15 research outputs found
Moral Principles in Bama’s Short Story ‘Anthi’
No full textBama, is a prominent leading author of Dalit literature. Her novel Karuku written in 1992 became famous because of its autobiographical elements. She used the language of Dalit people in her writings and it is considered to have paved a new path. She works as a teacher. Her novel Karuku has been translated into English by Lakshmi Holmstrom. She received the 'Cross Wordbook Award' of the year 2000. Bama, who was born in the sixties in Tamil Nadu is currently working as a teacher. Her novels Karuku (1992) and Sangathi (1994) are two of the best Dalit novels. Karuku (Novel-1992), Sangathi (Novel-1994), Vanmam (Novel-2002), Kisumbukkaran (Short Story- 1996), Manushi (Novel) and Thavutu Kuruvi (2019 short- stories) bear great moral thoughts. A short story called ‘Anthi’ has been taken up for analysis in the short stories of Daututuk Kuvi. In this story Bama highlighted the sufferings of lonely old people. Anthi is a short story that captures the life style of the people living with goats and cows. Bama points dignified lifestyle through the lifestyle of Thavasi grandma. In the short story ‘Anthi’ Bama has created a character Thavasi grandma who want to live her life by herself without depending on others. Morality is of the views regarding how one should behave in society. It can be defined as the set of behaviors accepted by a society regarding what is good and what is bad. Morals are not the same in all societies as can be seen in the short story of Anthi through Thavasi grandma. As the problems are different from time to time, according to the development of the society, the stories are created from a critical point of view. This article is about the life style of Thavasi grandma as mentioned in the story ‘Anthi’ by Bama
The cemeteries of Ambracia during the Archaic and Classical period
No full textThe thesis studies the cemeteries of Ambracia, a Corinthian colony in the innards of the Ambracian gulf, during the Archaic and Classical period. As an introduction, it presents the topography of Ambracia, the geomorphology of the area and the different image it presented in antiquity, the countryside with its borders and the city’s urban organization. Following is a brief overview of the history of the city with emphasis on the Archaic and Classical period and a presentation of the history of research of its cemeteries. Then the study deals with the spatial planning and organization of the two cemeteries of Ambracia. In the western cemetery, which is the larger of the two, begins at the end of the 5th c. BC the construction of enclosures, which takes on a more systematic character during the 4th c. BC, making the road that crosses it a real "Gräberstrasse", a formation that remains unique in the region of northwestern Greece. In the eastern cemetery of the city, which is crossed by a smaller road, the tombs are in a rather sparse arrangement, in clusters or pairs. During the Archaic and Classical period the main way of treatment of the dead body is the inhumation, as in most ancient Greek cemeteries. In relation to the inhumations, issues such as the orientation of the dead and the multiple burials in a tomb are analyzed, while in relation to the cremation, the issue of selecting specific types of vessels as funerary urns is discussed, as well as the connection of iconography of red-figure pelikai that were