1,723,388 research outputs found
Trykk 8902
Full text link8902 med tittel: Ekspedisjonsbestemmelser for befordring av gods og levende dyr i samtrafikk med utlandet ; internasjonal godstrafik
Complete Invariant ⋆-Metrics on Semigroups and Groups
No full textIn this paper, we study the complete ⋆-metric semigroups and groups and the Raǐkov completion of invariant ⋆-metric groups. We obtain the following. (1) Let (X,d⋆) be a complete ⋆-metric space containing a semigroup (group) G that is a dense subset of X. If the restriction of d⋆ on G is invariant, then X can become a semigroup (group) containing G as a subgroup, and d⋆ is invariant on X. (2) Let (G,d⋆) be a ⋆-metric group such that d⋆ is invariant on G. Then, (G,d⋆) is complete if and only if (G,τd⋆) is Raǐkov complete
Pre-clinical studies of a new quinolone (UB-8902) against Acinetobacter baumannii resistant to ciprofloxacin
No full textThe in vitro activity and in vivo efficacy of a new ciprofloxacin derivative (UB-8902) were evaluated. In vitro time-kill curves were performed for ciprofloxacin (CIP), moxifloxacin (MXF) and UB-8902 against CIP-susceptible (Ab58) and CIP-resistant (Ab661 and Ab33) Acinetobacter baumannii strains. UB-8902 showed similar bactericidal activity to CIP and MXF against these strains. In the in vivo experiments in mice, the toxicity of UB-8902, its 50% protective dose (PD50) (peritoneal sepsis model), its pharmacokinetic/pharmacodynamic (PK/PD) parameters and its efficacy in a pneumonia model were studied. The maximum tolerated dose of UB-8902 was 512 mg/kg. PD50 values were 16, 128 and 32 mg/kg for Ab58, Ab661 and Ab33, respectively. Pharmacokinetic parameters of UB-8902 were similar to MXF and were lower than those for CIP, whilst pharmacodynamic parameters were better than CIP. In the pneumonia model, UB-8902 decreased the bacterial lung concentration [4.62 colony-forming units (CFU)/g and 4.15 log10 CFU/g] and positive blood cultures (60% and 62.5%) for Ab58 and Ab33, respectively, compared with the control. In conclusion, UB-8902 presents bactericidal activity against A. baumannii strains resistant to CIP. Moreover, it is effective at reducing mortality in a model of peritoneal sepsis with a dose lower than the toxic one, and it is efficacious in a murine pneumonia model. © 2011 Elsevier B.V. and the International Society of Chemotherapy.This study was supported by the Spanish Ministry of Science (PETRI 0957-OP to JV), by 2009 SGR 1256 from the Departament d’Universitats, Recerca i Societat de la Informació de la Generalitat de Catalunya, and by the Ministerio de Ciencia e Innovación, Instituto de Salud Carlos III—co-financed by the European Development Regional Fund ‘A way to achieve Europe’ ERDF, Spanish Network for the Research in Infectious Diseases (REIPI RD06/0008). This work has also been supported by funding from the European Community (AntiPathoGN contract HEALTH-F3- 2008-223101).Peer reviewedPeer Reviewe
Linked collectors and determiners for: Symphyla Collection - Instituto Nacional de Pesquisas da Amazônia (INPA).
No full textNatural history specimen data linked to collectors and determiners held within, "Symphyla Collection - Instituto Nacional de Pesquisas da Amazônia (INPA)". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/9e0936f9-8902-4a4b-8f32-a3e3b038993d">https://bionomia.net/dataset/9e0936f9-8902-4a4b-8f32-a3e3b038993d</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/9e0936f9-8902-4a4b-8f32-a3e3b038993d">https://gbif.org/dataset/9e0936f9-8902-4a4b-8f32-a3e3b038993d</a>. Formatted as a Frictionless Data package
California Poll: 8902 -- April 13-22, 1989
No full textThe Field Poll, established in 1945 as The California Poll by Mervin Field, has operated continuously as an independent, non-partisan, media-sponsored public opinion news service. Each year the Field Polls cover a wide range of political and social topics examining California public opinion. Continuing measures are made of voter support for leading political figures vying for major state and federal offices, job ratings of important political figures and reactions to significant political events. Voter awareness, understanding and predispositions of major campaign issues and salient statewide ballot propositions are also tracked over time. For poll 8902 N=1018
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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