187 research outputs found
Design Esperienziale per il Patrimonio Culturale. Un’applicazione partecipativa per il Museo Cola Filotesio di Amatrice in Paesaggio Urbano
No full textIl Museo di Amatrice, raso al suolo dal terremoto del 2016, raccoglieva opere provenienti dal territorio amatriciano ma anche materiali sulla storia dell’edificio e sulla città di Amatrice. Il progetto di ricerca prevede di rappresentare e diffondere parte del patrimonio perduto attraverso un sistema immersivo e interattivo finalizzato al coinvolgimento esperienziale e alla diffusione dei contenuti del Museo in modalità visual storytelling; si sta inoltre progettando una Biblioteca Vivente Digitale, una installazione interattiva per rendere viva la storia orale del territorio attraverso le testimonianze dirette dei cittadini
Fetal placental inflammation is associated with poor neonatal growth of preterm infants: a case-control study.
No full textAbstract Objective: To determine whether there is an association between histological chorioamnionitis (HCA) and postnatal growth of preterm infants in the neonatal period. Method: This case-control study is part of a larger prospective histological study on placentas performed in all deliveries prior to 32 weeks of gestation. Eligible cases involved all placentas with a diagnosis of HCA. Control subjects were those without HCA, matched 1:1 with case subjects according to gestational age (±1 week). Placental inflammatory status and serial weight gain were analyzed for all infants during the first four postnatal weeks. Based on placental inflammation extension, HCA was defined as maternal HCA (MHCA) or fetal HCA (FHCA). Results: Of the 320 mother-infant pairs, 71 (22.1%) presented with HCA (27 MHCA and 44 FHCA). Decreases in weight gain at 21 and 28 days were associated with the presence of FHCA (β coefficient ± SE = -4.40 ± 2.21, p = 0.05 and -6.92 ± 2.96, p = 0.02, respectively), whereas no significant differences were found between MHCA and no-HCA groups. FHCA and MHCA were not identified as risk factors of weekly weight gain, after adjusting for possible confounders (maternal ethnicity, parity, smoking during pregnancy, infant gender, IUGR status, SGA status, antenatal steroids, total fluid intake, late-onset sepsis, BPD). Conclusions: We found an association between fetal placental inflammation and poor neonatal growth but we were not able to identify a specific week wherein weight gain could be mostly affected. Placental findings may be used to identify preterm infants at risk of postnatal growth failure
Relationship between the neonatal white blood cell count and histologic chorioamnionitis in preterm newborns.
No full textOBJECTIVE: The aim was to examine the relationship between neonatal white blood cell (WBC) count and the diagnosis of histologic chorioamnionitis (HCA).
DESIGN: We measured WBC, a widely used marker of inflammation, to evaluate whether the values at birth were associated with HCA. Setting: NICU, Department of Pediatrics of Padua University, Padua, Italy.
SUBJECTS: WBC count was evaluated in 71 preterm neonates (<32 weeks of gestation) with HCA and in a control group without HCA on day 1, 3, and 6 after delivery. Logistic regression analysis and diagnostic accuracy analysis were used to assess the association between WBC counts and HCA.
MAIN RESULTS: WBC levels were significantly higher in infants with HCA than in those without HCA (Median IQR, WBC (x10(9)/l): day 1, 13.2 (6.2-21.8) vs 8.1 (6-11.4), p < 0.001; day 3, 17.4 (11.4-26.9) vs 6.3 (5.2-8.3), p < 0.001; day 6, 18.4 (11.1-31) vs 6.5 (4.4-9), p < 0.0001). The neonatal WBC count on the third day of life was the most sensitive parameter associated with HCA (sensitivity: 0.80; specificity: 0.88). The cut-off value based on the ROC curve was 10 (x10(9)/l).
CONCLUSIONS: WBC count in the third day of life is strongly associated with HCA
Relationship between the neonatal white blood cell count and histologic chorioamnionitis in preterm newborns.