used as funerary urns in the 4th c. BC. In the next chapter are presented the types of tombs that were preferred in each period. As it concerns the grave goods, the vases are examined, which are mainly divided into two big categories, the drinking vessels and the perfume containers, and their burial use is commented. The figurines and the other types of grave goods are also examined, as well as the preference according to the sex of the deceased. Based on the grave goods, two special categories of the dead are commented on: the untimely dead women and the children. The next chapter includes the analysis of the typology of the findings by period and species (pottery, figurines, vases made from other materials, other small objects). The percentage data of the imported and the locally made pottery are presented and the types of all kinds of grave goods are analyzed with bibliographic documentation for their dating. From the summary of the imported pottery it results that during the 6th c. BC Corinthian pottery dominates the burials, to be succeeded by Attic pottery during the 5th c. BC. In the 4th c. BC the local pottery is preferred by, and we follow the evolution of the workshops of Ambracia throughout the Archaic and especially the Classical period. An important subsection is the one that deals with the relations of Ambracia with the West, mainly based on the testimony of the local pottery, while examining the historical data. The last section presents the conclusions for the systematic organization of the burial sites of Ambracia, the special relationship of the burial customs with those of the metropolis Corinth during the Archaic period and the gradual removal from them during the Classical era, the differences from the cemeteries of the villages in the mainland of Epirus and the similarities with those of Lefkas, the other Corinthian colony in the area. It also presents the sequence of Ambracia of the pan-Hellenic trend during the 5th c. BC for uniformity in burials and the gradual emergence of a financially strong social class during the 4th c. BC. It is the time when the city developed into the most important urban center of the wider area, so that at the beginning of the 3rd c. BC it became the capital of the state of King Pyrrhus. The volume with the text of the thesis is accompanied by the volume with the catalog of tombs and finds by era and cemetery and the volume with maps, excavation drawings and photographs of the findings, as well as diagrams.Στη διατριβή μελετώνται τα νεκροταφεία της Αμβρακίας, κορινθιακής αποικίας στον μυχό του Αμβρακικού κόλπου, κατά τους αρχαϊκούς και κλασικούς χρόνους. Αρχικά παρατίθενται στοιχεία για την τοπογραφία της Αμβρακίας, τη γεωμορφολογία της περιοχής και τη διαφορετική εικόνα που παρουσίαζε κατά την αρχαιότητα, την ύπαιθρο χώρα με τα σύνορά της και το άστυ με την πολεοδομική του οργάνωση. Ακολουθεί σύντομη επισκόπηση της ιστορίας της πόλης με έμφαση στους αρχαϊκούς και κλασικούς χρόνους και παρουσιάζεται η ιστορία της έρευνας των νεκροταφείων της. Στη συνέχεια η μελέτη πραγματεύεται τη χωροταξία και την οργάνωση των δύο νεκροταφείων της Αμβρακίας. Στο δυτικό νεκροταφείο, που είναι το μεγαλύτερο από τα δύο, ξεκινά στα τέλη του 5ου αι. π.Χ. η κατασκευή περιβόλων, η οποία λαμβάνει πιο συστηματικό χαρακτήρα κατά τη διάρκεια του 4ου αι. π.