16,284 research outputs found
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
sj-docx-1-tan-10.1177_17562864221074144 – Supplemental material for Intravenous thrombolysis in ischemic stroke patients with a prior intracranial hemorrhage: a meta-analysis
No full textSupplemental material, sj-docx-1-tan-10.1177_17562864221074144 for Intravenous thrombolysis in ischemic stroke patients with a prior intracranial hemorrhage: a meta-analysis by Mahsa Dolatshahi, Mohammadmahdi Sabahi, Shima Shahjouei, Eric Koza, Vida Abedi and Ramin Zand in Therapeutic Advances in Neurological Disorders</p
sj-docx-1-tan-10.1177_17562864241239108 – Supplemental material for Machine Learning-Based Prediction of Stroke in Emergency Departments
No full textSupplemental material, sj-docx-1-tan-10.1177_17562864241239108 for Machine Learning-Based Prediction of Stroke in Emergency Departments by Vida Abedi, Debdipto Misra, Durgesh Chaudhary, Venkatesh Avula, Clemens M. Schirmer, Jiang Li and Ramin Zand in Therapeutic Advances in Neurological Disorders</p
The Convergence of Human and Artificial Intelligence on Clinical Care - Part I
No full textThis edited book contains twelve studies, large and pilots, in five main categories: (i) adaptive imputation to increase the density of clinical data for improving downstream modeling; (ii) machine-learning-empowered diagnosis models; (iii) machine learning models for outcome prediction; (iv) innovative use of AI to improve our understanding of the public view; and (v) understanding of the attitude of providers in trusting insights from AI for complex cases. This collection is an excellent example of how technology can add value in healthcare settings and hints at some of the pressing challenges in the field. Artificial intelligence is gradually becoming a go-to technology in clinical care; therefore, it is important to work collaboratively and to shift from performance-driven outcomes to risk-sensitive model optimization, improved transparency, and better patient representation, to ensure more equitable healthcare for all
The Convergence of Human and Artificial Intelligence on Clinical Care - Part I
No full textThis edited book contains twelve studies, large and pilots, in five main categories: (i) adaptive imputation to increase the density of clinical data for improving downstream modeling; (ii) machine-learning-empowered diagnosis models; (iii) machine learning models for outcome prediction; (iv) innovative use of AI to improve our understanding of the public view; and (v) understanding of the attitude of providers in trusting insights from AI for complex cases. This collection is an excellent example of how technology can add value in healthcare settings and hints at some of the pressing challenges in the field. Artificial intelligence is gradually becoming a go-to technology in clinical care; therefore, it is important to work collaboratively and to shift from performance-driven outcomes to risk-sensitive model optimization, improved transparency, and better patient representation, to ensure more equitable healthcare for all
Avaliação da qualidade de vida de idosos de uma comunidade do Rio Grande do Sul
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2001Este estudo teve como principal objetivo avaliar a qualidade de vida de idosos de uma comunidade do Rio Grande do Sul; através de suas percepções sobre o tema. Após uma revisão de literatura, englobando o envelhecimento propriamente dito, a qualidade de vida e tipos de instrumentos utilizados para avaliar qualidade de vida, a autora propôs um instrumento próprio para a coleta de dados. A pesquisa caracterizou-se como estudo exploratório descritivo, de natureza qualitativa. A técnica utilizada foi à entrevista semi-estruturada e o processo de análise dos dados baseou-se na análise de conteúdo proposta por Bardin. Os achados foram relatados em quatro categorias, discutidas à luz da literatura, abordando as percepções e conceitos dos sujeitos sobre o tema qualidade de vida; qualidade de vida na velhice, a conquista da melhoria da qualidade de vida e o ser idoso por ele mesmo (auto-imagem). Os resultados obtidos permitiram observar as diferenças de opinião a respeito da qualidade de vida do ser humano idoso e sua interação com o meio psicológico, sócio # econômico e cultural, transpassado pelo tênue fio da história de vida de cada um, carregado de experiências e vivências. O estudo demonstrou um vasto campo de atuação da enfermagem e a importância de apreender sobre o envelhecimento e a qualidade de vida e, assim, estabelecer estratégias de atuação cada vez mais voltadas para as singularidades do ser humano em contínuo e natural processo de envelhecimento.The main target of this study was to evaluate life quality of the aged people in a community of Rio Grande do Sul; through their perceptions about the subject. After a review on the literature, which included the growing old process itself, life quality and sorts of instruments used to evaluate it, the author proposed an appropriate instrument for data collecting. The research was characterized as an exploiting and descriptive study, with qualitative nature. The technique used was the semi-structured interview and the process of data analysis was based on the analysis of the contents proposed by Bordin. The findings were related in four categories; they were discussed in the light of the literature, relating to the perceptions and concepts of people about this subject: life quality in old age, the conquest of the improvement in life quality and the aged people by themselves (self-image). Through the results, it was possible to observe the different opinions about life quality of the aged human being and his interaction with the social, economical, cultural and psychological environment, trespassed by the thin thread of each one`s life history, full of experiences. The study showed a large actuation field in nursing activity, and the importance of learning about old process and life quality, and thus, to establish acting strategies aiming more and more at the singularities of the human being, who is in a continuous and natural process of growing old
