1,720,999 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Ectopic fat accumulation and distant organ-specific insulin resistance
Full text link体組成計測、安定同位体標識グルコース併用高インスリン正常血糖クランプ検査にて臓器特異的インスリン抵抗性を算出、核磁気共鳴スペクトロメトリーMRSから肝細胞内脂肪含量および筋細胞内脂肪含量を定量、肝生検を試行し、肝病理像・免疫組織学的評価を行った。肝脂肪化は、肝インスリン抵抗性と正相関し、骨格筋インスリン感受性と逆相関した。骨格筋脂肪量は、骨格筋・肝臓・脂肪組織のインスリン抵抗性/感受性指標と相関せず。骨格筋脂肪量や体脂肪量は自身のインスリン感受性と関連せず。脂肪化とインスリン抵抗性の両者が他臓器と関連しているのは肝臓のみであり、肝臓が全身のインスリン抵抗性形成に中心的な役割を果たしていた。Organ-specific IR in the liver (hepatic glucose production (HGP) × fasting plasma insulin (FPI) and suppression of HGP by insulin [%HGP]), skeletal muscle (insulin-stimulated glucose disposal [Rd]), and adipose tissue (suppression of FFA by insulin [%FFA]) was measured in 69 patients with NAFLD using a euglycemic hyperinsulinemic clamp. Liver fat, intramyocellular lipid (IMCL), and body composition were measured by liver biopsy, proton magnetic resonance spectroscopy, and bioelectrical impedance analysis, respectively. Unexpectedly, fat accumulation in the skeletal muscle and adipose tissue was not associated with organ-specific IR. Instead, liver fat was associated not only with hepatic IR but also with skeletal muscle IR, suggesting a central role of fatty liver in systemic IR and that a network exists between liver and skeletal muscle.研究課題/領域番号:25860744, 研究期間(年度):2013-04-01 - 2016-03-31出典：研究課題「臓器特異的インスリン抵抗性評価系の確立とその規定因子の研究」課題番号25860744
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25860744/25860744seika/）を加工して作成金沢大学附属病院内分泌・代謝内科research repor
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
セレノプロテインPを介した脂肪酸によるインスリン抵抗性回復機序の解明
Full text linkパルミチン酸 (PA)及びエイコサペンタエン酸 (EPA)がインスリン抵抗性誘導セレノプロテインP (SeP)発現に及ぼす影響を検討。H4IIEC肝細胞において、Sepp1遺伝子発現はPAにより亢進し、EPAにより減少。SEPP1プロモーター上の応答配列はPA及びEPAに対して共通で、Sterol regulatory element (SRE)-likeな配列を有する。PAはSREBP-1c経路非依存的にSeP発現を誘導、EPAはSREBP-1c経路依存的にSeP発現を抑制。EPAはSREBP-1cの不活化を介し肝臓でのSeP発現を抑制し、全身のインスリン抵抗性を改善する可能性がある。Selenoprotein P (encoded by SELENOP in humans, Selenop in rat), a liver-derived secretory protein, induces resistance to insulin and VEGF in type 2 diabetes. The present findings demonstrate that EPA suppresses SELENOP expression by inactivating SREBP-1c in H4IIEC3 hepatocytes. Treatment with EPA caused concentration- and time-dependent reduction in SELENOP promoter activity. EPA activated AMPK; however, the inhibitory effect of EPA on SELENOP promoter activity was not canceled with an AMPK inhibitor compound C and dominant-negative AMPK transfection. Deletion mutant promoter assays and computational analysis of transcription factor-binding sites conserved among the species resulted in identification of a SRE-like site in the SELENOP promoter. A ChIP assay revealed that EPA decreases binding of SREBP-1c to the SELENOP promoter. Knockdown of Srebf1 resulted in a significant down-regulation of Selenop expression. SREBP-1c overexpression inhibited the suppressive effect of EPA.研究課題/領域番号:16K09739, 研究期間(年度):2016-04-01 - 2020-03-31出典：「セレノプロテインPを介した脂肪酸によるインスリン抵抗性回復機序の解明」研究成果報告書 課題番号16K09739
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16K09739/16K09739seika/)を加工して作成金沢大学附属病院内分泌・代謝内科research repor
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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