605 research outputs found
The effect of irradiation on black cumin's (Nigella sativa L. )some physicochemical, microbiological properties and composition of fat acids
No full textYüksek LisansÖZETYÜKSEK L SANS TEZIŞINLAMANIN ÇÖREKOTUNUN (Nigella sativa L.) BAZI F Z KOK MYASAL,M KROB YOLOJ K ÖZELL KLER VE YAĞ AS TLER KOMPOZ SYONUNAETK SFerya ARSLAN ÇOLAKTrakya ÜniversitesiFen Bilimleri EnstitüsüGıda Mühendisliği Anabilim DalıDanışman: Doç.Dr. Muhammet ARICIBu araştırmada, ışınlamanın çörekotunun (Nigella sativa L.) bazı fizikokimyasal,mikrobiyolojik özellikleri ve yağ asitleri kompozisyonuna etkisinin belirlenmesiamaçlanmıştır. Piyasadan temin edilen çörekotu örneği 2,5 kGy, 6 kGy, 8 kGy, 10 kGydozlarında ışınlamıştır. Işınlamanın dozu artıkça numunelerin yağ oranı, iyot sayısı,kırılma indeksi ve ransimat değeri gibi fizikokimyasal özelliklerinde azalmagörülmüştür. Yağ asidi kompozisyonunda ise palmitik (C16:0), stearik (C18:0), oleik (C18:1cis), linoleik (C18:2 cis) yağ asitlerinin miktarları azalırken trans formları artmıştır.Işınlama dozu ile ters orantılı olarak tohumların mikroorganizma sayıları azalmıştır.Uygulanan 10 kGy'lik ışınlamayla toplam mezofil canlı bakteri sayısı ile maya ve küfsayısının belirlenemeyecek seviyelere kadar indiği tespit edilmiştir.2006, 42 sayfaAnahtar kelimeler: Çörekotu, ışınlama, mikrobiyolojik özellikler, fizikokimyasalözellikler, yağ asitleri kompozisyonuSUMMARYTHE EFFECT OF IRRADIATION ON BLACK CUMIN?S (Nigella sativa L.)SOME PHYSICOCHEMICAL, MICROBIOLOGICAL PROPERTIES ANDCOMPOSITION OF FAT ACIDS.Ferya ARSLAN ÇOLAKM.Sc. ThesisTrakya UniversityGraduate Scholl of Natural and Applied SciencesDepertmant of Food EngineeringSupervisor:Assoc.Prof. Muhammet ARICIIn this research, it has been aimed to determine the effect of irradiation on blackcumin?s (Nigella sativa L.) some physicochemical, microbiological properties andcomposition of fat acids. The black cumin (Nigella sativa L.) specimen obtained fromthe market has been ırradiationed under 2.5 kGy, 6 kGy, 8 kGy, 10 kgy doses. As muchas dose of irradiation increased, reduction has been observed on the physicochemicalproperties such as fat proportion, number of iodine, index of refraction and value ofransimat of the specimens. In the composition of fatty acids, while the amount ofpalmitic (C16:0), stearic (C18:0), oleic (C18:1 cis), linoleic (C18:2 cis) fat acids decrease,trans forms increased. Microorganism count of the decreased in inverse proportion withthe dose of irradiation. It has been absorved that total count of mezofil alive bacteriatogether with count of yeast and mould reduced to the levels which can not be defined.2006, 42 pageKey words: Black cumin (Nigella sativa L.), irradiation, microbiological properties,physicochemical properties, fatty acid compositio
A SPONTANEOUS CHOLECYSTOCUTANEOUS FISTULA CASE AND ITS MANAGEMENT
No full textCase Report: We report the case of a 62-year-old woman admitted to the Emergency Department with right hypochondrium pain, weakness. On physical examination, she had fever and discomfort of the upper right abdominal quadrant, Ultrasonography and Computed tomography scans revealed cholecystitis findings with the formation of an abscess. Percutan drainage of the purulent collection was carried out under ultrasound guidance. Cholecystectomy was performed after the patient's comorbid diseases were under controlled.Objective: Spontaneous cholecystocutaneous fistula is a rare complication of chronic calculous cholecystitis because currently gallstones are diagnosed and treated at an early stage. This occurrence is possible even if it seems actually to be rare.Conclusion: Owing to early diagnosis and treatment of gallbladder diseases, this condition is rarely seen nowadays. We conclude that percutaneous drainage is a safe and less stressful management technique, especially for elderly patients with co -morbidities before Cholecystectomy.C1 [Arslan, Muhammet] Pamukkale Univ, Radiol, Denizli, Turkey.[Sozuta, Sinan] Healty Sci Univ, Raidol, Adana, Turkey.[Reyhan, Enver] Healty Sci Univ, Gen Surg, Adana, Turkey
Türk Dili ve Anlatım 9. sınıf ders kitabı
No full text#nofulltext# --- Yelten, Muhammet (Arel Author)
Student subjective wellbeing, school functioning, and psychological adjustment in high school adolescents: A latent variable analysis
