27 research outputs found
Особливості нейрональної активності фронтальної кори щурів при пентиленететразоловому кіндлінзі = The peculiarities of rats frontal cortex neuronal activity during pentylenetetrazol kindling
No full textDenisenko О В, Shandra Al Al, Vastyanov R S. Особливості нейрональної активності фронтальної кори щурів при пентиленететразоловому кіндлінзі = The peculiarities of rats frontal cortex neuronal activity during pentylenetetrazol kindling. Journal of Education, Health and Sport. 2015;5(5):342-354. ISSN 2391-8306. DOI 10.5281/zenodo.17879
http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%285%29%3A342-354
https://pbn.nauka.gov.pl/works/561485
http://dx.doi.org/10.5281/zenodo.17879
Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive
Deklaracja.
Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.
Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.
The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).
© The Author (s) 2015;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 15.02.2015. Revised 27.04.2015. Accepted: 20.05.2015.
УДК 612.825.1
ОСОБЛИВОСТІ НЕЙРОНАЛЬНОЇ АКТИВНОСТІ ФРОНТАЛЬНОЇ КОРИ ЩУРІВ ПРИ ПЕНТИЛЕНЕТЕТРАЗОЛОВОМУ КІНДЛІНЗІ
THE PECULIARITIES OF RATS FRONTAL CORTEX NEURONAL ACTIVITY DURING PENTYLENETETRAZOL KINDLING
1,2О. В. Денисенко, 1Ол. Ол. Шандра, 1Р. С. Вастьянов
1,2О В Denisenko, 1Al Al Shandra, 1R S Vastyanov
1Одеський національний медичний університет, Одеса;
2Одеський національний університет ім. І. І. Мечникова, Одеса
1Odessa National Medical University, Odessa;
2 Odessa I. I. Mechnikov National University, Odessa
Summary. The article deals with the characteristics of interictal neuronal activity changes in frontal cortex different layers of rats during the pentylenetetrazol kindling development. Two types of EEG activity were shown to be presented in these conditions. The 1st type of neuronal activity characterized by motor cortex II/III layers neuronal activity hyperactivation. The 2nd type neuronal activity characterized by the motor cortex deep (IV-VI) layers neurons hyperactivation. The authors conclude that the registered neuronal activity differences in the conditions of the chronic seizures experimental model mark the functional relationship between the epileptic and antiepileptic brain systems. They are also the basis for cortical networks formation and activation peculiarities further investigation in conditions of neurons excessive activation development during the prolonged convulsive influences.
Key words: kindling, pentylenetetrazol, frontal cortex, interictal intracellular activity, proconvulsive and anticonvulsive mechanisms.
ОСОБЕННОСТИ НЕЙРОНАЛЬНОЙ АКТИВНОСТИ ФРОНТАЛЬНОЙ КОРЫ КРЫС ПРИ ПЕНТИЛЕНЕТЕТРАЗОЛОВОМ КИНДЛИНГЕ. В работе исследовали особенности изменений интериктальной нейрональной активности в различных слоях фронтальной коры мозга крыс при формировании пентиленететразолового киндлинга. Показано, что в этих условиях у крыс формируются два типа ЭЭГ-активности. Первый тип нейрональной активности характеризуется гиперактивацией активности нейронов II/III слоев моторной коры. Второй тип нейрональной активности характеризуется гиперактивацией нейронов глубинных (IV-VI) слоев коры мозга. Авторы уверены, что зарегистрированные разновидности нейрональной активности в условиях развития экспериментальной модели хронической судорожной активности знаменуют функциональные взаимоотношения между активностью эпилептической и антиэпилептической систем мозга и являются основанием для дальнейшего выяснения особенностей формирования и активации кортикальных сетей при развитии чрезмерной активации нейронов при действии длительных просудорожных воздействий.
Ключевые слова: киндлинг, пентиленететразол, фронтальная кора, интериктальная внутриклеточная активность, просудорожные и противосудорожные механизмы.
