1,720,965 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
HLA-B*54:01陽性造血不全患者における免疫病態の解明
Full text link本研究では、HLA-B5401欠失血球陽性の再生不良性貧血（再不貧）の免疫病態と、HLA-B5401が提示する自己抗原を明らかにすることを目的とした。HLA-B5401欠失血球陽性の再不貧患者から、抗原特異的に優勢に増殖しているT細胞レセプター（T-cell receptor: TCR）の配列を同定した。また、再不貧患者のHLA-Aアレル、Bアレルに共通してみられるexon1領域のミスセンス変異を同定し、この変異を高感度で検出できるdroplet digital PCRを開発した。HLA-Bアレルにおいて、HLA-B5401の変異はHLA-B4002についで2番目に多いことが明らかになった。The purpose of the study is to understand pathophysiology in aplastic anemia (AA) patients with HLA-B*54:01 lacking cells and autoantigens presented by HLA-B5401. We identified T-cell receptor sequence in AA patients with HLA-B5401 lacking cells. We also identified a common nonsense mutation in exon 1 of different HLA-A and -B alleles in HLA-lacking granulocytes from AA patients. A droplet digital PCR (ddPCR) assay revealed that HLA-B*54:01 mutation was the second most frequent HLA-B allele in AA patients.研究課題/領域番号:19K17823, 研究期間(年度):2019-04-01 - 2021-03-31出典：「HLA-B*54:01陽性造血不全患者における免疫病態の解明」研究成果報告書 課題番号19K17823
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19K17823/19K17823seika/）を加工して作成research repor
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
再生不良性貧血を発症させるT細胞シグナルパスウェイの同定
Full text link再生不良性貧血の類縁疾患である骨髄不全型PNH（発作性夜間ヘモグロビン尿症）の患者検体と健常人のシークエンスデータを用いて解析を行ったところ、TNFR, IGF1, NOTCH, AP-1, ATF2 pathwayなどのパスウェイに関連した遺伝子群の発現が有意に変化していた。さらにそれらの候補遺伝子群の中から、JUN, TNFAIP3, TOB1, GIMAP4,GIMAP6, TRMT112, NR4A2, CD69,TNFSF8などのT細胞の活性化・制御に関わるような遺伝子の発現がそれぞれのT細胞サブセットにおいて有意に変化していることが、qPCRやフローサイトメトリーにより確認された。To identify aberrant molecular mechanisms involved in immune targeting of hematopoietic stem cells in bone marrow, we applied RNA-seq to examine the transcriptome of T cell subsets from AA/PNH patients and healthy control subjects. Differentially expressed gene analysis in four different T cell subsets from PNH and healthy control subjects showed distinct transcriptional profiles, depending on the T cell subsets. By pathway analysis, we identified novel signaling pathways in T cell subsets, including increased gene expression involved in TNFR, IGF1, NOTCH, AP-1, and ATF2 pathways. Dysregulation of several candidate genes (JUN, TNFAIP3, TOB1, GIMAP4, GIMAP6, TRMT112, NR4A2, CD69, and TNFSF8) was validated by quantitative real-time RT-PCR and flow cytometry.研究課題/領域番号:17K16184, 研究期間(年度):2017-04-01 - 2019-03-31出典：研究課題「再生不良性貧血を発症させるT細胞シグナルパスウェイの同定」課題番号17K16184
（KAKEN：科学研究費助成事業データベース（国立情報学研究所））
（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K16184/17K16184seika/）を加工して作成research repor
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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