No full textWell-being is a multi-faceted construct that encompasses all aspects of healthy and successful human functioning across multiple domains. The purpose of the present study was to investigate the predictive power of student subjective wellbeing on several specific adolescent school and psychological adjustment indicators: school achievement, academic satisfaction, prosocial behavior, and internalizing and externalizing problems. Participants included 223 adolescents, comprising of 54.9% girls, ranging in age from 13 to 18 years (M= 15.67, SD= 1.21). Findings from the LVPA indicated that student subjective wellbeing was significantly associated with youth school functioning and adjustment outcomes, ranging from small-to-large effect size (R2 range = .05 to .42). Student subjective wellbeing had the strongest predictive effect on prosocial behavior, followed by academic satisfaction, psychological health problems, and school achievement. With regard to the first-order models, school connectedness and joy of learning significantly predicted student academic satisfaction, prosocial behavior, and psychological adjustment problems. However, the predictive effect of these variables on student school achievement was non–significant. Educational purpose and academic efficacy were significant predictors of all adolescent outcomes. Taken together, these results suggest that student subjective wellbeing is an essential resource for improving youth academic functioning and psychological health
Ibrahim el-Antaki's divan called Burhanul-Burhan-examination and verification
No full textDoktora TeziBu araştırma, Arap ve İslam kültür mirasına katkı sağlamak amacıyla, şair İbrahim el-Antaki'nin (H. 926-M. 1520) "Burhanu'l-Burhan" adlı divanının yazma nüshasını incelemektedir. Başka bir eseri bulunmayan ve çok tanınmayan yazarın bu eseri, araştırmacılar ve muhakkikler tarafından yeterince ele alınmamıştır. Yazarın şiirleri dönemin toplumsal yapısını, halk kültürünü, geleneklerini ve karakteristik özelliklerini yansıtmasına rağmen, eser uzun süre yazarına atfedilmemiştir. Divan, dönemin toplumsal entelektüel seviyesini ortaya koyması ve günümüz kültürüyle karşılaştırma imkânı sunması bakımından önem arz etmektedir. Araştırmada bilimsel inceleme ilkeleri ve tahkik kuralları çerçevesinde yazarın biyografisi, eserin yazara aidiyeti, divanın anlaşılmayan kasidelerinin ve aruz vezinlerinin tespiti, divandaki aruz, dil ve gramer hatalarının tashihi ile şiirlerdeki Beyan ve Bediî sanatlarının özellikleri incelenmiştir.This research examines the manuscript of the divan named "Burhanu'l-Burhan" by poet Ibrahim al-Antaki (H. 926-A.D. 1520) in order to contribute to the Arab and Islamic cultural heritage. This work of the author, who has no other works and is not very well known, has not been sufficiently studied by researchers and scholars. Although the author's poems reflect the social structure, folk culture, traditions and characteristic features of the period, the work has not been attributed to its author for a long time. The divan is important in terms of revealing the social intellectual level of the period and providing an opportunity for comparison with today's culture. In the research, the following issues were addressed within the framework of scientific examination principles and investigation rules: the author's biography, the work's belonging to the author, the detection of the divan's incomprehensible odes and aruz meters, the correction of aruz, language and grammar errors in the divan, and the characteristics of the arts of Beyan and Bediî in the poems were examined
Surgical Treatment of Delayed Diagnosis Left Ventricular Giant Pseudoaneurysm After Myocardial Infarction
No full text1.7.13. Surgical Treatment of Delayed Diagnosis Left Ventricular Giant PseudoaneurysmAfter Myocardial InfarctionAlperen Yıldız 1, Muhammet Ça ˘grı Aykut 1, O ˘guzhan Birdal 2, Eyüp Serhat Çalık 1 andÜmit Arslan 11 Department of Cardiovascular Surgery, Atatürk University Medical Faculty, Erzurum,Türkiye2 Department of Cardiology, Atatürk University Medical Faculty, Erzurum, TürkiyeBACKGROUND: Left ventricular (LV) pseudoaneurysm is a rare but potentiallylethal complication of myocardial infarction (MI). It may also develop following cardiacsurgery, endovascular procedures, or trauma. Multimodality imaging may be required todifferentiate a pseudoaneurysm from a true aneurysm and to plan the surgical treatment.Surgical intervention is required to treat pseudoaneurysm as there is a high risk of rupture.CASE PRESENTATION: A 64 years old male patient applied to our cardiology department with shortness of breath and occasional chest and back pain. The patient had a historyof hypertension, asthma and bladder cancer. The patient underwent coronary angiographyand applied stenting for MI, 7 months before. Echocardiography showed 1.8 × 2.9 mmdefect on the lateral wall and passage through the defect on color Doppler imaging. CTscan confirmed the echocardiographic findings. 