1,744,066 research outputs found
Trykk 809
Full text link809 med tittel: Plan over plassnummerering og skilting av personvogner809 med tittel: Sammenstillingsplan for hovedtogene ; hovedpersontogene ; persontog ; ekspresstog, nattog, regiontog, intercitytog, intercity ekspresstog, utenlandsto
Corr-4a diminishes negative effects of VX-770 on VX-809-rescued I507-ATT ΔF508 CFTR.
No full textA. Mechanism of action of CFTR modulators used in our studies. B. Western blot analysis of I507-ATT and I507-ATC ΔF508 CFTR expressing HEK-293 cell lysates following vehicle control (0.15% DMSO, 16 h, 37°C) or corrector treatment (5μM VX-809, 5μM VX-770 and 5μM VX-809+5μM VX-770, 16 h, 37°C). Loading control: β-actin. C. Densitometry of band B and band C I507-ATT and I507-ATC ΔF508 CFTR levels. CFTR band B was plotted relative to vehicle control (DMSO). Band C was plotted relative to VX-809 (37°C). DMSO control, corrector VX-809 (VX-809), potentiator VX-770 (VX-770), combination (VX-809+VX-770), n = 9,9,6,3. D. Western blot analysis of I507-ATT and I507-ATC ΔF508 CFTR expressing HEK-293 cell lysates following vehicle control (0.2% DMSO, 24 h, 37°C), Corr-4a (10μM, 24 h, 37°C) or drug combination treatments (5μM VX-809+10 μM Corr-4a and 5μM VX-809+10 μM Corr-4a+5μM VX-770, 16 h, 37°C). Loading control: β-actin. E. Quantification of I507-ATT and I507-ATC ΔF508 CFTR levels. CFTR band B levels were plotted relative to vehicle control (DMSO). Band C levels were plotted relative to VX-809 (37°C). DMSO control (Ctr), corrector combination (VX-809+Corr-4a), combination of correctors and potentiator VX-770 (VX-809+Corr-4a+VX-770), n = 4. All values are means ± 1 SD. *p<0.05; **: p<0.02, significantly different from VX-809-treated sample by ANOVA, Turkey-Kramer procedure.</p
Corr-4a reverses the negative effects of VX-770 on VX-809-corrected ΔF508 CFTR half-life.
No full textA. I507-ATT ΔF508 CFTR turnover in VX-809 (5μM), VX-809+VX-770 (5μM+5μM) and VX-809+VX-770+Corr-4a (5μM +5μM+10μM) treated cells. B. I507-ATC ΔF508 CFTR turnover in VX-809 (5μM), VX-809+VX-770 (5μM+5μM) and VX-809+VX-770+Corr-4a (5μM +5μM+10μM) treated cells. Cycloheximide (CHX) (200μg/ml, 37°C) was used to inhibit protein synthesis. Cells were lysed at 0, 1 and 3 hours post CHX treatment. Representative gels are shown on top. Loading control: β-actin. CFTR band B (left) and band C (right) half-lives are plotted in the lower panels. Please see text for half-life calculation explanation. All values are means ± 1 SD. *p<0.05; **: p<0.02, significantly different by ANOVA, n = 3.</p
809
No full text1. (fol. 1r-2v) Handschriftenfragment (Vorsatzblätter) Priscianus: Institutionum grammaticarum (UBG Ms 809/Fr 01)2. (fol. 3r-120v) Priscianus: Institutionum grammaticarum libri 1-163. (fol. 121r) Handschriftenfragment (Spiegelblatt) Priscianus: Institutionum grammaticarum (UBG Ms 809/Fr 02)Titel ermittelt, Stand 2025Historische Signatur der Universitätsbibliothek Graz: 41/7 (fol. 1r)Barocke Inventarnummer des Augustiner Chorherrenstiftes Seckau: 38 (fol. 120
809
No full text1. (fol. 1r-2v) Handschriftenfragment (Vorsatzblätter) Priscianus: Institutionum grammaticarum (UBG Ms 809/Fr 01)2. (fol. 3r-120v) Priscianus: Institutionum grammaticarum libri 1-163. (fol. 121r) Handschriftenfragment (Spiegelblatt) Priscianus: Institutionum grammaticarum (UBG Ms 809/Fr 02)Titel ermittelt, Stand 2025Historische Signatur der Universitätsbibliothek Graz: 41/7 (fol. 1r)Barocke Inventarnummer des Augustiner Chorherrenstiftes Seckau: 38 (fol. 120
Union Pacific (UP) 809
No full textA photograph print showing Union Pacific (UP) 809, 4-8-4, Council Bluffs, IA
809. Kyōto
No full textIwao Seiichi, Iyanaga Teizō, Ishii Susumu, Yoshida Shōichirō, Fujimura Jun'ichirō, Fujimura Michio, Yoshikawa Itsuji, Akiyama Terukazu, Iyanaga Shōkichi, Matsubara Hideichi. 809. Kyōto. In: Dictionnaire historique du Japon, volume 13, 1987. Lettre K (3) pp. 160-161
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Street v Mountford [1985] AC 809, House of Lords
No full textEssential Cases: Land Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Street v Mountford [1985] AC 809, House of Lords. The document also includes supporting commentary from author Aruna Nair.</p
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