70 research outputs found
218 - Yusra Mahmood Fundi Obeidat
No full textIncludes bibliographical references.This work describes the development of an integrated sensors system to measure concentrations of dissolved oxygen (DO), pH, glucose, and lactate concurrently at single cell level. DO was measured amperometrically using a three-electrode system of working (WE), counter (CE) and reference (RE) electrodes. pH was measured potentiometrically using two electrodes system of Indium Tin Oxide (ITO) WE and Ag/AgCl RE. Glucose and lactate were measured enzymatically by measuring the current generated from the oxidation of hydrogen peroxide generated from the catalysis of glucose or lactate at the WEs with their catalysis enzymes. A microfluidic chamber containing all four sensors was made using SU8 to investigate single oocytes/embryos immersed in up to 120 µL of respiration buffer. This work includes the results of using the integrated sensors system to measure the metabolic activities of real cells including single oocytes or embryos. The micro-chamber was completely sealed using top layer of ovoil and covered by top glass lid to avoid oxygen exchange between the inside of the chamber and the atmosphere, while being maintained at a temperature of 38.5 ºC to preserve cell viability. The oxygen consumption of cells, the lactate production and glucose consumptions were measured as a change in output current and converted to femto-mol (fmol) per second based on calibrations with buffer of known DO, lactate, and lactate concentrations. This integrated sensor system has some potential applications include evaluating effects of metabolic therapies on oocyte bioenergetics, study the effect of aging on embryos development and monitoring mitochondrial function throughout oocyte maturation and blastocyst development to predict embryo viability to compliment assisted reproductive technologies.Undergraduate Choice - Research Top Scholar
A product formula for certain Littlewood-Richardson coefficients for Jack and Macdonald polynomials
No full textJack polynomials generalize several classical families of symmetric polynomials, including Schur polynomials, and are further generalized by Macdonald polynomials. In 1989, Richard Stanley conjectured that if the Littlewood-Richardson coefficient for a triple of Schur polynomials is 1, then the corresponding coefficient for Jack polynomials can be expressed as a product of weighted hooks of the Young diagrams associated to the partitions indexing the coefficient. We prove a special case of this conjecture in which the partitions indexing the Littlewood-Richardson coefficient have at most 3 parts. We also show that this result extends to Macdonald polynomials.Ph. D.Includes bibliographical referencesby Yusra Fatima Naqv
Analisis Nilai Akidah dalam Novel Inna Ma’al Usri Yusra Karya Muhammad Makhdlori
No full textThe novel Inna Ma\u27al Ausri Yusra is one of the novels that will be discussed more deeply related to the value of faith. The values of faith that will be studied are related to divine values, prophecy, ruhiyat, and samiyat. The method of this research is library research using descriptive analysis method. Based on the results of the analysis of the divine aspect, the author describes Fatimah\u27s faith and piety who has experienced trials and tests. From the aspect of prophecy, the author describes it implicitly and explicitly in the story, about Fatima\u27s determination to achieve high faith even though trials and suffering always befall her, she is guided by the story of the Prophet Muhammad. From the rihiyyat aspect, there is a belief in this value. Azwar is wrong. He believes in spirits. He uses his knowledge to manipulate his patients to comply with their wishes. From the sam\u27iyat aspect, it is illustrated in the story through the Koran, there are five letters consisting of five hadiths that support the arguments of the Koran so that the story has a strong legal basis
A Comparative Study on Ventral Dartos Flap Vs Tunica Vaginalis Flap in Hypospadias Repair, Decreasing the Incidence of Fistula Formation
No full textObjective: To compare the effectiveness of the Tunica Vaginalis Flap (TVF) and the Ventral Dartos Flap (VDF) in
reducing fistula formation following distal hypospadias repair in pediatric patients.
Study Design: Quasi-experimental study.
Place and Duration of Study: This study was conducted at the Department of Paediatric Surgery, Pak Emirates
Military Hospital (PEMH), Rawalpindi, Pakistan from January 2023 to December 2024.
Methods: A total of 100 patients under eight years of age with distal hypospadias were recruited. Patients were
randomly divided equally into two groups (TVF vs VDF), using a random numbers table. Data was analyzed using
SPSS version 27, with chi-square tests for categorical variables and independent t-tests for continuous variables
with significance set at P < 0.05.
Results: The mean age of all patients was 2.46±1.210 years, while the mean weight was 11.47 ± 3.115 kg, and
were comparable between groups. During the 6 months follow-up, a total of 25% (N=25 out of 100) patients
developed Urethro Cutaneous Fistula (UCF), with 13% (N=8) in the TVF group and 34% (N=17) in the VDF group,
indicating a statistically significant reduction in fistula formation with tunica vaginalis flap (P=0.038). The
superior vascularity and independent blood supply of TVF likely contributed to improved wound healing and
fewer UCF.