No full textObjective: The aim was to examine the relationship between neonatal white blood cell (WBC) count and the diagnosis of histologic chorioamnionitis (HCA). Design: We measured WBC, a widely used marker of inflammation, to evaluate whether the values at birth were associated with HCA. Setting: NICU, Department of Pediatrics of Padua University, Padua, Italy. Subjects: WBC count was evaluated in 71 preterm neonates (< 32 weeks of gestation) with HCA and in a control group without HCA on day 1, 3, and 6 after delivery. Logistic regression analysis and diagnostic accuracy analysis were used to assess the association between WBC counts and HCA. Main results: WBC levels were significantly higher in infants with HCA than in those without HCA (Median IQR, WBC (x10(9)/l): day 1, 13.2 (6.2-21.8) vs 8.1 (6-11.4), p < 0.001; day 3, 17.4 (11.4-26.9) vs 6.3 (5.2-8.3), p < 0.001; day 6, 18.4 (11.1-31) vs 6.5 (4.4-9), p < 0.0001). The neonatal WBC count on the third day of life was the most sensitive parameter associated with HCA (sensitivity: 0.80; specificity: 0.88). The cut-off value based on the ROC curve was 10 (x10(9)/l). Conclusions: WBC count in the third day of life is strongly associated with HCA
Nasal and Tracheal Microbial Colonization in Laryngectomized Patients
No full textComplete separation of upper and lower respiratory tract after total laryngectomy results in loss of physiological nasal functions and presence of "unconditioned" inspired air in lower airways. Aim of this study is evaluating the presence of a microbial colonization of nasal cavities and trachea in laryngectomized long-term survivors.METHODS:
Twenty-five laryngectomized patients underwent symptoms' anamnestic evaluation, endoscopic fiber optic nasal and tracheal examination, specimen collection for microbiological exam, and culture. Enrolled patients had at least a 2-year follow-up period in order to evaluate long-term microflora.
RESULTS:
Gram positive polimicrobic flora represented the main finding in nasal cavities and trachea (92% and 48% of patients, respectively). Other bacteria were non-fermenters Gram negative bacteria, Enterobacteriaceae and Staphylococcus aureus. The same microflora was demonstrated in nasal cavity and trachea in 5 patients (20%), while sterile nasal cavity and trachea were seen in 3 (12%) and 4 (16%) cases, respectively. No fungi were observed in nasal cavity and trachea.
CONCLUSION:
Nasal cavities and trachea of laryngectomized patients are colonized by nonpathogenic and/or potentially pathogenic bacteria, in absence of signs and symptoms of infection. Colonizer microflora should be kept in mind when a culture from nasal or tracheal swabs is needed in daily practice
Achieving access to justice in the European area of justice : a contribution to the resolution of cross-boarder commercial disputes
No full textL’Union européenne connaît un nombre croissant de litiges commerciaux transfrontières (conflits entre professionnels ou entre un professionnel et un consommateur). Ces différends doivent pouvoir être résolus par la partie qui le demande afin qu’elle puisse voir ses droits substantiels se réaliser. Il est donc essentiel de garantir l’accès à la justice, étatique ou privée, au sein de l’Espace européen de justice. À cette fin, l’Union européenne dispose d’une compétence partagée afin d’adopter des mesures facilitant l’accès à la justice (art. 67 §4 Traité FUE). Considéré comme un objectif et un droit fondamental, l’accès à la justice est concrétisé à travers le droit de la coopération judiciaire de l’Union. Son analyse révèle aussi bien la richesse de la notion que les lacunes de sa réalisation. Dans cette perspective, il convient de se demander comment l’Espace européen de justice peut véritablement atteindre l’objectif d’accès à la justice pour permettre la résolution des litiges commerciaux transfrontières.The European Union experiences a growing number of cross-border commercial disputes (between professionals or between a professional and a consumer). These litigations shall be resolved at the demand of the claimant, so s/he can enjoy his/her substantial rights. Hence, it is essential to guarantee access to justice, whether public or private, within this European area of justice. To this end, the EU has a shared competence to adopt rules facilitating access to justice (art. 67 §4 Treaty FEU). Considered as an objective and a fundamental right, access to justice shall be realized through judicial cooperation law of the Union. This analysis shall reveal its richness as well as its lacuna. Therefore, one must determine how the European area of justice shall reach this objective of access to justice to allow the settlement of cross-boarder commercial disputes
Décision d'exemption au bénéfice d'entreprises de haute technologie
No full textInternational audienceDécision de la Commission européenne du 12 janvier 1990 relative à une procédure d'application de l'article 85 du Traité CEE (IV/32.006 - Alcatel Espace / ANT Nachrichtentechnik) (90/46/CEE
Lamy droit économique : concurrence, distribution, consommation
No full textInternational audienceno abstrac
Market Definition as an instrument in Competition Law : Study in the light of European and Vietnamese Law
