1,720,967 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Get PDF
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

    Get PDF
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

    Get PDF
    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Involvement of neuroinflammation in the negative affective component of chronic pain: Effect of resolvin D1, an anti-inflammatory lipid mediator

    Get PDF
    本研究では、抗炎症性脂質レゾルビンD1(RvD1)が、慢性疼痛に伴う脳内炎症及び精神症状に有効か否かを明らかにすることを目的として解析を行った。炎症によるうつ病発症を模倣したリポポリサッカライド(LPS)誘発うつ病モデルにおいて、RvD1及びレゾルビンD2(RvD2)側脳室内投与がmTOR経路活性化を介して抗うつ作用を示すことが明らかとなった。今後、慢性疼痛モデル動物を用いて、RvD1及びRvD2が慢性疼痛による精神症状に有効であるか検討を行う必要がある。In the present study, we aimed to assess the effects of resolvin D1 (RvD1), an anti-inflammatory lipid mediator, on chronic pain-induced neuroinflammation and the negative affective states. Intracerebroventricular injections of RvD1 or resolvin D2 (RvD2) exerted antidepressant-like effects against lipopolysaccharide-induced depression-like behavior, a rodent model of inflammation-induced depression, via activation of mTOR signaling. Further investigations are required to verify whether RvD1 and RvD2 improve the negative affective states in a chronic pain model.研究課題/領域番号:25860060, 研究期間(年度):2013-04-01 – 2015-03-31出典:研究課題「慢性疼痛に伴う精神症状における脳内炎症の関与と抗炎症性脂質レゾルビンD1の有用性」課題番号25860060 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-25860060/25860060seika/)を加工して作成金沢大学医薬保健研究域薬学系 / 北海道大学research repor

    Dispelling the Myths Behind First-author Citation Counts

    Get PDF
    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

    No full text
    Nao informado

    Mechanisms underlying the antidepressant-like effects of intranasal administration of resolvins in animal models of depression and treatment-resistant depression

    Get PDF
    In this study, we found that intranasal (i.n.) administration of resolvin E1 (RvE1), a bioactive lipid mediator derived from EPA, produces antidepressant-like effects via BDNF/VEGF release and the subsequent activation of mTORC1 in the medial prefrontal cortex (mPFC) in mouse models of depression, including a treatment-resistant depression model. We also found that intraperitoneal and oral administration of o-BZ-RvE2, a metabolically stable analog of resolvin E2, an EPA metabolite, produces antidepressant-like effects via mTORC1 activation in the mPFC. These findings suggest that i.n. administration is a viable and promising route for the delivery of unstable resolvins to the brain and can pave the way for the application of resolvins in the treatment of depression. Moreover, this study suggests that stable resolvin analogs could be lead compounds for novel antidepressants.本研究により、エイコサペンタエン酸(EPA)の活性代謝物レゾルビンE1(RvE1)の経鼻投与が内側前頭前野(mPFC)でのBDNF、VEGF遊離とmTORC1活性化を介して抗うつ作用を示すことが明らかになった。また、RvE1経鼻投与は既存薬に抵抗性を示すうつ病モデルにも抗うつ作用を示した。さらに、レゾルビンE2安定化誘導体o-BZ-RvE2の経口投与がmPFC内mTORC1活性化を介して抗うつ作用を示すことを見出した。以上より、化学的に不安的なレゾルビン類を経鼻投与で効率的かつ非侵襲的に脳内に送達するか、安定化誘導体を創製することで新たな抗うつ薬としての臨床応用につながる可能性が考えられた。研究課題/領域番号:19K07120, 研究期間(年度):2019-04-01 – 2022-03-31出典:研究課題「治療抵抗性うつ病に対するレゾルビン類経鼻投与の治療効果とその作用機序の解明」課題番号19K07120 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19K07120/19K07120seika/)を加工して作成金沢大学医薬保健研究域薬学系research repor

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

    No full text
    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
    corecore