are deposited in EMEC. Etymology. Named in honor of INBio, the Instituto Nacional de Biodiversidad in Costa Rica. The case is genitive. Distribution. Nicaragua, Costa Rica, Panama and Ecuador, based on adult and larval specimens. Habitat. The type locality in Parque Nacional Rincón de la Vieja at an 780 m is a series of seeps in a small basin connected by a spring run to a narrow, slow-flowing forest stream which is a tributary of the Río Colorado. The entire area around the seeps and both streams is heavily forested and generally heavily shaded. In the seep basin the water is only about 2–3 cm deep over a substrate composed of a thick deposit of silt and fine detritus on which lie sticks and larger pieces of rotting, waterlogged wood (Fig. 27). In the basin the water is extremely slowmoving but in a couple of meters it begins to flow downhill in a narrow spring run which is crossed by the Las Pailas Trail between Stops 3 and 4. Larvae and pupae of N. inbionis were collected on pieces of decomposing wood found in the seep basin. Larvae were positioned below the water’s surface and pupae were above. The water is likely hypoxic because of the fine organic detritus substrate, coupled with the lack of sunlight for aquatic photosynthesizers due to the heavily-shaded nature of the site. Possession of a plastron facilitates larval survival in this water. Neoeubria was the only psephenid present in the seep area, and the only other co-occurring aquatic byrrhoid Coleoptera was an unidentified ptilodactylid larva. Other arthropods present in the seep area included aquatic Hemiptera, Belostoma (Belostomatidae) and Ambrysus (Naucoridae), and the crustacean Hyallela (Amphipoda). No specimens were collected from the spring run formed by the seeps. A single larva was collected in a second, larger stream, Quebrada Pailas, a tributary of the Río Colorado, which is also located along the Las Pailas Trail. The other sites at which larvae were collected by the senior author are also forest streams, although with rocky substrates and faster flow. Although the particular microhabitat of the larvae at these sites is unknown, at all of them submerged wood was common. Neoeubria inbionis has been collected at elevations ranging from as low as 40+ m in Nicaragua, to as high as 780 m in Costa Rica. The Ecuadorian adults were all taken in Malaise traps which were set in a forested area to catch flies. Although we could obtain no further information beyond the label data, collection of adults via Malaise traps indicates that N. inbionis adults behave like other eubriine adults and fly near the aquatic habitat in which the larvae occur. Phylogeny. In the recent phylogeny of the Psephenidae by Lee et al. (2007), Neoeubria is included as “Genus A.” In the most parsimonious tree Neoeubria is placed in a basal trichotomy within the subfamily Eubriinae. The trichotomy positions Neoeubria in one branch, Sclerocyphon + Tychepsephus in another branch, and the remainder of the eubriine genera in a third branch.Published as part of Shepard, William D. & Barr, Cheryl B., 2014, Neoeubria inbionis Shepard & Barr, a new genus and new species of Neotropical water penny beetle (Coleoptera: Psephenidae: Eubriinae), with a key to the adult Eubriinae of the Neotropic Zone, pp. 553-568 in Zootaxa 3811 (4) on pages 564-567, DOI: 10.11646/zootaxa.3811.4.7, http://zenodo.org/record/491902
Conditional immortalization of human B cells by CD40 ligation
No full textIt is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro. Here we readdress this issue, studying the long-term proliferation potential of human B cells. It was shown earlier that human B cells from peripheral blood of healthy donors can be efficiently induced to proliferate for up to ten weeks in vitro by stimulating their receptor CD40 in the presence of interleukin-4. When we applied the same stimuli under conditions of modified cell number and culture size, we were surprised to find that our treatment induced B cells to proliferate throughout an observation period of presently up to 1650 days, representing more than 370 population doublings, which suggested that these B cells were