301 research outputs found
OB00069 - Gangdhar Stela of the Time of Visvavarman
No full textGangdhar Stela of the Time of Visvavarma
Shaping European identity : the impact of EU related FB group on support and identity growth
No full textauthor: Stela DragovaLiteraturverzeichnis: Blatt 60-61Masterarbeit Universität Salzburg 201
The Reinstallation of the Second Largest Aksumite Stela
No full textThis article deals with the archaeological impact assessment carried out at the town of Aksum in the 1990s by David Phillipson and the Ethiopian archaeologists at the original location of the second largest Aksumite stela before its return from Rome and the result of its reinstallation on its original location in 2008. The author was an assistant excavation supervisor in the large-scale archaeological excavations conducted at the original location of stela 2 in 1997 under the direction of Pro..
Evolution of legislation on stupefying and psychotropic medicines
No full textAbstract. Evolution of legislation on stupefying and its importance in combating of illicit consumption of these substances has been highlighted as a result of a complex synthesis of legislative aspects in the field of drugs on national and international level.Rezumat. A fost evidențiată evoluția legislației în domeniul stupefiantelor și importanța ei în combaterea consumului ilicit de aceste substanțe în
urma unei sinteze complexe a aspectului legislativ în domeniul drogurilor la nivel național și internațional
Asistenţă farmaceutică specializată în farmaciile comunitare: Curs de lecţii şi indicaţii metodice la lucrările practice de laborator pentru studenţii anului 5
No full textThermal aspects of STELA (sustainable thermally enhanced LNAPL attenuation)
No full text2013 Fall.Includes bibliographical references.Extensive bodies of light non-aqueous phase liquids (LNAPLs) are commonly found beneath petroleum facilities. Related concerns include lateral spreading of LNAPL, impacts to groundwater, and impacts to indoor air. Recent studies have shown that natural losses of LNAPL can be on the order of thousands of gallons per acre per year and temperature is a primary factor controlling rates of natural losses. Results of the laboratory and field experiments suggest that LNAPL impacted media in the range of 18-300C can have loss rates that are an order of magnitude greater than media at temperatures less than 18ºC. The vision that has emerged from recent work is that passive thermal management strategies could enhance natural losses of LNAPL and significantly reduce the longevity of LNAPL. Owing to this new understanding, plans were developed for a small-scale field demonstration of sustainable thermally enhanced LNAPL attenuation (STELA) at a former refinery in Wyoming, located adjacent to the North Platte River. The overarching objective of the STELA initiative is to develop a new technology for LNAPLs that is more effective, faster, more sustainable, and/or lower cost than current options. The primary objective of the field demonstration is to collect data needed to evaluate cost and performance at field sites. In November 2011, seventeen multilevel sampling systems were installed in a 10m by 10m area. Preheating temperature and water quality data were collected through the multilevel samplers over a period of 10 months. In August 2012, ten heating elements, including submersible heat trace wires wrapped around 7.6 cm ID PVC pipe with thermostat controls, were installed upgradient of the sampling network to deliver heat to sustain subsurface temperature in an LNAPL body. The heating elements were energized in September 2012. Subsequently, effects of the heating elements on the subsurface temperature were monitored using 17 multilevel sampling systems equipped with 6 thermocouples for 10 months. Preheating data indicates that in the absence of heating, subsurface temperatures are in the range of 18-30°C for 40 days per year. Data collected from September 2012 to July 2013 indicates that with heating, conditions can be maintained in the target range for 60 to 200 days per year depending upon proximity to the heat source. A principle challenge is heat loss to the surface in the winter. Minimum and maximum power inputs have been 15 kw-hr/day and 30 kw-hr/day occurring, respectively in October and May. Assuming an energy cost of 0.10 kw-hr, this equates to costs of 1.5 /day. An independent experiment using Geo-net layer showed that using Gas Permeable Insulation/Heat Sink (GPIHS) system has the potential to enhance the ability of the heating system to sustain temperature beneath the ground surface, and, potentially decrease the power costs. A primary challenge with evaluation and design of STELA systems is anticipating the appropriate spacing of heating elements and necessary energy inputs. Herein this challenge is met by developing a model, calibrated to field data, which can be used to design a full-scale STELA remedies. The overarching objective of the modeling is to demonstrate methods that can be employ to evaluate and/or design full-scale STELA systems. At 5m downgradient of the heating elements, the developed