1,354,290 research outputs found
Inflation targeting : una discusión dedicada al caso argentino
No full textFil: Amodei, Maximiliano. Universidad de San Andrés. Departamento de Economía; Argentina.El siguiente trabajo se propone describir propiedades del régimen de metas de inflación y estudiar cómo se encuentra la Argentina con relación a las precondiciones básicas que la literatura considera que deben estar presentes previo a la implementación de este esquema monetario. El foco estará puesto en poner en discusión el caso argentino a la luz de diferentes aportes de la literatura académica
Canti della resistenza spagnola : 1939-1961
No full textConté: Lato A: Canzone di Bourg-Madame, Giá Passó L'estate, Sensa pena, Da quando Franco e la Falange ..., Morte nella cattedrale / cantano: Michele L. Straniero e Margot ; accompagnati da F. Amodei -- Lato B: In Spagna I fiori..., Nubi e speranze , Strofette, Canzone di page, Una canzone / cantano: Michele L. Straniero e Margot ; accompagnati da F. Amode
Thyroidectomy and Its Complications: A Comprehensive Analysis
No full textBackground/Objectives: This study aims to assess the rate of complications in patients who underwent thyroid surgery and were monitored post-operatively to explore potential correlations between various parameters that may aid in clinical decision making. Methods: An observational retrospective study was conducted on patients who underwent thyroid surgery and were followed up in our Endocrinology Unit. Patients were selected based on strict criteria. The following data were collected: sex; age; type of thyroid disease; pre-operative symptoms due to thyroid pathology; surgical procedures; post-operative complications; histopathological diagnosis; and post-operative blood levels of TSH, PTH, vitamin D, and calcium. Results: Among 340 patients, 25.29% had benign thyroid disease. Total thyroidectomy was performed in 89.4% of cases. Recurrent laryngeal nerve injury was found in 32 patients. Hypocalcemia occurred in 14 patients within 24 h post-operatively. Histopathological examination identified incidental parathyroid tissue in 5.88% of thyroidectomy specimens. Post-operative hypoparathyroidism was observed in 26 patients, and vitamin D deficiency in 68 patients. Conclusions: The study demonstrated that thyroid surgery is quite a safe procedure; however, complications may occur. A statistically significant correlation was found between the type of surgery and the risk of vocal fold palsy, without correlation with the type of thyroid disease. A thorough pre-operative evaluation by a multidisciplinary team may help reduce the risk of post-operative complications. Despite the extensive knowledge of thyroid surgery, small refinements may further improve surgical outcomes
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Metabolic comorbidities of adrenal insufficiency: Focus on steroid replacement therapy and chronopharmacology.
No full textAdrenal insufficiency (AI) is characterized by higher mortality and morbidity compared with the general population. Conventional replacement steroid therapy, currently recommended for the treatment of AI, is associated with increased frequency of metabolic comorbidities due to daily overexposure. By contrast, dual-release hydrocortisone is associated with a decreased risk of metabolic comorbidities, providing an adequate release of hydrocortisone and mimicking the physiological profile of cortisol. These favorable effects are due to a reduced daily steroid exposure that does not affect the expression of the clock genes which are involved in metabolic pathways and are regulated by the normal physiological circadian rhythm of endogenous cortisol. This narrative review focuses on the possible metabolic comorbidities of AI due to steroid replacement therapy, which evaluates the effects of conventional and novel drugs with attention to chronopharmacology
Very Low-Calorie Ketogenic Diet: A Potential Application in the Treatment of Hypercortisolism Comorbidities
No full textA very low-calorie ketogenic diet (VLCKD) is characterized by low daily caloric intake (less than 800 kcal/day), low carbohydrate intake (<50 g/day) and normoproteic (1-1.5 g of protein/kg of ideal body weight) contents. It induces a significant weight loss and an improvement in lipid parameters, blood pressure, glycaemic indices and insulin sensitivity in patients with obesity and type 2 diabetes mellitus. Cushing's syndrome (CS) is characterized by an endogenous or exogenous excess of glucocorticoids and shows many comorbidities including cardiovascular disease, obesity, type 2 diabetes mellitus and lipid disorders. The aim of this speculative review is to provide an overview on nutrition in hypercortisolism and analyse the potential use of a VLCKD for the treatment of CS comorbidities, analysing the molecular mechanisms of ketogenesis
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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