326,000 research outputs found

    The role of antioxidant activity in the prevention and treatment of infertility caused by cisplatin in rats

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    Kurt, Nezahat/0000-0002-1685-5332; AKSOY, Ayse Nur/0000-0002-3793-9797; AKSOY, Mehmet/0000-0003-0867-8660Background/Aims:To investigate the importance of antioxidant activity in infertility caused by cisplatin in rats. Methods: Rats in cisplatin control (CG), Vitamin E+cisplatin (ECG), Vitamin C + cisplatin (CCG), Hippophae rhamnoides extract (HRE) + cisplatin (HRECG), and thiamine pyrophosphate (TPP) + cisplatin (TPPCG) groups were injected intraperitoneally (ip) with (100 mg/kg) Vitamin E, Vitamin C, HRE, and TPP, respectively. One hour later, ip cisplatin was administered (5 mg/kg), and then antioxidant medications were continued for 10 days. Cisplatin + Vitamin E (CEG-1), cisplatin + Vitamin C (CCG-1), cisplatin + HRE (CHREG-1), and cisplatin + TPP (TPPCG-1) rats received cisplatin (5 mg/kg, ip) and were kept for 10 days. At the end of that period, rats received antioxidant medications for 10 days. (n = 12, for each group). Six rats from each group were sacrificed. Ovaries were removed to measure malondialdehyde, total glutathione, glutathione S-transferase, and glutathione reductase levels. the remaining rats were kept in a suitable laboratory environment. Results: Cisplatin-induced oxidative stress was best prevented by HRE, Vitamin E, Vitamin C, and TPP, in that order. However, infertility caused by cisplatin was only prevented and treated by TPP. Conclusion: Oxidative stress is not a major component in the pathogenesis of cisplatin-associated infertility. (C) 2015 S. Karger AG, Base

    CYTOGENETIC EFFECTS OF ELECTROMAGNETIC FIELDS FROM TELEVISION ON ALLIUM CEPA L. ROOT TIP CELLS

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    Allium cepa bulbs were exposed for eight hours a day for three days at electromagnetic fields from television. Five bulbs were set up for each group (0.25 m, 0.50 m, 1 m and 2 m distances from television). Mitotic index, phase frequencies and chromosome aberrations were evaluated in exposed groups as compared with control group. Data obtained showed that electromagnetic fields from television significantly increased the mitotic index at close distances. However, there were no significantly differences in the phase frequencies and chromosome aberrations frequencies

    Investigation of Wolbachia spp. and Spiroplasma spp. in Phlebotomus species by molecular methods

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    The aim of this study was to determine the presence of Wolbachia spp. and Spiroplasma spp. in natural populations of sand flies in Turkey by molecular methods. A total of 40 Phlebotomus specimens (19 female and 21 male) were used in this study. Genomic DNA from whole sand flies was isolated and Wolbachia spp. infection prevalence was investigated by using Wolbachia gene specific primer sets (wsp and GroEL). In addition, the DNA were analyzed for the presence of Spiroplasma infections utilizing bacterium specific 16 S rDNA PCR-amplification primers. Results of this analysis showed a Wolbachia infection prevalence of 70% (28/40). There was no sex-bias in infection prevalence, being 76% (16/21) and 63% (12/19) in males and females, respectively. Analysis of Spiroplasma infections indicated that 26% (5/19) of female sand flies were positive for infection, while none of the screened males (0/21) were positive. Of the 40 sand fly samples, only 2 were found to be positive for both Wolbachia spp. and Spiroplasma spp. The present study demonstrates the presence of Wolbachia and Spiroplasma infections in the natural sand fly populations in Turkey. This is the first report on Spiroplasma infection in the sand flies from Turkey. © 2018 The Author(s).This study was supported by TUBITAK (The Scientific and Technical Research Council of Turkey) (TUBITAK, BIDEB-2219). We are grateful to all the members of the Aksoy Lab for their contributions to the project especially Dr. Geoffrey M. Attardo for preparing tubulin primers and comments on the manuscript, Maria Gorreti Onyango, Michelle O’Neill and Yineng Yang for helping in Molecular Systematics Laboratory. We also thank Prof. Dr. Yusuf ÖZBEL for providing Phlebotomus samples that were collected for a previous TUBİTAK project (project number:112T270). We thank Mehmet Karakus from Aksoy laboratory for his critical reading of the paper. This study was presented at the XX. National Congress of Parasitology (25-29 September 2017, Eskişehir-Turkey)

    Diffusive author(s), cohesive author: Analysis of S/N (1994)

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    This study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Why figs? An old taste and a new perspective

