1,747,941 research outputs found
Inhibitors AG-1478 and sorafenib.
(A) Huh-7.5 spheroids were serum starved, incubated with 5 μM AG-1478 or sorafenib for 2 hr if indicated, infected with concentrated HCV with 5 μM AG-1478 or sorafenib for 1 hr at 4°C, shifted to 37°C, processed with Matrigel cell recovery solution, and lysed at 120 min post temperature shift. Lysate samples were immunoblotted for the indicated proteins. (B) Huh-7.5 cells were serum starved, incubated with DMSO or 5 μM AG-1478 for 2 hr, stimulated with 40 ng/mL EGF with DMSO or AG-1478 for 15 min and lysed. EGFR was immunoprecipitated from the lysate samples and immunoblotted for the indicated proteins. (C) Huh-7.5 cells were electroporated with HCV RNA. 24 hr post electroporation, medium was replaced with 5 μM sorafenib or AG-1478 in medium. 48 hr post electroporation, viral supernatants were collected, and infectious viral titers were determined. Mean +/- SD. (TIF)</p
Insulin resistance and hepatitis C virus: a case-control study of non-obese, non-alcoholic and non-steatotic hepatitis virus carriers with persistently normal serum aminotransferase
Author Posting. © The Authors 2008 This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in Liver International, 28(8):1104-1111. https://doi.org/10.1111/j.1478-3231.2008.01737.xArticleLIVER INTERNATIONAL. 28(8):1104-1111(2008)journal articl
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Insulin resistance and hepatitis C virus: a case-control study of non-obese, non-alcoholic and non-steatotic hepatitis virus carriers with persistently normal serum aminotransferase
Author Posting. © The Authors 2008 This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in Liver International, 28(8):1104-1111. http://dx.doi.org/10.1111/j.1478-3231.2008.01737.xArticleapplication/pdfLIVER INTERNATIONAL. 28(8):1104-1111(2008)journal articl
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Monumenta Borgia VI (1478-1551). [Reseña]
Reseña de: Enrique GARCÍA HERNÁN (ed.), Monumenta
Borgia VI (1478-1551), Generalitat Valenciana-
Institutum Historicum Societatis Iesu («Monumenta
Historica Societatis Iesu», 156), Valencia-
Roma 2003, 751 pp
Tver Gospel of 1478 (codicology and palaeography)
The codicological and paleographic description of the Tver Gospel of 1478, a dated Tetraevangelia manuscript, has been performed. The place and time of the manuscript creation are indicated in the copyist’s record at the end of the book (f. 322v.). The Gospel is kept in the Fund of Rare Books of the National Museum of the Republic of Tatarstan, no. 8772. It is a manuscript in quarto, 322 ff., written in the same handwriting, decorated with miniatures, initials, the tri-color medallions, etc. The text is well structured. The Gospels of the apostles are separated from each other by colored miniatures of the evangelists, made in the artistic manner of the Tver School of Painting. The manuscript is written in a clear half-text of the second half of the 15th century on paper with a “bull’s head” watermark. The book was restored in the late 18th century and is well preserved. The value of the dated and geographically confined texts to historical linguistics and culture, history of Church literature, etc. has been established
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