Χ., καθιστώντας τη λεωφόρο που το διασχίζει μία πραγματική «Gräberstrasse», διαμόρφωση που παραμένει μοναδική για την περιοχή της βορειοδυτικής Ελλάδας. Στο ανατολικό νεκροταφείο της πόλης, το οποίο διασχίζει μικρότερων διαστάσεων οδός, οι τάφοι είναι σε μάλλον αραιή διάταξη, κατά συστάδες ή ζεύγη. Στις περιόδους αναφοράς της μελέτης ο κύριος τρόπος ταφής είναι ο ενταφιασμός, όπως και στην πλειονότητα των αρχαιοελληνικών νεκροταφείων. Σε σχέση με τους ενταφιασμούς, αναλύονται θέματα όπως ο προσανατολισμός των νεκρών και οι πολλαπλές ταφές μέσα σε έναν τάφο, ενώ σε σχέση με τις καύσεις συζητείται το θέμα της επιλογής συγκεκριμένων τύπων αγγείων ως τεφροδόχων, καθώς και της σύνδεσης εικονογραφίας των ερυθρόμορφων πελικών του 4ου αι. π.Χ. με τη χρήση τους ως τεφροδόχων. Στη συνέχεια παρουσιάζονται οι τύποι των τάφων που προτιμώνται ανά εποχή. Σε σχέση με την κτέριση των ταφών εξετάζονται τα αγγεία ως κτέρισμα, τα οποία χωρίζονται κατά κύριο λόγο σε δύο μεγάλες κατηγορίες, τα αγγεία πόσεως και τα αρωματοδοχεία και σχολιάζεται η ταφική τους χρήση. Εξετάζονται επίσης τα ειδώλια και σχολιάζονται τα άλλα είδη κτερισμάτων, καθώς και η προτίμηση ανάλογα με το φύλο του νεκρού. Με βάση τα κτερίσματα σχολιάζονται δύο ιδιαίτερες κατηγορίες νεκρών: οι άωρες νεκρές και τα παιδιά. Ακολουθεί η ανάλυση της τυπολογίας των ευρημάτων ανά περίοδο και είδος (κεραμική, ειδώλια, αγγεία από άλλα υλικά, άλλα μικροευρήματα). Παρουσιάζονται τα ποσοστιαία δεδομένα της εισηγμένης κεραμικής και των εγχώριων αγγείων που αποσύρονται στους τάφους και αναλύονται οι τύποι όλων των ειδών κτερισμάτων με βιβλιογραφική τεκμηρίωση για τη χρονολόγησή τους. Από τη σύνοψη της εισηγμένης κεραμικής προκύπτει ότι κατά τον 6ο αι. π.Χ. στις ταφές κυριαρχεί η κορινθιακή κεραμική, για να την διαδεχθεί η αττική κατά τον 5ο αι. π.Χ. Κατά τον 4ο αι. π.Χ. προτιμώνται τα αγγεία εγχώριας κατασκευής από τα εργαστήρια της πόλης, την εξέλιξη των οποίων παρακολουθούμε σε όλη τη διάρκεια των αρχαϊκών και κυρίως των κλασικών χρόνων. Σημαντική υποενότητα αποτελεί αυτή που πραγματεύεται τις σχέσεις της Αμβρακίας με τη Δύση, κυρίως με βάση τη μαρτυρία της εγχώριας κεραμικής, εξετάζοντας παράλληλα τα ιστορικά δεδομένα. Στην τελευταία ενότητα παρουσιάζονται τα συμπεράσματα για τη συστηματική οργάνωση των χώρων ταφής της Αμβρακίας, την ιδιαίτερη σχέση των ταφικών εθίμων με αυτά της μητρόπολης Κορίνθου κατά τους αρχαϊκούς χρόνους και τη σταδιακή απομάκρυνση από αυτά κατά τη διάρκεια των κλασικών χρόνων, τις διαφορές από τα νεκροταφεία των κωμών στην ηπειρωτική ενδοχώρα και τις ομοιότητες με τη Λευκάδα, την άλλη κορινθιακή αποικία στην περιοχή, την ακολουθία της πανελλήνιας τάσης κατά τον 5ο αι. π.Χ. για ομοιομορφία στις ταφές και τη σταδιακή ανάδειξη μιας εύρωστης οικονομικά τάξης κατά τη διάρκεια του 4ου αι. π.Χ., όταν η πόλη αναπτύσσεται στο σημαντικότερο αστικό κέντρο της ευρύτερης περιοχής, ώστε να καταλήξει στις αρχές του 3ου αι. π.Χ. πρωτεύουσα του κράτους του Πύρρου. Τον τόμο με το κείμενο της διατριβής συνοδεύει ο τόμος με τον κατάλογο των τάφων και των ευρημάτων ανά εποχή και νεκροταφείο και ο τόμος με τους χάρτες, σχέδια ανασκαφών και τις φωτογραφίες των ευρημάτων, καθώς και γραφήματα
Open Access and Academic Library Public Services: Roles for Reference and Instruction