model, accurately, predicted 60 days of the effective season in 2012. Also, the simulation results anticipate that by keeping the heating system activated for three years, the effective season will increase each year. At 5m downgradient of the heating elements, model results suggested 120 days and 150 days of effective season for 2013 and 2014, respectively as compared to 60 days in the first year. The ability of the model to anticipate the effective season for the next years makes the model a useful tool to design and evaluate the future STELA systems. Calibration of the model to the field data shows that exothermic reactions associated with LNAPL losses can change the heat distribution at the system. In addition, the simulation results indicate that the losses at the subsurface are in the range of 5,000 to 10,000gal/acre/yr. These anticipated loss rates are consistent with the previous values reported by McCoy (2012) in 2012 (~900-11,000gal/acre/yr.) A conceptual STELA design is developed in the last chapter to explore the cost of a STELA system at a 1-hectare site. The design is based on condition at the former refinery in Wyoming where the STELA field demonstration was conducted. The cost analysis study indicated that the primary cost is the heating elements installation. The second significant cost is the operation costs, and the third significant cost that can be reduced is the energy source. The cost estimates normalized to common units indicated that the total cost ranges between 720,000 per hectare, 14.4 per cubic meter of treated soil, and 1.5 liter of LNAPL removed depends on the energy source, heating system and the degradation rate. Cost of this magnitude support the hypothesis that STELA has the potential to have cost that is lower than other options employed for LNAPL remediation
Studies on the optimization of the management of the pharmaceutical system in the conditions of health system reform
No full textStructura tezei: introducere, 5 capitole, inclusiv review-ul literaturii, materiale și metode, 3 capitole originale,
concluzii și recomandări, bibliografie din 362 de titluri, 22 Anexe, lucrarea este prezentată pe 439 pagini, inclusiv
197 pagini de text de bază, 57 figuri, 46 tabele. Rezultatele obținute sunt publicate în 90 de lucrări științifice, 1
monografie, 3 manuale de bază, 1 ghid, 3 note de curs, 11 indicații și recomandări metodice.
Cuvinte cheie: management farmaceutic, medicamente, nimicire inofensivă, activitate farmaceutică, servicii
farmaceutice, utilizare rațională, legislație farmaceutică.
Scopul cercetării: Prezentul studiu are ca scop argumentarea direcțiilor manageriale strategice, tactice și
operaționale de perfecționare a sistemului farmaceutic, armonizarea legislației farmaceutice naționale cu bunele
practici ale comunității europene, stabilirea modalităților de realizare și implementare a schimbărilor privind
optimizarea funcționării sistemului farmaceutic pentru îmbunătățirea asistenței farmaceutice acordate populației
în Republica Moldova (RM).
Obiectivele cercetării: 1. Evidențierea importanței managementului farmaceutic în asigurarea dezvoltării
ascendente a sistemului farmaceutic al RM. 2. Analiza reglementărilor domeniului muncii personalului farmaceutic
la nivel național și internațional și evaluarea asigurării sistemului farmaceutic cu cadre farmaceutice. 3. Evaluarea
condițiilor de muncă a farmaciștilor sub diverse aspecte și aprecierea situației actuale privind stabilirea competențelor
profesionale, evidențierea problemelor de ordin social, economic, a situațiilor de conflict și soluționarea lor în
procesul de exercitare a activității farmaciștilor și prestare a serviciilor farmaceutice. 4. Perfecționarea cadrului legal
al sistemului de pregătire profesională a specialiștilor în domeniul farmaciei. 5. Elaborarea Regulilor de Bună
Practică de Farmacie și a nomenclaturii Procedurilor Operaționale Standard pentru diverse locuri de muncă a
farmaciștilor în farmaciile comunitare. 6. Analiza comparativă a Listei medicamentelor esențiale (LME), aprobată
în RM, evaluarea cunoștințelor farmaciștilor, care activează în farmaciile comunitare, în domeniul utilizării LME și
argumentarea propunerilor privind optimizarea procesului de creare și întreținere a LME. 7. Studiul consumului de
analgezice opioide în condiții de staționar de nivel terțiar și ambulator cu scopul argumentării noilor normative de
consum și determinării necesarului în aceste produse. 8. Analiza activității secțiilor de producere ale farmaciilor
comunitare, evaluarea necesității socio-economice și analiza indicatorilor de cost pentru prepararea medicamentelor
conform prescripțiilor individuale și calcularea „Taxei laborum”. 9. Argumentarea dezvoltării sistemului de nimicire
inofensivă a medicamentelor în scopul asigurării funcționalității lui și dezvoltarea reglementărilor privind excluderea
medicamentelor neconforme din circuit, inclusiv prin colectarea lor de la populație. 10. Argumentarea direcțiilor de
reformare a documentelor de politici și elaborarea proiectelor de acte legislativ-normative orientate spre
îmbunătățirea funcționării sistemului farmaceutic al RM.