Резюме. В роботі досліджували особливості змін інтеріктальної нейрональної активності у різних шарах фронтальної кори мозку щурів при формуванні пентиленететразолового кіндлінгу. Показано, що за цих умов у щурів відзначається формування двох типів ЕЕГ-активності. Перший тип нейрональної активності характеризується гіперактивацією активності нейронів II/III шару моторної кори. Другий тип нейрональної активності характеризується гіперактивацією нейронів глибинних (ІV-VI) шарів кори мозку. Автори впевнені, що зареєстровані різновиди нейрональної активності протягом розвитку експериментальної моделі хронічної судомної активності висвітлюють функціональні взаємовідносини між активністю епілептичної та антиепілептичної систем мозку та є підставою для подальшого з’ясування особливостей формування та активації кортикальних мереж при розвитку надмірної активації нейронів за умов дії тривалих просудомних впливів.
Ключові слова: кіндлінг, пентиленететразол, фронтальна кора, інтеріктальна внутрішньоклітинна активність, просудомні та протисудомні механізми
Proximity to Industrial Releases of Toxins and Childhood Respiratory, Developmental, and Neurological Diseases: Environmental Ascription in East Baton Rouge Parish
No full textRecent research by Legot et al. (2010a, 2010b) has identified East Baton Rouge Parish (EBR) as a locus of particularly high volumes of emissions of developmental neurotoxins, i.e., those toxins that put children’s health and, especially, learning abilities at greatest risk. Many developmental neurotoxins are also classified as respiratory toxins, which are also linked to the sorts of childhood diseases (e.g., asthma) that impact school performance. This case study specifies the degree to which proximity to the main sources of these toxins in EBR is associated with high rates of neurodevelopmental diseases and childhood asthma. We also examine the relationship between proximity to toxins and race and class.<span> </span>We find very strong patterns: disease rates are significantly higher in zip codes close to pollution “hot spots” than in more distant zip codes, as are percent minority and percent poverty.<span> </span>This is evidence of “environmental ascription”, the existence of multiple, overlapping ascriptions based on race, class, and “place”.<span> </span>Vulnerable populations are disproportionately exposed to the sorts of toxins that limit their life chances.<p></p>environmental ascription; developmental neurotoxins; respiratory toxins; childhood diseases; vulnerable populations
Posttraumatic Stress Disorder and Consensual, Unwanted Sex: The Role of Frequency, Gender, and Reasons for Consenting
No full textConsensual unwanted sex (CUS), which occurs when an individual agrees to sexual activity they do not want, remains a common but understudied experience across different ages, genders, and sexual orientations (Nickull et al., 2025; Rubinsky, 2020). Most existing research on CUS focuses on younger women in college (Peterson, 2024), often in dating or casual sexual relationships (Courtice et al., 2021), leaving a significant gap in understanding CUS among adults of varying ages, genders, and relationship lengths. Some studies link CUS to both positive and negative outcomes in relationship quality and sexual satisfaction (Froemming, 2020; Himanen & Gunst, 2024). Participants have also reported posttraumatic stress symptoms (PTSS), including self-blame, hypervigilance, avoidance, and negative changes in mood and thinking (Kern & Peterson, 2021). However, existing studies rarely assess posttraumatic stress disorder (PTSD) in relation to CUS. This dissertation uses the PTSD Checklist (PCL-5; Weathers et al., 2013) according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, Text Revision (DSM-5-TR, American Psychiatric Association [APA], 2022) to assess PTSD diagnoses (dx), the severity of each PTSS, and experiences of unrecognized coercion among adults aged 21 and older who report CUS in romantic relationships lasting at least two months. The study compares these outcomes by gender, CUS frequency, and reasons for consent.Counselin
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Who We Are Is How We Win: Ethnic-Racial Identity as a Universal Developmental Asset for the Culture, the Credits, & College Student Success