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    1st International Symposium on Fig -- JUN 24-28, 1997 -- IZMIR, TURKEYInt Soc Hort Sc

    Genotoxic Effects of Electromagnetic Fields from High Voltage Power Lines on Some Plants

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    Allium cepa bulbs were germinated in pots for three days on treatment area on which 380 kV high voltage power lines are passing. Ten bulbs were set up for each treatment area (0 m (meter), 10 m, 25 m, 50 m and 100+ m for control from power lines). Triticum baeoticum Boiss. subsp. baeoticum seeds were collected at same distance from power lines on planted field. Ten seeds from each area were germinated in Petri dishes for three days in laboratory. The treatment groups were compared with the control group for mitotic index and chromosome aberrations. Data obtained showed that electromagnetic fields from high voltage power lines increased the mitotic index and chromosome aberrations

    The Investigation of the Digital Literacy Levels of Classroom Teachers

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    Dünyada olduğu gibi ülkemizde de hız kesmeden gelişen teknoloji çalışmaları eğitimde de kendini göstermektedir. COVİD19 pandemi nedeniyle eğitimin ulusal çapta zorunlu olarak uzaktan yapılmasıyla eğitimde teknoloji kullanımı zorunlu hale gelmiştir. Bu süreç dijital yerli olarak adlandırılan günümüz öğrencilerine sürece uyum sağlamasının kendini geliştiren ve teknolojiyi derslerde kullanabilen öğretmenler ile mümkün olduğunu göstermiştir. Bu durumda öğretmenlerin dijital okuryazarlık becerileri uzaktan eğitimin verimliliği açısından önemlidir. Bu çalışmada, sınıf öğretmenlerinin dijital okuryazarlık becerilerinin çeşitli değişkenlere bağlı olarak incelenmesi amaçlanmıştır. Bu çalışma nicel araştırma yöntemlerinden tarama modeli kullanılarak gerçekleştirilmiştir. Çalışmaya Türkiye’nin yedi bölgesinden toplamda 41 ilde görev yapan 329 sınıf öğretmeni gönüllü olarak katılmıştır. Çalışmada veri toplama aracı olarak “Kişisel Bilgi Formu” ve “Dijital Okuryazarlık Ölçeği” kullanılmıştır. Araştırmadan elde edilen bulgulara göre araştırmanın birinci alt problemine ilişkin bulgularda sınıf öğretmenlerinin kendilerini yüksek düzeyde dijital okuryazar gördükleri sonucuna ulaşılmıştır. Cinsiyet değişkenine göre dijital okuryazarlık düzeylerine bakıldığında kadın ve erkek öğretmenlerin benzer düzeyde dijital okuryazar oldukları sonucuna ulaşılmıştır. Sınıf öğretmenlerinde yaş arttıkça dijital okuryazarlık düzeyinin azaldığı görülmüştür. Ayrıca lisans üstü eğitime sahip öğretmenlerin dijital okuryazarlık düzeyleri diğer öğrenim düzeyindeki öğretmenlere kıyasla daha yüksek bulunurken, 21-25 yıl kıdeme sahip öğretmenlerin dijital okuryazarlık düzeyleri diğer kıdemdeki, öğretmenlere göre daha düşük bulunmuştur. Öğretmenlerin günlük internet kullanım ve günlük dijital araçları kullanım sürelerine bakıldığında anlamlı bir farklılaşma görülmemiştir.Technology studies that develop in our country without slowing down, as in the world, also show itself in education. Due to the COVID-19 pandemic, the use of technology in education has become mandatory with the compulsory distance education at national level. This process has shown us that today's students, who are called digital natives, can adapt to the process with teachers who develop themselves and can use technology in lessons. In this case, digital literacy skills of teachers are important for the efficiency of education. In this study, it is aimed to examine the digital literacy skills of classroom teachers depending on various variables. This study was created using the survey model, one of the quantitative research methods. The study of Turkey's 41 provinces who served a total of 329 classroom teachers from seven regions participated voluntarily. "Personal Information Form" and "Digital Literacy Scale" were used as data collection tools. According to the findings obtained from the study, it was concluded that classroom teachers perceived themselves as digitally literate in the findings related to the first sub-problem of the study. Considering the digital literacy levels of the gender variable, it was concluded that male and female teachers were digitally literate at a similar level. It has been observed that as the age of the classroom teachers increases, the level of digital literacy decreases. In addition, digital literacy levels of teachers with postgraduate education were found to be higher than teachers of other education levels, while the digital literacy levels of teachers with a seniority of 21-25 years were found to be lower than those of other senior teachers. When we look at teachers' daily internet usage and daily digital tools usage, no significant differentiation was observed
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