138 × 80 × 102 mm cavity related to thedefect was also detected. Surgery was planned. The patient underwent pseudoaneurysmexcision and defect repair with a Teflon patch under cardiopulmonary bypass. He wastaken to ICU post-surgery for 3 days. Postoperative echocardiography showed no passagethrough the defect and no cavity related to the defect. The patient was required long termoxygen therapy and discharged on day ten after the surgery.Keywords: Giant Pseudoaneurysm; delayed diagnosis; myocardial infarction; complication</p
Results from a cervical cancer screening program in Samsun, Turkey
No full textBACKGROUND: Cervical cancer is a preventable disease. This study aimed to share the results of the national cervical cancer screening program performed in primary health care institutions in Samsun between 2015 and 2019. METHODS: Women aged 30–65 years who were screened for cervical cancer in screening centers of Samsun between January 01, 2015, and December 31, 2019, were included in this descriptive study. The data were obtained from the automation program of the “National Human Papilloma Virus (HPV) Laboratory Application” used by the Provincial Directorate of Health Cancer Unit through filtering the completion time of the tests, and all results were evaluated without sampling. Thus, data were presented using descriptive statistics. RESULTS: The mean age of 89,302 women included in the cervical cancer screening program was 45.9 ± 9.0 years. Of the samples obtained from the participants, 1.0% were determined as insufficient material, 94.1% as HPV-negative, and 4.9% as HPV-positive. The most common HPV genotypes were 16, 51, 31, and 52. Of the 4337 HPV-positive women, 74.7% of the pap smear results were negative (including infection, 36.5%), and the most common premalignant lesions were atypical squamous cells of undetermined significance in 7.1% and low-grade squamous intraepithelial lesions in 6.9%. HPV 16/18 was also observed in 31.7% of HPV-positive women. Seven hundred ninety-five women were referred to a specialist physician for further examination and treatment within the scope of the screening algorithm. CONCLUSION: Detecting HPV-positivity by reaching more women within the national cervical cancer screening program’s scope is vital in fighting against this disease. The effectiveness of cancer screening programs should be increased by ensuring community participation through awareness activities
Ultra-trace determination of mercury by platinum-coated tungsten coil trapping cold vapour atomic absorption spectrometry
No full textWithin the scope of this study, a simple, highly sensitive and rapid trapping method for the determination of mercury (Hg) was developed. In this method, the surface of the tungsten coil (W-coil) was coated with platinum using the electrolytic deposition technique. Scanning electron microscopy-energy-dispersive X-ray analyses were performed to examine the surface morphology of Pt-coated W-coil. During the experiment, firstly, Hg vapour generated by tetrahydroborate, used as a reducing agent, was efficiently trapped on the Pt-coated W-coil at collection temperature in hydrochloric acid medium. Subsequently, Hg trapped on the surface of the Pt-coated W-coil was revolatilised by the effect of releasing-stage gases at the optimised releasing temperatures and transported to quartz T-tube atomiser. The experimental conditions have been optimised. Under the optimised conditions, a limit of detection (LOD) of 8.8 ng L-1 was obtained using three times the standard deviation of blank values using Pt-coated W-coil trap cold vapour atomic absorption spectrometry (CVAAS) system. The precision of the measurements was evaluated by relative standard deviation of 4.4%, which is obtained by 11 consecutive measurements of reagent blanks for a collection volume of 6.83 mL corresponding to 90 s collection. The enhancement factors for both LOD (3 s) and characteristic concentration (C-o) were found to be 5.09 and 5.02 when compared with the regular CVAAS system without trap. The accuracy of the proposed method was evaluated by analysing BCR 146 R (Sewage sludge), RTC (Sandy Loam 7), ERM-BD151 (skimmed milk powder) and NIST 1641e (mercury in water) certified reference materials (CRMs). There was a good agreement between certified and found values for all CRMs. The results of the application of the developed method in seawater showed the spike recovery ranges from 94.2% to 102.4%
