1,724,243 research outputs found
Southern Pacific (SP) 4362
No full textA photograph print showing the Southern Pacific (SP) 4362, 4-8-2, Colton, CA
Block Card 4362 East Way
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Dwelling (Toledo, Ohio) | Cape Cod Style | Homeville Subdivision (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio) | 4362 East Way (Toledo, Ohio
Block Card 4362 Imperial Drive
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | Dwelling | Talmadge Gardens Addition (Toledo, Ohio) | Westgate Area (Toledo, Ohio) | 4362 Imperial Drive (Toledo, Ohio
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Abstract 4362: Body mass index influences imatinib exposure in CML patients: Evidence fromTDM with adaptive dosing in real-world patients
No full textInternational audienceAbstract Imatinib remains a mainstay of treatment for elderly or frail patients with chronic myeloid leukaemia (CML). Trough levels of around 1000 ng/mL are associated with a major molecular response with acceptable tolerability. We present data from 60 adult CML patients treated with imatinib on therapeutic drug monitoring (TDM) and adaptive dosing. Mean trough levels after treatment initiation were 994.2 ±560.6 ng/mL and a large inter-patient variability was observed (CV: 56%). Only 29% of patients were in the therapeutic range. All parameters associated with corpulence (i.e. body weight, height, body surface area, body mass index (BMI)) and age were significantly associated with imatinib plasma levels on univariate analysis. Age and BMI remained the only parameters associated with trough levels on multivariate analysis. As severe toxicities have been previously reported in patients with low BMI treated with standard imatinib, we evaluated the extent to which low BMI may lead to plasma overexposure. We found a statistically significant difference in trough imatinib levels in patients with BMI<18.5, with exposure +61.5% higher than in patients with 18.5<BMI<24.9 and +76.3% higher than in patients with BMI>24.9 (p<0.05, ANOVA). After TDM with adaptive dosing, a statistically significant difference in dosing between patients was observed, with doses ranging from 200 to 700 mg (p<0.001, ANOVA). No difference in toxicity or efficacy was observed regardless of BMI after adaptive dosing (p>0.05, Chi-2 test). Our data suggest that low BMI has a significant impact on imatinib exposure, but that pharmacokinetically-guided dosing limits its clinical impact in patients. Citation Format: Paul Maroselli, Raphaelle Fanciullino, Julien Colle, Laure Farnault, Pauline Roche, Geoffroy Venton, Regis Costello, Joseph Ciccolini. Body mass index influences imatinib exposure in CML patients: Evidence fromTDM with adaptive dosing in real-world patients [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 4362
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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