1,720,992 research outputs found
Multi-Knowledge: Collaborative Environments for the Extraction of New Knowledge from Heterogeneous Medical Data Sources
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Metabolic syndrome: What are the acknowledged markers, and how reliable are they?
No full textInsulin resistance and its cluster of associated abnormalities, defined as the metabolic syndrome, are important coronary heart disease (CHD) risk factors. The report of the Adult Treatment Panel-III (ATP III) serves as a formal recognition of this, and the fact that approximately 25% of Western populations may be suffering from the untoward consequences of insulin resistance emphasizes the magnitude of the clinical problem. The aim of the definition of the metabolic syndrome based on ATP III criteria is to provide a tool able to identify insulin-resistant individuals, and it offers a pragmatic approach to the early identification of individuals at risk for CHD, with the potential benefit of a more aggressive lifestyle intervention and a more focused follow-up
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Peer-to-Peer Infrastructures for Multi-Knowledge Workflows
No full textThe general aim of the Multi-Knowledge project is to develop a collaborative environment to allow networks of co-operating medical research centres to create, exchange and manipulate new knowledge from heterogeneous data sources. The Multi-Knowledge service-oriented architecture (MK-SOA) will enable workflow design and execution based on novel operating procedures to manage and combine heterogeneous data and make them easily available for the imputation of study algorithms. In this paper we focus on the peer-to-peer infrastructure we have developed to support the creation of a fully decentralized collaborative environment, in which each party remains autonomous and the interactions between services are seen from a global perspective
Pulmonary Complications in Diabetes Mellitus: The Role of Glycemic Control
No full textInsulin deficiency induces an increase in blood glucose levels that, in long run, becomes toxic for many organs and systems. Microangiopathy and derangements in the immune function are known consequences of hyperglycemia, but the way in which these systemic alterations may affect pulmonary function has been scarcely investigated. Although confirmation from large clinical trials is still to come, the diabetic disease seems to hit the pulmonary microcirculation as any other organ by increasing vessel wall thickness and impairing gas exchange, which leads to a measurable loss of function and respiratory efficiency. In addition, a diabetic lung is more susceptible to low respiratory tract infections by atypical microorganisms and more likely to host severe episodes of pneumonia than a normal, non-diabetic lung. This is a review of current knowledge on the impact of diabetes mellitus in lung health. We have paid special attention to the role of metabolic control in preventing damage to the lung by sustained hyperglycemi
INTEGRATION OF CLINICAL, HISTOPATHOLOGICAL, RADIOLOGICAL AND BIOMOLECULAR DATA FOR PREDICTION OF ORAL CANCER RECURRENCE: THE NEOMARK PROJECT'S FIRST REPORT.
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