No full textCompleting college is an educational milestone that has meaningful longer-term implications for students in the U.S. (e.g., economic mobility) and their children (Chetty et al., 2017; Reeves & Krause, 2018). Despite the prevalence of ethnoracially minoritized students in the K-12 and overall U.S. populations, Black and Latine students complete college at lower rates than their peers (Department of Education, 2020; U.S. Census, 2020), thus making economic opportunity harder to attain. College completion and healthy progression into adulthood require similar developmental tasks, e.g., defining one’s career, academic goals, and personal identities (Carnevale et al., 2010, 2013; Chickering & Reisser, 1997; Magolda, 2007). Thus, it is possible that a richer, more complex understanding of personal identity development as it relates to college success, career development, and race/ethnicity (i.e., ethnic-racial identity; Umaña-Taylor et al., 2014) would help close college success gaps. Ethnic-racial identity processes are linked with myriad positive developmental outcomes (e.g., Umaña-Taylor, 2023) and have been leveraged, along with concepts such as campus racial climate (e.g., Hurtado & Carter, 1997; Paris & Alim, 2014), to ground various K-12 reform efforts, collegiate cultural/affinity supports, and culturally relevant/sustaining educator programs. However, less work has explored systematically incorporating ethnic-racial identity, with its multi-dimensional, psychological construction, into models or the practice of college student success. I address this gap in my dissertation by first reviewing leading models for young adult development and college success and presenting a new model of postsecondary success that incorporates ethnic-racial identity. Then, I explored preliminary evidence of the model’s theoretical notions using a nationwide survey of 755 U.S. undergraduate college students—a convenience sample recruited online from multiple U.S. regions. Finally, I assessed the feasibility of bringing an ethnic-racial identity curriculum (i.e., The Identity Project) to college campuses using qualitative interview and survey data gathered during a campus-based pilot study with 48 undergraduate students enrolled at one private college. In doing so, I illuminate possible ways for colleges to leverage student ethnic-racial identity—the fuller, contextualized psychological understanding of race/ethnicity—as an asset on campus and, in turn, increase the probability of all college students attaining educational success and economic opportunity.Educatio
Monitor de configuraciones Mikrotik
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on de las con guraciones de dispositivos Mikrotik con las versiones de RouterOS 5 y 6
como los problemas encontrados durante el proyecto y las soluciones aplicadas. El sistema es una
aplicaci on web que est a implementada mediante una variaci on de la pila de tecnolog as MEAN
(MongoDB, ExpressJS, AngularJS y NodeJS), en la que el sistema de la base de datos no es
MongoDB sino NeDB, una variante de la anterior que se almacena en cheros locales. Los dos
principales objetivos de la aplicaci on son alertar a los usuarios de esta de los cambios producidos
en las con guraciones de los dispositivos Mikrotik registrados en la aplicaci on y mantener un
hist orico de las con guraciones. Al nal del documento, se cuentan las conclusiones personales
del estudiante del desarrollo del sistema y la estancia en pr acticas en la empresa
PENERAPAN DIGITALISASI DI PESANTREN AL ADZKAR DENGAN MENGGUNAKAN POWER POINT SEBAGAI BENTUK PEMBELAJARAN YANG MODERN
No full textMicrosoft Power Point merupakan salah satu aplikasi media presentasi digunakan sebagai metode pembelajaran yang modern. Di zaman serba digital saat ini metode pembelajan menggunakan power point sangat dibutuhkan di instusi pendidikan terutama di pesantren. Di pesantren memprioritaskan ilmu agama sehingga dalam pembelajarannya sangat jarang menggunakan power point, lebih sering menggunakan media buku atau kitab. Hal ini juga terjadi di pesantren Al Adzkar hasil dari diskusi terhadap pimpinan dan staf pesantren. Maka dari itu pengabdian kepada masyarakat mahasiswa universitas pamulang merasa perlu adanya digitalisasi dengan mengguanakan power point sebagai bentuk pembelajaran yang modern. Sehingga diharapkan pesantren Al Adzkar dapat menerapkannya kepada para santri maupun guru untuk membangun relasi pembelajaran yang modern dengan aktif dan kreatif
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The peculiarities of rats frontal cortex neuronal activity during pentylenetetrazol kindling
No full textВ роботі досліджували особливості змін інтеріктальної нейрональної активності у різних шарах фронтальної кори мозку щурів при формуванні пентиленететразолового кіндлінгу. Показано, що за цих умов у щурів відзначається формування двох типів ЕЕГ-активності. Перший тип нейрональної активності характеризується гіперактивацією активності нейронів II/III шару моторної кори. Другий тип нейрональної активності характеризується гіперактивацією нейронів глибинних (ІV–VI) шарів кори мозку. Автори впевнені, що зареєстровані різновиди нейрональної активності протягом розвитку експериментальної моделі хронічної судомної активності висвітлюють функціональні взаємовідносини між активністю