Conclusion: In this study, TVF provides a more trustworthy neourethral coverage than VDF in distal hypospadias
repair, particularly lowering UCF incidence. These results justify the preferred use of TVF for neourethral
coverage to improve surgical outcomes. However, the choice between the two techniques may depend upon
the operating surgeon's preferences and patient-specific factors. Further large-scale studies with extended
follow-up are recommended to validate these results.
How to cite this: Ahmed R, Ashraf Y, Ahmed A, Jabbar MS, Rehman MH, Jarral S. A Comparative Study on Ventral Dartos Flap Vs Tunica Vaginalis Flap in Hypospadias Repair, Decreasing the Incidence of Fistula Formation. Life and Science. 2025; 6(3): 317-323. doi: http://doi.org/10.37185/LnS.1.1.92
Peran Pimpinan Pondok Pesantren dalam Meningkatkan Penyelengaraan Mutu Pendidikan
No full textIslamic boarding school leaders are the driving force for Islamic boarding school resources. The large role of Islamic boarding school leaders in the process of achieving educational goals means that it can be said that the success or failure of Islamic boarding school activities is largely determined by the quality of the Islamic boarding school leaders themselves. The purpose of this article is to determine the role of Islamic boarding school leaders in improving the quality of education. This research uses library research methods (library research), namely deepening, reviewing and identifying knowledge contained in the literature (reading sources, reference books or other research results). To obtain data the author used sources found in libraries such as books, journals and the internet. The research results show the role of Islamic boarding school leaders in improving the quality of education, namely; Improving the quality of human resources for educators and education personnel, improving the quality of the teaching and learning process, educational facilities and infrastructure
Assessing the influence of an institutional Muslim life program on the Muslim student university experience
No full textInstitutional Muslim life programs at universities in the United States are growing in number and their importance is often highlighted in supporting Muslim university students through avenues like providing a safe space, spiritual education, counseling, and fostering community building with the greater campus. While literature exists on their historical development and presence at universities, minimal research has been conducted on the measured impact that these institutional programs have on Muslim student life experiences. This study aims to fill that void and employs a mixed-methods case study design to examine the influence that one public state university institutional Muslim life program has on the Muslim student experience. Through site observations, a questionnaire, and individual and focus group interviews with students and program administrators, student perceptions of institutional Muslim life and its level of influence were analyzed. With student voices as the main source of data, the findings of this study demonstrate that institutional Muslim life program does in fact influence the Muslim student experience in a variety of ways, including that on a communal, institutional, and personal level. The data showcases that an institutional Muslim life program facilitates for Muslim students to develop greater levels of faith understanding and spirituality and that it also serves as a way to obtain capital. Furthermore, the findings relay that while Muslims in America may be in the midst of a tense and hostile social climate, the primary motivation for most Muslim students to engage with institutional Muslim life programming lies not in countering anti-Muslim sentiment, but in connecting with their faith and spirituality on a personal level. This study provides measured data that Muslim university students do benefit from institutional Muslim life programs and serves as encouragement for educational institutions and administrators to consider supporting and establishing these kinds of institutions within their communities.Ed.D.Includes bibliographical reference
DYNAMICS OF BIOCHEMICAL COMPOSITION IN THE OVARIES OF CAPTIVE-BRED FEMALE RAINBOW TROUT (Oncorhynchus mykiss) DURING GONADAL DEVELOPMENT
No full textThe reproductive biology of rainbow trout (Oncorhynchus mykiss) kept in captivity at Laribal hatchery, Dachigam National park, Jammu and Kashmir was studied from February 2018 to March 2019. This study aims to identify and illustrate developmental stages of oocytes and correlate them with seasonal maturity, gonadosomatic and hepatosomatic indices, and with changes in biochemical composition. Ovarian samples were taken and processed for routine histological analysis. Morphological and anatomical changes of the ovaries were recorded. The oocytes at different developmental stages were observed in the ovaries. The entire reproductive phase was divided into four major divisions: - immature phase, developing phase consisting of growing and maturation phase, spawning phase, and post-spawning phase. The six stages of oocyte development identified in this study include chromatin-nucleolus oocytes, peri-nucleolus oocytes, cortical alveolus oocytes, yolk vesicle oocytes, yolk granular oocytes, and mature oocytes. Maximum gonadosomatic index (12.33 ± 1.04%) and minimum hepatosomatic index (0.82 ± 0.08%) were observed in January, indicating that December- February was the peak spawning period for rainbow trout. It was also observed that June-August was the growing/ immature