Primer hiperparatiroidili hastalarda mikrodalga ablasyon tedavisinin etkinliğinin değerlendirilmesinde superb mikrovasküler görüntülemenin rolü
No full textPrimer hiperparatiroidi (PHPT)’ de cerrahi tedaviye alternatif olarak uygulanan mikrodalga ablasyon (MDA) tedavisinde inkomplet ablasyon, operatif başarısızlığa yol açan temel faktörlerden biridir. Günümüzde MDA tedavisi sonrası komplet ve inkomplet ablasyonun değerlendirilmesinde en sık kontrastlı ultrasonografi (US) tercih edilmektedir. Superb mikrovasküler görüntüleme (SMG) ise doku mikrovaskülaritesini hassas şekilde gösterebilen, kontrastlı US’ ye göre non-invaziv, kontrast madde kullanımı gerekmeyen, daha düşük maliyetli ve kolay ulaşılabilir olan yeni bir US tekniğidir. Bu prospektif, kesitsel, tek merkezli ve multidisipliner çalışmanın amacı, PHPT’ de MDA tedavisinin etkinliğinin değerlendirilmesinde SMG’ nin rolünü araştırmaktı.
Çalışmamız yerel etik kurul tarafından onaylandı. Eylül 2022 ile Şubat 2024 tarihleri arasında PHPT nedeniyle MDA tedavisi uygulanan 41 hasta çalışmaya dahil edildi. Tüm hastaların ablasyon öncesinde klinik, laboratuvar ve radyolojik değerlendirmeleri yapıldı. MDA işlemleri izlenerek teknik parametreler ve komplikasyonlar not edildi. MDA sonrası takipte 1.gün, 1.ay ve 6.ayda serum parathormon (PTH) ve kalsiyum düzeyleri ölçüldü. Radyolojik değerlendirme ise 1.ay kontrolünde tekrar yapıldı. Radyolojik değerlendirmelerde US’ de gri skala ile lezyonun lokasyonu belirlenip, maksimum çapı ve hacmi ölçüldükten sonra SMG’ de serbest ROI (Region of Interest) ile lezyon sınırları işaretlenerek vaskülarite indeksleri (VI) ölçüldü. Ablasyon sonrası SMG’ de lezyonda vaskülarite görülmemesi komplet ablasyon olarak tanımlandı ve rezidü vaskülarite görülmesi inkomplet ablasyon olarak değerlendirildi. Klinik başarı, işlemden sonraki 6 aylık takip döneminde hem serum PTH hem de serum kalsiyum düzeylerinin normal aralıkta seyretmesi olarak tanımlandı.
Çalışma yaşları 34 ile 79 arasında değişmekte olan, 35’ i kadın ve 6’ sı erkek olmak üzere 41 hastaya ait 41 paratiroid lezyonu ile yapıldı. MDA tedavilerinin tamamı tek seans olarak gerçekleştirildi. Teknik başarı oranı %100’ dü. SMG’ de lezyonların %75,6’ sında komplet ablasyon ve %24,4’ ünde inkomplet ablasyon saptandı. Klinik
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başarı oranı %53,7 idi. Takipte 6.ayda normokalsemi oranı ise %80,5 olarak saptandı. SMG inceleme bulguları ile klinik başarı arasında istatistiksel olarak anlamlı ilişki saptandı (p=0,002). SMG’ de inkomplet ablasyon saptanan hastalarda klinik başarı oranı (%10), komplet ablasyon saptanan hastalara (%67,7) göre istatistiksel olarak anlamlı düzeyde düşüktü (p=0,002). Klinik başarı sonuçlarına göre SMG’ nin tedavi etkinliğini değerlendirmede duyarlılığı %47,4, özgüllüğü %95,5, pozitif öngörü değeri %90, negatif öngörü değeri %67,7 ve doğruluğu %73,2 olarak hesaplandı. Preablasyon US’ de lezyonların SMG VI düzeyleri ortalama %20,45 ± 9,25 ve medyan %19,55 (aralık, %4 – 52,96) olarak saptandı. Klinik olarak hem başarılı hem de başarısız olan hastalarda, preablasyon US’ ye göre postablasyon US’ de lezyonun maksimum çapı, hacmi ve SMG VI düzeylerindeki düşüşler istatistiksel olarak anlamlıydı (p=0,001). Klinik olarak hem başarılı hem de başarısız olan hastalarda, preablasyon serum PTH ve kalsiyum düzeyine göre postablasyon 1.gün, 1.ay ve 6.ay serum PTH ve kalsiyum düzeylerinde görülen düşüşler istatistiksel olarak anlamlıydı (p0,05). Klinik olarak başarısız olan hastaların preablasyon serum PTH düzeyleri, klinik olarak başarılı olan hastalardan istatistiksel olarak anlamlı düzeyde yüksekti (p=0,014). Klinik olarak başarılı olan hastalarda ortalama MDA gücü, klinik olarak başarısız olan hastalardan istatistiksel olarak anlamlı düzeyde yüksekti (p=0,003).