System-identification of gene regulatory networks by systematic gene perturbation analysis
No full textSystems biology is an interdisciplinary field that combines engineering and molecular biology to better understand the 'design principles' of biological systems. One of the main goals in systems biology is to understand and map complex biological networks. In order to achieve this goal, tools able to process the non-linearity and high dimensionality of biological systems are urgently needed. To develop, test and benchmark tools for investigation of biological processes, it is important to utilize a model system that is able to provide a glimpse of complexity found in higher organisms, and be simple enough such that detailed studies can be performed rapidly, accurately, and reproducibly. Here, we have developed a system-identification framework for the extraction of quantitative and mechanistic information about causal relationship among genes using the canonical galactose utilization pathway in Saccharomyces cerevisiae. This framework, referred to as s&barbelow;ystematic g&barbelow;ene p&barbelow;erturbation a&barbelow;nalysis (SGPA), is based on the effects of systematic pair-wise gene deletions. In essence, the method establishes dynamical models of the regulatory network from single-cell measurements of steady-state input-output relationships, in systematically perturbed networks. SGPA framework is successful in identifying the network structure for the GAL system. This strategy leads the way to a better application of available resources and provides a scalable framework for system-identification and reverse-engineering of biological networks based on in vivo systematic data generation
ARIANA: Adaptive Robust and Integrative Analysis for finding Novel Associations
No full textThe effective mining of biological literature can provide a range of services such as hypothesis-generation, semantic-sensitive information retrieval, and knowledge discovery, which can be important to understand the confluence of different diseases, genes, and risk factors. Furthermore, integration of different tools at specific levels could be valuable. The main focus of the dissertation is developing and integrating tools in finding network of semantically related entities. The key contribution is the design and implementation of an Adaptive Robust and Integrative Analysis for finding Novel Associations. ARIANA is a software architecture and a web-based system for efficient and scalable knowledge discovery. It integrates semantic-sensitive analysis of text-data through ontology-mapping with database search technology to ensure the required specificity. ARIANA was prototyped using the Medical Subject Headings ontology and PubMed database and has demonstrated great success as a dynamic-data-driven system. ARIANA has five main components: (i) Data Stratification, (ii) Ontology-Mapping, (iii) Parameter Optimized Latent Semantic Analysis, (iv) Relevance Model and (v) Interface and Visualization. The other contribution is integration of ARIANA with Online Mendelian Inheritance in Man database, and Medical Subject Headings ontology to provide gene-disease associations. Empirical studies produced some exciting knowledge discovery instances. Among them was the connection between the hexamethonium and pulmonary inflammation and fibrosis. In 2001, a research study at John Hopkins used the drug hexamethonium on a healthy volunteer that ended in a tragic death due to pulmonary inflammation and fibrosis. This accident might have been prevented if the researcher knew of published case report. Since the original case report in 1955, there has not been any publications regarding that association. ARIANA extracted this knowledge even though its database contains publications from 1960 to 2012. Out of 2,545 concepts, ARIANA ranked “Scleroderma, Systemic”, “Neoplasms, Fibrous Tissue”, “Pneumonia”, “Fibroma”, and “Pulmonary Fibrosis” as the 13th, 16th, 38th, 174th and 257th ranked concept respectively. The researcher had access to such knowledge this drug would likely not have been used on healthy subjects.In today\u27s world where data and knowledge are moving away from each other, semantic-sensitive tools such as ARIANA can bridge that gap and advance dissemination of knowledge
Estudio de público: Los esquemas cognitivos sobre la vida conventual femenina novohispana, entre los visitantes de la exposición permanente Monjas Coronadas, del Museo Nacional del Virreinato
No full textLa exposición temporal Monjas Coronadas. Vida conventual en Hispanoamérica, tuvo como objetivo enfatizar la importancia de las fundaciones religiosas hispanoamericanas. En este contexto, era importante conocer los esquemas que el público tiene de la vida conventual y si estos son esquemas estereotipados que pudieran hacer difícil la asimilación de los contenidos que la exposición presentará para ampliar la visión del público sobre este tipo de mujer en el periodo virreinal.</p
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