immortalized in vitro. Long-term CD40-stimulated B cell cultures could be established from most healthy adult human donors. These B cells had a constant phenotype, were free from Epstein-Barr virus, and remained dependent on CD40 ligation. They had constitutive telomerase activity and stabilized telomere length. Moreover, they were susceptible to activation by Toll-like receptor 9 ligands, and could be used to expand antigen-specific cytotoxic T cells in vitro. Our results indicate that human somatic cells can evade senescence and be conditionally immortalized by external stimulation only, without a requirement for genetic manipulation or oncoviral infection. Conditionally immortalized human B cells are a new tool for immunotherapy and studies of B cell oncogenesis, activation, and function
Of triggers, supersymmetry and photons: triggers for dark matter and a search for gauge-mediated supersymmetry breaking with the ATLAS detector at the LHC
No full textThis thesis summarises research using the ATLAS experiment to search for Dark Matter. A performance study of the ATLAS Run 2 trigger is presented, introducing relevant performance metrics and the algorithms that have lead to the successful operation of the trigger during LHC Run 2. The \texttt{trktc} algorithm, a candidate algorithm for the Run 3 trigger, and its performance are discussed in detail, motivating the combination of a tracking-based algorithm with a Run 2 algorithm in constructing the Run 3 primary trigger. A search for new physics in +invisible in of data collected at with the ATLAS experiment is presented. Searches are performed for events in which one Higgs boson decays to and the other to . The final state of was previously unexplored by the ATLAS experiment. No evidence for physics beyond the Standard Model has been found. Results are interpreted in the context of Gauge-Mediated Supersymmetry Breaking models. Limits are presented assuming a pure Higgsino neutralino, which decays via or . Assuming , models with are excluded. For lower branching fractions of , models with neutralino masses of up to are excluded. Models with are excluded for branching fractions as low as . The presented search almost completely closes a gap in the ATLAS experiment's sensitivity to Dark Matter models
. 84 (2013) enero-abril. Historias. Revista de la Dirección de Estudios Históricos
No full text- 1968, un año inolvidable por Eric Hobsbawm. - Una carta de Alfred H. Barr Jr. al editor de College Art Journal porAlfred H. Barr Jr. - Una encuesta sobre las artes lejanas ¿Se las admitirá en el Louvre? por Félix Fénéon. - Fray Francisco Ximénez y el Popol Vuh por Rodrigo Martínez Baracs. - La experiencia del orden en las fiestas de Independencia porfirianas de la ciudad de México (1887-1900) por José Rodrigo Moreno. - La novela folletinesca y Manuel Payno por José Joaquín Blanco. - Leer la ausencia: las ciudades de Indias y las Cortes de Castilla, elementos para su estudio (siglos XVI y XVII) por Óscar Mazín. - Manifestaciones culturales en las crónicas de los soldados de la conquista de Nueva España por Guillermo Turner R. - La noche de Carlota por Salvador Rueda Smithers. - La empresa eléctrica por Carlos Marichal. - Retratos de pasión por Rebeca Monroy Nasr. - De la mina empresa a la región por Alma Parra. - Crestomanía por José Mariano Leyva
Oriented Tensor Reconstruction Portions reprinted, with permission, from Zhukov and Barr [26]. Copyright © 2002, IEEE.
No full textAcknowledgements
No full textiii I would like to thank my advisors, Alan H. Barr and Peter Schröder, and all people of th
Figure 21 from: Burke A, Zolnerowich G (2017) Taxonomic revision of the New World Tillinae Leach sensu lato (Coleoptera: Cleridae). ZooKeys 719: 75-157. https://doi.org/10.3897/zookeys.179.21253
No full textFigure 21 -
Distribution in the New World of: A Tillinae Leach B Araeodontia Barr C Barrotillus Rifkind D Bogcia Barr E Bostrichoclerus Van Dyke F Callotillus Wolcott G Cymatodera Gray (not treated here) H Cymatoderella Barr I Lecontella Wolcott & Chapin J Monophylla Spinola K Onychotillus Chapin L Neocallotillus Burke
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