Sonuç olarak, SMG, PHPT’ de MDA tedavisi sonrası inkomplet ablasyonu gösterebilen ve tedavi etkinliğinin değerlendirilmesine katkı sağlayan etkili bir görüntüleme yöntemi olarak görünmektedir.Incomplete ablation is one of the main factors leading to operative failure in microwave ablation (MWA), which is used as an alternative to surgery for treating primary hyperparathyroidism (PHPT). Contrast-enhanced ultrasonography (CEUS) is commonly used for evaluating complete and incomplete ablation following MWA. Superb microvascular imaging (SMI) is a new ultrasound (US) technique that accurately demonstrates tissue microvascularity. Compared to CEUS, SMI is noninvasive, requires no contrast agents, is more cost-effective, and is easily accessible. This prospective, cross-sectional study, conducted at a single center with a multidisciplinary approach, aimed to investigate the role of SMI in evaluating the efficacy of MWA for PHPT.
Our study was approved by the local ethics committee. A total of 41 patients who underwent MWA for PHPT between September 2022 and February 2024 were included in the study. All patients underwent clinical, laboratory, and radiological assessments before ablation. The MWA procedures were monitored, and the technical parameters and complications were documented. After MWA, all patients were followed up for 6 months. Serum parathyroid hormone (PTH) and calcium levels were measured on the first day, at the first month, and at the sixth month of follow-up after MWA. Radiological assessment was repeated at the first-month follow-up. The radiological evaluations included the assessment of the parathyroid lesion's location, maximum diameter, and volume using gray-scale US. The lesion boundaries were then delineated using a free style ROI (Region of Interest) in SMI, followed by the measurement of the vascularity index (VI). In SMI, post-ablation, the absence of vascularity within the lesion was defined as complete ablation, whereas the presence of residual vascularity was considered indicative of incomplete ablation. Clinical success was defined as maintaining serum PTH and calcium levels within the normal range at the six-month follow-up after MWA.
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The study included 41 parathyroid lesions from 41 patients, consisting of 35 women and 6 men, aged between 34 and 79 years. Each MWA treatment was performed in a single session. The technical success rate was 100%. In SMI, complete ablation was achieved in 75.6% of the lesions, while incomplete ablation was detected in 24.4%. The clinical success rate was 53.7%. At the sixth-month follow-up after the MWA, the normocalcemia rate was 80.5%. A statistically significant relationship was found between SMI findings and clinical success (p=0.002). The clinical success rate in patients with incomplete ablation detected by SMI (10%) was statistically significantly lower than in those with complete ablation (67.7%) (p=0.002). Based on the clinical success outcomes, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of SMI in evaluating MWA efficacy were calculated as 47.4%, 95.5%, 90%, 67.7%, and 73.2%, respectively. In the pre-ablation US, the lesions' SMI VI values ranged from 4 to 52.96%, with a mean of 20.45 ± 9.25% and a median of 19.55%. In both clinically successful and unsuccessful patients, the reductions in the lesion's maximum diameter, volume, and SMI VI in post-ablation US compared to pre-ablation US were statistically significant (p=0.001). In both clinically successful and unsuccessful patients, reductions in serum PTH and calcium levels on the first day, first month, and sixth month post-ablation compared to pre-ablation levels, were statistically significant (p0.05). The pre-ablation serum PTH levels in clinically unsuccessful patients were statistically significantly higher than those in clinically successful patients (p=0.014). The MWA power in clinically successful patients was statistically significantly higher than in clinically unsuccessful patients (p=0.003).