Rezultatele principial noi pentru știință și practică: În premieră s-a elaborat metoda cuantificării calității
actului farmaceutic din punct de vedere al respectării normelor de etică profesională; s-au evidențiat cauzele
scăderii treptate a prestigiului profesiei de farmacist și s-au elaborat direcțiile de redresare a acestei situații. S-a
perfecționat conceptul și curriculumul de instruire a cadrelor farmaceutice la diverse nivele de studii. S-au
argumentat direcțiile de fortificare a managementului rațional al medicamentelor. S-a optimizat consumul de
analgezice opioide la diverse nivele.
Semnificația teoretică a cercetării: Metodologia abordării sistemice a fost completată cu noi principii și noi
metode de analiză, de cuantificare a factorilor determinanți, noi abordări ale proceselor și fenomenelor
integraționale din cadrul sistemului farmaceutic.
Valoarea aplicativă: Pentru fortificarea activităților practice ale sistemului de sănătate din RM au fost
elaborate: Recomandarea metodică „Estimarea necesităților de opioide utilizate în îngrijirea paliativă” și Foaia de
parcurs „Asigurarea disponibilității morfinei buvabile pentru pacienții care necesită îngrijire paliativă în RM”;
Ghidul privind achizițiile de medicamente și dispozitive medicale pentru instituțiile spitalicești; Metodologia de
calcul a „Taxei laborum” în farmacia comunitară cu funcție de preparare a medicamentelor; Proiecte de
modificare și completare a legislației farmaceutice naționale.
Implementarea rezultatelor științifice: În baza rezultatelor obținute au fost elaborate proiecte de actele
legislative și normative de reglementare a activității sistemului farmaceutic, recomandări metodice și ghiduri
pentru implementare în activitatea întreprinderilor farmaceutice la diverse nivele, precum și în procesul didactic
de instruire a studenților, rezidenților și perfecționare a farmaciștilor la catedrele de profil a facultății de Farmacie
a USMF „Nicolae Testemițanu”.Структура диссертации: введение, 5 глав, включая обзор литературы, материалы и методы, 3 оригинальные
главы, выводы и рекомендации, библиография из 362 наименований, 22 приложение, работа представлена на 439
страницах, из них 197 – основного текста, 57 рисунков, 46 таблиц. Полученные результаты опубликованы в 90
научных публикациях, 1 монографии, 3 базовых учебниках, 1 руководстве, 3 курсовых разработках, 11 указаниях и
методических рекомендациях.
Ключевые слова: фармацевтический менеджмент, лекарственные средства, безопасное уничтожение,
фармацевтическая деятельность, фармацевтические услуги, рациональное использование, фармацевтическое
законодательство.
Цель исследования: Целью данного исследования является аргументация стратегических, тактических и
оперативных управленческих направлений совершенствования фармацевтической системы, гармонизация
национального фармацевтического законодательства с передовой практикой Европейского сообщества,
установление путей реализации и внедрения изменений в части оптимизации функционирования фармацевтической
системы для улучшения фармацевтической помощи населению в РМ.
Задачи исследования: 1. Выявление важности фармацевтического менеджмента в обеспечении развития
фармацевтической системы РМ. 2. Анализ регламентации сферы труда фармацевтических кадров, выявление
социально-экономических проблем в деятельности фармацевтов. 3. Оценка условий труда фармацевтов по
различным критериям и оценка текущей ситуации по формированию профессиональных навыков, выделение
социально-экономических проблем, конфликтных ситуаций и их разрешение в процессе осуществления
деятельности фармацевтов и оказания фармацевтических услуг. 4. Совершенствование законодательной базы
системы профессиональной подготовки специалистов в области фармации. 5. Разработка Правил надлежащей
аптечной практики и номенклатуры стандартных рабочих процедур для различных должностей фармацевтов аптек
открытого типа. 6. Сравнительный анализ Списка Основных Лекарств (СОЛ), утвержденных в РМ, оценка знаний
фармацевтов в области использования СОЛ и аргументация предложений по оптимизации процесса создания и
ведения СОЛ. 7. Изучение потребления опиоидных анальгетиков в стационарных и амбулаторных условиях
третичного уровня с целью обоснования новых норм потребления и определения потребности в этих продуктах. 8.
