4,108 research outputs found
Anugerah bakar semangat Abdul Rais
Get PDFKuala Lumpur: "Alhamdulillah,ini bukti kerajaan mengiktiraf sumbangan golongan seperti saya," kata penerima Anugerah Tokoh Pekerja Negara kategori Orang Kelainan Upaya (OKU) Abdul Rais Mohamad Mokhtar, 50, pada Majlis Perhimpunan Hari Pekerja 2013, semalam.Pegawai Penyelidik Sosial di Universiti Utara Malaysia (UUM) Sintok, Kedah, itu tidak menyangka akan merangkul anugerah itu yang disampaikan Perdana Menteri Datuk Seri Najib Razak
Surface immunoglobulins as a target for antibody therapy
No full textThis thesis relates to the therapeutic use of antibody in the treatment of chronic lymphocytic leukaemia. The antibody was raised in sheep and directed against idiotypic determinants (Id) on the surface immunoglobulins of the neoplastic lymphocytes. Three patients received the therapy. The author's contributions to this work were to characterise Fab fragments prepared from the surface immunoglobulin, to investigate the catabolism of infused xenogeneic antibody, and to assist in the clinical trials.The work is divided into three sections. The first section deals with the proteolytic cleavage of surface and secreted immunoglobulins, the second with the catabolic rates of immunoglobulins in xenogeneic animals, the third with the clinical trials. In the first section, papain was used to cleave surface immunoglobulins on the neoplastic lymphocytes from chronic lymphocytic leukaemia patients. The immunoglobulins were cleaved in situ, releasing Fab fragments that carry idiotypic determinants specific to the particular neoplastic clone of cells. Sheep were immunised with the Fabµ fragments to produce anti-Id antibodies. The cleavage of surface IgM with papain released Fabµ fragments and another molecule which we termed fragment X. Fragment X contains Fabµ determinants which are not present on Fabµ prepared from serum IgM. These non-Fabµ determinants were highly immunogenic in sheep, and antibodies produced against them are of no use in antibody therapy. Fragment X probably results from the cleavage of membrane-bound IgM at a site C-terminal to the Cµ3 domain. Fragment X was detected in small amounts in the papain digest of serum IgM. The fragments released by the cleavage of surface IgD with papain were also studied. In the second section, the catabolic rates of rabbit IgG and its fragments in strain two guinea pigs were studied. This was to determine the feasibility of using the monovalent fragment Fab/c and whole IgG in antibody therapy. Whole IgG and Fab/c had similar survival times in guinea pigs, with a half life of around 8 days. Faby fragments were catabolised very rapidly with a half life of a few hours. In the third section, three patients with chronic lymphocytic leukaemia were treated with sheep antibodies directed against the Id on the surface immunoglobulin of their neoplastic cells. In each instance there was partial destruction of the tumour, the extent of which varied from one patient to the other. The effectiveness of they antibody therapy probably depends on many factors including the tumour load, antigenic modulation and the levels of circulating immunoglobulins that carry the tumour Id. The survival time of sheep IgG was determined in each patient.</p
Sulface modified Reduced Graphene Oxide-Sulfur Composite by Polydopamine for Lithium-Sulfur Battery and its Manufacturing Method
No full text본 발명은 황 코팅된 폴리도파민 개질 그래핀 산화물 복합체, 이를 이용한 리튬-황 이차전지, 및 이의 제조방법에 관한 것으로, 보다 상세하게는 용해성 폴리설파이드의 전해질 용출을 억제하여 우수하고 안정적인 수명 특성을 나타낼 수 있는 황 코팅된 폴리도파민 개질 그래핀 산화물 복합체, 이를 이용한 리튬-황 이차전지, 및 이들의 제조방법에 관한 것이다
Preface
No full textPreface: Enabling Technologies for Effective Planning and Management in Sustainable Smart Citie
Positive Electrode for Lithium-Surfur Secondary battery using self-weaved conductive fiber membrane and Method of Manufacturing the Same
No full text본 발명은 자가 엮임된 전도성 섬유막을 이용한 플렉시블 리튬-황 이차 전지용 양극 및 이의 제조방법에 관한 것으로, 보다 상세하게는 부피 변화에 의한 기계적 손상 방지, 리튬 폴리설파이드의 용출 방지, 우수한 전기전도도 효과를 나타내는 플렉시블 페로브스카이트 태양전지 및 이를 제조하는 방법에 관한 것이다
DIKOTOMI HADIS AHAD-MUTAWATIR Menurut Pandangan Ali Mustafa Yaqub
