1,720,968 research outputs found
Evaluation of efficacy and tolerability of four weeks bifonazole treatment after nail ablation with 40% urea in mild to moderate distal subungual onychomycosis
No full textThe aim of this study was to verify efficacy and tolerability of sequential therapy with 40% urea paste followed by 1% bifonazole urea in mild to moderate distal subungual onychomycosis of the toenails
Le unghie dei piedi. Manuale pratico per la gestione delle onicopatie. Ediz. ampliata
No full textLe malattie delle unghie rappresentano un settore specialistico della dermatologia e sono spesso poco conosciute. In particolare, le onicopatie dei piedi rappresentano oggi un campo in cui dermatologo e podologo collaborano al fine di garantire un’ottimale gestione del paziente, che può così beneficiare di diagnosi e terapia di competenza specialistica, ma anche di trattamenti periodici da parte del podologo.
L’intento di questo libro è fornire una visione schematica e immediata delle patologie ungueali, facilitata dalla presenza di numerose fotografie, per rendere il lettore in grado di effettuare una pronta diagnosi e gestire il paziente nel modo più opportuno.
In questa seconda edizione è stato aggiunto un focus sulle unghie delle mani, che possono presentare patologie esclusive e diverse da quelle dei piedi
la dermatite da contatto: frequente complicanza delle ulcere croniche degli arti inferiori
No full textdermatite da contatto nelle ulcer
An open clinical investigation on clinical dermatoscopy, OCT and RCM visible effects of application of a new topical product for 6 months on brittle nails and weak nails with rough surface and/or tendency to break
Full text linkIntroduction & Objectives
Nail brittleness is a common complaint characterized by weak nails with rough surface and/or tendency to split, flake and crumble. This nail alteration can be a consequence of factors that alter the nail plate production or factors that damage the nail plate, such as cosmetics (permanent and non-permanent nail lacquers), psoriasis, lichen planus, ageing, chemotherapy, other drugs and anaemia.
The aim of our study was to evaluate the effectiveness, tolerability and patient’s compliance of a new water-soluble nail lacquer with silicon and keratin synthesis booster product for brittle and weak nails.
Material & Methods
30 patients of both sexes, aged >18 years, affected by nail brittleness were prescribed a new topical therapy to be applied on the affected nails once a day for 6 months. The new product is dispensed by a pencil unit with a brush and has to be applied on the entire edge of the nail, cuticle included. Periodic evaluation of treatment efficacy was performed by standardized photography and dry video-dermoscopy of the target nail at baseline (V1), after 15 days (V2), 1 month (V3), 3 months (V4) and 6 months (V5). The treatment efficacy was evaluated by the experimentator through Global and Trichoscopy Assessment Scale and by patients through a patient global assessment and a specify questionnaire. 10 patients also underwent to Optical Coherence Tomography (OCT) in order to have a further objective parameter of efficacy evaluation.
Results
All patients concluded the study, with marked improvement of nail weakness and appearance. No side effects were recorded. All patients judged the treatment easy to apply and effective.
Conclusions
This new water-soluble nail lacquer with silicon and keratin synthesis booster is an effective and safe option for the treatment of nail brittleness and damages
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Application and comparison between non-invasive and invasive methods in the study of skin annexes diseases
Full text linkIntroduzione
Lo scopo dello studio è valutare l’accuratezza diagnostica delle metodiche strumentali non invasive, in particolare dermoscopia, tomografia a coerenza ottica (OCT ) e microscopia confocale (RCM), nelle patologie degli annessi cutanei, confrontate con le metodiche invasive (biopsia ed exeresi chirurgica).
Materiali e metodi
È stato effettuato uno studio prospettico osservazionale in pazienti afferenti all’ambulatorio di Malattie degli Annessi Cutanei, dell’U.O. di Dermatologia dell’Azienda Ospedaliero - Universitaria di Bologna IRCCS Policlinico di Sant’Orsola, Dipartimento di Medicina Specialistica Diagnostica e Sperimentale (DIMES) dell’Università di Bologna, della durata di tre anni. Le metodiche di OCT e RCM sono state effettuate c/o il Policlinico di Modena, U.O. Dermatologia. Le patologie incluse comprendono malattie dei capelli e malattie ungueali. La prima parte dello studio si è focalizzata sullo studio delle metodiche non invasive, la seconda parte si è basata sulla conferma istologica del sospetto diagnostico inziale. Nella terza parte dello studio si è effettuato un confronto tra le diverse metodiche e una valutazione dell’accuratezza diagnostica delle stesse nelle malattie dei capelli e delle unghie.
Risultati
Sono stati valutati 231 pazienti (135 con diagnosi di malattie dei capelli e del cuoio capelluto; 96 con malattie delle unghie). In specifico, siamo riusciti a stabilire una corrispondenza tra i parametri tricoscopici, istologici e RCM per l’alopecia fibrosante frontale, l’alopecia areata incognita, la tinea capitis e il lichen simplex cronico. Nell’ambito delle malattie delle unghie, abbiamo valutato le correlazioni tra onicoscopia ed OCT per il lichen planus ungueale, la psoriasi ungueale, l’onicomicosi e il tumore glomico.
Conclusioni
Riteniamo lo studio molto utile, in quanto reputiamo che una conoscenza ancora più approfondita degli strumenti non invasivi per la diagnosi precoce di malattie degli annessi cutanei sia importante a diversi livelli, come ad esempio sui tempi di diagnosi e sulla riduzione dei costi di gestione.Introduction
The purpose of the study is to evaluate the diagnostic accuracy of non-invasive instrumental methods, in particular dermoscopy, optical coherence tomography (OCT) and confocal microscopy (RCM), in the skin appendages disorders, compared with invasive methods (biopsy and surgical excision).
Materials and methods
A prospective observational study was performed in patients belonging to the Outpatient Department of Skin Annexes Diseases, of the Dermatology Unit of the Hospital - University of Bologna IRCCS Policlinico di Sant’Orsola, Department of Specialized Diagnostic and Experimental Medicine (DIMES) of the University of Bologna, lasting three years. The OCT and RCM methods were carried out at the Policlinico di Modena, Dermatology Unit. Evaluated diseases included hair diseases and nail diseases. The first part of the study focused on the study of non-invasive methods, the second part was based on the histological confirmation of the initial diagnostic suspicion. In the third part of the study, a comparison was made between the different methods and an evaluation of their diagnostic accuracy in hair and nail diseases.
Results
231 patients were evaluated (135 diagnosed with hair and scalp diseases; 96 with nail diseases). Specifically, we were able to establish a correspondence between the trichoscopic, histological and RCM parameters for frontal fibrosing alopecia, alopecia areata incognita, tinea capitis and chronic lichen simplex. In nail diseases, we evaluated the correlations between onychoscopy and OCT for nail lichen planus, nail psoriasis, onychomycosis and glomus tumor.
Conclusions
We believe that the study is very useful, as we believe that an even deeper knowledge of non-invasive tools for the early diagnosis of skin annexes diseases is important at various levels, such as for example on diagnosis times and reduction of management costs
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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