In conclusion, SMI is observed to be an effective imaging method that contributes to the assessment of treatment efficacy by demonstrating incomplete ablation following MWA in patients with PHPT
Malign sebeplere bağlı oluşan opere edilemeyen biliyer tıkanıklıkların semptomatik tedavisinde metalik stentleme öncesi perkütan transhepatik endobiliyer mikrodalga ve radyofrekans ablasyon uygulamasının stent açıklığına etkisinin araştırılması
No full textPerkütan endobiliyer ablasyon (radyofrekans ve mikrodalga ablasyon) tedavileri genellikle malign biliyer darlıklarda metalik stentleme öncesi uygulanan ve stent açık kalma süresini arttırmayı amaçlayan işlemlerdir. Çalışmamızın amacı perkütan endobiliyer ablasyon tedavilerinin uygulanabilirli i ve güvenilirli i ile stent patensi ve hasta sa kalımı üzerine etkisini de erlendirmektir.Çalışmamızda; Eylül 2014 ile Aralık 2020 tarihleri arasında rezeke edilemeyen tümörü olan, malign biliyer obstrüksiyon gelişen ve palyatif tedavi planlanan 122 hasta retrospektif olarak de erlendirildi. Bu hastalardan 13’üne mikrodalga ablasyon sonrası, 8’ine radyofrekans ablasyon sonrası ve 101 hastaya ablasyon yapılmadan metalik stentleme yapıldı ı tespit edildi. Stent tıkanıklı ı gelişen 4 hastaya ise stent içi mikrodalga ablasyon uygulandı ı bulundu. İşlem sonrası hastaların elektronik kayıtlarından klinik, laboratuvar ve radyolojik bulguları de erlendirilerek bilirubin de erleri, stent açık kalma süreleri, hasta sa kalımı, skopi altındaki işlem süresi ve işleme ba lı komplikasyonlar gibi bulgular çalışma cetveline kaydedildi.Ablasyon yapılan ve yapılmayan hasta gruplarını karşılaştırdı ımızda her iki grup arasında stent açıklı ı ya da hasta sa kalımı arasında anlamlı fark bulunamadı. Direkt bilirubin de erlerindeki düşme oranları da her iki grup arasında benzerdi. Komplikasyon oranlarını kıyasladı ımızda ise ablasyon yapılan hasta grubunda komplikasyon oranı daha yüksekti.Elde etti imiz bulgularla metalik stentleme öncesi perkütan endobiliyer ablasyon tedavilerini sadece seçilmiş vakalara öneriyoruz. Perkütan endobiliyer ablasyon tedavi yöntemlerinin hasta genel sa kalımı ve stent açık kalma süresi üzerindeki etkilerini daha net anlayabilmek için homojen özelliklere sahip daha fazla sayıda hasta içeren randomize kontrollü prospektif klinik çalışmalar gerekmektedir.Percutaneous endobiliary ablation (radiofrequency and microwave ablation) treatments are generally applied before metallic stenting in malignant biliary strictures and aim to increase the stent patency time. The aim of our study is to evaluate the feasibility and safety of percutaneous endobiliary ablation treatments, and their effect on stent patency time and patient survival.In our study; between September 2014 and December 2020, 122 patients who developed malignant biliary obstruction due to an unresectable tumor and were scheduled for palliative treatment were retrospectively evaluated. Metallic stenting was performed in 13 of these patients after microwave ablation, 8 after radiofrequency ablation, and in 101 patients without ablation. In 4 patients who developed stent occlusion, it was found that in-stent microwave ablation was applied. After the procedure, from the electronic records of the patients; clinical, laboratory and radiological findings, bilirubin values, stent open times, patient survival, duration of the procedure under fluoroscopy and procedure-related complications were recorded in the study chart.When we compared the patient groups with and without ablation, no significant difference was found between the two groups in terms of stent patency or patient survival. The reduction rates in direct bilirubin values were also similar between the two groups. When we compared the complication rates, the complication rate was higher in the patient group who underwent ablation.With our findings, we recommend percutaneous endobiliary ablation treatments before metallic stenting only for selected cases. In order to better understand the effects of percutaneous endobiliary ablation treatment methods on patient overall survival and stent patency, randomized controlled prospective clinical studies with larger numbers of patients with homogeneous characteristics are required
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