19683 research outputs found
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Public involvement in Australian clinical trials: A systematic review
No full textBackground: Public involvement enhances the relevance, quality, and impact of research. There is some evidence that public involvement in Australian research lags other countries, such as the United Kingdom. The purpose of the systematic review was to establish the rates and describe the characteristics of public involvement in Australian clinical trials. Methods: We reviewed evidence of public involvement in all Australian randomised controlled trials published in the first 6 months of 2021. To determine the quality of public involvement, we used the five-item short-form version of the Guidance of Reporting Involvement Patients and the Public, version 2. Results: In total, 325 randomised controlled trials were included, of which 17 (5%) reported any public involvement. Six trials reported public involvement in setting the research aim and seven in developing study methods. The authors of one study reflected on the overall role and influence of public involvement in the research. Conclusion: Rate of public involvement in Australian clinical trials is seemingly substantially lower than those reported in countries with similar advanced public health care systems, notably the United Kingdom. Our observations may be explained by a lack of researcher skills in how to involve the public and the failure by major funding agencies in Australia to mandate public involvement when deciding on how to award grant funding
On strengthening trust and integrity in online giving platforms
No full texthttps://www.pc.gov.au/submissions-search?collection=productivity-commission-sub-web&f.Inquiry|T=philanthropy&query=Matthew+Wade </p
Affirmation, Friendship, and Volunteerism: Understanding and Facilitating what Makes LGBTQA+ Young People in Australia Feel Good About Themselves
No full textIntroduction: Lesbian, gay, bisexual, trans, queer or asexual (LGBTQA+) young people are at heightened risk of suicidality and psychological distress. Interventions in various forms are required to address this issue, which should be informed by the strengths, capacity and insight of LGBTQA+ young people. Methods: An online survey was promoted to LGBTQA+ young people (aged 14–21) via targeted social media advertising and community organisation dissemination, in late 2019. In addition to a range of health and wellbeing questions, all participants were asked, ‘What makes you feel good about yourself?’ The open-text responses were subject to a detailed, inductive thematic analysis. Results: In total, 4751 young people provided a short answer response to the question of what makes them feel good about themselves. The length of responses ranged from a few words to several paragraphs. Six key themes were identified. These included LGBTQA+ young people finding value in connection with significant others and finding affirmation for their gender and sexuality through their presentation and engagement with the world. In addition, participants talked about how they liked to engage with people they identified with or saw as role models, and how their creative outlets or making a positive difference in the world (e.g., through volunteering) helped them feel good about themselves. Conclusions: While ensuring that young LGBTQA+ people have access to mental health services and social/support programs is important, it is also essential that we acknowledge young people’s agency and the significance of everyday, informal acts which support young LGBTQA+ people to achieve desires for connection, acceptance, contribution, belonging and self-expression. Policy Implications: Findings reported in this paper offer some valuable insights for policy and programming, particularly in acknowledging and centring young people’s agency and capacity to make decisions and take action to express themselves, to find community and affirm their identity
Hyper-Automated Artificial Intelligence Platforms for Complex Spatiotemporal Digital Environments
No full textA thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the La Trobe Business School, La Trobe University, Victoria, Australia.</p
Hierarchical adaptive evolution framework for privacy-preserving data publishing
No full textThe growing need for data publication and the escalating concerns regarding data privacy have led to a surge in interest in Privacy-Preserving Data Publishing (PPDP) across research, industry, and government sectors. Despite its significance, PPDP remains a challenging NP-hard problem, particularly when dealing with complex datasets, often rendering traditional traversal search methods inefficient. Evolutionary Algorithms (EAs) have emerged as a promising approach in response to this challenge, but their effectiveness, efficiency, and robustness in PPDP applications still need to be improved. This paper presents a novel Hierarchical Adaptive Evolution Framework (HAEF) that aims to optimize t-closeness anonymization through attribute generalization and record suppression using Genetic Algorithm (GA) and Differential Evolution (DE). To balance GA and DE, the first hierarchy of HAEF employs a GA-prioritized adaptive strategy enhancing exploration search. This combination aims to strike a balance between exploration and exploitation. The second hierarchy employs a random-prioritized adaptive strategy to select distinct mutation strategies, thus leveraging the advantages of various mutation strategies. Performance bencmark tests demonstrate the effectiveness and efficiency of the proposed technique. In 16 test instances, HAEF significantly outperforms traditional depth-first traversal search and exceeds the performance of previous state-of-the-art EAs on most datasets. In terms of overall performance, under the three privacy constraints tested, HAEF outperforms the conventional DFS search by an average of 47.78%, the state-of-the-art GA-based ID-DGA method by an average of 37.38%, and the hybrid GA-DE method by an average of 8.35% in TLEF. Furthermore, ablation experiments confirm the effectiveness of the various strategies within the framework. These findings enhance the efficiency of the data publishing process, ensuring privacy and security and maximizing data availability
Lines of Exchange: Australian and New Zealand Women on Carnegie and Fulbright Programme Awards c. 1930s-1980s
