1,720,967 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Analysis of the mechanisms of induction of cancer initiation/progression by abnormal peripheral circadian rhythm using cancer mouse models

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    In the present study, we found that disruption of peripheral circadian rhythms may be involved the initiation and progression of endometrial cancer by regulating angiogenesis through the deletion of the Bmal1 gene in mouse models that spontaneously develops endometrial hyperplasia or endometrial cancer.本研究では、子宮内膜増殖症あるいは子宮体癌を自然発症するマウスモデルでBmal1遺伝子を欠損させることによって、末梢の概日リズムの乱れが、血管新生を制御して、子宮体癌の発症と進展に関与する可能性を見出した。研究課題/領域番号:20K21651, 研究期間(年度):2020-07-30 – 2022-03-31出典:研究課題「がん自然発症マウスを用いた末梢概日リズム異常によるがん発生・進展誘導機構の解析」課題番号20K21651 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-20K21651/20K21651seika/)を加工して作成金沢大学学際科学実験センターresearch repor

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

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    新たな子宮肉腫マウスモデルを用いた肉腫化抑制因子の同定と新規分子標的治療への応用

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    本研究従事者らは、これまでに子宮特異的にPten遺伝子を欠損させたPten-PRcreマウスにプロゲステロンを連続投与することによって、子宮間質肉腫マウスモデルを新たに作出することに成功した。本研究では、このマウスモデルを使用し、子宮肉腫の発生は上皮の作用によって左右されることを実験的に明らかにした。さらに、肉腫発生に関わるいくつかの因子を明らかとした。We previously established a novel uterine sarcoma mouse model by long-term treatment of progesterone to uterine specific Pten null mice. In this research, we found that normal Pten in uterine epithelium is essential to repress initiation of uterine stromal sarcoma in mouse. We also found some candidates which plays important role for initiation of uterine stromal sarcoma.研究課題/領域番号:18K19607, 研究期間(年度):2018-06-29 - 2020-03-31出典:「新たな子宮肉腫マウスモデルを用いた肉腫化抑制因子の同定と新規分子標的治療への応用」研究成果報告書 課題番号18K19607 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18K19607/18K19607seika/)を加工して作成金沢大学学際科学実験センター実験動物研究施設research repor

    子宮選択的Pten変異による体癌自然発症マウスを用いた増悪因子と作用機序の解析

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    本研究従事者らはこれまで子宮部位特異的にPten遺伝子を欠損させることによって子宮体癌マウスモデルを確立してきた。本研究ではこれらのマウスモデルを使用し、子宮体癌(上皮)の発生には間質の作用によって左右されることを実験的に明らかにするとともに、間質のがん化もまた上皮の作用によって左右される可能性を示唆した。さらに子宮体癌発生・進行に関わるいくつかの因子を明らかとした。Using our new endometrial cancer mouse models, we found that the Pten in uterine stroma represses malignant transformation of Pten null uterine epithelium. We further demonstrated that Pten in uterine epithelium is essential to repress uterine stromal sarcoma in mouse model. We also found some aggravating factors for endometrial cancer initiation and progression in this study.研究課題/領域番号:16H05470, 研究期間(年度):2016-04-01 - 2019-03-31出典:研究課題「子宮選択的Pten変異による体癌自然発症マウスを用いた増悪因子と作用機序の解析」課題番号16H05470 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16H05470/16H05470seika/)を加工して作成research repor

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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