1,721,207 research outputs found
Nerve growth factor delays retinal degeneration in C3H mice
No full textThe aim of the present study was to investigate the biological role of nerve growth factor (NGF) on retinal degeneration in the C3H mouse strain. This strain is characterized by a single gene mutation (rd) which leads to photoreceptor degeneration resembling human retinitis pigmentosa
Dati acquisiti ed ipotesi emergenti sul ruolo delle Neurotrofine, in particolare dell’NGF, in patologie di natura psichiatrica
No full textNematode diseases of the Aloe L. genus species in greenhouses of Donetsk Botanical Garden, National Academy of Sciences of Ukraine
Full text linkПри помощи методов нематологического мониторинга выяснены причины заболеваний представителей рода Aloe L. в оранжереях Донецкого ботанического сада. Определен видовой состав фитонематод, выявлены возбудители заболеваний, описаны симптомы. Впервые определены пороги вредоносности двух видов паразитических нематод для видов рода Aloe L.При помощи методов нематологического мониторинга выяснены причины заболеваний представителей рода Aloe L. в оранжереях Донецкого ботанического сада. Определен видовой состав фитонематод, выявлены возбудители заболеваний, описаны симптомы. Впервые определены пороги вредоносности двух видов паразитических нематод для видов рода Aloe L
Nematode diseases of the Aloe L. genus species in greenhouses of Donetsk Botanical Garden, National Academy of Sciences of Ukraine
No full textПри помощи методов нематологического мониторинга выяснены причины заболеваний представителей рода Aloe L. в оранжереях Донецкого ботанического сада. Определен видовой состав фитонематод, выявлены возбудители заболеваний, описаны симптомы. Впервые определены пороги вредоносности двух видов паразитических нематод для видов рода Aloe L.При помощи методов нематологического мониторинга выяснены причины заболеваний представителей рода Aloe L. в оранжереях Донецкого ботанического сада. Определен видовой состав фитонематод, выявлены возбудители заболеваний, описаны симптомы. Впервые определены пороги вредоносности двух видов паразитических нематод для видов рода Aloe L
Deux nouvelles espèces d' Aloe L. (Xanthorrhoeaceae, Asphodelaceae), section Lomatophyllum Rowley, de Madagascar
No full textJean-Philippe Castillon (2017): Deux nouvelles espèces d' Aloe L. (Xanthorrhoeaceae, Asphodelaceae), section Lomatophyllum Rowley, de Madagascar. Adansonia 39 (1): 7-13, DOI: 10.5252/a2017n1a
Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-alpha, interleukin-1 beta and cholecystokinin-8: the possible role of NGF in the inflammatory response.
No full textOBJECTIVE:
Aim of this study was to investigate the synthesis, release and effects of nerve growth factor (NGF) in human synovial cells isolated from synovial tissue specimen from healthy and osteoarthritis (OA) patients.
METHODS:
Human synovial fibroblasts cultures were established starting from healthy and osteoarthritis patients. NGF protein levels in the culture medium, NGFmRNA and high-affinity NGF receptor (Tyrosine kinase A: TrkA) expression in the cells were evaluated in basal conditions and after stimulation with pro-inflammatory cytokines or with the neuropeptide cholecystokinin-8 (CCK-8). The effect of NGF supplement to culture medium on cell proliferation, TrkA expression, and tumour necrosis factor-alpha (TNF-alpha) and inducible-nitric oxide synthase (iNOS) production was investigated.
RESULTS:
Under basal conditions human synovial cells produce and release NGF. Both interleukin-1-beta (IL-1 beta) and TNF-alpha, but not CCK-8 promote NGF synthesis and release from OA cells. TrkA NGF receptors are also expressed in both normal and OA synovial cells. NGF, but not IL-1 beta, TNF-alpha and CCK-8, enhances the expression of TrkA in isolated synovial cells. NGF down-regulates IL-1 beta-induced TNF-alpha and iNOS production by OA synovial fibroblasts.
CONCLUSIONS:
NGF is produced and released and TrkA receptors are expressed in synovial inflammation. Overexpression of NGF in inflammed joints might be involved in the modulation rather than in the induction of the joint inflammatory response
Topical treatment with nerve growth factor restores trophic corneal ulcers
No full texthttp://hdl.handle.net/20.500.11768/9684
The expanding role of nerve growth factor: from neurotrophic activity to immunologic diseases
No full textAtlas of leaf surface micromorphology in Aloe L. (Asphodelaceae) from the Horn of Africa region
No full textFentaw, Eshetu, Elliott, Kelda F.V.A., Demissew, Sebsebe, Cutler, David, Grace, Olwen M. (2021): Atlas of leaf surface micromorphology in Aloe L. (Asphodelaceae) from the Horn of Africa region. Phytotaxa 524 (4): 261-282, DOI: 10.11646/phytotaxa.524.4.
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