Анализ деятельности производственных отделов аптек открытого типа, оценка социально-экономической
потребности и анализ ценовых показателей изготовления лекарственных средств по индивидуальным рецептам и
расчета «Taxa laborum» на приготовление лекарств. 9. Аргументация развития системы безвредного уничтожения
лекарственных средств в целях обеспечения ее функциональности и разработки нормативных актов по исключению
из оборота несоответствующих требованиям лекарственных средств, в том числе путем их сбора у населения. 10.
Обосновании направлений реформирования политических документов и разработки законодательно-нормативных
актов, направленных на улучшение функционирования фармацевтической системы РМ.
Принципиально новые результаты для науки и практики: впервые разработана методика количественной
оценки качества фармацевтической деятельности с точки зрения соблюдения норм профессиональной этики;
выявлены причины постепенного падения престижа профессии фармацевта и разработаны направления выхода из
сложившейся ситуации. Усовершенствовались концепция и учебная программа подготовки фармацевтических
кадров различных уровней подготовки. Обоснованы направления усовершенствования рационального менеджмента
лекарств. Оптимизировано потребление опиоидных анальгетиков на различных уровнях.
Теоретическая значимость исследования: Методология системного подхода дополнялась новыми
принципами и новыми методами анализа, количественной оценкой определяющих факторов, новыми подходами к
процессам и интегративным явлениям в фармацевтической системе.
Прикладное значение: В целях усиления практической деятельности системы здравоохранения РМ были
разработаны: Методические рекомендации «Оценка потребности в опиоидах, используемых в паллиативной
помощи» и План действий «Обеспечение доступности перорального морфина для пациентов, нуждающихся в
паллиативной помощи в РМ»; Руководство по закупке лекарственных средств и изделий медицинского назначения
для больничных учреждений; Методика расчета «Taxa laborum» в аптеке открытого типа с функцией приготовления
лекарств; Проекты по изменению и дополнению национального фармацевтического законодательства.
Внедрение научных результатов: На основании полученных результатов подготовлены проекты
законодательных и нормативных актов, регламентирующих деятельность фармацевтической системы,
методических рекомендаций и методических указаний для внедрения в деятельность фармацевтических
предприятий различного уровня, а также в дидактический процесс обучения студентов, резидентов и
усовершенствования фармацевтов на профильных кафедрах фармацевтического факультета ГУМФ им. Николая
Тестемицану.Thesis structure: introduction, 5 chapters, including literature review, material and methods, 3 original
chapters, conclusions and recommendations, bibliography of 362 titles, 22 annexes, the work is presented on
439 pages, including 197 pages of basic text, 57 figures, 46 tables. The obtained results are published in 90
scientific papers, 1 monograph, 3 basic textbooks, 1 guide, 3 lecture notes, 11 indications and methodical
recommendations. Keywords: pharmaceutical management, drugs, harmless destruction, pharmaceutical
activity, pharmaceutical services, rational use, pharmaceutical legislation.
Purpose of the research: The purpose of this research is to argue the strategic, tactical and operational
managerial directions for the improvement of the pharmaceutical system, to harmonize the national
pharmaceutical legislation with the good practices of the European community, to establish the ways of making
and implementing changes regarding the optimization of the functioning of the pharmaceutical system to
improve the pharmaceutical assistance given to the population in the Republic of Moldova.
Objectives of the research: 1. Highlighting the importance of pharmaceutical management in ensuring the
upward development of the pharmaceutical system of the Republic of Moldova. 2. Analysis of the regulations
of the field of work of the pharmaceutical staff at the national and international level and the evaluation of the
provision of the pharmaceutical system with pharmaceutical staff. 3. Evaluation of the working conditions of
pharmacists under various aspects and assessment of the current situation regarding the establishment of
professional skills, the highlighting of social and economic problems, conflict situations and their resolution in
the process of exercising the activity of pharmacists and providing pharmaceutical services. 4. Improving the
legal framework of the professional training system of pharmacy specialists. 5. Elaboration of the Rules of Good
Pharmacy Practice and the nomenclature of Standard Operating Procedures for various jobs of pharmacists in
community pharmacies. 6. Comparative analysis of the List of Essential Drugs (LED), approved in the Republic
of Moldova, evaluation of the knowledge of pharmacists, who work in community pharmacies, in the field of
LED, use and argumentation of proposals regarding the optimization of the LED creation and maintenance
process. 7. The study of the consumption of opioid analgesics in the inpatient and outpatient tertiary level
conditions with the aim of arguing the new norms of consumption and determining the need for these products.