No full textPaper presented at the IFLA Satellite Preconference: Open Access to Science Information; Trends, Models and Strategies for Libraries, Chania, Crete, Greece. Aug. 6-8, 2010. This paper is published as a chapter in the DeGruyter monograph entitled: Open Access to STM Information: Trends, Models and Strategies for Libraries. Edited by Anthi Katsirikou, Berlin/Munich: De Gruyter Saur, 2011, pp. 29-38.(IFLA Publications; Nr. 153)The published version of the chapter is available in the DeGruyter published monograph available from: http://www.ifla.org/publications/ifla-publications-series-153. http://dx.doi.org/10.1515/9783110263749.2
Blockchain Technology in Supply Chain: conceptual redesign of Crude Palm Oil's trading Business Process
No full textManagement of Technology (MoT
Ethics & Governance of Research: Focus on Research Ethics Committees globally, disparities across regions and the understanding of the structures and systems in place for publicly available information
No full textΤο παρόν άρθρο παρουσιάζει τα αποτελέσματα της έρευνας που υποβλήθηκε για την απόκτηση του μεταπτυχιακού τίτλου: Έρευνα στη βιοοικονομία: βιοτεχνολογία και δίκαιο τον Μάιο του 2022 στο Διεθνές Πανεπιστήμιο της Ελλάδος στη Θεσσαλονίκη. Ο αρχικός σκοπός της έρευνας ήταν η συλλογή πληροφοριών σχετικά με τη συνοχή ή τις ανισότητες που υπάρχουν εθνικό/τοπικό ή περιφερειακό επίπεδο των επιτροπών βιοηθικής και δεοντολογίας. Υπόψη ελήφθησαν διάφορα στοιχεία σχετικά με τα διαρθρωσή τους και λειτουριγκό τους συστήμα όπως: τη διακυβέρνηση, τις τυποποιημένες διαδικασίες λειτουργίας, τις εκπαιδεύσεις και το συστήμα υποβολής εκθέσεων (εσωτερικών αλλά και εξωτερικών εκθέσεων)]. Το αποτέλεσμα αυτής της έρευνας χρησιμεύει επίσης ως βασική γραμμή πληροφοριών ως προς "το αποτέλεσμα της κατανόησης ενός ατόμου (συγγραφέα) προς το τρέχον περιβάλλον με βάση δημόσιων διαθέσιμων πληροφορίων" προκειμένου να φτάσουμε στο επιθυμητό αποτέλεσμα το οποίο είναι η σαφής κατανόηση για τις τρέχουσες διαδικασίες των επιτροπών δεοντολογίας από ένα άτομο χωρίς εκτεταμένη γνώση ή συνεχή έκθεση στο εσωτερικό τους περιβάλλον. Ως εκ τούτου, υπήρξαν δύο στοιχεία που ήταν ταυτόχρονα υπό έρευνα.
Στο παρόν άρθρο παρουσιάζονται τα αποτελέσματα με βάση τα ευρήματα αυτής της έρευνας, αλλά και τα εμπόδια που συμβάλλουν στην κατανόησή τους. Ο συγγραφέας παρέχει τελικές συστάσεις για την οργάνωση των επιτροπών σε θεμελιώδες επίπεδο για την ευθυγράμμιση τους και θέτει αίτημα για σαφήνεια σχετικά με τις υπάρχουσες δημόσια διαθέσιμες πληροφορίες με τρόπο o οποίος να είναι εύκολα κατανοητός στον απλό αναγνώστη, το οποίο συμβάλλει στη διαφάνεια στην έρευνα.This publication presents the findings of the Research submitted for the degree of MRes in Bioeconomy Biotechnology & Law that was conducted in May 2022 at the International Hellenic university in Thessaloniki, Greece. The original research purpose was to gather information on the coherence or disparities that exist in the current environment within the established ethics committees on the country or regional level. Several elements were taken into consideration on their structural systems in place in terms of: governance, standard operating procedures, trainings, and reporting systems (internal but as well as external)] but the outcome of this research serves also as a baseline as “the outcome of a person’s understanding (author) on the current environment based on publicly available information” to reach to the desired result which is to establish a clear understanding on the current procedures of the ethics committees from a person without extensive knowledge or constant exposure to their inner environment. Therefore, there are two elements that were simultaneously under research.
