854 research outputs found
La spugna è la mia anima. Omaggio a Piero Ceccucci
No full textL'iniziativa di questo volume nasce dall'affetto e dalla stima sinceri di molti colleghi italiani e stranieri che hanno accolto con entusiasmo l'idea di rendere omaggio all'amico e collega Piero Ceccucci e alla sua lunga carriera di professore universitario. Il presente testo prende spunto da un verso di Fernando Pessoa tradotto da Ceccucci all'interno del suo volume "Il mondo che non vedo"
Proposal to measure the rare decay K+- -> pi+ nu anti-nu at the CERN SPS
No full textWe propose to measure the very rare kaon decay K + → π + ν ν at the CERN SPS to make a decisive test of the Standard Model by extracting a 10% measurement of the CKM parameter |Vtd |
Expression of Interest to measure rare kaon decays at the CERN SPS
No full textCERN-SPSC-2004-010 publicatio
Letter of Intent to measure the rare decay K+ -> pi^+ nu nu-bar at the CERN SPS
No full textCERN-SPSC-2004-029 publicatio
Self-assembling nanowires from a linear L,D-peptide conjugated to the dextran end group
No full textPreparation and characterization of a block-like L,D-octapeptide-dextran conjugate DEX29-(L-Val-D-Val)4 self-assembling into nanowire structures is reported. The conjugate was prepared by solid phase click-chemistry on an alkyne group N-terminus functionalized peptide with a regularly alternating enantiomeric sequence. Low molecular weight dextran (Xn = 29) with moderately low dispersity (1.30) was prepared by controlled acid hydrolysis and dialysis with selected cut-off and functionalized with an azido group on the reducing end by reductive amination. The strong hydrogen bonds and hydrophobic interactions of the (L-Val-D-Val)4 linear peptide drive the conjugate to self-assemble into long (0.1–1 μm) nanowires. To our knowledge, this is the first example of a peptide-polysaccharide conjugate that can self-assemble into a nanowire architecture
Identification of remodeled collagen fibers in tumor stroma by FTIR Micro-spectroscopy: A new approach to recognize the colon carcinoma
No full textThe tumor stroma plays a pivotal role in colon cancer genesis and progression. It was observed that collagen fibers in the extracellular matrix (ECM) of cancer stroma, undergo a strong remodeling. These fibrous proteins result more aligned and compact than in physiological conditions, creating a microenvironment that favors cancer development. In this work, micro-FTIR spectroscopy was applied to investigate the chemical modifications in the tumor stroma. Using Fuzzy C-means clustering, mean spectra from diseased and normal stroma were compared and collagen was found to be responsible for the main differences between them. Specifically, the modified absorptions at 1203, 1238, 1284 cm−1 and 1338 cm−1 wavenumbers, were related to the amide III band and CH2 bending of side chains. These signals are sensitive to the interactions between the α-chains in the triple helices of collagen structure. This provided robust chemical evidence that in cancer ECM, collagen fibers are more parallelized, stiff and ordered than in normal tissue. Principal Component Analysis (PCA) applied to the spectra from malignant and normal stroma confirmed these findings. Using LDA (Linear Discriminant Analysis) classification, the absorptions 1203, 1238, 1284 and 1338 cm−1 were examined as spectral biomarkers, obtaining quite promising results. The use of a PCA-LDA prediction model on samples with moderate tumor degree further showed that the stroma chemical modifications are more indicative of malignancy compared to the epithelium. These preliminary findings have shown that micro-FTIR spectroscopy, focused on collagen signals, could become a promising tool for colon cancer diagnosis
La spugna è la mia anima
No full textLa spugna è la mia anima. Omaggio a Piero Ceccucci (“The sponge is my soul. Tribute do Pietro Ceccucci”) is a work born from the sincere affection and esteem of many Italian and foreign colleagues who enthusiastically welcomed the idea of paying homage to their friend and colleague Piero Ceccucci and to his long career as a university professor of Portuguese and Brazilian language and literature at various Italian universities, such as Perugia, Milan, University “Bocconi” of Milan, Genoa and Florence. This volume aims to be a fair recognition of the commitment and dedication that Prof. Piero Ceccucci has addressed to the teaching of Portuguese language and literature in Italy, but also to remind him the gratitude of University of Florence, to which, we are sure, he will always be tied
Dr Julia King CBE FREng, Chief Executive Designate, Institute of Physics (United Kingdom), visiting the NA48 experiment.
No full textPhoto 02: Visiting the NA48 experiment, Dr Julia King, Chief Executive Designate, Institute of Physics (Britain and Ireland) (right) with A. Ceccucci and K. Peach. Photo 05: Visiting the NA48 experiment, Dr Julia King, Chief Executive Designate, Institute of Physics (Britain and Ireland) (centre) with A. Ceccucci and C. Lazzeroni. Photo 08: Visiting the NA48 experiment, Dr Julia King, Chief Executive Designate, Institute of Physics (Britain and Ireland) (second from left) with (left to right) R. Barlow, J. Wood, N. McCubbin, K. Peach, A. Ceccucci, C. Lazzeroni, M. Patel and D. Munday
Cogito. Ergo lusitanus (non) sum. António Sérgio: dalla polemica sul Seicentismo al Reino Cadaveroso
No full textIl razionalismo filosofico di António Sérgio esercita una saggistica nuova e dirompente per il suo "polemismo" all'interno del dibattito culturale, politico e filosofico della prima metà del Novecento portoghese. Il saggio mira a ricostruire le tappe della radicale critica che il filosofo rivolge al Seicento portoghese come momento iniziale di decadenza culturale, politica, scientifica e economica del Paese dentro l'orizzonte europeo
A glass spherical Cherenkov counter based on total internal reflection
No full textWe built and tested a Cherenkov counter for particle identification , with spherical shape (R=600 mm), made of glass. The threshold at B= 0,92 is set by mechanism of total internal reflection of the Cherenkov ligh
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