Get PDFDewasa ini orang banyak memperdebatkan kehujjahan hadis do’if, apakah boleh dijadikan landasan beramal atau malah sebaliknya. Mereka melupakan hadis ahad yang jauh pada abad kedua sudah menjadi perdebatan diantara ulama Mu’tazilah dan Ahlusunnah. Al-nadham sebagai ulama dari kelompok Mu’tazilah menganggap bahwa hadis ahad bersifat dhan sehingga tidak dapat dijadikan hujjah dalam hal aqidah, mereka menolak adanya penggunaan hadis ahad. Padahal periwayatan secara ahad tidak bisa terelakkan karena periwayatan hadis pada masa Nabi dengan cepat tersebar ke masyarakat. Para sahabat sangat antusias dalam menerima dan menyampaikan secara bebas hadis yang diterima dari Rasulullah saw. tanpa melihat berapa jumlah jalur orang yang menyampaikannya. Periwayatan secara ahad ataupun mutawatir tidak menjadi perhatian. Untuk mengkaji masalah tersebut maka penulis menggunakan pemikiran Ali Mustafa Yaqub dalam membahas “Dikotomi hadis ahad terdapat bukunya yang berjudul Kritik Hadis. Penting untuk memahami perdebatan tentang hadis ahad tersebut guna menambah wawasan. Menurut analisis penulis hadis ahad tidak bisa ditolak dan tidak dijadikan hujjah dalam masalah akidah, ketika ini dilakukan konsekuensinya banyak hadis yang akan ditolak, seperti tentang syurga dan beraka, dajjal, siksa kubur, mizan di akhirat dll. Hemat penulis adalah pembagian hadis ahad tetap ada dalam disiplin ilmu hadis namun bukan berarti pembagian ini akan menjatuhkan derajat hadis ahad
Pioneers of Library Movement in Pakistan
Get PDFThe paper aims to describe in brief the contribution of seven leaders of Pakistan librarianship, viz. K.B. Khalifa M. Asadullah, Prof. Dr. Abdul Moid, Dr. Abdus Subuh Qasimi, Muhammad Shafi, Fazal Elahi, Khawaja Nur Elahi and S. V. Hussain. The early library developments are given for better understanding of the role of these leaders
Enabling Technologies for Effective Planning and Management in Sustainable Smart Cities
No full textWith the rapid penetration of technology in varied application domains, the existing cities are getting connected more seamlessly. Cities becomes smart by inducing ICT in the classical city infrastructure for its management. According to McKenzie Report, about 68% of the world population will migrate towards urban settlements in near future. This migration is largely because of the improved Quality of Life (QoL) and livelihood in urban settlements. In the light of urbanization, climate change, democratic flaws, and rising urban welfare expenditures, smart cities have emerged as an important approach for society’s future development. Smart cities have achieved enhanced QoL by giving smart information to people regarding healthcare, transportation, smart parking, smart traffic structure, smart home, smart agronomy, community security etc. Typically, in smart cities data is sensed by the sensor devices and provided to end users for further use. The sensitive data is transferred with the help of internet creating higher chances for the adversaries to breach the data. Considering the privacy and security as the area of prime focus, this book covers the most prominent security vulnerabilities associated with varied application areas like healthcare, manufacturing, transportation, education and agriculture etc. Furthermore, the massive amount of data being generated through ubiquitous sensors placed across the smart cities needs to be handled in an effective, efficient, secured and privacy preserved manner. Since a typical smart city ecosystem is data driven, it is imperative to manage this data in an optimal manner. Enabling technologies like Internet of Things (IoT), Natural Language Processing (NLP), Blockchain Technology, Deep Learning, Machine Learning, Computer vision, Big Data Analytics, Next Generation Networks and Software Defined Networks (SDN) provide exemplary benefits if they are integrated in the classical city ecosystem in an effective manner. The application of Artificial Intelligence (AI) is expanding across many domains in the smart city, such as infrastructure, transportation, environmental protection, power and energy, privacy and security, governance, data management, healthcare, and more. AI has the potential to improve human health, prosperity, and happiness by reducing our reliance on manual labor and accelerating our progress in the sciences and technologies. NLP is an extensive domain of AI and is used in collaboration with machine learning and deep learning algorithms for clinical informatics and data processing. In modern smart cities, blockchain provides a complete framework that controls the city operations and ensures that they are managed as effectively as possible. Besides having an impact on our daily lives, it also facilitates many areas of city management
114 terima pingat kebesaran
Get PDFAlor Setar: Timbalan Perdana Menteri Tan Sri Muhyiddin Yassin dan Menteri Besar Kedah Datuk Mukhriz Mahathir mengetuai senarai 114 penerima pingat dan darjah kebesaran Sempena Hari Keputeraan Sultan Kedah Tuanku Abdul Halim Mu'adzam Shah Ke-86, hari ini.Muhyiddin akan menerima Darjah Seri vSetia Abdul Halim Mu'adzam Shah (SHMS) membawa gelaran Datuk Seri Diraja, manakala Mukhriz pula menerima Darjah Seri Paduka Mahkota Kedah (SPMK) membawa gelaran Datuk Seri
- …