This article presents the results based on the findings of this research but as well the barriers (limitations and restraints) contributing to their understanding. The author provides closing recommendations on the organizational level but as well on a fundamental level to provide alignment but as well as a request for clarity on the existing publicly available information in a manner that is easy to understand to the simple reader which contributes to transparency on research
Proyectar dibujando: Una aproximación fenomenológica al estado naciente del proyecto. Un estudio entre dos culturas arquitectónicas
No full textLa acción del dibujar intenta presentarse en este texto como lenguaje mudo, práctica común general y práctica común en el campo arquitectónico en concreto; y también como acción, apertura, exploración (no representación) en el estado naciente del proyecto. La tesis se presenta como un estudio basado en la experiencia directa, la observación in situ (Practice Based Design Doctórate) intentando reflexionar no desde sus productos alcanzados al dibujar, sino desde la propia acción, enfatizando la dinamicidad del cuerpo como productor de gestos dinámicos. El trabajo busca describir la acción del trazar como apertura, exploración (no representación) en el estado naciente del proyecto. Es el cruce entre la acción experienciada y el pensamiento crítico respecto al hacer con aproximaciones a la artesanía (Sennett, 2010), al placer del dibujar (Nancy, 2013) y la aventura de conformar (Badiou, 2006). La experiencia en el dibujar que este estudio recoge es la desarrollada por la autora en el contexto pedagógico del D.I.G.A. de la E.T.S.A. de Madrid en concreto en las asignaturas “Dibujo Avanzado e Interpretación Gráfica (DAII) I y II” y “Dibujo del Natural” ambas impartidas por el profesor Antonio Verd Herrero y en la participación en los trabajos del Grupo de Investigación y de Innovación Educativa denominado: “Hypermedia” dirigidos por el profesor Javier Seguí, en el periodo que va del año 2007 a la actualidad. La colección de acontecimientos que surgió de esta experiencia y se formó de aproximaciones sucesivas presenta algunos rasgos característicos de la acción del dibujar. Los acontecimientos abordan la acción del dibujar desde una experiencia muda, un tipo de lenguaje, escritura y comunicación común, intercultural pero a la vez impersonal, desde su relación con la escritura, la palabra, el movimiento, el gesto y su imagen. El dibujar se presenta como modo de exploración en la investigación proyectual basada en la arbitrariedad que requiere voluntad, compromiso, ir en contra para participar en cualquier transformación de los límites (físicos, nacionales, sociales, de género, religión, sentido). El dibujar no representativo se presenta como técnica imaginaria radical, “terapia” configural con capacidad para la experimentación con uno mismo (Sloderdijk, 2003), un modo de comunicación intercultural que, sin embargo, siempre recurre al lenguaje verbal, leída e interpretada para cobrar sentido. ABSTRACT The action of drawing is intended to be presented in this text as a mute language, a common practice in general and a common practice in the field of architecture specifically; and also as an action, opening, exploration (not representation) at the birth stage of a project. The thesis forms a study based on a direct observation in an in situ experience (Practice Based Design Doctórate), which intends to reflect not on the products produced by drawing, but on the action itself, emphasizing on the dynamics of the body as a generator of dynamic gestures. The work is the intersection of experienced action and critical thinking related with the making with an approach to a path on craftsmanship (Sennett, 2010), the pleasure in drawing (Nancy, 2013) and the adventure of compromise/ conciliation (Badiou, 2006). The experience in drawing was collected and developed for this study by the author in the context of D.I.G.A. at the E.T.S.A. of Madrid and in particular at the courses of “Advanced Drawing and Graphic Interpretation” (DAII) I y II” and “Life drawing”, together with the active participation and the work of the investigation and Innovation Educational Group “Hypermedia”, coordinated by professor Javier Seguí, during the period starting the year 2007 until the present (2013). The collection of the events derives from a process of successive attempts to approach some characteristic aspects of the action of drawing. The events approach the action of drawing as a mute experience, a kind of language, common communication, writing, gesture and image. Drawing is presented as a way of exploration for a project's investigation, based on arbitrarily and on the asking “what if”. At the same time this process requires will, compromise, opposition in order to participate in a transformation of any kind of limits (physical, national, social, genre, religion, sense). This thesis aims to present non-representative drawing as a radical imaginary technique, a configurational ‘therapy’ with the capacity to experiment with oneself (Sloderdijk, 2003). It can also be considered as a way of intercultural communication which always uses the verbal, readable and interpreted language in order to charge sense