phase, September-November was the developing phase, and March-May was the post-spawning phase. Furthermore, the biochemical compositions of ninety eight captive rainbow trout ovaries were investigated to determine the broodstock requirements for nutrient-rich feed formulations. The highest moisture (75.30 ± 3.54 %) and crude protein contents (16.10 ± 2.66%) were observed in immature ovaries, while the highest lipid (11.0 ± 2.23%) and ash (2.3 ± 0.60 %) contents were found in developing ovaries. This study revealed the inverse relationship between moisture and lipid. The different biochemical composition of the ovaries at different stages of gonadal development is the key to determine the appropriate broodstock feed formulation at the suitable period of gonadal development. Thus, highly nutritious diet rich in protein and lipids having a high level of digestibility are important for female brooders
BIOCHEMICAL COMPOSITION OF OVARIES AND CHANGES IN BIOLOGICAL INDICES DURING OVARIAN MATURATION IN Schizothorax niger FROM DAL LAKE, KASHMIR
No full textHistological and biochemical studies were conducted on the changes occurring in the ovaries of Schizothorax niger in Dal lake, Jammu and Kashmir from March 2018 to February 2019. This study was aimed to identify ovarian maturation stages histologically and to correlate them with their breeding period, organo-somatic indices and changes in the biochemical composition of the ovary. A total of 120 fish specimens taken were within the range of 24 cm to 43 cm in total length and weight ranging from 115 g to 510 g. Gonadal samples were taken and stained with Haematoxylin and Eosin and were studied under light microscope. Different stages of oocyte development were surveyed and thus, the oocytes identified included primary oocytes, cortical-alveoli oocytes, vitellogenic oocytes, mature oocytes and atretic oocytes. On the basis of presence of different oocytes, five different types of maturity phases were observed which include: Immature, maturing, mature, ripe and spent. During the experimental period, the mean gonadosomatic and hepatosomatic indices in fish exhibited remarkable variation throughout different maturity phases. Maximum gonadosomatic index (15.50 ± 0.75%) and minimum hepatosomatic index (1.87 ± 0.05%) were observed in the month of March indicating peak spawning period for Schizothorax niger. A significant inverse relationship between GSI and HSI was recorded. The single peak in gonadosomatic index during spawning phase (March) reflected that the fish is a spring spawner and an annual breeder. Ovarian biochemical study showed that the lipid (13.36 ± 0.18%) and protein (14.17 ± 0.24%) percentage were highest in spawning phase of ovary, while same were lowest in immature phase. Moisture was found highest (78.12 ± 0.64%) in immature phase and ash was found highest (2.41 ± 0.21%) in mature phase. The results revealed an inverse relationship between moisture and lipid irrespective of their maturity phases. It was concluded that by knowing the accurate breeding season and biochemical changes in ovaries with the progress of maturation we can protect this declining species in natural water bodies by artificial breeding and by formulating the nutrient-rich feed according to the requirement of ovaries at the appropriate phase of reproductive development
Negative Binomial Regression Model Estimation Using Stein Approach: Methods, Simulation, and Applications
No full textThe negative binomial regression model (NBRM) is popular for modeling count data and addressing overdispersion issues. Generally, the maximum likelihood estimator (MLE) is used to estimate the NBRM coefficients. However, when the explanatory variables in the NBRM are correlated, the MLE yields inaccurate estimates. To tackle this challenge, we propose a James–Stein estimator for the NBRM. The matrix mean squared error (MSE) and the scalar MSE properties are derived and compared with other estimators, including the ridge estimator (RE), Liu estimator (LE), and the MLE. We assess the performance of the suggested estimator using two real applications and a simulation study, with MSE serving as the assessment criterion. Results from both simulations and real applications demonstrate the superior performance of the proposed estimator over the RE, LE, and MLE
Kombinasi K-Nearest Neighbor (K-NN) dengan Seleksi Fitur Menggunakan Algoritma Relief-F dalam Klasifikasi Data
No full textiIn several previous studies, accuracy of K-Nearest Neighbor (KNN) iobtained a less ithan maximum accuracy value when compared to other methods. iAs for the causes of ithis, one of which is ibecause ieach iattribute ihas ithe isame iimpact ion ithe iclassification iprocess, iwhile isome characteristics that are iless irelevant cause misclassification in idetermining ithe iclass ifor inew idata. Then iin ithis istudy, the author proposes to K-iNearest Neighbor ithat iattribute iselection ibe icarried iout ito iremove iless irelevant iattributes ibefore icarrying iout ithe iclassification iprocess. iThe iattribute iselection imethod iused iin ithis istudy iis ithe iRelief-F iAlgorithm ias ia imethod ifor attribute iselection whose correlation is not igood ifrom ithe idataset ibeing itested. iThe accuracy iresults iobtained iwill ibe icompared iwith ithe iaccuracy iobtained ifrom ithe iconventional iKNN method using iConfusion Matrix. iThe itest iresults iobtained iare ithat ithe iproposed imethod iis iable ito iincrease ithe iclassification iaccuracy iof iKNN, iwhere ithe iincrease iin iaccuracy iobtained iafter ithe iattribute iselection iis i2.02%.79 HalamanTesis Magiste
- …
