1,720,974 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Exploratory study of biomarkers for the development of lifestyle-related diseases by steroid metabolomics analysis
Full text link予備実験より、高血圧症の発症機序にステロイド代謝物と腸内細菌叢の関与が疑われた。そこで我々は一般住民242名を対象に、腸内細菌叢の構成と高血圧有病率を比較し、Bifidobacterium属などの存在比の低い腸内細菌叢を持つ群は、低食塩摂取でも高食塩と同等の高血圧有病率であることを示した。特にB. bifidumやB. Breveとの関連が強い傾向にあり、IL-17などのサイトカインとの関連が強く、ステロイドメタボロミクス解析の結果、いくつかのミネラロコルチコイドとの関与が示唆された。さらなる食塩感受性高血圧発生機序を解明のためにメタゲノム解析や動物モデへの移植実験を追加予定である。Hypertension causes stroke, heart disease, and kidney disease. Hypertension is classified into two groups: salt-sensitive hypertension, in which blood pressure improves with salt reduction, and salt-resistant hypertension, in which blood pressure does not. We compared the composition of the gut microbiota and the prevalence of hypertension in 242 general residents, and found that the prevalence of hypertension in the group of patients with gut microbiota low in Bifidobacterium was similar to that in the group with high salt intake, even with low salt intake. In particular, there was a strong tendency to be associated with B. bifidum and B. breve, and steroid metabolomics analysis suggested involvement with some mineralocorticoids. To further elucidate the mechanism of salt-sensitive hypertension, we plan to conduct additional metagenomic analysis and transplantation experiments into animal models.研究課題/領域番号:19K17956, 研究期間(年度):2019-04-01 – 2021-03-31出典：「ステロイドメタボロミクス解析による生活習慣病発症バイオマーカーの探索的研究」研究成果報告書 課題番号19K17956
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19K17956/19K17956seika/）を加工して作成金沢大学附属病院内分泌・代謝内科research repor
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
原発性アルドステロン症の罹病率と遺伝子学的背景及びステロイドプロファイルの検討
Full text link①2013-2017年度までの健診事業においては、原発性アルドステロン症（PA）のスクリーニング陽性の受診者が68名存在し、21名が二次健診を受診し5名がPAと診断された。②性別と年齢によりARRの分布が異なり、閉経後の女性においてARRが高値になることを示した。今後、卵巣機能、血清エストロゲンとPAの発症やARRへの影響に注目し解析を行う方針である。③質量分析計を用いて、網羅的ステロイドホルモンの高感度測定法を確立とした。誘導体化試薬のジラール試薬でステロイドのカルボニル基を誘導体化し検出感度を増加させ、10pg/mL以下の低濃度測定も可能となった。1. 68 subjects had an ARR >200. In 21 subjects who underwent captopril suppression test, PA was documented in 5 subjects in Shika Study. 2. Females subjects demonstrated significant differences in ARR between subjects with age <50 (172 ± 105) and those with age 51-60 (388 ± 531), although there were no differences in male subjects. In future, we plan to analyze an ovarian function, serum estrogen levels and influence on ARR and onset of PA. 3. We established comprehensive and high sensitive assay of the steroidal hormone the with mass spectrometer. The carbonyl group of the steroid derivatized with the Girard reagent increased detectivity of steroids, and the low-concentrated measurement less than 10pg/mL was enabled.研究課題/領域番号:17H06711, 研究期間(年度):2017-08-25 - 2019-03-31出典：「原発性アルドステロン症の罹病率と遺伝子学的背景及びステロイドプロファイルの検討」研究成果報告書 課題番号17H06711
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17H06711/17H06711seika/）を加工して作成research repor
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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