No full textNarratives of international educational exchange programmes such as the US–sponsored Fulbright and the Commonwealth–centred Carnegie grants reveal the formative role these exchanges played in extending the geographical, scholarly, and professional boundaries of women’s worlds. Notably, these award schemes influenced, shaped and expanded the career aspirations and professional experiences of a group of women from Australia and New Zealand. In this article, we take up the question of the distinctive opportunities each programme presented for women awardees and consider their differing experiences primarily due to the specific programme on which they embarked. We argue that the extent to which participation in an exchange programme might have provided benefits to individual Australian and New Zealand women could also become the spur for awardees to advocate for an expansion of opportunities for other women. Furthermore, we consider whether hidden obstacles existed that hindered women’s career pathways and successes
The impact of plant-derived fire management prescriptions on fire-responsive bird species
No full textIn fire-prone regions, the occurrence of some faunal species is contingent on the presence of resources that arise through post-fire plant succession. Through planned burning, managers can alter resource availability and aim to provide the conditions required to promote biodiversity. Understanding how species occurrence changes at different spatial and temporal scales after fire is essential to achieve this goal. However, many fire prescriptions are guided primarily by the responses of fire-sensitive plants when setting tolerable fire intervals. This approach assumes that maintaining floristic diversity will satisfy the requirements of fauna. We surveyed bird species in two semi-arid vegetation types across an environmental gradient in south-eastern Australia. We conducted four surveys at each of 253 sites across a 75-year chronosequence of time since fire and used generalized additive mixed models to examine changes in the occurrence of birds in response to time since fire. Model predictions were compared to plant-derived fire prescriptions currently guiding fire management in the region. Time since fire was a significant predictor for 18 of 28 species modeled, in at least one vegetation type, over a gradient of 1.3 degrees of latitude. We detected considerable variation in the responses of some species, both between vegetation types and geographically within a vegetation type. Our evaluation of plant-derived fire prescriptions suggests that the intervals considered acceptable for maintaining floristic diversity may not be sustainable for populations of birds requiring longer unburnt vegetation, with six of the 12 species assessed attaining a mean occurrence probability of 20.3% by the minimum tolerable fire interval, and 57.3% by the maximum tolerable fire interval, in their respective vegetation types. Our findings highlight the potential vulnerability of fire-responsive bird species if fire prescriptions are applied in a manner that fails to account for the slow development of habitat resources needed by some species, and the variation detected within the responses of species. This highlights the need for species-specific data collected at an appropriate spatial scale to inform management plans.</p
Isolation of a PRD1-like phage uncovers the carriage of three putative conjugative plasmids in clinical Burkholderia contaminans
No full textThe Burkholderia cepacia complex (Bcc) is a group of increasingly multi-drug resistant opportunistic bacteria. This resistance is driven through a combination of intrinsic factors and the carriage of a broad range of conjugative plasmids harbouring virulence determinants. Therefore, novel treatments are required to treat and prevent further spread of these virulence determinants. In the search for phages infective for clinical Bcc isolates, CSP1 phage, a PRD1-like phage was isolated. CSP1 phage was found to require pilus machinery commonly encoded on conjugative plasmids to facilitate infection of Gram-negative bacteria genera including Escherichia and Pseudomonas. Whole genome sequencing and characterisation of one of the clinical Burkholderia isolates revealed it to be Burkholderia contaminans. B. contaminans 5080 was found to contain a genome of over 8 Mbp encoding multiple intrinsic resistance factors, such as efflux pump systems, but more interestingly, carried three novel plasmids encoding multiple putative virulence factors for increased host fitness, including antimicrobial resistance. Even though PRD1-like phages are broad host range, their use in novel antimicrobial treatments shouldn't be dismissed, as the dissemination potential of conjugative plasmids is extensive. Continued survey of clinical bacterial strains is also key to understanding the spread of antimicrobial resistance determinants and plasmid evolution
Developing Digital Competency in Health and Physical Education: When Digital Literacy Meets Physical Literacy
No full textThis is part of a volume which constitutes selected papers presented during the Second International Conference on New Media Pedagogy: Research Trends, Methodological Challenges, and Successful Implementations, NMP 2023, held in Cracow, Poland, in November 2023.</p
Care, kindness and collegiality in occupational therapy practice and academic life
No full textThis paper explores the reflections of occupational therapy academics about the experience of kindness in academic and professional life. Data were derived from a reflective group conversation in the context of a larger overarching research project exploring occupational therapy academic development. The findings elaborate how kindness and care played out for us as participant-researcher academics, including how it was mediated by expression of values and behaviours in our roles, and how we experienced the values and behaviours of others in the academy. We found that degrees of kindness and care were distributed along a continuum from more kind to less kind. A notable aspect of our conceptualisation of kindness involves recognising others' potential and a willingness to work collectively. We argue that it is critical to create and maintain communities that value and are capable of acting with authentic care and kindness. Prioritising our time to engage in emotion-based, relational work beyond ‘duty of care’ is vital to support collective success and longevity in the academy. Recognition of, and action to challenge, the forces that erode kindness and care are vital next steps in creating academic and professional contexts that will support our flourishing