No full textLa délimitation du marché pertinent est l’un des outils les plus importants dont disposent les autorités de la concurrence pour examiner et évaluer les problèmes de concurrence. Mais elle est également le sujet le plus ardu du droit de la concurrence et a fait l’objet de vifs débats entre les juristes et les économistes depuis des décennies. La question n’a jamais été résolue une fois pour toute. En effet, depuis le début de cette décennie, le professeur Louis KAPLOW, le plus récent parmi les plus hostiles à la délimitation du marché, a remis en question cette procédure tout en faisant valoir qu’elle devrait être abandonnée. À la même période, les deux économistes Carl SHAPIRO et Joseph FARRELL ont proposé le test Up Ward Pricing Pressure (UPP) comme alternative à la délimitation du marché pour apprécier les fusions ayant lieu sur des marchés de produits différenciés. Plusieurs tests dérivés suivant le même principe ont ensuite été élaborés. Les débats ont pris cette fois-ci une dimension plus fondamentale, en particulier lorsque les autorités américaines de la concurrence ont révisé en 2010 les Horizontal Merger Guidelines en adoptant l’approche selon laquelle l’analyse d’une fusion ne doit pas nécessairement débuter par la délimitation du marché. Ces évolutions aussi importantes posent la question de savoir comment le droit européen de la concurrence devrait réagir. La délimitation du marché devrait-elle demeurer l’étape préalable déroute analyse de la concurrence ou doit-elle être remplacée par d’autres méthodes quantitatives ? Lorsque le marché pertinent joue un rôle d’instrument d’analyse dans tous les domaines du droit européen (entente, abus de position dominante et contrôle des concentrations), quelles seraient les conséquences juridiques de son abandon pur et simple ? Dans une autre perspective, la réfutation des nouvelles méthodes économiques aurait-elle des répercussions lorsque dans certains marchés spécifiques, la délimitation du marché à l’aide du test du monopoleur hypothétique (TMH) ne serait pas celle qui permet d’évaluer au mieux les effets anticoncurrentiels ? La délimitation du marché pertinent en fonction uniquement de la substituabilité du côté de la demande dans la pratique actuelle de la Commission européenne est-elle une approche pertinente ? Dans le contexte où la notion de marché pertinent est désormais communément utilisée dans la quasi-totalité des pays où il existe un droit de la concurrence, l’impact que l’évolution du droit européen, l’un des plus avancés du monde, peut avoir sur les autres ne doit pas être sous-estimé. Le droit vietnamien de la concurrence en est un, d’autant plus qu’il s’inspire des principes du droit européen ainsi que de son modèle administratif.Market definition is one of the most important analytical tools used by the competition authorities to examine and evaluate competition problems. But it is also the most difficult subject of competition law and has been the subject of heated debate between lawyers and economists for decades. The issue has never been resolved once and for all. Indeed, since the beginning of this decade, Professor Louis Kaplow, the most recent “hostile proponent” to market definition, has questioned this procedure while arguing that it should be abandoned. At the same time, the American economists Carl Shapiro and Joseph Farrell propose an economic method named Upward Pricing Pressure as an alternative to market definition in analyzing the competitive effects of mergers in markets with differentiated products. Several derived tests following the same principle were developed. The current debate seems to have taken on a more fundamental dimension, in particular since 2010 when the US competition authorities revised the Horizontal Merger Guidelines which state that market definition is not necessarily the first step in a merger analysis. These important developments raise the question how European competition law should react. Should market definition remain a prerequisite for any competition analysis or should it be replaced by other quantitative methods? While the relevant market plays a role as an instrument of analysis in all areas of European competition law (cartel, abuse of dominant position and merger control), what would be the legal consequences of abandoning it altogether? From another perspective, could the exclusion of new economic methods have any repercussions incases, such as in certain specific markets, where the definition of the relevant market using the hypothetical monopolist test (TMH) would not be the best way to assess anticompetitive effects? Is market definition based only on demand-side substitutability, in the current practice of the European Commission, an appropriate approach? In the context where the concept of relevant market is now commonly used in almost all countries where competition law exists, the impact that the evolution of European law, being one of the most advanced in the world, can have on others should not be underestimated. Vietnamese competition law would certainly be impacted as it is based on the principles of European law and its administrative model
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