Design, synthesis and antimicrobial activity of usnic acid derivatives (vol 9, pg 870, 2019)
No full textThe authors regret that the author names were not displayed correctly on the original manuscript. The corrected list of authors for this paper is as shown above. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers
Forensic investigation of complex and complicated suicides in Attica, Greece: a 12-year retrospective study
No full textThe purpose of this study was to examine the prevalence and characteristics (victims’ profiles, circumstances surrounding the incidents, and methods employed) of complex and complicated suicides over a 12-year period in the broader area of Athens, Greece. A retrospective analysis of 5,568 autopsy cases performed at the Department of Forensic Medicine and Toxicology of the National and Kapodistrian University of Athens from January 1, 2011, to December 31, 2022, was carried out. Out of a total sample of 5,568 autopsies, 360 suicide cases were identified, among which 14 (3.9%) were classified as complex suicides, and one case (0.3%) was identified as complicated suicide. Among the victims, 78.6% were males. The age range of the victims varied between 25 and 82 years old. The most prevalent method of complex suicide was the use of sharp objects followed by jumping from a height (42.8%). The next most common combination of methods was poisoning (21.4%) along with hanging. Prior suicidal attempts and suicide note were mentioned in 16.7% and 8.3% of the cases respectively. Overall, a total of 9 different methods were used in the above 14 cases. Only half (50.0%) of the victims had an established psychiatric diagnosis. In determining the cause of death in cases of a complex or complicated suicides, it is of utmost importance for the forensic pathologist to gather and analyze all available information provided by the police, the victim’s relatives along with a thorough investigation of the scene, a detailed autopsy and a toxicological analysis. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024
Silencing of the DNA damage repair regulator PPP1R15A sensitizes acute myeloid leukemia cells to chemotherapy
No full textAcute Myeloid Leukemia (AML) is a life-threatening disease whose induction treatment consists of combination chemotherapy with Idarubicin and Cytarabine for fit patients. Treatment failures are frequent, urging the need for novel treatments for this disease. The DNA Damage Response Mechanism (DDR) comprises numerous molecules and pathways intended to arrest the cell cycle until DNA damage is repaired or else drive the cell to apoptosis. AML-derived cell lines after treatment with Idarubicin and Cytarabine were used for studying the expression profile of 84 DDR genes, through PCR arrays. Utilizing de novo AML patient and control samples we studied the expression of PPP1R15A, CDKN1A, GADD45A, GADD45G, and EXO1. Next, we performed PPP1R15A silencing in AML cell lines in two separate experiments using siRNA and CRISPR-cas9, respectively. Our findings highlight that DDR regulators demonstrate increased expression in patients with high cytogenetic risk possibly reflecting increased genotoxic stress. Especially, PPP1R15A is mainly involved in the recovery of the cells from stress and it was the only DDR gene upregulated in AML patients. The PPP1R15A silencing resulted in decreased viability of Idarubicin and Cytarabine-treated cell lines, in contrast to untreated cells. These findings shed light on new strategies to enhance chemotherapy efficacy and demonstrate that PPP1R15A is an important DDR regulator in AML and its downregulation might be a safe and effective way to increase sensitivity to chemotherapy in this disease. © The Author(s) 2024
Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
No full textGlucocorticoids are important for proper organ maturation, and their levels are tightly regulated during development. Here, we use human cerebral organoids and mice to study the cell-type-specific effects of glucocorticoids on neurogenesis. We show that glucocorticoids increase a specific type of basal progenitors (co-expressing PAX6 and EOMES) that has been shown to contribute to cortical expansion in gyrified species. This effect is mediated via the transcription factor ZBTB16 and leads to increased production of neurons. A phenome-wide Mendelian randomization analysis of an enhancer variant that moderates glucocorticoid-induced ZBTB16 levels reveals causal relationships with higher educational attainment and altered brain structure. The relationship with postnatal cognition is also supported by data from a prospective pregnancy cohort study. This work provides a cellular and molecular pathway for the effects of glucocorticoids on human neurogenesis that relates to lasting postnatal phenotypes. © 2024 The Author(s