епілептичної та антиепілептичної систем мозку та є підставою для подальшого з’ясування особливостей формування та активації кортикальних мереж при розвитку надмірної активації нейронів за умов дії тривалих просудомних впливів.The article deals with the characteristics of interictal neuronal activity changes in frontal cortex different layers of rats during the pentylenetetrazol kindling development. Two types of EEG activity were shown to be presented in these conditions. The 1st type of neuronal activity characterized by motor cortex II/III layers neuronal activity hyperactivation. The 2nd type neuronal activity characterized by the motor cortex deep (IV–VI) layers neurons hyperactivation. The authors conclude that the registered neuronal activity differences in the conditions of the chronic seizures experimental model mark the functional relationship between the epileptic and antiepileptic brain systems. They are also the basis for cortical networks formation and activation peculiarities further investigation in conditions of neurons excessive activation development during the prolonged convulsive influences.В работе исследовали особенности изменений интериктальной нейрональной активности в различных слоях фронтальной коры мозга крыс при формировании пентиленететразолового киндлинга. Показано, что в этих условиях у крыс формируются два типа ЭЭГ-активности. Первый тип нейрональной активности характеризуется гиперактивацией активности нейронов II/III слоев моторной коры. Второй тип нейрональной активности характеризуется гиперактивацией нейронов глубинных (IV–VI) слоев коры мозга. Авторы уверены, что зарегистрированные разновидности нейрональной активности в условиях развития экспериментальной модели хронической судорожной активности знаменуют функциональные взаимоотношения между
активностью эпилептической и антиэпилептической систем мозга и являются основанием для дальнейшего выяснения особенностей формирования и активации кортикальных сетей при развитии чрезмерной активации нейронов при действии длительных просудорожных воздействий
Understanding Appalachian Microaggression from the Perspective of Community College Students in Southern West Virginia
No full textThe term Appalachian is wrongly understood to represent a single culture of rural White poverty (Keefe, 2005). This conception contains stereotypical images that obscure hardships many rural White Central Appalachians face. Similar to other oppressed minorities in the U.S., what it means to be Appalachian is a social construction based on what differs them from the White hegemony. Recent scholarship on discrimination recognizes the importance of microaggression, small insults and slights experienced frequently by people from minority groups (Sue, et. al., 2007). Microaggression may be an especially insidious mechanism in the oppression of Appalachian people, since the derogatory stereotypes are broadly accepted while their oppressed status tends to not be acknowledged. This study applied qualitative focus group methodology to understand perceptions of microaggression and oppression among a sample of college students living in rural Central Appalachia. Results reveal themes of microaggression. Identifying Appalachian microaggression provides evidence of marginalized status and offers a framework for understanding how the social construction of White Appalachian perpetuates reduced status, stereotypes, and prejudice. Implications are discussed to consider how to foster resilience to oppression among rural White Central Appalachian people
Migration, Openness and the Global Preconditions of 'Smart Development'
No full textIn this article, we present a first empirical reflection on 'smart development', its measurement, possible 'drivers' and 'bottlenecks'. We first provide cross-national data on how much ecological footprint is used in the nations of the world system to 'deliver' a given amount of democracy, economic growth, gender equality, human development, research and development, and social cohesion. To this end, we first developed UNDP-type performance indicators on these six main dimensions of development and on their combined performance. We then show the non-linear regression trade-offs between ecological footprints per capita on these six dimensions of development and their combined performance index. The residuals from these regressions are our new measures of smart development: a country experiences smart development, if it achieves a maximum of development with a minimum of ecological footprint. We then look at the cross-national drivers and bottlenecks of this 'smart development' and compare their predictive power using stepwise regression procedures. Apart from important variables and indicators, derived from sociological dependency and world systems theories, we also test the predictive power of several other predictors as well. Our estimates underline the enormous importance of the transfer of resources from the center to the periphery, brought about by migration, with huge statistical observed positive effects of received worker remittances on smart human development, Happy Life Years, smart gender justice, smart R&D, and both formulations of the smart development index.index numbers and aggregation, environment and development, environment and trade, smart development, sustainability, environmental accounts and accounting, environmental equity, population growth, international migration, remittances