8. Analysis of the activity of the production departments of community pharmacies, assessment of socioeconomic need and analysis of cost indicators for the preparation of medicines according to individual
prescriptions and the calculation of the ”Taxa Laborum” 9. Argumentation of the development of the system of
harmless destruction of drugs in order to ensure its functionality and the development of regulations regarding
the exclusion of non-compliant drugs from the circuit, including by collecting them from the population. 10.
Arguing directions for reforming policy documents and drafting legislative-normative acts aimed at improving
the functioning of the pharmaceutical system of the Republic of Moldova.
Fundamentally new results for science and practice: For the first time, the method of quantifying the
quality of the pharmaceutical act was developed from the point of view of compliance with the norms of
professional ethics; the causes of the gradual decline in the prestige of the pharmacist profession were
highlighted and the directions for the recovery of this situation were elaborated. The concept and curriculum for
the training of pharmaceutical staff at various levels of study has been perfected. Directions for strengthening
rational medication management have been argued. The consumption of opioid analgesics at various levels has
been optimized.
Theoretical significance of the research: The methodology of the systemic approach was completed with
new principles and new methods of analysis, of quantifying the determining factors, new approaches to the
processes and integrative phenomena within the pharmaceutical system.
Applicative value: In order to strengthen the practical activities of the healthcare system in the Republic of
Moldova, the following were developed: A methodical recommendation ”Estimating the needs of opioids used
in palliative care” and the Roadmap ”Ensuring the availability of oral morphine for patients who require
palliative care in the Republic of Moldova”; Guide on the procurement of medicines and medical devices for
hospitals; The methodology for calculating the ”Taxa Laborum” in the community pharmacy with the function
of preparing medicines; Projects to amend and supplement the national pharmaceutical legislation.
Implementation of scientific results: Based on the results obtained, drafts of legislative and normative acts
regulating the activity of the pharmaceutical system, methodical recommendations and guidelines for
implementation in the activity of pharmaceutical enterprises at various levels, as well as in the didactic process
of training students, residents and training of pharmacists at the specialized departments of the Faculty of
Pharmacy of Nicolae Testemitanu University were developed
Abordări conceptuale ale costurilor
No full textCARAMAN, Stela. Abordări conceptuale ale costurilor. In: Contabilitatea şi auditul în contextul integrării economice europene: progrese şi aşteptări = Accounting and audit in the context of european economic integration: advancements and expectations: conf. şt. intern., 5 apr. 2013. Chişinău: S. n., 2013, pp. 245-247. ISBN 978-9975-4242-7-1.This article examines the economic content of the term "cost " based on IFRS. The author motivated the necessity to use this term and presented the main characteristics typical to it. Finally, the author explaind some differences between production costs and cost of production to avoid any confusion that may arise in specifying the content of these terms
Some social and economic aspects of pharmacists work in Republic of Moldova
No full textCatedra Farmacie socială ”Vasile Procpișin”, IP Universitatea de Stat de Medicină şi Farmacie ”Nicolae Testemițanu”Rezumat.
În rezultatul chestionării a 100 farmacişti privind aspectele sociale şi economice ale activităţii lor, s-a demonstrat că în Republica Moldova sunt multe încălcări ale legislației în vigoare privind asigurarea protecției sociale corespunzătoare a specialiștilor în domeniul farmaciei. Analiza datelor obţinute denotă că la angajarea în câmpul muncii nu în toate întreprinderile farmaceutice sunt întocmite contracte
individuale de muncă cu farmaciştii angajaţi, iar cei care au semnat astfel de contracte menţionează că nu este individualizat, fiind unul
tipizat în care se trece doar numele angajatului şi datele personale. Durata zilei de muncă este mai mare de 7 ore pe zi şi doar 58% din
farmaciştii chestionaţi dispun de pauză cu durata de la 15 min până la 30 min. Nu se respectă nici legislația în domeniul protecției sociale a salariaților, astfel, nu se acordă concediu anual plătit sau se acordă pe un termen mai scurt pe motiv de lipsă a cadrelor farmaceutice.Abstract. As a result of questioning 100 pharmacists on social and economic aspects of their work, it was shown that there are many violations of available regulations regarding the ensuring of adequate social protection of specialists in pharmacy legislation in Republic of Moldova. Obtained data show that the employment in some pharmaceutical companies is not based on individual employment contracts and those who signed these contracts said that there is a template one in which are passed only the name and personal dates of the employee. The workday is longer than 7 hours per day and only 58% of surveyed pharmacists have a break lasting from 15 minutes to 30 minutes. There is not a comply with social protection regulations, thus, the paid annual leave is not granted or it is granted for a shorter period of time because there are not enough pharmacists
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