3 research outputs found
PEMBERIAN ENZIM PAPAIN DALAM PAKAN TERHADAP GAMBARAN HISTOLOGI USUS BENIH IKAN PERES (OSTEOCHILLUS KAPPENI)
No full textABSTRAKTujuan penelitian ini adalah untuk mengetahui pengaruh pemberian enzim papain dalam pakan terhadap gambaran histologi usus benih ikan peres. Penelitian ini dilaksanakan pada bulan September hingga bulan Oktober 2015 yang bertempat di Balai Benih Ikan (BBI) Lukup Badak, Aceh Tengah dan Laboratorium Histologi Fakultas Kedokteran Hewan Universitas Syiah Kuala. Metode yang digunakan dalam penelitian ini adalah metode eksperimental menggunakan rancangan acak lengkap (RAL) dengan 5 perlakuan dan 3 ulangan. Perlakuan dalam penelitian berupa pemberian enzim papain dengan konsentrasi yang berbeda. Hasil penelitian menunjukkan bahwa penambahan dosis papain yang berlebihan dalam pakan ikan peres akan membuat makanan akan lebih lama mengalami proses pencernaan, sehingga berpengaruh terhadap proses penyerapan makanan. Hal ini terlihat pada perubahan ukuran vili usus ikan peres. Dampak pemberian enzim papain optimum 2% dibuktikan dengan gambaran histologi yang menunjukkan kinerja organ yang efektif.Kata Kunci: Ikan peres, enzim papain, histologi usus, kualitas air
Markets Equilibrium: The Is-Lm Model
No full text. The purpose of this study is to analyze how the concept of markets equilibrium: the IS-LM Model. This research uses library research method by using reference sources from books and journals according to the theme. The author uses a qualitative method which is explained graphically, namely the market balance of the IS-LM model where the focus is on money and goods markets associated with macroeconomics where researchers take the side of investors. The results of this study are that the balance in the economy is the point where the IS and LM curves intersect. This point provides an interest rate (r) and income level (Y) that satisfies the equilibrium conditions that occur in the goods market and money market. In other words, planned spending equals actual spending, and the demand for real money balances equals the supply. So that the IS-LM balance, it is stated that IS=LM
Allogeneic Hematopoietic Stem Cell Transplantation in Immunodeficiency—Centromeric Instability—Facial Dysmorphism (ICF) Syndrome: an EBMT/ESID Inborn Errors Working Party Study
No full text\ua9 The Author(s) 2024.Immunodeficiency–Centromeric instability–Facial dysmorphism (ICF) syndrome is an inborn error of immunity characterized by progressive immune dysfunction and multi-organ disease usually treated with antimicrobial prophylaxis and immunoglobulin substitution. Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment, but data on outcome are scarce. We provide a detailed description of disease characteristics and HSCT outcome in an international cohort of ICF syndrome patients. Eighteen patients (including all four genotypes) were enrolled. Main HSCT indications were infections (83%), enteropathy/failure to thrive (56%), immune dysregulation (22%) and myelodysplasia/haematological malignancy (17%). Two patients underwent pre-emptive HSCT after early diagnosis. Patients were transplanted between 2003–2021, at median age 4.3 years (range 0.5–19), after myeloablative or reduced-intensity conditioning, from matched sibling or matched family donors, matched unrelated or mismatched donors in 39%, 50% and 12% of cases respectively. Overall survival was 83% (all deaths occurred within the first 5 months post-HSCT; mean follow-up 54 months (range 1–185)). Acute GvHD occurred in 35% of patients, severe (grade III) in two (12%), while none developed chronic GvHD. At latest follow-up (median 2.2 years (range 0.1–14)), complete donor chimerism was achieved in 15/17 surviving patients. All survivors demonstrated normalized T and B cell numbers. Immunoglobulin substitution independence was achieved in all but two patients. All survivors recovered from pre-transplant infections, enteropathy/failure to thrive and immune dysregulation. All three patients transplanted at young age (≤ 3 years), after early diagnosis, survived. The favourable clinical and immunological HSCT outcome in this cohort of patients supports the timely use of this curative treatment in ICF syndrome
